Search clinical trials for: molecular profile

Total 99352 results

Brugmann University Hospital

Completed

Evaluation of the Pharmacokinetic Profile of Tranexamic Acid, After Injection in a Knee Neo-articulation.

Knee Prosthesis

Belgium
Repurposed Therapeutics, Inc.

Terminated

Pharmacokinetic and Efficacy Profile Intranasal Scopolamine Spray

Motion Sickness

United States
Arbeitsgemeinschaft medikamentoese Tumortherapie
Schering-Plough

Completed

A Pilot Trial With Subcutaneous Alemtuzumab and Oral Fludarabinephosphate for the Determination of Safety, Efficacy and Molecular Profiling for the Prediction of Response

B-cell Chronic Lymphocytic Leukemia

Austria
Masonic Cancer Center, University of Minnesota

Terminated

CpG 7909 in Treating Patients Who Have Undergone Autologous Stem Cell Transplant

Lymphoma | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Germ Cell Tumor

United States
Tritech Biopharmaceuticals Co., Ltd.
A2 Healthcare Taiwan Corporation

Unknown

A Study to Assess the Safety and Tolerability Profile of TR399 in Healthy Volunteers and Erectile Dysfunction Patients

Erectile Dysfunction

Taiwan
University of Washington
National Cancer Institute (NCI)

Completed

Sorafenib Tosylate and Gene Expression Analysis in Patients Undergoing Surgery For High-Risk Localized Prostate Cancer

Stage II Prostate Cancer | Stage III Prostate Cancer | Adenocarcinoma of the Prostate

United States
GlaxoSmithKline

Completed

A Phase I Study to Investigate the Safety, Tolerability and Pharmacokinetic Profile of of GSK2118436 in Japanese Subjects With BRAF Mutation Positive Solid Tumors

Cancer

Japan
GlaxoSmithKline

Completed

Study to Evaluate the 24-Hour Pulmonary Function Profile of Fluticasone Furoate/Vilanterol (FF/VI) Inhalation Powder 100/25mcg Once Daily Compared With Tiotropium Bromide Inhalation Powder 18mcg Once Daily in Subjects With COPD Who Have or Are At Risk for Co-morbid Cardiovascular Disease

Pulmonary Disease, Chronic Obstructive

United States, Canada, Germany, Romania, Poland, Czechia
GlaxoSmithKline

Completed

Study to Evaluate the 24-Hour Pulmonary Function Profile of Fluticasone Furoate (FF) /GW642444 (Vilanterol) (VI) Inhalation Powder 100/25mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Germany, Poland, Romania, United States, Czechia, Russian Federation
Caris Science, Inc.

Enrolling by invitation

POA Retrospective Repository

Oncology | Solid Tumor, Adult

United States
Centro Universitario de Ciencias de la Salud, Mexico

Completed

Effect of Oral Administration of a Herbarium Mixture (Guazuma Ulmifolia and Tecoma Stans) on Metabolic Profile in Type 2 Diabetic Patients (GUATECO)

Type 2 Diabetes Mellitus
Stanford University

Completed

Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDur® After Cesarean Delivery

Epidural Analgesia, Obstetric

United States
Rambam Health Care Campus

Completed

Mechanism-based Choice of Therapy for Pain: Can Successful Prevention of Migraine be Coupled to a Psychophysical Pain Modulation Profile?

Migraine

Israel
Rambam Health Care Campus

Completed

Pain Prevention and Treatment Through the Enhancement of the Anti-nociceptive Component of Pain Modulation Profiles

Pain

Israel
Rambam Health Care Campus

Terminated

Shifting Pain Modulation From Pro-to Anti-nociceptive

Post-operative Chronic Pain
Pfizer

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]NXL104

Healthy

United Kingdom
Bial - Portela C S.A.

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-BIA 9-1067

Parkinson Disease

United Kingdom
Genentech, Inc.

Completed

A Study to Evaluate the Effects of Rituximab on Immune Responses in Subjects With Active Rheumatoid Arthritis Receiving Background Methotrexate (SIERRA)

Rheumatoid Arthritis

United States
Hospices Civils de Lyon

Completed

Safety Profile of IntRAvenous Lidocaine Use in Coelioscopic Bariatric Surgery (SPIRAL)

Obesity | Bariatric Surgery

France
GlaxoSmithKline

Completed

Pharmacokinetic Profiles Of Amoxicillin 2000 mg And Clavulanate 125 mg In Adolescent Patients

Infections, Respiratory Tract

United States
Taichung Veterans General Hospital

Unknown

Application of Proteome Profiler Antibody Arrays to Find Angiogenetic Predictors in Glioma Paitents.

Glioblastoma Multiforme | Angiogenesis

Taiwan
BC World Pharm Co. Ltd.

Completed

Evaluating of Pharmacokinetic Profile of BCWP_C003 and Co-administration of Rosuvastatin and Metformin

Healthy

Korea, Republic of
National Cancer Institute (NCI)

Completed

Construction and Use of Lung Tumor Microarray for the Analysis of Gene Expression in Lung Cancer

Lung Cancer

United States
National Institute of Nursing Research (NINR)

Completed

Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain

Pain

United States
Hospital Universitari Vall d'Hebron Research Institute
Gilead Sciences

Completed

Evolution of Plasma Lipid Profile in Patients With HIV1 Who Change Atripla to Eviplera Compared to Continue With Atripla

HIV-1

Spain
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer

Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Adenocarcinoma of the Esophagus | Recurrent Esophageal Cancer | Stage IV Esophageal Cancer | Diffuse Adenocarcinoma of the Stomach | Intestinal Adenocarcinoma of the Stomach | Mixed Adenocarcinoma...

United States
Medical University of Vienna

Completed

Concentration of Ampicillin / Sulbactam and Amoxicillin / Clavulanic Acid in the Blood During Renal Replacement Therapy in Longterm Renal Replacement Therapy Patients

Infection During Hemodialysis

Austria
Merck Sharp & Dohme LLC

Completed

A Study Comparing the Pharmacokinetic and Pharmacodynamic Profiles for Sitagliptin, Saxagliptin and Vildagliptin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-142)

Type 2 Diabetes Mellitus
University of Florida

Completed

Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With Morphine

Coronary Artery Disease

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Completed

Biomarker Study of Blood Samples From Patients With Non-Small Cell Lung Cancer Treated With Carboplatin and Paclitaxel With or Without Bevacizumab

Lung Cancer
Centre Hospitalier Universitaire, Amiens

Withdrawn

Evaluation of the Pharmacokinetic Profile, Pharmacodynamic Effects, Acceptability and Tolerability of an Oral Amiodarone Solution of 15 mg / mL in Children With Supra Ventricular Tachycardia (Enteramio)

Supraventricular Tachycardia

France
National Cancer Institute (NCI)

Terminated

UCN-01 (7-Hydroxystaurosporine) to Treat Relapsed T-Cell Lymphomas

Lymphoma, T-Cell | Lymphoma, Large-Cell, Ki-1

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Withdrawn

S0716 Vandetanib and Docetaxel in Treating Patients With Advanced Solid Tumors

Breast Cancer | Head and Neck Cancer | Lung Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific
William Beaumont Hospitals

Terminated

Side Effect Profiles of Brand Name Versus Generic Oral Contraceptives

Contraception

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

FDG-PET in Advanced Melanoma

Recurrent Melanoma | Stage IV Melanoma | Stage IIIA Melanoma | Stage IIIB Melanoma | Stage IIIC Melanoma

United States
Bial - Portela C S.A.

Completed

Pharmacokinetic Profile of BIA 6-512 in Healthy Elderly Subjects Versus Healthy Young Subjects

Parkinson Disease

Germany
Dong Wha Pharmaceutical Co. Ltd.
The Catholic University of Korea; Konkuk University Hospital; Wonkwang University and other collaborators

Completed

A Study to Compare the Pharmacokinetics Profile of DWCZP Tablet 100mg and Clozaril® Tablet 100mg (DWCZP-I-1)

Schizophrenia

Korea, Republic of
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine and Oxaliplatin in Treating Patients With Pancreatic Cancer That Can Be Removed By Surgery

Pancreatic Cancer

United States
Praxis für kleine und grosse Leute
Dr med Kurt von Siebenthal, Facharztpraxis für Pädiatrie, Winterthur, Switzerland and other collaborators

Unknown

Atomoxetine, Diurnal Profiles of Cortisol and α-amylase (ADHDstress)

ADHD

Switzerland
MerLion Pharmaceuticals GmbH

Completed

Pharmacokinetic Profile in Plasma and Epithelial Lining Fluid of Finafloxacin

Safety and Tolerability

United States
Egalet Ltd

Completed

Assessment of Nasal Deposition and Clearance of Ketorolac Solution Administered Using the Valois Nasal Spray Device

Healthy Subjects

United Kingdom
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Lumiracoxib in Patients With Osteoarthritis and With Controlled Hypertension

Osteoarthritis | Controlled Hypertension

Germany, United States
Leiden University Medical Center

Completed

Effect of Neuromuscular Reversal With Sugammadex on Postoperative Recovery Profile (Neuropa)

Postoperative Respiratory Condition

Netherlands
University of Zagreb
University of Rijeka

Completed

Molecular Mechanisms of the Development of Precancerous and Cancerous Lesions of the Oral Cavity

Oral Squamous Cell Carcinoma | Oral Lichen Planus

Croatia
Leiden University Medical Center
Netherlands Heart Foundation

Completed

Rosuvastatin Use to Improve the Coagulation Profile in Patients With Venous Thrombosis (START)

Deep Vein Thrombosis | Pulmonary Embolism

Netherlands
Pfizer

Completed

An Investigational Drug, PF-02341066, Is Being Studied In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene

Carcinoma, Non-Small-Cell Lung

United States, Canada, Spain, China, Brazil, United Kingdom, Japan, Poland, Australia, France, Ireland, Taiwan, Italy, Germany, Netherlands, Korea, Republic of, Bulgaria, Greece, Hong Kong, Hungary, Russian Federation, Sweden
Pfizer

Completed

An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene

Carcinoma, Non-Small-Cell Lung

United States, Canada, Spain, China, United Kingdom, Poland, France, Ireland, Japan, Taiwan, Germany, Netherlands, Italy, Brazil, Russian Federation, Korea, Republic of, Australia, Bulgaria, Greece, Hong Kong, Hungary, Sweden
HK inno.N Corporation

Completed

Phase 1 Study to Compare the Safety, Pharmacokinetic Profiles of CJ-30056 and Lipitor 20mg/Glucophage SR 750mg

Healthy
HK inno.N Corporation

Completed

Phase 1 Study to Compare the Safety, Pharmacokinetic Profiles of CJ-30056 and Lipitor/Glucophage XR

Healthy Volunteers

Korea, Republic of
University of Utah
Cubist Pharmaceuticals LLC

Completed

Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin

Pharmacokinetics | Drug Interactions

United States

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