Clinical Trials Sponsored by Leicester Royal Infirmary NHS Trust

Total 962 results

Guy's and St Thomas' NHS Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Optimisation of Mechanical Insufflation:Exsufflation (MIE2)

Neuromuscular Diseases

United Kingdom
Oxford University Hospitals NHS Trust
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust

Completed

Benefit of CFAE Ablation (BOCA)

Persistent Atrial Fibrillation

United Kingdom
Brunel University
Royal Free Hospital NHS Foundation Trust

Recruiting

A Co-designed Physical Activity Intervention in Fabry Disease

Fabry Disease

United Kingdom
The Royal Wolverhampton Hospitals NHS Trust
Gebauer Company

Recruiting

Investigator Initiated, Prospective Study of Xenia Corneal Lenticule

Keratoconus | Post-Laser Retinal Condition

United Kingdom
Royal Marsden NHS Foundation Trust
Bristol-Myers Squibb

Active, not recruiting

SBRT With Immunotherapy in Early Stage Non-small Cell Lung Cancer: Tolerability and Lung Effects (STILE)

Non-small Cell Lung Cancer Stage I | Non-small Cell Lung Cancer Stage II

United Kingdom
Heartfelt Technologies
Royal Brompton & Harefield NHS Foundation Trust

Completed

Feasibility Study of a New Peripheral Oedema Monitor for Heart Failure

Heart Failure, Diastolic | Edema Brain | Decompensated Heartfailure

United Kingdom
Royal Free Hospital NHS Foundation Trust
Innovate UK

Active, not recruiting

CirrhoCare in COVID-19: A Pilot, Remote, Home Monitoring Study in Advanced Cirrhosis

Decompensated Cirrhosis

United Kingdom
Wuerzburg University Hospital
Royal Marsden NHS Foundation Trust

Completed

Fractionated Radiosurgery for Painful Spinal Metastases (DOSIS)

Pain | Neoplasm Metastasis | Neoplastic Processes | Neoplasm, Residual | Neoplasm Recurrence, Local

Switzerland, Netherlands, Germany, United Kingdom
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Unknown

Molecular, Pathologic and MRI Investigation of the Prognostic and Redictive Importance of Extramural Venous Invasion in Rectal Cancer (MARVEL) Trial (MARVEL)

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Gastrointestinal Neoplasms | Digestive System Neoplasms | Intestinal Diseases | Colorectal Neoplasms | Intestinal Neoplasms | Rectal... and other conditions

United Kingdom
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Unknown

Mri IN STaging REctal Polyp Planes (MINSTREL)

Rectal Cancer | Rectal Neoplasms | Colonic Polyps

United Kingdom
Royal Marsden NHS Foundation Trust
University of Warwick

Unknown

Using an Electronic Nose to Predict Gastrointestinal Consequences of Pelvic Radiotherapy (PREDICT)

Cancer | Toxicity | Malignancy

United Kingdom
Royal Marsden NHS Foundation Trust
Hoffmann-La Roche

Terminated

R-CHOP-B Bevacizumab for Diffuse Large B Cell Lymphoma

B-cell Lymphoma | Non-Hodgkin's Lymphoma

United Kingdom
Royal Free Hampstead NHS Trust
Roche Pharma AG

Completed

Lopinavir Capsules to Kaletra or Invirase Tablets (LoCKIT)

HIV Infections

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Mid and South Essex NHS Foundation... and other collaborators

Not yet recruiting

Multivessel Balloon Occlusion to Investigate Obstructive Coronary Artery Disease and aNgina (ORBITA-MOON)

Stable Angina | Multivessel Coronary Artery Disease

United Kingdom
Royal Berkshire NHS Foundation Trust
University of Reading

Recruiting

Prebiotics in Reducing Inflammation and Clinical Endpoints in Ulcerative Colitis (PRInCE-UC) (PRInCE-UC)

Ulcerative Colitis

United Kingdom
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Not yet recruiting

Pre-therapeutic MRI Assessment of Early Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery: A New Approach to the Management of Early Stage Rectal Cancer. (PRESERVE)

Rectal Cancer

United Kingdom
Royal Free Hospital NHS Foundation Trust
Roche Diagnostics

Completed

SARS-CoV-2 (COVID-19) Antibody PrevalencE in an Adult London HIV Cohort (SCAPE-HIV)

Covid19 | SARS-CoV Infection | HIV-1-infection

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Aalborg University

Completed

Metabolic Cost of IMT

Mechanical Ventilation Complication

United Kingdom
University of Reading
Royal Berkshire NHS Foundation Trust

Withdrawn

Zinc and Post-Operative Cognitive Dysfunction

Cognitive Dysfunction

United Kingdom
Oxehealth Limited
Royal Brompton & Harefield NHS Foundation Trust

Completed

Analysis of Vital Signs in Patients With COVID-19

Respiratory Disease

United Kingdom
Iva Hauptmannova

Terminated

Extramembranous and Interosseous Technique of Tibialis Posterior Tendon Transfer

Cerebral Palsy | Poliomyelitis | Nerve Injury | Leprosy | Muscle Injury

United Kingdom
Acurable Ltd.
Royal Free Hospital NHS Foundation Trust

Completed

Clinical Evaluation of a Wearable Sleep Diagnosis Technology

Obstructive Sleep Apnea

United Kingdom
Royal Holloway University
Barts & The London NHS Trust

Unknown

CFT Self-Help for Accessing Cervical Screening After Sexual Assault

Cervical Cancer | Sexual Violence | Trauma, Psychological
Royal Brompton & Harefield NHS Foundation Trust
Acutus Medical

Unknown

HCM-AF Ablation With ACUTUS

Atrial Fibrillation | Hypertrophic Cardiomyopathy
The Royal Wolverhampton Hospitals NHS Trust
Sysmex Medical

Completed

The Efficacy of Sentimag in Detection of Sentinel Node Biopsy (SMART)

Breast Cancer | Sentinel Node

United Kingdom
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Unknown

Low Rectal Cancer Study (MERCURY II) (MERCURY II)

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Gastrointestinal Neoplasms | Digestive System Neoplasms | Intestinal Diseases | Colorectal Neoplasms | Intestinal Neoplasms | Rectal... and other conditions

United Kingdom, Germany, Serbia
Royal Marsden NHS Foundation Trust
Cancer Research UK

Unknown

CHOP vs GEM-P in 1st Line Treatment of T-cell Lymphoma, Multicentre Phase II Study (CHEMO-T)

Angioimmunoblastic T-cell Lymphoma | Enteropathy-Associated T-Cell Lymphoma | Anaplastic Large Cell Lymphoma, ALK-Negative | Peripheral T-cell Lymphoma NOS | Hepatosplenic Gamma/ Delta T-cell Lymphoma

United Kingdom
Royal Marsden NHS Foundation Trust
University of Surrey

Completed

A Survivorship Care Plan for Gynaecological Cancer Patients

Sarcoma | Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United Kingdom
The Royal Wolverhampton Hospitals NHS Trust
Maquet Cardiovascular

Completed

MACCE After Endoscopic Vein Harvest for CABG (MAQEH)

Complications Due to Coronary Artery Bypass Graft

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London

Completed

Chemotherapy Induced Painful Peripheral Neuropathy Ethosuximide (The CIN-E Study) (CINE-E)

Cancer | Peripheral Neuropathy

United Kingdom
Royal Marsden NHS Foundation Trust
Roche Pharma AG

Completed

Capecitabine and Oxaliplatin Plus Bevacizumab as Neoadjuvant Treatment for Untreated Unresectable Liver-only Metastases From Colorectal Cancer

Metastatic Colorectal Cancer

United Kingdom
University of Surrey
Royal Marsden NHS Foundation Trust

Completed

Body Image Issues in Boys Being Treated at the Royal Marsden

Cancer

United Kingdom
Ourotech, Inc.
Royal Free Hospital NHS Foundation Trust; Imperial College Healthcare NHS Trust and other collaborators

Not yet recruiting

Prospective Evaluation of AI R&D Tool for Patient Stratification: a Trial for Renal Immuno-oncology Model Experimental Evaluation 2 (PEAR-TREE2)

Kidney Cancer | Renal Cell Cancer Metastatic

United Kingdom
Royal Free Hospital NHS Foundation Trust
Acurable Ltd.

Recruiting

AcuPebble to Remotely Monitor Patients With OSA on CPAP Therapy

Sleep Apnea, Obstructive

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London

Not yet recruiting

IMaC - Immune Pathways in Oesophagogastric Cancer (IMaC)

Oesophagogastric Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
University of Leeds

Recruiting

EVEREST-HN 1: EVolution of a patiEnt-REported Symptom-based Risk Stratification sySTem

Head and Neck Cancer

United Kingdom
Bispebjerg Hospital
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

A Comprehensive Evaluation of the Impact of ATP on Laryngeal Symptoms, Hypersensitivity and Function (MISP COUGH)

Chronic Refractory Cough

Denmark
The Royal Orthopaedic Hospital NHS Trust
Stryker Nordic

Recruiting

A Comparison of Impingement Free Range of Motion With CT Scan After Manual and Robotic Total Hip Replacement

Post-traumatic Osteoarthritis | Inflammatory Arthritis | Hip Osteoarthritis | Avascular Necrosis of Hip | Congenital Hip Problems

United Kingdom
Marianna Fontana

Recruiting

Exploration of Arrhythmia Burden in Cardiac Amyloidosis Using Implantable Loop Recorders (EXACLIBUR)

Sudden Cardiac Death | Arrythmia | Cardiac Amyloidosis | Systemic AL Amyloidosis

United Kingdom
Royal Marsden NHS Foundation Trust
Ventana Medical Systems

Recruiting

Value of Analysing Under-utilised Leftover Tissue (VauLT) (VauLT)

Oncology

United Kingdom
Royal Marsden NHS Foundation Trust
Francis Crick Institute

Recruiting

TRACERx Renal CAPTURE Sub-study (TRACERxRenal)

Renal Cell Carcinoma | Cancer | Healthy Volunteers

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London

Active, not recruiting

Changes to Function and Quality of Life and Patient Experience for Patients Undergoing Treatments for Recurrent Oropharyngeal Cancer (FUNQOLR)

Recurrent Oropharynx Carcinoma

United Kingdom
University of Reading
Royal Berkshire NHS Foundation Trust

Active, not recruiting

Supporting Cardiac Rehabilitation With eNutriCardio

Diet Modification | Diet Habit | Cardiac Event

United Kingdom
Royal Marsden NHS Foundation Trust
Boehringer Ingelheim; Celgene

Withdrawn

Combination Nab-paclitaxel (N-P) and Nintedanib or N-P and Placebo in Relapsed NSCLC Adenocarcinoma (N3)

Adenocarcinoma of Lung | NSCLC, Recurrent
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Completed

Surgical Anatomy and 'Waisting' of the sIgmoid SpEcimen (WISE)

Sigmoid, Sigmoid Colon, Neoplasm, Cancer

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Olympus Corporation

Completed

EBUS-TBNA vs Flex 19G EBUS-TBNA

Lymphoma | Lung Cancer | Lymphadenopathy | Sarcoidosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Imperial College London and other collaborators

Active, not recruiting

Validation of an Artificial Intelligence Enabled Diagnostic Support Software (ArtiQ.Spiro) in Primary Care Spirometry Datasets - a Retrospective Analysis

Respiratory Disease

United Kingdom
University of Birmingham
Royal Marsden NHS Foundation Trust; The Leeds Teaching Hospitals NHS Trust; Guy... and other collaborators

Active, not recruiting

Measuring the Quality of Surgical Care and Setting Benchmarks for Training Using Intuitive Data Recorder Technology (MASTERY)

Cancer | Surgery

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Mid and South Essex NHS Foundation... and other collaborators

Recruiting

Finding the Invasive Haemodynamic Threshold for Symptom Relief in Stable Angina (ORBITA-FIRE)

Stable Angina

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Not yet recruiting

Haemodynamics of Mitral Regurgitation Reduction (STRESS-MR)

Mitral Regurgitation

Clinical Trials Sponsored by Leicester Royal Infirmary NHS Trust

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