Clinical Trials Sponsored by Picker Institute

Total 74834 results

Istituto Scientifico H. San Raffaele

Unknown

Hydroxyurea With or Without Imatinib Mesylate in Treating Patients With Recurrent or Progressive Meningioma

Brain and Central Nervous System Tumors

Italy
Istituto Scientifico H. San Raffaele

Unknown

Study of Blood and Tissue Samples in Predicting Response to Second-Line Therapy Using Erlotinib Hydrochloride or Chemotherapy in Patients With Advanced Non-Small Cell Lung Cancer

Lung Cancer

Italy
Assistance Publique - Hôpitaux de Paris
Institut Pasteur; Recherche Clinique Paris Descartes Necker Cochin Sainte Anne and other collaborators

Recruiting

Research Trial Assessing the Immunogenicity and Safety of Three Meningococcal B Vaccine Strategies Among Patients With Asplenia. (SPLEMENGO)

Splenectomy

France
Istituto Giannina Gaslini
Bambino Gesù Hospital and Research Institute

Recruiting

Rituximab Versus Mycophenolate Mofetil in Children With Steroid-dependent Idiopathic Nephrotic Syndrome. (RTXvsMMF)

Nephrotic Syndrome Steroid-Dependent

Italy
Children's National Research Institute
National Institute of Nursing Research (NINR); National Institutes of Health... and other collaborators

Active, not recruiting

FACE for Children With Rare Diseases (FACE-Rare)

Rare Diseases

United States
OHSU Knight Cancer Institute
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Terminated

Imaging of Intravenous (IV) Combidex to Brain, Intra-cerebral Tumors and in Central Nervous System (CNS) Inflammation

Brain Neoplasms

United States
National Cancer Institute (NCI)
Finnish Institute for Health and Welfare

Completed

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

Stroke | Diabetes Mellitus | Cancer | Heart Disease

Finland
National Eye Institute (NEI)
National Human Genome Research Institute (NHGRI)

Completed

Nitisinone for Type 1B Oculocutaneous Albinism

Albinism | Vision Loss

United States
OHSU Knight Cancer Institute
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Terminated

Neurotoxicity in Primary Central Nervous System Lymphoma (PCNSL): An International Observational Study of Cognition in Long Term Survivors

Primary Central Nervous System Lymphoma (PCNSL)

United States, Germany
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Vaccine Therapy, Tretinoin, and Cyclophosphamide in Treating Patients With Metastatic Lung Cancer

Lung Cancer

United States
PIQUR Therapeutics AG
Hospital Universitari Vall d'Hebron Research Institute; Institut Català d'Oncologia and other collaborators

Completed

PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)

Metastatic Breast Cancer

Spain, United Kingdom
National Cancer Institute (NCI)
National Institutes of Health (NIH)

Completed

Isolation and Characterization of Mammary Stem Cells

Stem Cells

United States
German Parkinson Study Group (GPS)
Philipps University Marburg Medical Center; MSE Pharmazeutika GmbH, Louisenstr... and other collaborators

Completed

Study About Safety and Efficacy of Coenzyme Q10 in Progressive Supranuclear Palsy

Progressive Supranuclear Palsy

Germany
National Cancer Institute (NCI)

Not yet recruiting

A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer

Colorectal Cancer | Gastroesophageal Cancer

United States
National Cancer Institute (NCI)

Recruiting

Natural History Study of Kaposi Sarcoma

HIV | Kaposi Sarcoma

United States
National Cancer Institute (NCI)

Not yet recruiting

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

Glioma | Astrocytoma | Recurrent Glioblastoma

United States
National Cancer Institute (NCI)

Recruiting

Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)

Small Cell Carcinoma of the Bladder | High Grade Neuroendocrine Tumors of the Urinary Tract

United States
National Cancer Institute (NCI)

Recruiting

Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors

Locally Advanced Chondrosarcoma | Metastatic Chondrosarcoma | Metastatic Sinonasal Adenocarcinoma | Locally Advanced Sinonasal Adenocarcinoma | Metastatic Large-cell Neuroendocrine Carcinoma | Locally Advanced Large-cell Neuroendocrine Carcinoma | Metastatic Olfactory Neuroblastoma | Locally Advanced... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

Glioma | Ependymoma | Medulloblastoma

United States
National Cancer Institute (NCI)

Not yet recruiting

Erlotinib in Combination With Select Tyrosine Kinase Inhibitors in Adult Patients With Advanced Solid Tumors

Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

18F-Fluciclovine PET/CT in Multiple Myeloma

Multiple Myeloma | Relapsed and/or Refractory Multiple Myeloma (RRMM) | Newly Diagnosed Multiple Myeloma (NDMM)

United States
National Cancer Institute (NCI)

Recruiting

Enzalutamide and M9241 in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy

Recurrent Prostate Cancer | Prostate Cancer | PET Positive

United States
National Cancer Institute (NCI)

Not yet recruiting

Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)

KSHV Inflammatory Cytokine Syndrome (KICS) | Kaposi Sarcoma Herpesvirus -Associated Multicentric Castleman Disease

United States
National Cancer Institute (NCI)

Recruiting

Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors and Carcinomas

Neuroendocrine Tumors | Carcinoma, Neuroendocrine | Neuroendocrine Carcinomas | Carcinoma, Adrenal Cortical | Carcinoma, Adrenocortical

United States
National Cancer Institute (NCI)

Recruiting

Pilot Prospective Study for PET-CT Imaging in Participants With Relapsed/Refractory Acute Leukemias

Acute Lymphoblastic Leukemia | Relapsed/Refractory | B Cell

United States
National Cancer Institute (NCI)

Recruiting

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

Mesothelioma | BRCA1-Associated Protein-1 (BAP1) Mutations | Malignant Mesothelioma (MM) | Early-stage Mesothelioma | Subclinical Mesothelioma | Early-stage BAP1-associated Malignancies

United States
National Cancer Institute (NCI)

Recruiting

Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States
National Cancer Institute (NCI)

Recruiting

Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer

Neoplasms | Esophageal Neoplasms | Esophagus Cancer | Esophagus Neoplasm | Neoplasms, Esophageal | Esophageal Cancer (EsC)

United States
National Cancer Institute (NCI)

Recruiting

Study of Rates of Prostate Cancer Diagnosis in Men of African Ancestry Using MRI and MRI Guided Biopsy

Prostatic Neoplasms | Prostate Specific Antigens | Positive Digital Rectal Examination | Strong Family History of Prostate Cancer

United States
National Cancer Institute (NCI)

Recruiting

Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies

Lymphoma, B-Cell | Chronic Lymphocytic Leukemia | B-Cell Chronic Lymphocytic Leukemia

United States
National Cancer Institute (NCI)

Recruiting

Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-small Cell Lung Cancer

Advanced Non Small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Recruiting

Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Non-Small Cell Lung Cancer | Non-Small Cell Lung Carcinoma | Carcinomas

United States
National Cancer Institute (NCI)

Recruiting

Study of Zotiraciclib for Recurrent High-Grade Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Cancer | Brain Tumor

United States
National Cancer Institute (NCI)

Recruiting

Prospective Monitoring of Subjects With Biochemically Recurrent Prostate Cancer Using 18FDCFPyL

Prostate Cancer | Biochemically Recurrent

United States
National Cancer Institute (NCI)

Recruiting

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Peripheral Blood Stem Cell Transplantation

United States
National Cancer Institute (NCI)

Recruiting

Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis

Glioma

United States
National Cancer Institute (NCI)

Recruiting

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

Burkitt Lymphoma | Plasmablastic Lymphoma | Non-Hodgkin Lymphoma | Diffuse Large Cell Lymphoma | B-Cell Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial

Neurofibromatosis 1 | Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Rare Tumors and Cancer Predisposition in Individuals and Families

Cancer | Hereditary Neoplasms | Genetic Predisposition to Cancer | Environment

United States
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Colorectal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bile Duct Neoplasms | Metastatic Colorectal Cancer (Mcrc) | Intrahepatic Cholangiocarcinoma (Icc) | Intrahepatic Bile Duct Cancer

United States
National Cancer Institute (NCI)

Recruiting

Olaparib in Subjects With Advanced Pancreatic Acinar Cell Carcinoma

Pancreatic Acinar Cell Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Small Bowel, Gastric, Cholangiocarcinoma, Breast, Ovarian, or Other Gynecologic Primary Cancer

Gynecologic Cancer | Colorectal Neoplasms | Colorectal Cancer | Ovarian Neoplasms | Peritoneal Neoplasms | Ovarian Cancer | Peritoneal Carcinomatosis | Appendiceal Neoplasms | Appendiceal Cancer | Gynecologic Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

Metastatic Renal Cell Carcinoma | Metastatic Melanoma | Advanced Locoregional Melanoma | Clear Cell Histology

United States
National Cancer Institute (NCI)

Recruiting

Hyperspectral Analysis of Sweat Metabolite Biometrics for Real-Time Detection of COVID-19

COVID-19

United States
National Cancer Institute (NCI)

Recruiting

GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma | Hepatocellular Cancer | Metastatic Hepatocellular Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

Hematologic Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma

Kaposi Sarcoma

United States
Stanford University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Clinical Trial of a Novel Small Molecule EBNA1 Inhibitor, VK 2019, in Patients With Epstein Barr Virus (EBV)-Positive Nasopharyngeal Cancer (NPC) and Other Epstein-Barr Virus (EBV)-Associated Cancers, With Pharmacokinetic and Pharmacodynamic Correlative Studies

Nasopharyngeal Cancer | Epstein-Barr Virus Related Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies

Urogenital Neoplasms | Bladder Cancer | Urothelial Cancer | Genitourinary Cancer | Urogenital Cancer

United States
National Cancer Institute (NCI)

Recruiting

Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV

Kaposi Sarcoma | Viral Associated Malignancies | EBV/KSHV-associated Lymphomas

United States

Clinical Trials Sponsored by Picker Institute

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Spain

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations