Search clinical trials for: Aged

Total 2103 results

Janssen Research & Development, LLC

Active, not recruiting

A Study of 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) and High-dose Quadrivalent Influenza Vaccine, With and Without Co-administration, in Adults Aged 65 Years or Older (Engage)

Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention

United States, Poland, Belgium, Canada
University of Exeter

Active, not recruiting

The Impact of Energy Intake and Short-term Disuse on Muscle Protein Synthesis Rates and Skeletal Muscle Mass in Middle-aged Adults. (PIE)

Aging | Muscle Atrophy | Energy Malnutrition Protein

United Kingdom
Purdue University
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Retrieval-Based Word Learning in Developmental Language Disorder

Language Development | Developmental Language Disorder | Specific Language Impairment

United States
Universidad de Concepcion

Enrolling by invitation

Active Breaks on Mental Health and Classroom Climate in Chilean Schoolchildren Aged 6 to 10

Mental Health | School Health | School-age Children

Chile
GlaxoSmithKline

Completed

A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 50-59 Years of Age, Including Adults at Increased Risk of Respiratory Syncytial Virus Lower Respiratory Tract Disease, Compared to Older Adults 60 Years of Age and Above

Respiratory Syncytial Virus Infections

Argentina, United States, Germany, Spain, Poland, Canada, Japan, Netherlands
AstraZeneca

Active, not recruiting

A Study to Investigate Efficacy and Safety of Ceralasertib Plus Durvalumab in Participants Aged ≥ 18 Years With Advanced or Metastatic Non-small Cell Lung Cancer Whose Disease Progressed on or After Prior Anti-PD-(L)1 Therapy and Platinum-based Chemotherapy (LOTOS)

Advanced or Metastatic NSCLC

Russian Federation
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN (SPRINKLE)

Neurofibromatosis Type 1

United States, Spain, Germany, Netherlands, Russian Federation, Italy, Japan
University of Oulu
Lapland Central Hospital Rovaniemi Finland

Completed

Efficacy and Safety of E-cigarettes for Smoking Cessation in Middle-aged Heavy Smokers (EFFECT)

Smoking Cessation | Electronic Cigarette

Finland
Duke University
National Institute on Aging (NIA)

Completed

Deprescribing for Older Dialysis Patients

Kidney Failure, Chronic

United States
Hoffmann-La Roche

Terminated

A Study to Evaluate the Safety and Efficacy of Basmisanil Treatment in Children Aged 2-14 Years With Dup15q Syndrome

Dup15q Syndrome

United States, Spain, United Kingdom, Poland, Portugal
Takeda

Completed

A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older

Short Bowel Syndrome

Japan
Janssen Vaccines & Prevention B.V.

Terminated

A Study of an Ad26.RSV.preF-based Regimen in the Prevention of Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)-Confirmed Respiratory Syncytial Virus (RSV)-Mediated Lower Respiratory Tract Disease in Adults Aged 65 Years and Older (CYPRESS)

Respiratory Tract Diseases | Respiratory Syncytial Viruses

United States
University of Americas

Enrolling by invitation

Slow Gait Speed as an Indicator of Overweight, Dynapenic Obesity and Sarcopenic Obesity in Elderly People in the Community (SGSF)

Obesity | Frailty | Sarcopenia | Sarcopenic Obesity | Gait Speed

Chile
University of Exeter
University of Leeds; National Institute for Health Research, United Kingdom

Completed

Exploring 'VOLITION' in Context - a Study to Inform the Implementation of a New Intervention (VOLITION)

Aged | Multimorbidity | Decision Making | General Practice

United Kingdom
Hoffmann-La Roche

Active, not recruiting

A Study of Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Carcinoma (SKYSCRAPER-08)

Esophageal Cancer

Korea, Republic of, China, Hong Kong, Thailand, Taiwan
Hoffmann-La Roche

Active, not recruiting

A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer (SKYSCRAPER-04)

Cervical Cancer

Italy, Korea, Republic of, Canada, United States, Brazil, France, United Kingdom, Spain, Costa Rica, Russian Federation, Panama, Australia, Mexico, Peru, Poland, Taiwan, Thailand
Massachusetts General Hospital

Active, not recruiting

Text Messaging to Increase Activity in Midlife (MASTERY)

Middle Aged

United States
University of Colorado, Denver
Genentech, Inc.

Suspended

Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC

Squamous Cell Carcinoma of Head and Neck

United States
Hoffmann-La Roche
Latin American Cooperative Oncology Group

Active, not recruiting

A Study to Describe the Diagnosis, Anti-Cancer Treatment and Clinical Outcome in Patients With Newly Diagnosed Breast Cancer in Latin America

Breast Cancer

Colombia, Guatemala, Argentina, Brazil, Chile, Cuba, Mexico, Peru, Uruguay, Dominican Republic
Bayer

Active, not recruiting

A Study to Learn How Safe the Study Treatment BAY94-9027 is and How it Affects the Body in Previously Treated Children Aged 7 to Less Than 12 Years With Severe Hemophilia A, a Genetic Bleeding Disorder That is Caused by the Lack of a Protein Called Clotting Factor 8 (FVIII) in the Blood (Alfa-PROTECT)

Hemophilia A | Children | Prophylaxis of Bleeding | Treatment of Bleeding

Canada, United States, Brazil, Italy, Turkey, Argentina, Norway
Sanofi Pasteur, a Sanofi Company

Completed

Substudy 01 - Safety and Immunogenicity of One Monovalent Modified mRNA Vaccine Encoding Influenza Hemagglutinin With LNP, in Adult Participants Aged 18 to 49 Years and 60 Years and Above

Influenza Immunization

Australia, United Kingdom
University of Saskatchewan

Completed

Walking Aid Assessment, Arm Strength and Force Under the Foot in Normal Subjects

Adolescent | Healthy | Gait | Aged | Young Adult | Middle Age | Physical Examination

Canada
Universitaet Innsbruck
Tirol Kiniken GmbH

Active, not recruiting

TirolGESUND: Baseline-controlled Comparison of the Effects of Fasting Dietary Intervention or Smoking Cessation Combined With Exercise in Healthy Female Tyrolean Volunteers Aged 30-60 on Epigenetic and Multi-omic Biomarkers of Health, Ageing, and Disease (TirolGESUND)

Smoking Cessation | Healthy | Healthy Lifestyle | Intermittent Fasting

Austria
University of Texas at Austin
Boys & Girls Clubs of the Austin Area

Active, not recruiting

'Food, Fun, Fresh, Family' Program for Healthy Eating and Growth for Elementary-age Children. (FUEL)

Diet, Healthy Growth

United States
Liverpool John Moores University

Completed

Resistance Training and Hydrolyzed Collagen Supplementation in Middle-aged Adults

Diet | Nutrition | Food

United Kingdom
Hoffmann-La Roche

Completed

A Study of Biomarker-Driven Therapy in Metastatic Colorectal Cancer (mCRC) (MODUL)

Colorectal Cancer

Italy, Korea, Republic of, United Kingdom, Belgium, Argentina, Denmark, Greece, Netherlands, Slovenia, Spain, Sweden, Turkey, Brazil, Bosnia and Herzegovina, France, Germany, Portugal, Egypt, Poland, Slovakia, Mexico, Serbia, Russian...
Daiichi Sankyo
Daiichi Sankyo Korea Co., Ltd.

Active, not recruiting

An Observational Study Investigating the Change in Blood Cholesterol With Mevalotin® Tablet Administration in Korean Menopausal Women Aged 50 Years or More Who Require Treatment of Dyslipidemia

Dyslipidemia

Korea, Republic of
University Hospital, Grenoble
Genoscience Pharma

Terminated

Ezurpimtrostat Autophagy Inhibitor in Association With Atezolizumab-Bevacizumab in First Line Treatment of Unresectable Hepatocellular Carcinoma (ABE-LIVER)

Hepatocellular Carcinoma

France
Sanofi Pasteur, a Sanofi Company

Active, not recruiting

Study of a Respiratory Syncytial Virus Candidate Encapsulated in a Lipid Nanoparticle Based Formulation in Adults Aged 18 to 50 Years and 60 Years and Older

Respiratory Syncytial Virus Immunization

United States, Australia, Puerto Rico
Synlogic
IQVIA Biotech

Terminated

Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult Participants

Lymphoma | Metastatic Solid Neoplasm

United States
Genentech, Inc.

Active, not recruiting

A Safety, Efficacy and Pharmacokinetic Study of BTCT4465A (Mosunetuzumab) as a Single Agent and Combined With Atezolizumab in Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Lymphocytic Leukemia, Chronic | Lymphoma, Non Hodgkin

United States, Korea, Republic of, Australia, United Kingdom, Germany, Canada, Spain
Janssen Research & Development, LLC

Completed

A Study of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to <12 Years) Who Are Virologically Suppressed

HIV

Italy, Thailand, Spain, Uganda, Portugal, South Africa
Washington University School of Medicine
Eli Lilly and Company

Completed

Ramucirumab and Atezolizumab After Progression on Any Immune Checkpoint Blocker in NSCLC (RamAtezo-1)

NSCLC | Non Small Cell Lung Cancer | Non-small Cell Lung Cancer

United States
Chang-Ming Huang, Prof.

Completed

Model for Prognosis of Elderly Gastric Cancer Patients

Stomach Neoplasms | Aged

China
Genentech, Inc.

Active, not recruiting

A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer

United States, Spain, Korea, Republic of, Taiwan, France, Serbia
GlaxoSmithKline

Completed

A Study on the Reactogenicity, Safety and Immune Response of a Targeted Immunotherapy Against HSV in Healthy Japanese Participants Aged 18-40 Years (TH HSV REC-004)

Herpes Simplex

Japan
ETOP IBCSG Partners Foundation
Roche Pharma AG

Active, not recruiting

ABC-lung: Atezolizumab, Bevacizumab and Chemotherapy in EGFR-mutant Non-small Cell Lung Carcinoma (ABC-lung)

EGFRmutant Stage IIIB/C or IV Non-squamous NSCLC

Singapore, Spain, Korea, Republic of, Switzerland, Germany
Ipsen

Active, not recruiting

A Rollover Study to Further Evaluate the Safety and Efficacy of Palovarotene Capsules in Male and Female Participants Aged ≥14 Years With Fibrodysplasia Ossificans Progressiva (FOP) Who Have Completed the Relevant Parent Studies. (PIVOINE)

Fibrodysplasia Ossificans Progressiva (FOP)

United States, France, Australia, Argentina, Italy, Canada, Sweden, United Kingdom, Brazil, Spain
Hoffmann-La Roche

Active, not recruiting

A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy (SKYSCRAPER-07)

Esophageal Squamous Cell Carcinoma

United States, France, Spain, Australia, Korea, Republic of, Argentina, Belgium, China, Portugal, Taiwan, Japan, Germany, Poland, Thailand, United Kingdom, Switzerland, Turkey, Russian Federation, Morocco, Greece, Italy, New Zealand, South Africa and more
GlaxoSmithKline

Active, not recruiting

A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital Herpes

Herpes Simplex

Germany, United States, Belgium, Canada, Spain, United Kingdom, Estonia, Australia
Kristian Karstoft

Active, not recruiting

Winter-Swimming and Brown Adipose Tissue Activity in Middel-aged Obese Subjects (WinterBAT). (WinterBAT)

Obesity | Type 2 Diabetes Mellitus | Brown Adipose Tissue | Cold Exposure | Adipose Tissue, Brown | Uncoupling Protein 1 | Winter Swimming

Denmark
Genentech, Inc.
BioNTech SE

Active, not recruiting

A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Melanoma | Head and Neck Cancer | Colorectal Cancer | Non-Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | Renal Cancer | Other Solid Cancers

United States, Belgium, Sweden, Germany, Canada, Spain, United Kingdom, Netherlands
Janssen Research & Development, LLC

Active, not recruiting

A Study of Three Different Doses of VAC52416 (ExPEC10V) in Adults Aged 60 to 85 Years in Stable Health

Extraintestinal Pathogenic Escherichia Coli Prevention

United States, France, Belgium, Spain, Netherlands
Taipei Medical University

Completed

HIIT on Overweight Middle-aged Adults (HIIT)

Overweight or Obesity

Taiwan
Hoffmann-La Roche

Active, not recruiting

A Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer (IMpower030)

Non-Small-Cell Lung

United States, Korea, Republic of, United Kingdom, Australia, France, Italy, Spain, Japan, Brazil, China, Germany, Poland, Thailand, Israel, Switzerland, Taiwan, Austria, Russian Federation, Ukraine, Hungary, Serbia, Slovenia, South... and more
Hoffmann-La Roche

Terminated

A Study of Atezolizumab (Anti-Pd-L1 Antibody) as Adjuvant Therapy After Definitive Local Therapy in Patients With High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)

United States, Korea, Republic of, Canada, Australia, Russian Federation, United Kingdom, Belgium, Brazil, China, France, Italy, Portugal, Spain, Japan, India, Thailand, Ukraine, Taiwan, Poland, Turkey, Hungary, South Africa, Germany
Gustave Roussy, Cancer Campus, Grand Paris

Active, not recruiting

Trial Assessing the Inhibitor of Programmed Cell Death Ligand 1 (PD-L1) Immune Checkpoint Atezolizumab (ATEZOLACC)

Locally Advanced Cervical Cancer

France
Fundacion para la Investigacion Biomedica del Hospital...
Universitat Politècnica de València

Active, not recruiting

Impact of the Menstrual Cycle in Reproductive Aged Women With Type 1 Diabetes Using a Closed Loop System (DIABETEXX/1). (DIABETEXX/1)

Type 1 Diabetes

Spain
Pfizer

Active, not recruiting

Study to Evaluate Efficacy and Safety of PF-04965842 With or Without Topical Medications in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis (JADE EXTEND)

Dermatitis, Atopic

China, United States, Spain, Taiwan, Germany, Australia, Canada, Hungary, Korea, Republic of, Poland, Serbia, Bulgaria, Czechia, Japan, Latvia, United Kingdom, Belgium, Israel, Italy, Finland, Mexico, Romania, Slovakia, Argentina, Brazil, Chil... and more
Prof. Doron Gothelf MD

Completed

Clinical Trial: The Efficacy of Janssen's Icon Application (App) in Improving Adherence to Treatment With Stimulant Medications in Children With Attention Deficit/Hyperactivity Disorder (App ADHD)

Children Aged 6-18 Years With the Diagnosis of ADHD

Israel

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