Clinical Trials Sponsored by Janssen Biotech, Inc.

Total 493 results

The Crofoot Research Center, Inc.
Janssen Scientific Affairs, LLC

Completed

Rapid Reinitiation of a Single Tablet Antiretroviral Therapy Using Symtuza® in HIV-1 Infected Treatment-Experienced Patients Off Therapy. (ReSTART) (ReSTART)

HIV-1-infection

United States
M.D. Anderson Cancer Center
Medivation, Inc.; Janssen Services, LLC

Completed

Abiraterone Acetate Plus LHRH Agonist and Abiraterone Acetate Plus LHRH Agonist and Enzalutamide

Prostate Cancer

United States
University of Alabama at Birmingham
Miltenyi Biotec, Inc.

Active, not recruiting

Standardization of CD3+ T Cell Dose for Patients Receiving Allogeneic Peripheral Blood Stem Cell Transplantation From Matched Related Donors

Hematopoietic Stem Cell Transplantation

United States
Joanne Kurtzberg, MD
Duke University; Miltenyi Biotec, Inc.

Available

Expanded Access to T-cell Depleted Haplo-Identical Stem Cells for Patients Receiving Haplo-Identical and Unrelated Cord Blood Transplants

Hematologic Malignancies | Immune Deficiencies | Inborn Errors of Metabolism Disorders

United States
Duke University
Genentech, Inc.; Daiichi Sankyo, Inc.; American Heart Association; Janssen, LP

Completed

Addressing Real-world Anticoagulant Management Issues in Stroke (ARAMIS)

Stroke | Intracerebral Hemorrhage | Cerebrovascular Stroke

United States
Hackensack Meridian Health
Janssen Scientific Affairs, LLC; Genentech, Inc.

Active, not recruiting

A Study of ABT-199 Plus Ibrutinib and Rituximab in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Refractory Diffuse Large B-Cell Lymphoma | Relapsed Diffuse Large B-Cell Lymphoma

United States
Janssen-Ortho Inc., Canada
Ontario Clinical Oncology Group (OCOG)

Completed

Impact of Erythropoietin Treatment Versus Placebo on Quality-of-life in Patients With Advanced Prostate Cancer.

Carcinoma | Prostate
M.D. Anderson Cancer Center
BioTex, Inc.

Completed

Correlation of MR Thermal Imaging to Actual Size of Ablation During Laser Ablation Therapy

Bone Metastases | Advanced Cancer

United States
M.D. Anderson Cancer Center
BioTex, Inc.

Terminated

Magnetic Resonance Temperature Imaging & Imaging-Guided Laser Induced Thermal Therapy for Treatment of Metastatic Brain Tumors

Brain Tumor

United States
H. Lee Moffitt Cancer Center and Research Institute
Millennium Pharmaceuticals, Inc.; Ortho Biotech, Inc.

Completed

Cyclophosphamide, VELCADE, DOXIL, and Dexamethasone, (CVDD) in Newly Diagnosed Patients With Multiple Myeloma (MM)

Multiple Myeloma

United States
Jonsson Comprehensive Cancer Center
Genentech, Inc.

Completed

Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States
Jonsson Comprehensive Cancer Center
Viewray Inc.

Active, not recruiting

Stereotactic Body Radiation Therapy in Treating Patients With Localized Prostate Cancer That Have Undergone Surgery

PSA Progression | Stage III Prostate Adenocarcinoma AJCC v7 | Stage II Prostate Adenocarcinoma AJCC v7 | PSA Level Greater Than 0.03 | Stage I Prostate Adenocarcinoma AJCC (American Joint Committee on Cancer ) v7

United States
Jonsson Comprehensive Cancer Center
ImaginAb, Inc.

Completed

Phase I Study to evaluate124I-A11 PSCA Minibody in Patients With Metastatic Prostate, Bladder and Pancreatic Cancer

Pancreatic Cancer | Prostate Cancer | Bladder Cancer

United States
Taipei Medical University Hospital
Taipei Medical University; Panion & BF Biotech Inc.

Recruiting

Polymeric Microspheres vs Sculptra® in the Treatment of Moderate to Severe Nasolabial Folds

Nasolabial Fold Wrinkles

Taiwan
Sidney Kimmel Comprehensive Cancer Center at Johns...
PapiVax Biotech, Inc.

Recruiting

Safety and Efficacy of Allogeneic HPV-specific T Cells in Adults With Recurrent or Metastatic HPV16+ Cancers

HPV 16+ Recurrent or Metastatic Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Ortho Biotech, Inc.

Completed

Rituximab and Combination Chemotherapy in Treating Older Patients With Diffuse Large B-Cell Lymphoma

Lymphoma

United States
University Health Network, Toronto
Princess Margaret Hospital, Canada; Ortho Biotech, Inc.

Completed

Combination Bortezomib-containing Regimens in Newly Diagnosed Patients With t (4; 14) Positive Multiple Myeloma

Multiple Myeloma

Canada
Jonsson Comprehensive Cancer Center
Genentech, Inc.

Completed

Trastuzumab and Erlotinib as First-Line Therapy in Treating Women With Metastatic Breast Cancer Associated With HER2/Neu Overexpression

Breast Cancer

United States
Jonsson Comprehensive Cancer Center
Genentech, Inc.

Completed

Rituximab in Treating Patients With Waldenstrom's Macroglobulinemia

Lymphoma

United States, Canada
Jonsson Comprehensive Cancer Center
NantCell, Inc.

No longer available

Single Patient Expanded Access to Ganitumab for Metastatic Ewing Sarcoma

Ewing Sarcoma
The Third Xiangya Hospital of Central South University
SANSURE BIOTECH INC.

Unknown

Multicenter Study on Detection Strategy of Infectious Diseases in Blood Transfusion

Infectious Disease Screening

China
Bristol-Myers Squibb
Novartis; Clovis Oncology, Inc.; Janssen Pharmaceuticals; Exelixis

Recruiting

Pan Tumor Rollover Study

Cancer

United States, Israel, Spain, Italy, Germany, Australia, Belgium, China, Korea, Republic of, Greece, Japan, Argentina, Austria, Brazil, Canada, Chile, Denmark, Finland, France, Hungary, Ireland, Mexico, Netherlands, Poland, Russian Federation and more
Associated Scientists to Help Minimize Allergies
Eisai Inc.; Janssen Pharmaceuticals

Completed

Evaluate the Effects on Asthma Control of Rabeprazole Given Twice Daily in Subjects With Asthma.

Asthma | Gastroesophageal Reflux Disease

United States
University of British Columbia
University Health Network, Toronto; Janssen Inc.

Recruiting

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer (GUNS)

Prostate Cancer

Canada, United States
Scripps Translational Science Institute
Janssen Scientific Affairs, LLC; Aetna, Inc.

Completed

mHealth Screening to Prevent Strokes (mSToPS)

Atrial Fibrillation

United States
McMaster University
Hamilton Health Sciences Corporation; Janssen-Ortho Inc., Canada

Terminated

Efficacy of Adding Topiramate to Current Treatment in Treatment-Resistant Generalized Social Phobia (GSP)

Social Phobia

Canada
McMaster University
Hamilton Health Sciences Corporation; Janssen-Ortho Inc., Canada

Completed

Efficacy of Adding Topiramate to Current Treatment in Refractory Obsessive Compulsive Disorder (OCD)

Obsessive Compulsive Disorder

Canada
University of Cologne
Pfizer; F2G Biotech GmbH; Basilea Pharmaceutica; Cidara Therapeutics Inc.; Matinas...

Recruiting

FungiScope - A Global Emerging Fungal Infection Registry (FungiScope)

Invasive Fungal Disease

Germany
Scott C. Woller, MD
Janssen Pharmaceuticals

Not yet recruiting

Alerting Providers at Patient Hospital Discharge to Consider Prescribing Rivaroxaban to Reduce Venous Thromboembolism (eVTE)

Deep Vein Thrombosis | Hospitalism | Venous Thromboembolic Disease | Pulmonary Embolism and Thrombosis

United States
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

Changes in Triglyceride and Other Lipids (Levels of Fats Found in Blood) When Taking Darunavir Compared to Atazanavir in HIV-infected Patients That Have Never Received Treatment

HIV

United States
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

GRACE: A Study to Compare the Effectiveness, Safety and Tolerability of PREZISTA (Darunavir)/Ritonavir by Gender and Race When Administered With Other Antiretroviral Medications in Human Immunodeficiency Virus (HIV) Positive Women and Men.

HIV | Infectious

United States, Canada, Puerto Rico
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

A Study of the Once Daily Combination of Etravirine and Darunavir/Ritonavir As Dual Therapy in Early Treatment-Experienced Patients (INROADS)

Human Immunodeficiency Virus (HIV)

United States, Puerto Rico
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

A Phase I, Open-label Trial to Explore the Pharmacokinetics, Safety and Tolerability of TMC278 (Rilpivirine) 25 mg Once Daily Following a 2-week Period Receiving Efavirenz, in Healthy Male and Female Volunteers

HIV
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

Enfuvirtide/Current Protease Inhibitor Switch to PREZISTA (Darunavir)/Ritonavir + TMC125 in HIV Patients With Enfuvirtide Side Effects.

HIV

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Celgene; Aduro Biotech, Inc.

Active, not recruiting

Allogeneic Myeloma GM-CSF Vaccine With Lenalidomide in Multiple Myeloma Patients in Complete or Near Complete Remission

Multiple Myeloma

United States
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

A Study to Evaluate the Pharmacokinetic Profile (How the Body Absorbs, Distributes, Metabolizes and Eliminates a Drug) of TMC125 Plus Tenofovir/Emtricitabine Once Daily With or Without Darunavir/r Once Daily in Antiretroviral (ARV) Naive HIV-1 Patients (Patients Have Never Received ARV Treatment).

HIV-1 Infection
Jonsson Comprehensive Cancer Center
Novartis; Seagen Inc.

Recruiting

Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC... and other conditions

United States
Jonsson Comprehensive Cancer Center
Kate Farms Inc

Recruiting

Pea Protein Oral Nutrition Supplement for the Reduction of Gastrostomy Tube Placement Rate in Patients With Locally Advanced Head and Neck Cancer Undergoing Chemoradiation Therapy

Locally Advanced Head and Neck Carcinoma

United States
Jonsson Comprehensive Cancer Center
eHealth International, INC.

Recruiting

A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

Obesity | Malignant Neoplasm

United States
Jonsson Comprehensive Cancer Center
Stemline Therapeutics, Inc.

Withdrawn

Tagraxofusp to Eradicate Measurable Residual Disease in Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
Jonsson Comprehensive Cancer Center
Arcus Biosciences, Inc.

Suspended

Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Borderline Resectable Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma

United States
Jonsson Comprehensive Cancer Center
Millennium Pharmaceuticals, Inc.

Completed

Bortezomib, Temozolomide, and Regional Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Brain and Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center
Progenics Pharmaceuticals, Inc.

Terminated

Randomized Trial of PSMA PET Scan Before Definitive Radiation Therapy for Prostate Cancer (PSMA-dRT)

Stage II Prostate Cancer AJCC v8 | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IIA Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer AJCC v8 | Stage I Prostate...

United States
Jonsson Comprehensive Cancer Center
Millennium Pharmaceuticals, Inc.

Completed

Adjuvant Bortezomib Maintenance Therapy After Autologous Peripheral Stem Cell Transplantation in Treating Patients With Intermediate or Advanced Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
Jonsson Comprehensive Cancer Center
Millennium Pharmaceuticals, Inc.

Completed

Bortezomib in Treating Patients With Relapsed or Refractory Cutaneous T-Cell Lymphoma

Lymphoma

United States
Children's Hospital of Orange County
KitoTech Medical, Inc.

Recruiting

Comparison of microMend® Devices to Sutures in Closing Lacerations in Children

Wound Heal | Laceration | Skin Wound

United States
DFB Soria, LLC
Bioskin GmbH; US Biotest, Inc.

Completed

Trial to Assess the Potency of SOR007 Ointment in a Psoriasis Plaque Test

Plaque Psoriasis

United States
International Myeloma Foundation
Janssen Scientific Affairs, LLC; Celgene; Amgen; Trevie, Inc.

Active, not recruiting

Aggressive Smoldering Curative Approach Evaluating Novel Therapies and Transplant (ASCENT)

Smoldering Multiple Myeloma

United States
Isabelle Fortin
Janssen Inc.

Completed

Assessment of Tender & Swollen Joints Count Score Performed by a Rheumatologist And Rheumatology Nurses in Patients With RA and PsA. (APRAN)

Rheumatoid Arthritis | Psoriatic Arthritis

Canada
US Biotest, Inc.
United States Department of Defense

Completed

Study of the Safety of USB005 in Healthy Volunteers

Healthy Volunteers

United States

Clinical Trials Sponsored by Janssen Biotech, Inc.

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