Search clinical trials for: parasitic infections

Total 56469 results

Drugs for Neglected Diseases
Bayer

Active, not recruiting

Emodepside Phase II Trial for Treatment of Onchocerciasis

Onchocerciasis

Ghana, Congo, The Democratic Republic of the
Yarmouk University

Completed

Spleen Preserving Surgery for Splenic Hydatidosis: A Cohort Study on Short and Long-Term Outcomes

Minimally Invasive Surgery | Hydatid Disease | Spleen-Preserving Surgery | Echinococcus Granulosus Infection

Jordan
Barcelona Institute for Global Health
London School of Hygiene and Tropical Medicine; Leiden University Medical Center and other collaborators

Terminated

Evaluation of Effectiveness of ALBENDAZOLIVERMECTIN Coformulation vs ALBENDAZOLE for Treatment of Intestinal Worms (ALIVE)

Helminthes; Infestation, Intestinal

Ethiopia, Kenya, Mozambique
Drugs for Neglected Diseases
Makerere University; The Netherlands Cancer Institute; Kenya Medical Research... and other collaborators

Completed

Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa

Visceral Leishmaniasis

Ethiopia, Kenya, Sudan, Uganda
University of Oxford

Completed

Child Follow-up Until 2 Years

Pregnancy | Malaria

Thailand
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; Bill and Melinda Gates Foundation and other collaborators

Completed

Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso (MALCOV)

Covid-19 | Malaria

Burkina Faso, Kenya
Drugs for Neglected Diseases

Active, not recruiting

Combination, Miltefosine Monotherapy for Cutaneous Leishmaniasis in New World

Cutaneous Leishmaniases

Peru, Bolivia, Brazil, Panama
Centre Hospitalier Universitaire Dijon

Terminated

Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital Toxoplasmosis (TOSCANE)

Congenital Toxoplasmosis

France
GlaxoSmithKline

Completed

Safety, Tolerability and Pharmacokinetics (PK) Investigation of GSK3494245 in Healthy Participants

Leishmaniasis

United Kingdom
Centro de Investigação em Saúde de Manhiça
University Health Network, Toronto; Barcelona Institute for Global Health

Completed

Rosiglitazone Adjunctive Therapy for Severe Malaria in Children (ROSI)

Malaria

Mozambique
GlaxoSmithKline

Completed

An Ancillary Study Protocol to GSK's Phase IIb Malaria Vaccine Trial Entitled "Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age"

Malaria

Ghana, Kenya
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Clinton Health... and other collaborators

Completed

Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Kenya

Malaria | Febrile Illness

Kenya
BioMérieux

Completed

Impact of Differential and Systematic Diagnosis of Dengue, Chikungunya and Malaria on Patient Management and Antibiotic Use in West Africa

Malaria | Dengue | Chikungunya

Burkina Faso, Côte D'Ivoire
Novartis Pharmaceuticals
European and Developing Countries Clinical Trials Partnership (EDCTP); Medicines... and other collaborators

Active, not recruiting

Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria (CALINA)

Plasmodium Falciparum Malaria

Burkina Faso, Congo, The Democratic Republic of the
Sanaria Inc.
National Institute of Allergy and Infectious Diseases (NIAID); Malaria Research... and other collaborators

Completed

PfSPZ Vaccine Trial in Malian Children

Malaria | Malaria,Falciparum

Mali
University of Washington
London School of Hygiene and Tropical Medicine; National Institute of Allergy... and other collaborators

Active, not recruiting

Field Studies on the Feasibility of Interrupting the Transmission of Soil-transmitted Helminths (STH)

Filariasis | Helminthiasis

India, Benin, Malawi
University of California, San Francisco
Research to Prevent Blindness

Active, not recruiting

Parasitic Ulcer Treatment Trial Pilot

Acanthamoeba Keratitis

India
Ministry of Public Health, Democratic Republic...
Centers for Disease Control and Prevention; Global Fund

Active, not recruiting

Test Efficacy Study on the Recommended Antimalarial Drugs in the Democratic Republic of the Congo (TES2022)

Uncomplicated Plasmodium Falciparum Malaria

Congo, The Democratic Republic of the
Jhpiego
United States Agency for International Development (USAID); Centers for Disease... and other collaborators

Completed

Malaria Therapeutic Efficacy Study, Rwanda

Uncomplicated Malaria

Rwanda
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Malaria Transmission in Humans and Mosquitoes at the Area of Sabou, Burkina Faso

Malaria

Burkina Faso
Institute of Tropical Medicine, Belgium
Drugs for Neglected Diseases; Institut National de Recherche Biomédicale. Kinshasa... and other collaborators

Withdrawn

Screen and Treat Implementation for HAT Control

Trypanosomiasis, African | Sleeping Sickness
University of North Carolina, Chapel Hill
Fogarty International Center of the National Institute of Health

Completed

HIV And Parasitic Infection (HAPI) Study (HAPI)

HIV Coinfection

Malawi
Michigan State University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Treating Brain Swelling in Pediatric Cerebral Malaria (TBS)

Malaria, Cerebral

Malawi
Foundation for Innovative New Diagnostics, Switzerland
Australian Government

Completed

Clinical Validation of Novel Malaria Diagnostic Tools for POC Point-of-Care Testing

Malaria | Diagnoses Disease | RDT

Rwanda
Jennifer Keiser
National Centre for Parasitology, Entomology and Malaria Control, Cambodia

Completed

Efficacy and Safety of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis (StrongMoxi_KH)

Strongyloides Stercoralis Infection

Cambodia
Jennifer Keiser
Centre Suisse de Recherches Scientifiques en Cote d'Ivoire

Completed

Efficacy and Safety of MOX/ALB Co-administration

Hookworm Infections | Ascariasis | Trichuriasis

Côte D'Ivoire
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); Stanford University and other collaborators

Active, not recruiting

CHILD (Child Health and Infection With Low Density) Malaria (CHILD Malaria)

Malaria | Malaria,Falciparum

Tanzania
Sanaria Inc.
University of Maryland, Baltimore

Terminated

A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI

Malaria | Malaria,Falciparum

United States
National Institute of Allergy and Infectious Diseases...

Completed

An Observational Study to Assess the Prevalence and Outcomes of Primary Pulmonary Coccidioidomycosis in Persons Aged > / = 14 Years Presenting With Community Acquired Pneumonia (CAP) in Endemic Areas (SAnds-PPC)

Pneumonia | Coccidioidomycosis

United States
Medicines for Malaria Venture
GlaxoSmithKline; ICON plc; QIMR Berghofer Medical Research Institute; Swiss BioQuant... and other collaborators

Completed

Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum

Pathologic Processes | Infections | Systemic Inflammatory Response Syndrome | Inflammation | Vector Borne Diseases | Parasitic Diseases | Protozoan Infections | Malaria | Parasitemia | Malaria,Falciparum | Anti-Infective Agents | Antimalarials

Australia
Medicines for Malaria Venture

Completed

Piperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers. (PedPQP(BA/FE))

Malaria

Tanzania
University of Brasilia

Active, not recruiting

The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in Brazil

Leishmaniasis

Brazil
Brian Foy
National Institute of Allergy and Infectious Diseases (NIAID); Radboud University... and other collaborators

Active, not recruiting

Repeat Ivermectin Mass Drug Administrations for MALaria Control II (RIMDAMAL II)

Malaria

Burkina Faso
Foundation for Innovative New Diagnostics, Switzerland
Makerere University; Ministry of Public Health, Democratic Republic of the...

Withdrawn

Prospective Evaluation of an RDT to Screen for Gambiense HAT and Diagnose P. Falciparum Malaria

Human African Trypanosomiasis
Baylor College of Medicine
George Washington University; Makerere University Walter Reed Project

Active, not recruiting

Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults

Schistosomiasis | Schistosoma Mansoni

Uganda
University of California, San Francisco

No longer available

Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World Leishmaniasis

Leishmaniasis, Cutaneous | Leishmaniasis, Mucocutaneous

United States
Prof. Dawit Wolday
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); European...

Completed

LAMP Assay for the Diagnosis of Visceral Leishmaniasis (EvaLAMP)

Visceral Leishmaniasis

Ethiopia
Hospital Universitari Vall d'Hebron Research Institute

Completed

Evaluation of Different Benznidazole Regimens for the Treatment of Chronic Chagas Disease. (MULTIBENZ)

Chagas Disease | Trypanosoma Cruzi Infection

Argentina, Spain, Brazil, Colombia
Medicines for Malaria Venture
Shin Poong Pharmaceutical Co. Ltd.

Completed

Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations in Healthy Volunteers

Malaria

Korea, Republic of
PATH

Completed

Stimulating Private Sector Malaria Control (Outgrowers)

Malaria

Zambia
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate

Malaria

Switzerland
Universidade Nova de Lisboa
Centro de Investigação Operacional da Beira, Mozambique; Fundação Belmiro de...

Active, not recruiting

Evaluation of IR3535 as a Spatial Repellent for Malaria Control. (REPELMALARIA)

Malaria

Mozambique
Centro de Investigação em Saúde de Manhiça
United States Agency for International Development (USAID)

Active, not recruiting

In Vivo Efficacy of Artemether-Lumefantrine, Amodiaquine-Artesunate, Dihydroartemisinin-Piperaquine, and Pironaridine-Artesunate in Mozambique (MEFI_IV)

Malaria

Mozambique
University of Oxford
Kinshasa School of Public Health; Wellcome Sanger Institute

Completed

Monitoring Pregnant Women for Antimalarial Drug Resistance (MIRANDA)

Malaria

Congo, The Democratic Republic of the
R. Kiplin Guy
Eisai Inc.; Asociacion Civil Selva Amazonica; Global Health Innovative Technology...

Completed

Efficacy of SJ733 in Adults With Uncomplicated Plasmodium Falciparum or Vivax Malaria

Malaria, Falciparum | Malaria, Vivax

Peru
Malaria Consortium
London School of Hygiene and Tropical Medicine; Northwestern University; Nigerian...

Active, not recruiting

Perennial Malaria Chemoprevention (PMC) Effect Study (PMCEffect)

Malaria

Nigeria
University of Notre Dame
Institut Pierre Richet; In2Care

Active, not recruiting

EaveTubes for Vector Control

Malaria

Côte D'Ivoire
Technical University of Munich
Swiss Tropical & Public Health Institute; Makerere University; European and Developing... and other collaborators

Active, not recruiting

Adoption of L-PZQ for Schistosomiasis by Endemic Counties - Social Science Research Study (ADOPT)

Social Acceptance | Schistosomiasis in Children

Uganda, Kenya, Côte D'Ivoire
University of Ghana
University of Rostock; Shai-Osudoku District Hospital; Kumasi Technical University and other collaborators

Active, not recruiting

Africa Ready Malaria Screening (ARMS)

Malaria

Ghana
Johns Hopkins Bloomberg School of Public Health
Tropical Diseases Research Centre

Active, not recruiting

Pharmacokinetics and Pharmacodynamics of the Gametocytocidal and Post-treatment Chemoprotective Effects of Antimalarials

Uncomplicated Falciparum Malaria

Zambia

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