Search clinical trials for: primary immune deficiencies

Total 73252 results

National Cancer Institute (NCI)

Recruiting

Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment

Refractory B-Cell Non-Hodgkin Lymphoma | Refractory T-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent T-Cell Non-Hodgkin Lymphoma | Recurrent Primary Cutaneous... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Intracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T-lymphocytes) for the Treatment of Primary Central Nervous System Lymphoma

Central Nervous System Lymphoma

United States
PATH
Bill and Melinda Gates Foundation; Centre National de Greffe de Moelle Osseuse and other collaborators

Not yet recruiting

Evaluation of an IgG Deficiency Rapid Screening Test: A Performance Study With Primary Immunodeficiency (PID) Patients in Tunisia

Primary Immunodeficiency Diseases

Tunisia
Salubris Biotherapeutics Inc

Recruiting

Study of JK08 in Patients With Unresectable Locally Advanced or Metastatic Cancer

Melanoma | Clear Cell Renal Cell Carcinoma | Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | Advanced Solid Tumor | Epithelial Ovarian Cancer | Non-small Cell... and other conditions

Belgium, Spain
Universidad de Concepcion
Universidad de Valparaiso; Comisión Nacional de Investigación Científica y... and other collaborators

Recruiting

Pictograms to Facilitate Comprehension of Medical Indications (SIMAP)

Adherence, Medication | Primary Health Care | Asthma Chronic

Chile
Peking University Third Hospital

Recruiting

Clinical Cohort Study in Patients With Different Subtypes of Primary Sjogren Syndrome Related Dry Eye (pSS)

Dry Eye

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Orelabrutinib,Rituximab and Methotrexate in Newly Diagnosed Primary Central Nervous System Lymphoma

Primary Central Nervous System Lymphoma

China
Harvard University
Catholic University of the Sacred Heart

Recruiting

A Mindful Community for People With ALS and Their Primary Caregivers

Amyotrophic Lateral Sclerosis | Caregiver Burden

United States
Amgen

Recruiting

Study of Daxdilimab (HZN-7734) in Patients With Moderate-to-Severe Primary Discoid Lupus Erythematosus (RECAST DLE)

Discoid Lupus Erythematosus

United States, Germany, Canada, France, Greece, Denmark, Brazil, Bulgaria, Czechia, Argentina, Poland
Eunice Kennedy Shriver National Institute of Child...

Recruiting

Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C

Niemann-Pick Disease, Type C

United States
Angelica Lindén Hirschberg

Recruiting

Immunomodulatory Therapy in Women With Autoimmune Premature Ovarian Insufficiency

Autoimmune Diseases | Premature Ovarian Insufficiency

Sweden
Patrick C. Johnson, MD
AstraZeneca

Recruiting

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Refractory B-Cell Non-Hodgkin Lymphoma | Diffuse Large B-cell Lymphoma (DLBCL) | Grade 3b Follicular Lymphoma | Refractory Aggressive B-cell Lymphomas | Aggressive B-cell NHL | De Novo or Transformed Indolent B-cell Lymphoma | DLBCL, Nos Genetic Subtypes | T Cell/Histiocyte-rich Large B-cell Lymphoma and other conditions

United States
Takeda

Recruiting

A Study to Review the Treatment and Outcomes of Teenagers and Adults With Non-histaminergic Angioedema With Normal C1 Inhibitor in Canada (PROSPECT)

Angioedema | Hereditary Angioedema (HAE)

Canada
National Institute of Arthritis and Musculoskeletal...

Recruiting

Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires

Systemic Lupus Erythematosus (Sle) | Primary Ovarian Insufficiency (Poi)

United States
Danish Headache Center

Recruiting

The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain.

Headache | Migraine Without Aura | Migraine With Aura

Denmark
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

A Clinical Trial to Assess Safety and Efficacy of Daratumumab in the Treatment of Primary Immune Thrombocytopenia

Immune Thrombocytopenia
National Cancer Institute (NCI)

Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Anatomic Stage III Breast Cancer AJCC v8 | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid... and other conditions

United States, Puerto Rico
University of Alabama at Birmingham

Recruiting

Cancer and Aging Resilience Evaluation in Older Adults With Hematologic Malignancies: The CARE-Heme Registry (CARE-Heme)

Multiple Myeloma | Amyloidosis | Plasma Cell Leukemia

United States
Affiliated Hospital to Academy of Military Medical...

Recruiting

Orelabrutinib,Rituximab and Methotrexate in Newly-diagnosed Primary Central Nervous System Lymphoma(PCNSL) (RMO)

Primary Central Nervous System Lymphoma

China
Schrödinger, Inc.

Recruiting

Study of SGR-1505 in Mature B-Cell Neoplasms

Follicular Lymphoma | Splenic Marginal Zone Lymphoma | Burkitt Lymphoma | Plasmablastic Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Non Hodgkin Lymphoma | Primary Effusion Lymphoma | DLBCL | High-grade B-cell Lymphoma | Primary Mediastinal... and other conditions

United States, Moldova, Republic of
Ronald Buckanovich
Genentech, Inc.

Recruiting

Vismodegib Combined With Atezolizumab in Platinum Resistant Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

PARP Inhibitor | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Hedgehog Inhibitor

United States
RenJi Hospital

Not yet recruiting

Efficacy and Safety of the Treatment of Primary Membranous Nephropathy: A Randomized Clinical Trial

Efficacy and Safety
University Hospital, Montpellier

Recruiting

Quantification and Characterization of Circulating Epithelial and Endothelial Cells in Gougerot-Sjögren Syndrome, Compared to Systemic Sclerosis (CIRCEE)

Primary Gougerot-Sjögren Syndrome | Systemic Sclerosis, Diffuse

France
Peking University First Hospital

Recruiting

TreAtments and outComes in paTients With prImary CutAneous Lymphoma (TACTICAL)

Primary Cutaneous Lymphoma

China
Federal Research Institute of Pediatric Hematology...

Recruiting

B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021

Burkitt Lymphoma | Diffuse Large B-cell Lymphoma | Primary CNS Lymphoma | Primary Mediastinal Lymphoma | Non-hodgkin Lymphoma,B Cell

Russian Federation
First Affiliated Hospital, Sun Yat-Sen University

Recruiting

Clinical Study of Rituximab Combined With Corticosteroids or Rituximab Monotherapy in the Treatment of Primary Membranous Nephropathy

Primary Membranous Nephropathy

China
KalVista Pharmaceuticals, Ltd.

Recruiting

PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial

Hereditary Angioedema

United States, Bulgaria, France, Greece, Israel, Netherlands, Spain, United Kingdom, Australia, Germany, South Africa, Slovakia, Austria, New Zealand, Romania, Canada, Japan
Aesculap AG
Raylytic GmbH

Recruiting

In-vivo Wear Behaviour of AS Coated Versus Uncoated Columbus® Total Knee Prosthesis (COLRAS)

Knee Osteoarthritis | Osteonecrosis | Knee Arthritis | Instability, Joint | Rheumatoid Arthritis of Knee | Deformity Knee | Primary Osteoarthritis of Knee Nos | Secondary Osteoarthritis of Knee Nos

Australia, Germany
Takeda

Recruiting

A Survey of Icatibant in Pediatric Participants With Hereditary Angioedema

Hereditary Angioedema (HAE)

Japan
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

TTI-622 and TTI-621 in Combination With Pembrolizumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent Diffuse Large B-Cell... and other conditions

United States
KalVista Pharmaceuticals, Ltd.

Recruiting

An Open-label Extension Trial to Evaluate the Long-term Safety of KVD900 for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)

Hereditary Angioedema

United States, Bulgaria, France, Greece, Hungary, Israel, Italy, Netherlands, New Zealand, North Macedonia, Poland, Spain, United Kingdom, Australia, Germany, South Africa, Austria, Portugal, Slovakia, Romania, Canada, Saudi Arabia, Japa...
University of Regina
University of Saskatchewan; Saskatchewan Health Research Foundation; First Steps...

Recruiting

Exercise Effects in Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Chronic Progressive | Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

Canada
Takeda

Recruiting

A Study in Adults With Hereditary Angioedema (HAE) Who Currently Receive Icatibant at Home

Hereditary Angioedema (HAE)

United Kingdom
Brigham and Women's Hospital

Recruiting

Longitudinal Tracking of Patients Diagnosed With Neurodegenerative Movement Disorders

Synucleinopathies | Neurodegenerative Diseases | Ataxia | sca3 | MSA - Multiple System Atrophy

United States
Alfred Chung, MD
AbbVie; Janssen Pharmaceuticals

Recruiting

Venetoclax, Daratumumab, and Dexamethasone for Systemic Light-Chain Amyloidosis With Translocation (11;14) (ALTITUDE)

AL Amyloidosis | Light Chain (AL) Amyloidosis | Systemic Light Chain Disease

United States
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of GNC-038, a Tetra-specific Antibody, in Patients With Central Nervous System Lymphoma (PCNSL) and Relapsed or Refractory Secondary Central Nervous System Lymphoma (SCNSL)

Primary Central Nervous System Lymphoma | Secondary Central Nervous System Lymphoma

China
Second Xiangya Hospital of Central South University

Recruiting

The Associations of Psychological Stress With Therapy Efficacy and Prognosis of Lung Cancer (STRESS-LUNG)

Lung Cancer | Cancer, Treatment-Related | Psychological Stress | Immune Checkpoint Inhibitors

China
Dren Bio
Novotech

Recruiting

A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas

Aggressive NK Cell Leukemia | Hepatosplenic T-cell Lymphoma | Enteropathy-Associated T-Cell Lymphoma | Subcutaneous Panniculitis-Like T-Cell Lymphoma | Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma | LGLL - Large Granular Lymphocytic Leukemia | Primary Cutaneous T-Cell Lymphoma - Category and other conditions

United States, Australia, France, Spain
Hopital Foch
Siemens Healthcare QT

Recruiting

A Prospective Monocentric Study to Assess the Concordance of Lung MRI Compared to Chest CT Scan to Assess the Extent and Severity of Bronchial and Parenchymal Pulmonary Lesions in Adult Patients With Primary Immune Deficiency (PID) . (IRMvsSCANNER)

Primary Immune Deficiency

France
Allergy Therapeutics

Recruiting

Phase I Trial to Evaluate VLP Peanut in Healthy and Peanut Allergic Subjects (PROTECT)

Peanut Allergy

United States
Therapeutic Advances in Childhood Leukemia Consortium

Recruiting

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Lymphoma, B-Cell | Hodgkin Lymphoma | Lymphoblastic Lymphoma | Lymphoma, T-Cell | AML | Hematologic Malignancy | MDS | Acute Undifferentiated Leukemia | ALL | Mixed Phenotype Acute Leukemia | BPDCN

United States, Australia
Willows Health
Nottingham Trent University

Not yet recruiting

Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) (BRANCH-P)

Depression | Heart Diseases | Cardiovascular Diseases | HIV Infections | Obesity | Diabetes | Cancer | Chronic Kidney Diseases | Arthritis | Bulimia | Alzheimer Disease | Cellulitis | Cirrhosis | Eczema | Osteoporosis | Appendicitis | Bronchitis | Bowel Disease | Gout | Alcoholic Liver Disease | Flu | High Cholesterol | Allergies | Indigestion | ... and other conditions

United Kingdom
Takeda

Recruiting

A Study of Lanadelumab in Teenagers and Adults With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

United Kingdom
Sohag University

Not yet recruiting

The Expression of Immune Checkpoint CD28 rs1980422-related Single-nucleotide Polymorphisms in the Primary Immune Thrombocytopenia

Immune Thrombocytopenia

Egypt
Brigham and Women's Hospital
Massachusetts General Hospital

Recruiting

Feasibility of [11C]Acetate-PET in LAM and TSC

Tuberous Sclerosis Complex | Lymphangioleiomyomatosis

United States
AUG Therapeutics

Recruiting

A Study to Evaluate Efficacy and Safety of AVTX-803 in Patients With Leukocyte Adhesion Deficiency Type II

Leukocyte Adhesion Deficiency

United States
AC Immune SA
Worldwide Clinical Trials

Recruiting

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

Alzheimer's Disease | Prodromal Alzheimer's Disease | Amyloid Plaque | Beta-Amyloid | Alzheimer's Disease in Down Syndrome

United States, Spain, United Kingdom
Peking University People's Hospital

Not yet recruiting

Combined Steroid and Cyclosporin as First-line Treatment in Adults With Primary Immune Thrombocytopenia

Immune Thrombocytopenia

China
Children's Oncology Group

Recruiting

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Mixed Phenotype Acute Leukemia

United States, Australia, Canada
ANRS, Emerging Infectious Diseases
Saint-Louis Hospital, Paris, France; Hôpital Cochin; Bichat Hospital

Not yet recruiting

Immunity to Yellow Fever in HIV-infected Patients 10 Years After a Primary Anti-yellow Fever Vaccination

HIV Infections | Yellow Fever

Search clinical trials for: primary immune deficiencies

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