Search clinical trials for: mitochondrial DNA depletion syndrome

Total 45183 results

Pfizer

Completed

An Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Otsuka America Pharmaceutical

Completed

A Phase I Study of Three Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons With CD4+ Cell Number > 300 Cells/mm3

HIV Infections

United States
Hoffmann-La Roche

Completed

A Randomized, Parallel Arm, Comparative, Open Label, Multicenter Study of the Activity and Safety of Two Formulations of Saquinavir in Combination With Other Antiretroviral Drugs

HIV Infections

Canada, United States
Gilead Sciences

Unknown

Safety and Effectiveness of Adding Adefovir Dipivoxil and Nelfinavir to the Anti-HIV Therapy of HIV-Infected Children

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Large Intestine in Patients With AIDS

HIV Infections | Colitis

United States
Ortho Pharmaceuticals

Completed

The Safety and Effectiveness of r-HuEPO in Patients With AIDS and Anemia Caused by AIDS and Treatment With AZT

HIV Infections | Cytopenias

United States
Boehringer Ingelheim

Completed

The Safety and Effectiveness of Nevirapine and Zidovudine, Given Separately and Together, in HIV-1 Infected Patients Who Have No Symptoms of the Disease

HIV Infections

United States
Rockefeller University

Completed

A Study of Thalidomide in HIV-Infected Patients Who Are Receiving HAART

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Study of Two Anti-HIV Drug Combinations in HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Completed

Safety and Effectiveness of Tenofovir Disoproxil Fumarate (Tenofovir DF) Plus Other Anti-HIV Drugs in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
Amgen

Completed

Evaluation of the Therapeutic Benefit of r-metHuIFN- Gamma in AIDS Patients With Disseminated Mycobacterium Avium-Intracellulare (MAI) Infection: A Multi-Centered Pilot Study

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Merck Sharp & Dohme LLC

Completed

A Multicenter, Open-Label, Randomized, 24-Week Study to Compare the Safety and Activity of Indinavir Sulfate, 800 Mg q 8 h Versus 1,200 Mg q 12 h in Combination With Zidovudine and 3TC

HIV Infections

United States
Triangle Pharmaceuticals

Unknown

A Comparison of Emtricitabine and Stavudine Used With Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico, Canada, Argentina, Chile, Mexico
Merck Sharp & Dohme LLC

Completed

The Safety and Effectiveness of Indinavir Sulfate Plus Efavirenz

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Study of Capravirine Plus VIRACEPT Plus Two Nucleoside Reverse Transcriptase Inhibitors in HIV-Infected Patients Who Failed Previous Anti-HIV Treatments

HIV Infections

United States
Walter Reed Army Institute of Research (WRAIR)

Unknown

HIV Candidate Vaccine, ALVAC-HIV-1, Administration in HIV-Negative Adults

HIV Infections | HIV Seronegativity

United States
VA Medical Center-Gainesville

Completed

Diethylhomospermine (DEHSPM) for Refractory AIDS-Related Diarrhea

HIV Infections | Diarrhea

United States
Astra USA

Completed

Phase III Multicenter, Open-Label, Randomized Trial of Induction Versus Induction Plus Maintenance Foscarnet ( Foscavir ) Therapy for Gastrointestinal CMV Disease

Gastrointestinal Diseases | HIV Infections

United States
OXO Chemie

Completed

A Study to Evaluate the Safety and Effectiveness of WF10 Given to Patients With Late-Stage HIV Disease

HIV Infections

Canada, United States
Hoffmann-La Roche

Completed

Dideoxycytidine ( Ro 24-2027 ). A Treatment Protocol for the Use of Dideoxycytidine ( ddC ) in Patients With AIDS or Advanced ARC Who Cannot Be Maintained on Zidovudine ( AZT ) Therapy.

HIV Infections

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase III Randomized, Controlled Study of Ganciclovir for Symptomatic Congenital Cytomegalovirus Infection

Cytomegalovirus Infections
National Institute of Allergy and Infectious Diseases...

Terminated

A Study of Two Methods of Determining When to Begin or Change Anti-HIV Treatment

HIV Infections

United States
Glaxo Wellcome

Completed

A Phase II Open Randomized Comparison of 566C80 and Pentamidine Isethionate for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients Who Are Intolerant of Trimethoprim / Sulfamethoxazole

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Agouron Pharmaceuticals

Suspended

Safety and Effectiveness of a New Anti-HIV Drug (AG1549) in Combination With Other Anti-HIV Drugs in HIV-Infected Patients

HIV Infections

United States, Dominican Republic
Pfizer

Completed

Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal Meningitis

HIV Infections | Meningitis

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Trial To Evaluate the Safety and Immunogenicity of the UBI HIV-1MN PND Peptide Immunogen, Given by IM Injection, in Combination With the UBI Microparticulate Monovalent HIV-1 MN Branched Peptide Given Orally, in HIV-1 Uninfected Volunteers.

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Study of L-735,524 in HIV-Positive Children and Adolescents

HIV Infections

United States
Amgen

Completed

The Effects of r-metHuIFN-Gamma on the Lungs of Patients With AIDS

HIV Infections

United States
National Center for Research Resources (NCRR)

Completed

Parental Knowledge and Beliefs About Infant Sleep Position

Sudden Infant Death Syndrome
University of Rochester

Completed

Parallel Group, Placebo-Controlled, Tolerability, Safety, and Efficacy Study of OPC-14117 in HIV Dementia

HIV Infections | Cognitive Disorders

United States
Hoffmann-La Roche

Completed

A Study of Valganciclovir in the Treatment of Cytomegalovirus (CMV) Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
National Center for Research Resources (NCRR)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Establishment of the National Epidermolysis Bullosa Registry

Epidermolysis Bullosa
National Center for Research Resources (NCRR)
Indiana University School of Medicine

Unknown

Study of Systemic Amyloidosis Presentation and Prognosis

Amyloidosis

United States
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Multicenter Study of Nontuberculous Mycobacteria in Cystic Fibrosis Patients

Cystic Fibrosis | Atypical Mycobacterium Infection
Glaxo Wellcome

Unknown

Comparison of GW433908/Ritonavir to Nelfinavir When Used With Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs

HIV Infections

United States
Gilead Sciences

Completed

A Compassionate Use Study of Tenofovir Disoproxil Fumarate as Treatment for HIV Infection

HIV Infections

United States
Pfizer

Completed

A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDS

HIV Infections | Meningitis, Cryptococcal

United States
Hoffmann-La Roche

Completed

An Open-Label Safety Program for the Use of Zalcitabine (Dideoxycytidine; ddC) in Pediatric Patients With Symptomatic HIV Infection Who Have Failed or Are Intolerant to AZT Monotherapy, or Who Have Completed Other ddC Protocols, or Are Ineligible for Other Ongoing Clinical Studies

HIV Infections

United States
Agouron Pharmaceuticals

Unknown

Effectiveness of Treating HIV-Positive Patients With an HIV Vaccine (Remune)

HIV Infections

United States
National Center for Research Resources (NCRR)
Children's Hospital of Philadelphia

Completed

Study of the Pathobiology of Bronchopulmonary Dysplasia in Newborns

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia

United States
Glaxo Wellcome

Completed

An Oral Dose-Ranging Finding Study in Patients With HIV Disease, CDC Classification Groups IIB, III, and IV-C2

HIV Infections

United States
Gilead Sciences

Completed

A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected Patient

HIV Infections

United States, Puerto Rico
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Two Forms of Saquinavir Combined With Other Anti-HIV Drugs in HIV-Infected Infants and Children

HIV Infections

United States
Glaxo Wellcome

Completed

An Open-Label, Uncontrolled Clinical Trial of Oral 566C80 for the Treatment of Patients With Severe PCP Who Are Intolerant and/or Unresponsive to Therapy With Trimethoprim/Sulfamethoxazole and Parenteral Pentamidine

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Glaxo Wellcome

Completed

A Phase I Trial to Evaluate the Safety, Pharmacokinetics and Antiviral Activity of 141W94 After Multiple Dosing in Patients With HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of 1592U89 in HIV-Infected Patients

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Combination Treatment Using Capravirine (AG1549), Nelfinavir, and Two Nucleoside Reverse Transcriptase Inhibitors in HIV Patients Who Failed Initial Combination Therapy

HIV Infections

United States, Puerto Rico
National Center for Research Resources (NCRR)
University of Pittsburgh

Terminated

Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency

Alpha 1-Antitrypsin Deficiency

United States
The Dana Foundation

Completed

A Study of Thioctic Acid and Deprenyl in HIV-Infected Patients With Dementia

HIV Infections | Cognitive Disorders

United States
Neurex

Completed

A Multicenter Phase II/III, Placebo-Controlled Study of SNX-111 Administered Intrathecally to Cancer and AIDS Patients With Chronic Pain

HIV Infections | Pain | Cancer

United States

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