Search clinical trials for: persistent disease activity

Total 386551 results

Otsuka America Pharmaceutical

Completed

A Study of Multiple Doses of Vesnarinone in Advanced HIV Disease

HIV Infections

United States
National Center for Research Resources (NCRR)
Cystic Fibrosis Foundation

Completed

Bone Health of People With Cystic Fibrosis

Cystic Fibrosis

United States
Astra USA

Completed

An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies

HIV Infections | Herpes Simplex

United States
Rhone-Poulenc Rorer

Completed

Open-Label "Compassionate" Use Study of Spiramycin for the Treatment of Diarrhea Due to Chronic Cryptosporidiosis in Immunocompromised Patients

HIV Infections | Cryptosporidiosis

United States
Pfizer

Completed

An Open-Label Study of the Use of Azithromycin in Patients With Symptomatic Disseminated Mycobacterium Avium-Intracellulare Complex (MAC) Infection Failing Current Therapy

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pfizer

Completed

A Randomized Study of Daily and Intermittent Prophylactic Regimens for the Prevention of Disseminated Mycobacterium Avium Complex (MAC) and Fungal Infections in HIV-Infected Patients

HIV Infections | Mycoses | Mycobacterium Avium-Intracellulare Infection

United States
Pharmacia and Upjohn

Completed

A Double-Blind, Randomized, Dose Response Study of Three Doses of Delavirdine Mesylate (U-90152S) in Combination With Zidovudine (ZDV) Versus ZDV Alone in HIV-1 Infected Individuals With CD4 Counts of 200-500mm3

HIV Infections

United States, Puerto Rico
National Center for Research Resources (NCRR)
University of Michigan

Completed

Study of the Effect of Growth Hormone-Releasing Hormone Antagonist on Growth Hormone Release in Acromegaly

Acromegaly
National Center for Research Resources (NCRR)
Oregon Health and Science University

Unknown

Study of Hypercortisolism in Cushing's Syndrome and Stress-Induced Pseudo-Cushing's Syndrome

Cushing's Syndrome

United States
National Center for Research Resources (NCRR)
Oregon Health and Science University

Unknown

Phase II Study of Dietary Cholesterol for Smith-Lemli-Opitz Syndrome

Smith-Lemli-Opitz Syndrome

United States
National Center for Research Resources (NCRR)
Brigham and Women's Hospital

Completed

Study of Prevalence and Clinical Phenotype in Patients With Glucocorticoid-Remediable Aldosteronism

Hyperaldosteronism

United States
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Study of Homocysteine Metabolism in Homocystinuria

Homocystinuria
NeurogesX

Terminated

An Open-Label Extension Study of NGX-4010 for the Treatment of Neuropathic Pain

HIV Infections | Pain | Diabetes Mellitus | Diabetic Neuropathies | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster | Polyneuropathies
Glaxo Wellcome

Completed

A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine

HIV Infections | Toxoplasmosis, Cerebral

United States, Canada
Immunobiology Research Institute

Completed

A Study of Timunox (Thymopentin) in HIV-Infected Patients Receiving Other Anti-HIV Drugs

HIV Infections

United States
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome

Polycystic Ovary Syndrome | Acanthosis Nigricans
National Center for Research Resources (NCRR)
University of Texas

Completed

Studies in Porphyria IV: Gonadotropin-Releasing Hormone (GnRH) Analogues for Prevention of Cyclic Attacks

Porphyria

United States
Eunice Kennedy Shriver National Institute of Child...
Rockefeller University

Completed

Phase II Randomized Study of Tin Mesoporphyrin for Neonatal Hyperbilirubinemia

Hyperbilirubinemia | Glucosephosphate Dehydrogenase Deficiency | Hemolytic Disease of Newborn

United States
National Institute of Neurological Disorders and...

Completed

Timing of Levodopa Treatment in Parkinson's Disease

Parkinson's Disease

United States
Royal Brisbane and Women's Hospital

Unknown

Peripheral Venous Catheter Trial: 3 Day Versus No Routine Change

Phlebitis

Australia
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Intervention to Improve Asthma Management/Prevention

Lung Diseases | Asthma
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Phase I/II Study of Monoclonal Factor IX Concentrate for Factor IX Deficiency

Hemophilia B | Factor IX Deficiency
Wyeth-Lederle Vaccines

Completed

A Study of GENEVAX-HIV, a Possible Vaccine

HIV Infections | HIV Seronegativity

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Infants and Children Infected With or at Risk for HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Azidothymidine (AZT) in the Treatment of HIV Infection in Patients Receiving a Bone Marrow Transplant

HIV Infections | Lymphoma, Non-Hodgkin

United States
Wyeth-Lederle Vaccines

Completed

Safety and Effects of Giving a New HIV Vaccine (GENEVAX-HIV) to HIV-Negative Volunteers

HIV Infections | HIV Seronegativity

United States
Glaxo Wellcome

Completed

A Study to Compare the Safety and Effectiveness of Two Dosing Schedules of Lamivudine in Combination With Two Other Anti-HIV Drugs

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Multicenter Study of the Safety and Immunogenicity of MN rgp120/HIV-1 Vaccine Given Either Alone or in Combination With IIIB rgp120/HIV-1 Vaccine in Healthy Adult Subjects (NOTE: Original Study Extended ONLY for Patients Previously Enrolled on VEU 009)

HIV Infections

United States
National Center for Research Resources (NCRR)

Completed

Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States
Centaur Pharmaceuticals

Unknown

Safety and Effectiveness of Giving CPI-1189 to HIV-Infected Patients With AIDS Dementia

HIV Infections

United States
Agency for Healthcare Research and Quality (AHRQ)

Completed

Surgical Treatments Outcomes Project for Dysfunctional Uterine Bleeding (STOP-DUB)

Menorrhagia | Uterine Bleeding
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants

Sepsis | Necrotizing Enterocolitis

United States
Gilead Sciences

Completed

Tenofovir Disoproxil Fumarate (TDF) in HIV-1 Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

Safety and Effectiveness of an Anti-HIV Drug Combination in HIV-Positive Patients Who Have Failed Previous Treatment With Protease Inhibitors

HIV Infections

United States
PPD

Unknown

Differences Between Women and Men Taking a Combination of Indinavir, Ritonavir, Enteric-Coated Didanosine, and Stavudine Who Previously Took Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
Valentis

Completed

Trial of VLTS-589 in Subjects With Intermittent Claudication

Intermittent Claudication | Peripheral Vascular Disease

United States
Daiichi Pharmaceuticals

Completed

A Phase I Trial of Tecogalan Sodium ( DS-4152 ) Administered as an Infusion Weekly x 4

HIV Infections | Sarcoma, Kaposi

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, United Kingdom
Glaxo Wellcome

Unknown

Comparison of GW433908 and Nelfinavir in HIV Patients Who Have Not Had Antiretroviral Therapy

HIV Infections

United States
U.S. Bioscience

Completed

A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate (Neutrexin) With Leucovorin Protection for European Adult Patients (>= 13 Years Old) With Pneumocystis Carinii Pneumonia

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
National Eye Institute (NEI)

Unknown

Macular Photocoagulation Study (MPS)

Macular Degeneration | Choroidal Neovascularization | Histoplasmosis
Hoffmann-La Roche

Completed

An Open-Label Safety Study of Oral Ganciclovir Maintenance Treatment of CMV Retinitis in People With Limited Venous Access

HIV Infections | Cytomegalovirus Retinitis

United States
Triangle Pharmaceuticals

Completed

A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive

HIV Infections

United States
Pfizer

Completed

A Study of Azithromycin in HIV-Infected Patients

HIV Infections | Bacterial Infections

United States
Bellus Health Inc
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy

Stroke | Neurologic Diseases, General

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Norplant and Irregular Bleeding/Spotting

Periodontal Disease | Endometrial Bleeding

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Low Phenylalanine Diet for Mothers With Phenylketonuria (PKU)

Phenylketonuria

United States
Wageningen University
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Oral Vitamin B12 Supplementation and Cognitive Performance in Elderly People

Cognitive Decline | Cognitive Symptoms

Netherlands
Unimed Pharmaceuticals

Completed

A Study of Nitazoxanide in the Treatment of AIDS-Related Diarrhea

HIV Infections

United States
Baker Norton Pharmaceuticals

Completed

Paclitaxel in Advanced Refractory Kaposi's Sarcoma (AIDS-KS): A Phase II Trial of Paclitaxel From Baker Norton Pharmaceuticals

HIV Infections | Sarcoma, Kaposi

United States

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