Search clinical trials for: Single nucleotide polymorphism

Total 9595 results

Pfizer

Recruiting

A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors

Melanoma | Neoplasms | Renal Cell Carcinoma | Non-small-cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Urothelial Carcinoma | Colorectal Carcinoma | Ovarian Carcinoma

Puerto Rico, Japan, United States
Wake Forest University Health Sciences
United States Department of Defense

Not yet recruiting

Single Versus Dual Implant Fixation of Distal Femur Fractures (PRORP)

Articular Fractures

United States
Agios Pharmaceuticals, Inc.

Recruiting

A Safety Study of Single and Multiple Doses of AG-181 in Healthy Participants

Healthy Volunteers

United States
Shuhui Liang

Recruiting

Single-operator Versus Double-operator in Single-Balloon Enteroscopy (SBE)

Operation | Single-balloon Enteroscopy

China
Shanghai Pulmonary Hospital, Shanghai, China

Not yet recruiting

Neoadjuvant Therapy With Iruplinalkib for Potentially Resectable ALK Positive NSCLC: A Single Arm, Exploratory Trial

Potentially Resectable ALK Positive Non-Small Cell Lung Cancer
Eli Lilly and Company

Recruiting

A Study of LY3938577 in Healthy Participants and Participants With Type 1 Diabetes Mellitus (T1DM)

Healthy | Type 1 Diabetes Mellitus

Germany
Fundación IVI
Instituto Valenciano de Infertilidad, IVI VALENCIA

Recruiting

Impact of IVF Hormonal Therapy on Endometrial Receptivity and Endometrial Senescent Cell Pathological Accumulation (HormoSenoRec)

Endometrial Receptivity

Spain
Xi'an Xintong Pharmaceutical Research Co.,Ltd.

Recruiting

Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy Subjects (XT1061)

Chronic Hepatitis b

China
Johns Hopkins University

Not yet recruiting

Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome

Staphylococcus Aureus | Microbial Colonization | Neonatal Infection

United States
Qompium NV

Recruiting

FibriCheck Data Registry (FDR)

Cardiac Arrhythmia

Belgium
Denali Therapeutics Inc.

Recruiting

A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants

Healthy Volunteers

United States
Zunyi Medical College

Recruiting

CYP2C19 Genotype-Guided P2Y12 Receptor Inhibitor Selection After Complex Percutaneous Coronary Intervention

ACS - Acute Coronary Syndrome | CYP2C19 Polymorphism

China
GEN İlaç ve Sağlık Ürünleri A.Ş.
Sulfateq B.V.

Recruiting

A First-In-Human Study of Single and Multiple Ascending Doses of Oral SUL-238 in Healthy Subjects

Healthy Subjects

Turkey
Jiangsu Aidea Pharmaceutical Co., Ltd
Chengdu Aidea Pharmaceutical Technology Co., Ltd

Recruiting

Single Ascending Dose, Food Effects and Drug-Drug Interactions of ACC017 Tablets in Healthy Adult Participants

Healthy Adult Participants

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Efficacy and Safety of Sivelestat in Preventing Postoperative Acute Respiratory Distress Syndrome After Cardiac Surgery :a Single Centre Random Control Trial.

Cardiac Disease
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls

Type 2 Diabetes Mellitus | Genetic Mutations | Gene Polymorphisms | Susceptibility, Genetic

China
University of Mississippi Medical Center
The Craig H. Neilsen Foundation; Methodist Rehabilitation Center

Not yet recruiting

Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury

Spinal Cord Injuries | Spinal Cord Injury | Spinal Cord Injury Cervical | Spinal Cord Injury Thoracic

United States
University of Manitoba

Not yet recruiting

Outcomes of MIST for BPH: A Single-Institution Prospective Study

Benign Prostatic Hyperplasia

Canada
GERCOR - Multidisciplinary Oncology Cooperative...

Not yet recruiting

POP-UP: a Single-arm, Two-cohort Study: Trimodal Prehab for Upper GI and Pancreatic Cancer (POP-UP)

Esophageal Cancer | Pancreatic Ductal Adenocarcinoma
National Institute of Cardiology, Warsaw, Poland

Recruiting

Optimal Medical Treatment of Difficult-to-treat Hypertension (OPTIMAL-HT)

Hypertension

Poland
Biora Therapeutics, Inc.

Recruiting

BT-600 Single and Multiple Ascending Oral Doses in Healthy Adult Subjects

Healthy

United States
S.LAB (SOLOWAYS)
Center of New Medical Technologies

Not yet recruiting

Trial to Evaluate the Efficacy of a Zinc, Selenium, and L-Tyrosine Supplement in the Prevention of Thyrotoxicosis in Subjects With r25191G/A SEPP1 Polymorphism (ZEST-PREP)

Thyrotoxicosis

Russian Federation
University of Social Sciences and Humanities, Warsaw
National Science Centre, Poland

Recruiting

The Effect of an Online ACT Intervention on Meaning-Making Process in Cancer Patients Following Hematopoietic Cell Transplantation

Hematopoietic Cell Transplantation Recipient | Acceptance and Commitment Therapy

Poland
Replimune Inc.

Not yet recruiting

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs (IGNYTE-3)

Advanced Melanoma
University Hospital, Clermont-Ferrand

Recruiting

Single-center Study Measuring OSDI Dry Eye Score in Patients Undergoing an Anti-VEGF Induction Protocol (PISO)

Macular Degeneration | Diabetic Macular Edema | Retinal Vein Occlusion

France
Central Adelaide Local Health Network Incorporated
University of Adelaide

Recruiting

Effect of Chitodex Gel in Tympanoplasty Surgery

Surgery | Otitis Media | Tympanic Membrane Perforation | Tympanic Membrane Inflammation

Australia
Al-Azhar University

Recruiting

The Effect of Clinical Experience on the Quality of Obturation and Periapical Changes of Teeth Treated With Matched Cones in Combination With Bioceramic Sealer

Obturation

Egypt
Azienda Ospedaliera SS. Antonio e Biagio e Cesare...

Recruiting

Single Breath Counting Test for Acute Respiratory Failure in Emergency Department (STARED)

Acute Respiratory Failure

Italy
Servier Russia

Not yet recruiting

Evaluation of the Antihypertensive effectIveness, Tolerability, and Adherence With Amlodipine/ Indapamide/ Perindopril Triple Single-pill Combination in Hypertensive Patients Without Concomitant Antihypertensive Therapy (TRIPTYCH) (TRIPTYCH)

Arterial Hypertension | HTN
Lille Catholic University

Not yet recruiting

Gait Initiation and Transition From Double to Single Support in Patients With Unilateral Primary Coxarthrosis (COXAM)

Primary; Coxarthrosis

France
Shanxi Province Cancer Hospital

Not yet recruiting

A Single-arm, Single-center, Open-label Phase II Study of Zanubrutinib Combined With R-CHOP/R-DHAP in Newly Diagnosed Mantle CellLymphoma Patients (Z+RCHOP/RDHAP)

Mantle Cell Lymphoma

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DM

Type 2 Diabetes Mellitus | Susceptibility, Genetic

China
Qilu Hospital of Shandong University

Not yet recruiting

Diagnosis of Myocardial Ischemia With MCG Using SPECT as a Reference Standard

Myocardial Ischemia | Chest Pain | Stenosis

China
University of Nove de Julho
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Not yet recruiting

Post-Endodontic Instrumentation Pain After in a Single Session Associated With Photobiomodulation

Pain, Postoperative | Endodontically Treated Teeth
Centre Hospitalier Universitaire de Saint Etienne

Not yet recruiting

Evaluation of First-void Urine as an Alternative to Cervical Sampling for Human Papillomavirus (HPV) Testing in Cervical Cancer Screening (Single-center Study). (URAPREV)

Uterine Cervical Cancer

France
Nantes University Hospital

Not yet recruiting

Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation (CY-MET-RIC)

Hematologic Malignancy | Graft Versus Host Disease
Zhe Meng

Recruiting

A Single Center Randomized Controlled Study on the Promotion of Rapid Recovery

Primary Aldosteronism | Cushing Syndrome | Nonfunctional Adrenal Cortex Adenoma

China
Johnson & Johnson Surgical Vision, Inc.

Recruiting

A Multicenter, Observational, Single Arm Study of the TECNIS Presbyopia-correcting Intraocular Lens

Cataracts

Austria, France, Germany, Korea, Republic of, Netherlands, Spain
Royal Marsden NHS Foundation Trust
Gilead Sciences

Not yet recruiting

Peri-operative Zimberelimab (Anti-PD-1) vs Zimberelimab in Combination With Domvanalimab (Anti-TIGIT) in Resectable Mismatch Repair Deficient/Micro-satellite Unstable Gastric and Gastro-oesophageal Junctional Adenocarcinoma (ZODIAC) (ZODIAC)

Metastatic Gastric Cancer | Metastatic Esophageal Cancer
University of Nove de Julho

Recruiting

Acute Cardiovascular Responses to a Single Exercise Session in Patients With Post-COVID-19 Syndrome (ExPostCovid-19)

Post-Acute COVID-19 Syndrome

Brazil
Massachusetts General Hospital
National Institute of Neurological Disorders and Stroke (NINDS)

Not yet recruiting

Physiology of Human Brain Connectivity

Healthy
Ruijin Hospital
Intuitive Surgical

Recruiting

Valuate the Clinical Performance and Safety of da Vinci SP Surgical System

Thoracic Surgery | da Vinci SP Surgical System

China
ASST Fatebenefratelli Sacco

Not yet recruiting

Clonal Hematopoiesis in Giant Cell Arteritis (CH-GCA)

Giant Cell Arteritis | Temporal Arteritis | Clonal Hematopoiesis of Indeterminate Potential | Horton Disease | Systemic Vasculitis Primary
Eli Lilly and Company

Recruiting

A Study to Investigate the Safety and Pharmacokinetics of Lebrikizumab in Healthy Chinese Participants

Healthy

China
Azienda Unità Sanitaria Locale Reggio Emilia

Recruiting

Rehabilitation Intervention to Prevent Adverse Events Related to Androgen-deprivation Therapy (ADT) in Patients With Metastatic Prostate Cancer (PCa): a Single Arm Feasibility Study (ReCaP Study) (ReCaP)

Rehabilitation | Metastatic Prostate Cancer (PCa) in ADT

Italy
Shanghai Changzheng Hospital
Shanghai Zhongshan Hospital; The First Affiliated Hospital of Guangzhou Medical... and other collaborators

Recruiting

Extraperitoneal SINgle-port rObotic-assisted Radical Prostatectomy (RARP) Versus Transperitoneal Multi-port RARP in the Treatment Of Prostate Cancer (SINO-TOP)

Prostate Adenocarcinoma | Localized Prostate Carcinoma

China
Yunnan Cancer Hospital
Beijing Bethune Charitable Foundation

Recruiting

Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer (ESTIMATE)

Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer

China
University of Delaware

Recruiting

Testing Tactile Aids With Blind Subjects

Blindness | Vision, Low

United States
Wang Ouchen

Recruiting

A Prospective, Open, Multicenter Single-arm Clinical Studie of Docetaxel, Carboplatin Combined With Inetetamab and Pyrotinib in the Treatment of Local-advanced HER2-positive Breast Cancer (neoPICD)

Breast Neoplasm Female

China
Wuhan Union Hospital, China
Renmin Hospital of Wuhan University

Recruiting

Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study

Locally Advanced Rectal Cancer

China

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