Search clinical trials for: AMG 108

Total 7234 results

Splash Pharmaceuticals, Inc.

Unknown

Safety and Efficacy Study of Daily SPL-108 Injections In Conjunction With Paclitaxel in Women With Ovarian Cancer

Ovarian Epithelial Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma | Stage IV Osteosarcoma AJCC v7 | Stage IVA Osteosarcoma AJCC v7 | Stage IVB Osteosarcoma AJCC v7 | Metastatic Osteosarcoma

United States, Canada, Puerto Rico
Epicentre
Médecins Sans Frontières, France; Embassy of France in Uganda; National Sleeping...

Terminated

Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis

Trypanosomiasis, African

Uganda
Columbia University
National Institute on Aging (NIA)

Completed

Comparison of AVF Versus AVG in Elderly Patients Starting Dialysis

Chronic Kidney Disease | Endstage Renal Disease

United States
Green Cross Corporation
Symyoo

Completed

GCPGC in Chemotherapy-induced Neutropenia

Chemotherapy Induced Neutropenia

Korea, Republic of
Ono Pharmaceutical Co. Ltd

Terminated

A Study of ONO-7475 in Patients With Acute Leukemias

Myelodysplastic Syndromes | Acute Leukemia

United States
Cytokinetics

Completed

Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction (GALACTIC-HF)

Heart Failure

United States, Belgium, Canada, Denmark, France, Italy, Netherlands, United Kingdom, Hungary, Colombia, Mexico, Poland, Russian Federation, Switzerland, Czechia, Turkey, China, Spain, Australia, New Zealand, Chile, Austria, Slovakia, ... and more
Peking Union Medical College Hospital
National Institute for Biomedical Imaging and Bioengineering (NIBIB)

Unknown

177Lu-EB-PSMA617 in Patients With Metastatic Castration-resistant Prostate Cancer

Metastatic Castration-resistant Prostate Cancer

China
M.D. Anderson Cancer Center
Amgen

Withdrawn

Trastuzumab in Combination With AMG 479 in HER-2 Overexpressing MBC Progressing on Trastuzumab

Breast Cancer
Amgen

Completed

Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only

Bone Metastases in Men With Hormone-Refractory Prostate Cancer | Bone Metastases in Subjects With Advanced Breast Cancer | Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma

United Kingdom, Czech Republic
Amgen

Completed

AMG 102 Plus ECX for Unresectable Locally Advanced or Metastatic Gastric or Esophagogastric Junction Cancer

Gastric Cancer | Esophageal Cancer | Esophagogastric Junction Adenocarcinoma
Amgen

Completed

AMG 386, 20060159 Phase 2, RCC 1st Line in Combination With Sorafenib

Advanced Renal Cell Carcinoma
Assiut University

Recruiting

Peroneal Nerve Dysfunction in Epiphyseal Transfer

Epiphyseal Arrest

Egypt
Newave Pharmaceutical Inc

Active, not recruiting

Dose-Escalation Study of Oral Administration of LP-108 as Monotherapy and in Combination With Azacitidine in Patients With Relapsed or Refractory MDS, CMML, or AML

Refractory Acute Lymphoblastic Leukemia | Relapse | CMML | Relapsed Adult AML | AML/MDS | Relapse Leukemia

United States, Spain
HK inno.N Corporation

Unknown

A Phase 2 Dose Selection Trial of Candesartan Cilexetil and Amlodipine Besylate to Treat Essential Hypertension

Essential Hypertension

Korea, Republic of
Nottingham University Hospitals NHS Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; Manchester... and other collaborators

Recruiting

A Comprehensive Approach To Relief Of Digestive Symptoms In Cystic Fibrosis: CARDS-CF (CARDS-CF)

Respiratory Tract Diseases | Lung Diseases | Cystic Fibrosis | Genetic Disease | Digestive System Disease | Pancreatic Disease

United Kingdom
i-Lumen Scientific, Inc.

Recruiting

Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT) (i-SIGHT)

Age-Related Macular Degeneration | Dry Age-related Macular Degeneration | Nonexudative Age-related Macular Degeneration

United States
Wake Forest University Health Sciences

Completed

FGF23 and Angiotensin-(1-7) in Hypophosphatemia (GAP) (GAP)

Hypophosphatemia | X-linked Hypophosphatemia | Left Ventricular Hypertrophy | Renin-angiotensin System

United States
Bayer

Completed

Evaluation of the Stinging Potential of Sunscreen Products in Human Eyes

Sunscreen Agents

United States
University Hospital, Angers

Completed

VASO-AM :Impact of Oral Appliance Therapy on Endothelial Function in Obstructive Sleep Apnea (VASO-AM)

Obstructive Sleep Apnea Syndrome

France
Eisai Co., Ltd.

Completed

A Single-dose Study in Healthy Japanese Male Adults to Evaluate Pharmacokinetics and Pharmacodynamics of E5501 5 mg Tablet (Study E5501-J081-015)

Healthy

Japan
Amgen

Not yet recruiting

Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab (DeLLphi-305)

Small-Cell Lung Cancer | Extensive-Stage Small-Cell Lung Cancer
Pharmaxis

Completed

Mannitol Dose Response Study in Cystic Fibrosis

Cystic Fibrosis

Canada, Argentina
Sentient Research
Wayne State University; University of Mississippi Medical Center; AIDS Healthcare... and other collaborators

Not yet recruiting

Quantitative and Qualitative Research for "mHealth Program to Support People Living With HIV Across the HIV Care Continuum" (VSS)

HIV Infections

United States
Assiut University

Not yet recruiting

Abg in Blunt Chest Trauma

Blunt Injury of Thorax
Mayo Clinic

Completed

A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Metastatic... and other conditions

United States
Abbott

Completed

A Comparison of the Safety and Efficacy of Cefdinir Oral Suspension Versus Amoxicillin/Clavulanate in Pediatric Subjects With Acute Otitis Media

Acute Otitis Media

United States
American Medical Systems

Completed

Evaluation of the 2005 AMS (American Medical System) IPP (Inflatable Penile Prosthesis)

Erectile Dysfunction

United States
M.D. Anderson Cancer Center
Amgen

Terminated

Denosumab for Breast Cancer With Bone Mets

Breast Cancer

United States
Amgen

Completed

Multiple Dose Study to Evaluate the Safety of Multiple Doses of Denosumab 120 mg in Adults With Severe Chronic Kidney Disease (CKD) and CKD on Dialysis

Renal Impairment

United States
Amgen

Completed

Safety Study of AMG 386 to Treat HER2-positive Locally Recurrent or Metastatic Breast Cancer

Cancer | Breast Cancer | Breast Neoplasms | Metastatic Cancer | Breast Tumors | Solid Tumors | Oncology | Tumors | Metastases | Locally Recurrent and Metastatic Breast Cancer

United States, Belgium, France
ASTORA Women's Health

Completed

Pelvic Floor Repair Systems for Prolapse Repair (PROPEL)

Pelvic Organ Prolapse

United States, Belgium, France, Germany, Netherlands, Spain, United Kingdom
Amgen

Withdrawn

Safety Evaluation of Panitumumab and Sirolimus in Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer | Oncology
NuvOx LLC
The Alfred

Completed

The Effects of NVX-108 as a Radiation Sensitizer in Glioblastoma (GBM)

Glioblastoma Multiforme

Australia
Pfizer

Completed

A 12 Week Study to Confirm the Effectiveness of 8mg of Fesoterodine Compared to 4mg of Fesoterodine

Overactive Bladder

Korea, Republic of, United States, Denmark, Germany, Canada, Hungary, Poland, France, United Kingdom, Slovakia, Sweden, Mexico, Czech Republic, Finland, Italy, Lithuania, Argentina, Chile, Colombia, Egypt, Greece, Norway, Philippines, Russian Federation and more
Vigonvita Life Sciences

Completed

Pharmacodynamic Study of TPN171H Tablets in Patients With Mild to Moderate Erectile Dysfunction

Erectile Dysfunction

China
Allegro Ophthalmics, LLC

Completed

A Safety And Efficacy Study Of ALG-1001 In Human Subjects With Wet Age-Related Macular Degeneration

Macular Degeneration

Mexico
Beijing Immunochina Medical Science & Technology...

Not yet recruiting

Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors

Melanoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

China
Amgen

Completed

Phase 2 AMG 386 in Comb. Paclitaxel for Subjects With Advanced Recurrent Epithelial Ovarian or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer
Fujian Medical University

Enrolling by invitation

Clinical Outcomes of Robotic Versus Laparoscopic Assisted Radical Gastrectomy for Advanced Siewert II/III AEG

Esophagogastric Junction Adenocarcinoma

China
Amgen

Completed

Extension Study to Evaluate the Long Term Safety and Efficacy of Denosumab in the Treatment of Osteoporosis

Osteoporosis | Osteopenia
Amgen

Completed

AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Androgen-Deprivation Therapy for Non-metastatic Prostate Cancer

Prostate Cancer
Amgen

Completed

An Open-label, Single-arm Extension Study to Evaluate the Long-term Safety of Denosumab Administration in Postmenopausal Women With Low Bone Mineral Density

Low Bone Mineral Density
Amgen

Completed

Safety and Efficacy Study of Romiplostim to Treat Immune Thrombocytopenia (ITP) in Pediatric Patients

Thrombocytopenia | Immune Thrombocytopenia | Idiopathic Thrombocytopenic Purpura | Thrombocytopenia in Pediatric Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | Thrombocytopenic Purpura

United States, Canada, Australia
Sanko University

Recruiting

The Relationship Between Lumbar Disc Herniation and Urinary Incontinence

Lumbar Disc Herniation

Turkey
Elizabeth J Franzmann
Aveta Biomics, Inc.

Recruiting

A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia

Oropharyngeal Dysplasia | Oral Cavity Dysplasia | Oral Carcinoma in Situ

United States
Multitude Therapeutics Inc.

Recruiting

AMT-116 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Australia
Ascentage Pharma Group Inc.

Recruiting

Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or Lymphomas

Sarcoma | Nasopharyngeal Carcinoma | Gastric Cancer | B Cell Lymphoma | Mesothelioma | Non Hodgkin Lymphoma | Ovarian Clear Cell Carcinoma | Epithelioid Sarcoma | Castrate Resistant Prostate Cancer

United States
Vivostat
European Commission; Raffeiner GmbH; AF Schimetta GMbH; Rivolution GmbH

Recruiting

Investigation of the Benefit of Using an Autologous Platelet-rich Fibrin Matrix (Obsidian ASG®) for Treatment of Anastomosis During Rectal Surgery (ORSY)

Anastomotic Leak Rectum

Belgium, Germany, Spain, Austria, Denmark, Italy, Serbia
Centennial Medical Center

Recruiting

Delirium Reduction With Ramelteon (DREAM)

Delirium

United States

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