Clinical Trials Sponsored by Factor Therapeutics Ltd.

Total 474 results

Spero Therapeutics
Clinical Network Services (CNS) Pty Ltd

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of SPR206 in Healthy Volunteers

Healthy Volunteers

Australia
First Affiliated Hospital Xi'an Jiaotong University
Eureka Therapeutics Inc.; Aeon Therapeutics (Shanghai) Co., Ltd.

Completed

ET1402L1-ARTEMIS™2 T Cells in Alpha Fetoprotein (AFP) Expressing Hepatocellular Carcinoma

Liver Neoplasms | Hepatocellular Carcinoma | Liver Cancer | Metastatic Liver Cancer

China
Heidelberg University
Hector-Stiftung; Schwabe-Wenex International Ltd; Cefak KG, Kempten; Ursapharm,...

Completed

Complementary Therapies for the Reduction of Side Effects During Chemotherapy for Breast Cancer

Breast Cancer

Germany
AIM Vaccine Co., Ltd.
Ningbo Rongan Biological Pharmaceutical Co. Ltd.; LiveRNA Therapeutics Inc.

Recruiting

Clinical Trail of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021) in Participants Aged 18 Years and Older

SARS-CoV-2

Pakistan
AIM Vaccine Co., Ltd.
Ningbo Rongan Biological Pharmaceutical Co. Ltd.; LiveRNA Therapeutics Inc.

Not yet recruiting

Clinical Study of SARS-CoV-2 Variant mRNA Vaccine in Healthy Participants

SARS-CoV-2
Zai Lab (Shanghai) Co., Ltd.
Mirati Therapeutics Inc.

Active, not recruiting

The Clinical Trial to Evaluate the Pharmacokinetics and Safety of MRTX849 in Patients With Advanced Solid Tumors

Advanced or Metastatic Solid Tumor

China
Changzhou No.2 People's Hospital
Rui Therapeutics Co., Ltd

Not yet recruiting

An Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Primary Immune Thrombocytopenia

Thrombocytopenia Alloimmune
Children's Hospital of Fudan University
CorrectSequence Therapeutics Co., Ltd

Recruiting

Base-edited Autologous Hematopoietic Stem Cell Transplantation in Treating Patients With β-thalassemia Major

Beta-Thalassemia

China
Zhejiang Provincial People's Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Personalized Neoantigen Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

Resectable Pancreatic Cancer

China
Turning Point Therapeutics, Inc.
Zai Lab (Shanghai) Co., Ltd.

Recruiting

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements (TRIDENT-1)

Locally Advanced Solid Tumors | Metastatic Solid Tumors

United States, China, Japan, Australia, Belgium, Canada, Denmark, France, Germany, Hong Kong, Hungary, Italy, Korea, Democratic People's Republic of, Korea, Republic of, Netherlands, Poland, Singapore, Spain, Taiwan, United Kingdom
Five Prime Therapeutics, Inc.
Zai Lab (Shanghai) Co., Ltd.

Completed

A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (mFOLFOX6) in Gastric/Gastroesophageal Junction Cancer (FIGHT)

Gastric Cancer

United States, Spain, China, Italy, Korea, Republic of, Portugal, Taiwan, Japan, Turkey, France, Hungary, Thailand, Germany, Poland, Australia, Belgium, Romania, United Kingdom
Base Therapeutics (Shanghai) Co., Ltd.
Shanghai 10th People's Hospital

Enrolling by invitation

Safety and Efficacy of NK510 to Treat Gastric Cancer

Gastric Cancer

China
Paracrine Therapeutics Dermatology Pte. Ltd.
National University Hospital, Singapore

Completed

Safety and Tolerability Study of MSC Exosome Ointment

Psoriasis

Singapore
Imperial College London
Medical Research Council; Atopix Therapeutics, Ltd.

Completed

Effect of OC459 on the Response to Rhinovirus Challenge in Asthma

Picornaviridae Infections | Asthma | Common Cold | Rhinovirus

United Kingdom
Landmark Medical Centre Sdn Bhd
CytoMed Therapeutics Pte Ltd

Unknown

MSC Infusion for Anti-aging and Regenerative Therapy (REGEN)

Aging Well | Regenerative Medicine

Malaysia
ACEA Therapeutics, Inc.
Hangzhou ACEA Pharmaceutical Research Co., Ltd.

Unknown

Study of AC0058TA in Patients With Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

United States
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
LENZ Therapeutics, Inc

Recruiting

Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Presbyopia

Eye Diseases | Presbyopia | Miosis | Near Vision

China
AIO-Studien-gGmbH
Roche Pharma AG; Immodulon Therapeutics Ltd

Recruiting

Atezolizumab in Patients With MSI-h/MMR-D Stage III Colorectal Cancer Ineligible for Oxaliplatin (ANTONIO)

Colorectal Cancer

Germany
Innovative Cellular Therapeutics Co., Ltd.
Anhui Provincial Cancer Hospital

Not yet recruiting

CART Therapy in Digestive System Tumors

Malignant Neoplasms of Digestive Organs

China
Weill Medical College of Cornell University
NeoTX Therapeutics Ltd.

Withdrawn

Naptumomab Estafenatox in Combination With Pembrolizumab Preceded by Obinutuzumab in Patients With Urothelial Cancers

Urothelial Carcinoma

United States
Zhejiang Provincial People's Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Completed

Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreatic Carcinoma

China
F-star Therapeutics, Inc.
CSI Medical Research Pte Ltd

Terminated

Evaluating the Effects of Inarigivir on Immune Response and Viral Markers in Chronic Hepatitis B Patients

Hepatitis B | Hepatitis B, Chronic | HBV

Singapore
Horizon Therapeutics, LLC

Completed

To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs)

Urea Cycle Disorders

United States, Canada
BioSync Scientific Pvt. Ltd.
Cardialysis BV; MIV Therapeutics Inc.

Unknown

Hydroxyapatite Active Pro Healing Clinical Trial Program (HApFIM)

Coronary Artery Disease
Changhai Hospital
Shanghai Ultra-T Immune Therapeutics Co. LTD

Not yet recruiting

A Clinical Study on the Safety and Efficacy of CAR-T Therapy for the TM4SF1-positive Tumors of Digestive System

Digestive Tumor
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
LENZ Therapeutics, Inc

Completed

Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia

Presbyopia

China
Enlivex Therapeutics Ltd.
Cato Research; Accelsiors CRO & Consultancy Services

Active, not recruiting

A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients

Sepsis | Intraabdominal Infections | Cholecystitis, Acute | Urinary Tract Infections | Community-acquired Pneumonia | Cholangitis Acute

Netherlands, Israel, France, Belgium, Spain
Taiwan Bio Therapeutics Co., Ltd.
A2 Healthcare Taiwan Corporation

Active, not recruiting

Chondrochymal® for Subjects With Knee Osteoarthritis (Knee OA)

Osteoarthritis, Knee

Taiwan
Vascular Biogenics Ltd. operating as VBL Therapeutics
GOG Foundation

Completed

A Study of VB-111 With Paclitaxel vs Paclitaxel for Treatment of Recurrent Platinum-Resistant Ovarian Cancer (OVAL) (OVAL)

Recurrent Platinum Resistant Ovarian Cancer

United States, Israel, Japan, Poland, Spain
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd; Nektar Therapeutics

Completed

An Investigational Study of NKTR-214 Combined With Nivolumab in Japanese Participants With Advanced Solid Tumors

Advanced Cancer

Japan
iCell Gene Therapeutics
Peking University Shenzhen Hospital; iCAR Bio Therapeutics Ltd.; Chengdu Military...

Unknown

CD20-CD19 Compound CAR (cCAR) T Cells for Patients With Relapsed /Refractory B Cell Malignancies

B Cell Lymphoma | B Cell Leukemia

China
iCell Gene Therapeutics
Peking University Shenzhen Hospital; iCAR Bio Therapeutics Ltd.; Chengdu Military...

Unknown

CD19 CARvac T Cells for Patients With Relapsed / Refractory B Cell Malignancies

B Cell Lymphoma | B Cell Leukemia

China
iCell Gene Therapeutics
Peking University Shenzhen Hospital; iCAR Bio Therapeutics Ltd.; Chengdu Military...

Unknown

CD123-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myeloid Leukemia | Hematologic Malignancy | Myeloproliferative Neoplasm

China
iCell Gene Therapeutics
Peking University Shenzhen Hospital; iCAR Bio Therapeutics Ltd.; Chengdu Military...

Unknown

BCMA-CS1 Compound CAR (cCAR) T Cells for Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

China
Musli Thyropeutics Ltd.
Tel-Aviv Sourasky Medical Center

Terminated

Study of Induction of Hypothyroxinemia Adjunct to Conventional Therapies in GBM Patients

Glioblastoma Multiforme (GBM)

Israel
Lambda Therapeutic Research Ltd.
Intas Pharmaceutical Limited (Biopharma Division)

Recruiting

Denosumab Biosimilar Injection in Post Menopausal Women With Osteoporosis

Osteoporosis, Postmenopausal

India
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Combination With Standard First-line Treatment in Subjects With Advanced Digestive System Neoplasms

Digestive System Neoplasms

China
HuidaGene Therapeutics Co., Ltd.
Eye & ENT Hospital of Fudan University

Not yet recruiting

a Study in Subjects With Otoferlin Mutation-related Hearing Loss Using RNA Base-eDiting Therapy(SOUND) (SOUND)

Congenital Hearing Loss

China
Centessa Pharmaceuticals (UK) Limited
LockBody Therapeutics Ltd

Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of LB101 in Participants With Advanced Solid Tumors

Advanced Solid Tumor

United States, France
The First Affiliated Hospital of Soochow University
Fundamenta Therapeutics, Ltd.

Recruiting

ThisCART19A Bridging to alloHSCT for R/R B-ALL

CAR | Refractory Acute Lymphoblastic Leukemia | Relapsed Adult ALL

China
Fundamenta Therapeutics, Ltd.
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Safety and Clinical Activity of ThisCART19 in Patients With r/r Non-Hodgkin's B Cell Lymphoma

B-cell Malignancy

China
Fundamenta Therapeutics, Ltd.
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Safety and Clinical Activity of ThisCART22 in Patients With r/r Non-Hodgkin's B Cell Lymphoma

B-cell Malignancy

China
AlaMab Therapeutics (Shanghai) Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of ALMB-0168 in Patients With Osteosarcoma

Osteosarcoma
Shanxi Province Cancer Hospital
Novatim Immune Therapeutics (Zhejiang) Co., Ltd.

Recruiting

Targeting CD19 and BCMA CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

China
Kinoxis Therapeutics Pty Ltd
National Institute on Drug Abuse (NIDA)

Completed

A Phase 1 Study Investigating the Safety, Tolerability and Pharmacokinetics of KNX100 in Healthy Volunteers (KTX101)

Opioid-use Disorder | Healthy Volunteer Study

Australia
Horizon Therapeutics Ireland DAC

Completed

Study to Evaluate HZN-457 in Healthy Volunteers

Healthy

New Zealand
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Active, not recruiting

Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Malignant Tumor

Advanced Malignant Solid Tumor

China
Shanghai PerHum Therapeutics Co., Ltd.
Shanghai Public Health Clinical Center

Active, not recruiting

Safety and Efficacy of CCT301 CAR-T in Adult Subjects With Recurrent or Refractory Stage IV Renal Cell Carcinoma

Renal Cell Carcinoma

China
Rong Tao
Novatim Immune Therapeutics (Zhejiang) Co., Ltd.

Recruiting

CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL

Acute Lymphoblastic Leukemia, in Relapse | B-cell Lymphoma Refractory | B-cell Lymphoma Recurrent | Acute Lymphoblastic Leukemia With Failed Remission

China
China Medical University, China
Shanghai First Song Therapeutics Co., Ltd

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of Anti-HER2-CAR-T Cells Injection in Patients With Solid Tumors

Solid Tumor

China

Clinical Trials Sponsored by Factor Therapeutics Ltd.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Switzerland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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