Search clinical trials for: Blood Transfusion

Total 109786 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Phase II Decitabine (DAC) Versus Azacitidine (AZA) in Myelodysplastic Syndrome (MDS)

Leukemia

United States
University of Texas Southwestern Medical Center

Active, not recruiting

Alteration of Stool Microbiota in Preterm Infants With Anemia

Necrotizing Enterocolitis | Dysbiosis | Anemia, Neonatal

United States
Children's Cancer Hospital Egypt 57357

Completed

Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Will Change in Blood Loss and Transfusion Requirements.

Osteosarcoma | Ewing Sarcoma of Bone

Egypt
Piotr Biega

Completed

Tranexamic Acid After Pathological Fracture Treated With Modular Arthroplasty

Metastases to Bone

Poland
SecuraBio

Completed

A Phase 2 Study Comparing 2 Intermittent Dosing Schedules of Duvelisib in Subjects With Indolent Non-Hodgkin Lymphoma (TEMPO)

Indolent Non-Hodgkin Lymphoma

Korea, Republic of, Czechia, United States, United Kingdom, Italy, Poland, Russian Federation, Germany
Celgene

Completed

The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Due to International Prognostic Scoring System (IPSS) Low Risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome

United States, Australia, Canada, Czechia, France, Germany, Italy, Korea, Republic of, Mexico, Poland, Sweden, United Kingdom, Belgium, Brazil, Denmark, Finland, Greece, Israel, Netherlands, Norway, Portugal, Spain, Turkey
Banc de Sang i Teixits
Sistema d'Emergències Mèdiques (SEM); IDIBGI (Institut d'Investigació Biomèdica...

Completed

Transfusion of Red Blood Cells, Tranexamic Acid and Fibrinogen Concentrate for Severe Trauma Hemorrhage at Pre-hospital Phase of Care. (PRETIC)

Polytrauma | Traumatic Hemorrhage

Spain
Rare Partners srl Impresa Sociale
Università degli Studi di Ferrara

Completed

Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients (SIRTHALACLIN)

Beta-Thalassemia

Italy
Takeda

Active, not recruiting

A Study of TAK-079 in Adults With Persistent/Chronic Primary Immune Thrombocytopenia

Primary Immune Thrombocytopenia

Spain, United States, Croatia, Italy, China, Germany, Bulgaria, Greece, Slovenia, Japan, Ukraine
Population Health Research Institute

Active, not recruiting

Small-Volume Tubes to Reduce Anemia and Transfusion (STRATUS)

Blood Loss Anemia

Canada
Institute of Hematology and Blood Transfusion,...
CZECRIN - Czech Clinical Research Infrastructure Network

Suspended

Ponatinib Plus Reduced-intensity Chemotherapy in the First-line Treatment of Adult Patients With Ph+ ALL (Pona-CELL)

Newly Diagnosed | Acute Lymphoblastic Leukemia, Adult | Ph+ ALL

Czechia
Incyte Corporation

Active, not recruiting

A Study of INCB050465 in Relapsed or Refractory Follicular Lymphoma (CITADEL-203)

Lymphoma

United States, Spain, Italy, Israel, Poland, United Kingdom, Canada, Czechia, Germany, Denmark, Australia, Hungary, Sweden
Silence Therapeutics plc

Completed

A Study Investigate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic Syndrome

Non-transfusion-dependent Thalassemia | Low Risk Myelodysplastic Syndrome | Very-Low Risk Myelodysplastic Syndrome

Thailand, Israel, Jordan, United Kingdom, Germany, Italy, Malaysia
Celgene
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway...

Completed

A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia (BEYOND)

Thalassemia

United States, Greece, Italy, Lebanon, Thailand, United Kingdom
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion...

Completed

Mortality After Transfusion of Ever-pregnant Donor Red Blood Cells (MATER)

Anemia

Netherlands
Sangamo Therapeutics
Sanofi

Completed

A Study to Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta-thalassemia (TDT)

Transfusion Dependent Beta-thalassemia

United States
Vifor (International) Inc.
Labcorp Corporation of America Holdings, Inc

Completed

Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in β-thalassaemia (VITHAL)

Beta-Thalassemia | Non-transfusion-dependent Thalassemia

Greece, Israel, Italy, Lebanon, Thailand
Octapharma

Completed

Bleeding Incidence in VWD Patients Undergoing On-Demand Treatment

Von Willebrand Diseases

Lebanon, Croatia, United States, Hungary, Russian Federation, Ukraine, Belarus, Bulgaria
Westat
Versiti; American National Red Cross; The Institute for Transfusion Medicine

Completed

Strategies to Reduce Iron Deficiency (STRIDE)

Iron Deficiency

United States
Celgene
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway...

Active, not recruiting

A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve (COMMANDS)

Myelodysplastic Syndromes

United States, Australia, Austria, Belgium, Canada, Czechia, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Lithuania, Netherlands, Poland, Portugal, Russian Federation, Spain, Sweden, Switzerland, Taiwan, Turke... and more
Bayer

Terminated

Study of Copanlisib in Combination With Standard Immunochemotherapy in Relapsed Indolent Non-Hodgkin's Lymphoma (iNHL) (CHRONOS-4)

Lymphoma, Non-Hodgkin

United States, Hungary, China, Belgium, Korea, Republic of, France, Australia, Russian Federation, Taiwan, Denmark, Japan, United Kingdom, Spain, South Africa, Turkey, Romania, Singapore, Israel, Ireland, Canada, Poland, Greece, Cze... and more
University of Copenhagen
University of California, Los Angeles; World Anti-Doping Agency

Active, not recruiting

The Effect of Blood Donation on Hematological and Iron Indices and Detection of Autologous Blood Transfusion

Healthy

Denmark
Institute of Hematology & Blood Diseases Hospital...
EdiGene Inc.; The Affiliated Hospital Of Guizhou Medical University; Zunyi Medical...

Active, not recruiting

Safety and Efficacy Evaluation of ET-01 Transplantation in Subjects With Transfusion Dependent β-Thalassaemia

Transfusion Dependent Beta-Thalassaemia

China
Juan Pascual

Active, not recruiting

Red Blood Cell Exchange Transfusion as a Novel Treatment for GLUT1 Deficiency Syndrome

Glucose Transporter Type 1 Deficiency Syndrome | GLUT1DS1

United States
Mauricio Lynn

Available

HBOC-201 Expanded Access Protocol for Life-threatening Anemia for Whom Allogeneic Blood Transfusion is Not an Option

Anemia

United States
Daiichi Sankyo, Inc.

Completed

Quizartinib With Standard of Care Chemotherapy and as Continuation Therapy in Patients With Newly Diagnosed FLT3-ITD (+) Acute Myeloid Leukemia (AML) (QuANTUM-First)

Acute Myeloid Leukemia | Leukemia

Hong Kong, Canada, Belgium, France, Spain, Taiwan, United States, Australia, Czechia, Hungary, Italy, Israel, Japan, Korea, Republic of, Germany, China, Ukraine, Romania, Argentina, Croatia, Brazil, Serbia, Russian Federation, Portugal, Bulgari... and more
NHS Blood and Transplant
National Health and Medical Research Council, Australia; Monash University

Completed

TRial to EvaluAte Tranexamic Acid Therapy in Thrombocytopenia (TREATT)

Hemorrhage | Hematologic Neoplasms | Hematopoietic Stem Cell Transplantation

United Kingdom, Australia
Universitätsklinikum Köln

Completed

Extrauterine Placental Transfusion In Neonatal Resuscitation Of Very Low Birth Weight Infants (EXPLAIN)

Anemia | Very Low Birth Weight Infant | Placental Transfusion

Germany
Lancaster General Hospital

Active, not recruiting

Evaluation of TXA Prior to Surgery in the Geriatric Hip Fracture Population (TAHFT)

Hip Fractures

United States
Sofia Ramström

Enrolling by invitation

Transfusion of Whole Blood in Acute Bleeding (HEPEP)

Blood Transfusion | Acute Bleeding

Sweden
Sierra Oncology LLC - a GSK company

Completed

A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM)

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

Korea, Republic of, Canada, Hungary, Israel, Spain, United States, Australia, Taiwan, Singapore, Germany, Italy, France, Belgium, New Zealand, Austria, United Kingdom, Denmark, Bulgaria, Poland, Czechia, Romania, Sweden
Octapharma

Completed

Clinical Study to Investigate the Efficacy and Safety of Wilate During Prophylaxis in Previously Treated Patients With VWD

Von Willebrand Diseases

Lebanon, Croatia, United States, Belarus, Bulgaria, Hungary, Russian Federation, Ukraine
Imara, Inc.

Terminated

A Study of IMR-687 in Subjects With Sickle Cell Disease

Sickle Cell Disease

United States, Oman, Italy, United Kingdom, Lebanon, Greece, Morocco, Tunisia, Ghana, Kenya, Netherlands, Senegal, Uganda
Celgene

Active, not recruiting

A Study to Evaluate the Efficacy, Drug Levels and Safety of Luspatercept (ACE-536) for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes in Chinese and Japanese Participants With Ring Sideroblasts Who Require Red Blood Cell Transfusions

Myelodysplastic Syndromes

China, Japan
Cristina Martinez

Completed

Transfusion of Red Blood Cells, Tranexamic Acid and Fibrinogen Concentrate for Severe Trauma Hemorrhage

Hemorrhagic Shock

Spain
Cristina Martinez

Completed

Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock

Sepsis | Septic Shock

Spain
Ulrik Sartipy, MD, PhD
Karolinska Institutet

Active, not recruiting

HeAlth-data Register sTudies of Risk and Outcomes in Cardiac Surgery (HARTROCS)

Depression | Cardiovascular Diseases | Kidney Diseases | Diabetes Mellitus
Vanderbilt University Medical Center

Active, not recruiting

Reduction of Allogenic Blood Transfusion in Locally Advanced Kidney Cancer (RESTRICT)

Kidney Cancer

United States
Hospital for Special Surgery, New York

Completed

Oral Versus Intravenous Tranexamic Acid

Blood Loss | Blood Transfusion

United States
European Society for Blood and Marrow Transplantation
Genzyme, a Sanofi Company

Completed

Rabbit Antithymocyte Globulin (Thymoglobuline) With Ciclosporin for Patients With Acquired Aplastic Anaemia (RATGAA07)

Aplastic Anemia

Switzerland, United Kingdom, Germany, Italy, France, Saudi Arabia
Takeda

Completed

A Study of Oral Ixazomib Maintenance Therapy in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Not Treated With Stem Cell Transplantation (SCT)

Multiple Myeloma

France, Spain, United States, Taiwan, Korea, Republic of, Israel, Australia, Czechia, Hungary, Canada, Japan, Portugal, Singapore, United Kingdom, Italy, Sweden, Poland, Germany, China, Denmark, Greece, Thailand, Serbia, Turkey, Colombia, Russian Federation and more
Baxalta now part of Shire
Takeda Development Center Americas, Inc.

Active, not recruiting

A Study of PEGylated Recombinant Factor VIII (BAX855) in Previously Untreated Young Children With Severe Hemophilia A

Hemophilia A

Spain, United States, Denmark, Italy, Taiwan, Malaysia, Belgium, Thailand, Turkey, Austria, Bulgaria, Canada, Finland, France, Germany, Hong Kong, Hungary, Korea, Republic of, Netherlands, Norway, Singapore, Ukraine, United Kingdom
Erasme University Hospital
European Society of Intensive Care Medicine

Completed

TRansfusion Strategies in Acute Brain INjured Patients (TRAIN)

Blood Transfusion | Acute Brain Injury

Belgium
Consorci Sanitari Integral

Active, not recruiting

Perioperative Management of Preoperative Anemia in Colorectal Cancer

Anemia | Colorectal Cancer

Spain
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Pembrolizumab/Vibostolimab (MK-7684A) in Relapsed/Refractory Hematological Malignancies (MK-7684A-004, KEYVIBE-004)

Hematological Malignancies

United States, Canada, Brazil, Chile, Denmark, France, Germany, Hungary, Israel, Italy, Poland, Russian Federation, Spain, Taiwan, Turkey, Ukraine
Erasme University Hospital

Completed

Do Anesthesiologists Follow Guidelines on Perioperative Use of Tranexamic Acid? (Periop_TXA)

Blood Loss, Surgical | Blood Transfusion | Tranexamic Acid

Belgium
Celgene

Completed

A Safety and Efficacy Study to Evaluate Luspatercept in Subjects With Myeloproliferative Neoplasm-associated Myelofibrosis Who Have Anemia With and Without Red Blood Cell-transfusion Dependence

Primary Myelofibrosis | Anemia

United States, France, Italy, United Kingdom
Thomas Jefferson University

Withdrawn

Physical Activity in Transfusion Dependent Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes

United States
American Burn Association
U.S. Army Medical Research and Development Command

Completed

A Trial of Restrictive Versus Traditional Blood Transfusion Practices in Burn Patients

Burn Injury

United States, Canada, New Zealand
University Hospital, Brest

Completed

Liberal Versus Restrictive Transfusion Threshold in Oncologic surgerY (LIBERTY1)

Anemia | Oncologic Complications

France

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