Clinical Trials Sponsored by Royal National Orthopaedic Hospital NHS Trust

Total 623 results

King's College Hospital NHS Trust
King's College London; University College London Hospitals; University of Sheffield and other collaborators

Recruiting

RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell Disease (REDRESS)

Sickle Cell Disease

United Kingdom
Queen's University, Belfast
Medical Research Council; Belfast Health and Social Care Trust; NHS Lothian; University... and other collaborators

Completed

Clinimetric Properties of Outcome Measures in Bronchiectasis in the UK

Bronchiectasis

United Kingdom
Oxford University Hospitals NHS Trust

Unknown

Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants

Myelodysplastic Syndromes | Leukemia

United Kingdom
Oxford University Hospitals NHS Trust

Unknown

Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural Effusion

Metastatic Cancer

United Kingdom
University of Leeds
University College London Hospitals; The Leeds Teaching Hospitals NHS Trust; Sheffield... and other collaborators

Completed

TReatment of Irritable Bowel Syndrome With Diarrhoea Using Titrated ONdansetron Trial (TRITON)

IBS - Irritable Bowel Syndrome

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
National Osteoporosis Society

Completed

Change in Free 25(OH)D After High Dose in Vitamin D Deficient Postmenopausal Women

Vitamin D Deficiency | Osteoporosis

United Kingdom
Grace Ward
Guy's and St Thomas' NHS Foundation Trust; Royal Berkshire Hospital

Unknown

The Ecological Role of Yeasts in the Human Gut (YIG)

Irritable Bowel Syndrome | Inflammatory Bowel Diseases | Gastrointestinal Disease

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
King's College London; Cardiff University; University College, London; Newcastle... and other collaborators

Recruiting

Quality-Assured Follow-up of Quiescent Neovascular Age -Related maculaR dEgeneration by Non-medical Practitioners (FENETRE)

AMD

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; National Institute for Health...

Completed

Intelligent Oxygen Therapy During Activities of Daily Living

Hypoxia | COPD | Hyperoxia

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University of Oxford; National Institute for Health Research, United Kingdom

Completed

The POSA Trial - Positional Therapy for Positional OSA (POSA)

Sleep Apnea, Obstructive | Positional Sleep Apnea

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University of Bristol; National Institute for Health Research, United Kingdom

Unknown

Mesothelioma and Radical Surgery 2 (MARS2)

Mesothelioma

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
Novartis Pharmaceuticals; National Institute for Health Research, United Kingdom

Completed

The Vascular Effects of Vildagliptin in Insulin Resistant Individuals

Insulin Resistance | Microvascular Disease

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Rigshospitalet, Denmark; Birmingham Women's and Children's NHS Foundation Trust and other collaborators

Unknown

Effect of Insulin Sensitization on IGF-1 Response to Growth Hormone in SGA Children

Small for Gestational Age
Royal Marsden NHS Foundation Trust
Institute of Cancer Research, United Kingdom; National Health Service, United...

Active, not recruiting

Conventional Care Versus Radioablation (Stereotactic Body Radiotherapy) for Extracranial Oligometastases (CORE)

Breast Cancer | Carcinoma, Non-Small-Cell Lung | Prostate Cancer

United Kingdom, Australia
National Health Service, United Kingdom
Ferring Pharmaceuticals; Hull University Teaching Hospitals NHS Trust; North... and other collaborators

Completed

Probiotics for the Prevention of Antibiotics Associated Diarrhoea and Clostridium Difficile Associated Diarrhoea

Diarrhoea

United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC; National Institute for Health Research, United Kingdom

Terminated

A Study of Pembrolizumab And Platinum With Radiotherapy in Cervix Cancer (PAPAYA)

Cervix Cancer

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Monash University; Australian and New Zealand Intensive Care Research Centre; Royal Surrey County Hospital NHS Foundation Trust

Recruiting

Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome (ACES)

COVID | Acute Respiratory Distress Syndrome

United Kingdom
University Hospital Southampton NHS Foundation...

Completed

Capecitabine or Observation After Surgery in Treating Patients With Biliary Tract Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United Kingdom
University Hospital Southampton NHS Foundation...

Unknown

Follow-Up Study of Patients Who Have Undergone Surgery for Stage I, Stage II, or Stage III Colorectal Cancer

Colorectal Cancer

United Kingdom
Royal College of Surgeons, Ireland
The Hospital for Sick Children; Massachusetts General Hospital; Belfast Health... and other collaborators

Not yet recruiting

ENHANCE- Establishing Natural History in an Advanced New CF Care Era

Cystic Fibrosis
Kingston University
National Institute for Health Research, United Kingdom; St George's University... and other collaborators

Recruiting

Non-medical Practitioner Workforce in the Urgent and Emergency Care System Skill-mix in England (SKILLmix-ED)

Emergencies

United Kingdom
University of Oxford
London School of Hygiene and Tropical Medicine; The Leeds Teaching Hospitals... and other collaborators

Completed

Temporal Artery Biopsy vs ULtrasound in Diagnosis of GCA (TABUL) (TABUL)

Giant Cell Arteritis

Ireland, United Kingdom, Germany, Norway, Portugal
University Hospital Southampton NHS Foundation...

Unknown

Combination Chemotherapy and Rituximab in Treating Patients With Primary Mediastinal Diffuse Large B-Cell Lymphoma

Lymphoma

United Kingdom
Belfast Health and Social Care Trust
Bristol Royal Infirmary; Royal Infirmary of Edinburgh; Golden Jubilee National...

Unknown

DISsection RE-entry Evaluation With Absorb Bioresorbable Vascular Scaffolds in CTO. (DISCRETE-CTO)

Coronary Artery Disease

United Kingdom
Queen Mary University of London
King's College London; University College London Hospitals; Barts & The London... and other collaborators

Recruiting

Mechanism of Chronic Pain in Patients With IBD

Inflammatory Bowel Diseases

United Kingdom
Royal Marsden NHS Foundation Trust
King's College London; University College, London; Institute of Cancer Research... and other collaborators

Recruiting

A Study Comparing Urolift and TURP Ahead of Radiotherapy in Men With Urinary Symptoms Secondary to Prostate Enlargement (CO-STAR)

Prostate Cancer

United Kingdom
Birmingham Women's and Children's NHS Foundation...
University of Sheffield; Royal Manchester Children' s Hospital, Manchester

Completed

Whole Body Vibration Training in Children With Osteogenesis Imperfecta and Limited Mobility

Osteogenesis Imperfecta

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Symptom Control With or Without Docetaxel in Treating Patients With Relapsed Esophageal Cancer or Stomach Cancer

Pain | Gastric Cancer | Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction | Nausea and Vomiting

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors

Testicular Germ Cell Tumor | Teratoma | Extragonadal Germ Cell Tumor

United Kingdom
Gateshead Health NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; National Institute for Health Research...

Unknown

Vascular Augmentation of Late-life Unremitted Depression (VALUeD) (VALUeD)

Depression

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Capecitabine and Streptozocin With or Without Cisplatin in Treating Patients With Unresectable or Metastatic Neuroendocrine Tumors

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Vatalanib in Treating Patients With Metastatic Cutaneous Melanoma That Cannot be Removed by Surgery

Melanoma (Skin)

United Kingdom
Hull University Teaching Hospitals NHS Trust

Completed

Gemcitabine With or Without Dalteparin in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Pancreatic Cancer | Thromboembolism

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Unknown

Neoadjuvant Epirubicin, Cyclophosphamide, and Paclitaxel With or Without Gemcitabine in Treating Women Who Are Undergoing Surgery for Early Breast Cancer

Breast Cancer

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Unknown

Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine for Advanced Colorectal Cancer or Breast Cancer

Breast Cancer | Colorectal Cancer | Palmar-plantar Erythrodysesthesia

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Unknown

Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Nonmetastatic Breast Cancer

Breast Cancer | Perioperative/Postoperative Complications | Cardiac Toxicity

United Kingdom
King's College Hospital NHS Trust
European Society of Intensive Care Medicine; Royal Centre for Defence Medicine

Not yet recruiting

The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock (REPERFUSE)

Septic Shock | Acute Kidney Injury

United Kingdom
University Hospitals of Derby and Burton NHS Foundation...
University of Nottingham; Northern Care Alliance NHS Foundation Trust; University... and other collaborators

Recruiting

Application of Functional Renal MRI to Improve Assessment of Chronic Kidney Disease (AFiRM)

Chronic Kidney Diseases

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust
Minimal Access Therapy Training Unit; GUTS - Fighting Bowel Cancer

Recruiting

FIT in Diverticulitis

Colorectal Cancer | Diverticulitis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Imperial College London; British Lung Foundation; National Heart and Lung Institute

Completed

The Use of Inflammatory Markers to Guide Therapy in Children With Severe Asthma

Asthma

United Kingdom
Nottingham University Hospitals NHS Trust
Wellcome Trust; National Institute for Health Research, United Kingdom

Unknown

The Use of Interactive Binocular Treatment (I-BiT) for the Management of Anisometropic, Strabismic and Mixed Amblyopia in Children Aged 3.5 - 12 Years (I-BiT Plus)

Strabismus | Amblyopia
Royal Devon and Exeter NHS Foundation Trust
National Institute for Health Research, United Kingdom; University of Exeter

Completed

Predicting Response to Incretin Based Agents in Type 2 Diabetes (PRIBA)

Type2 Diabetes

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Institute for Health Research: CLAHRC YH; The... and other collaborators

Completed

Use of the SMART COPD Physical Activity App in Pulmonary Rehabilitation

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Dr Eoin R Hyde
Royal Free Hospital NHS Foundation Trust; National Institute for Health Research...

Completed

3D Virtual Models as an Adjunct to Preoperative Surgical Planning

Kidney Neoplasms | Surgical Oncology

United Kingdom
NHS National Waiting Times Centre Board
NHS Greater Glasgow and Clyde; University of Glasgow; Royal London Hospital

Not yet recruiting

Incidence, Impact and Mechanisms of Perioperative Right VEntricular Dysfunction (IMPRoVE) (IMPRoVE)

Right Ventricular Dysfunction

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
National Institute for Health Research, United Kingdom; Alder Hey Children's...

Recruiting

Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP) (AIR:RRP)

Human Papilloma Virus | Recurrent Respiratory Papillomatosis

United Kingdom
University of Surrey
European Foundation for the Study of Diabetes; Royal Surrey County Hospital...

Terminated

The Effect of Rimonabant on Energy Expenditure, Fat Metabolism and Body Composition

Obesity

United Kingdom
Nisha Acharya
Children's Hospital of Philadelphia; University of Miami; National Eye Institute... and other collaborators

Active, not recruiting

Adalimumab in JIA-associated Uveitis Stopping Trial (ADJUST)

Uveitis | JIA

United States, Australia, United Kingdom
Liverpool University Hospitals NHS Foundation Trust
The Leeds Teaching Hospitals NHS Trust; National Institute for Health Research... and other collaborators

Completed

Improving Quality of Life Through the Routine Use of the Patient Concerns Inventory for Head and Neck Cancer Patients

Cancer of Head and Neck

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Oxford; National Institute for Health Research, United Kingdom; Oxford University Hospitals NHS Trust

Completed

Continuous vs Intermittent Dabrafenib Plus Trametinib in BRAFV600 Mutant Stage 3 Unresectable or Metastatic Melanoma (INTERIM)

Melanoma

United Kingdom

Clinical Trials Sponsored by Royal National Orthopaedic Hospital NHS Trust

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Trinidad & Tobago

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Rare Diseases

Drug Interventions

Dietary Supplements

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