Search clinical trials for: Bioavailability Pharmacokinetic Formulation

Total 16205 results

Shire

Terminated

A Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension Formulations of Maribavir to the Current Maribavir Tablet Formulation Administered in Healthy Adult Participants

Healthy Volunteers

United States
Naturex SA
Biofortis Mérieux NutriSciences

Completed

Pharmacokinetics Assessing Bioavailability of Gingerols and Shogaols of Five Ginger Extracts (KING)

Healthy Subject

France
Merck Sharp & Dohme LLC

Completed

Bioavailability of Doravirine (MK-1439) Experimental Nano Formulations in Healthy Adults (MK-1439-046)

Human Immunodeficiency Virus-1 (HIV-1)
Children's Mercy Hospital Kansas City
Midwest Cancer Alliance

Completed

Comparative Pharmacokinetics of a Compounded 6-mercaptopurine Liquid Formulation Preparation and Tablets

Acute Lymphoblastic Leukemia

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Assess the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics (PK) of TAK-931 in Participants With Advanced Solid Tumors

Neoplasms, Advanced Solid

Netherlands
Bayer

Completed

Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body

Solid Tumors Harboring NTRK Fusion

Germany
Novartis Pharmaceuticals

Completed

A Phase I, Exploratory, Intra-patient Dose Escalation Study to Investigate the Preliminary Safety, Pharmacokinetics, and Anti-tumor Activity of Pasireotide (SOM230) s.c.Followed by Pasireotide LAR in Patients With Metastaticmelanoma or Metastatic Merkel Cell Carcinoma

Metastatic Melanoma and Merkel Cell Carcinoma

Germany, Switzerland
Yung Shin Pharm. Ind. Co., Ltd.
Taichung Veterans General Hospital

Completed

Pharmacokinetics of Two Formulation of Tenofovir Disoproxil Fumarate

Pharmacokinetic of Tenofovir in Healthy Subjects

Taiwan
Agios Pharmaceuticals, Inc.

Completed

A Study to Assess the Relative Bioavailability and Effect of Food on the Coated Granule Formulation of Mitapivat in Healthy Participants

Healthy Volunteers

United States
Novartis Pharmaceuticals

Completed

Bioavailability Study Comparing Two New Nilotinib Tablet Formulations to an Established Nilotinib Capsule Formulation in Healthy Volunteers

Healthy
Radboud University Medical Center

Completed

Bioequivalence Study in Healthy Volunteers of a New Paediatric Formulation of Valacyclovir (VALID-I)

Varicella Zoster Virus Infection | Herpes Simplex Virus Infection

Netherlands
Pfizer

Completed

Study To Characterize Mass Balance, Absolute Bioavailability, Fraction Absorbed And Pharmacokinetics Of 14C PF-06882961

Healthy Volunteer

Netherlands
Otsuka Pharmaceutical Development & Commercialization...

Completed

A 6-Month Safety, Efficacy, and Pharmacokinetic (PK) Trial of Delamanid in Pediatric Participants With Multidrug Resistant Tuberculosis (MDR-TB)

Multidrug Resistant Tuberculosis

Philippines, South Africa
Boston Pharmaceuticals

Completed

Study to Determine the Single and Repeat Dose Pharmacokinetics, Food Effect, Proton Pump Inhibitor (PPI) Drug Interaction, Safety and Tolerability of Oral Prototype Formulations of BOS172767 in Healthy Subjects

Healthy Subjects

United Kingdom
Boston Pharmaceuticals

Completed

Study to Determine the Relative Bioavailability, Single and Repeat Dose Pharmacokinetics, Safety and Tolerability of BOS172767 Enantiomers in Healthy Subjects

Healthy Participants

United Kingdom
Radboud University Medical Center

Completed

Pharmacokinetic Study of Two Generic Co-formulations of Lopinavir/Ritonavir for HIV Infected Children (SURF) (SURF)

HIV Infections

Netherlands
University of Maryland, Baltimore
Food and Drug Administration (FDA)

Completed

Class 3 Biowaivers

Healthy

United States
University of Maryland, Baltimore
Food and Drug Administration (FDA)

Completed

Impact of Formulation on Ciprofloxacin Oral Absorption

Healthy

United States
AstraZeneca
Acerta Pharma BV

Completed

A Study to Evaluate Effects of Proton-pump Inhibitor on Acalabrutinib Capsule When Administered Orally With COCA-COLA in Healthy Participants

Infectious Disease

United States
Innocoll
Premier Research Group plc

Completed

Pharmacokinetics, Relative Bioavailability and Safety of Xaracoll Implant

Hernioplasty

United States
Radboud University Medical Center
Hoffmann-La Roche

Completed

The Pharmacokinetic Study of Saquinavir New Tablet Formulation in HIV-infected Pregnant Women.

HIV Infections

United Kingdom, Netherlands, Germany, Spain, Thailand
GlaxoSmithKline

Completed

To Assess Bioavailability, Food Effect and Pharmacokinetics of Gepotidacin Tablets: A Phase I, Single-Dose, 2 Part Study in Healthy Subjects.

Infections, Bacterial

United States
Pfizer

Completed

Measure Exposure Of Tanezumab In Healthy Volunteers When Administering The Drug Subcutaneously

Healthy Volunteers

United States
Genentech, Inc.

Completed

A Study to Determine the Bioavailability of Various Formulations of GDC-0134 in Healthy Female Participants of Non-Childbearing Potential

Healthy Volunteers

United States
argenx

Completed

A Study to Compare the PK, PD and Safety and Tolerability of a SC With an IV Formulation of ARGX-113 in Healthy Male Subjects

Bioavailability Study

Netherlands
ViiV Healthcare

Terminated

A Relative Bioavailability and Food-Effect Study of GSK3640254 Tablet and Capsule Formulations in Healthy Participants

HIV Infections

United States
Celgene

Completed

Relative Bioavailability Study of CC-292

Healthy Volunteers

United States
North Carolina Agriculture & Technical State University

Completed

Avenanthramide and Saponin Bioavailability in Oat Bran

Pharmacokinetics | Polyphenols | Human Health
GlaxoSmithKline

Completed

Relative Bioavailability Study of Marketed and Lower Dose Ambrisentan in Healthy Adult Participants

Hypertension, Pulmonary

United Kingdom
AstraZeneca
Acerta Pharma, LLC

Completed

A Study of Acalabrutinib Suspension to Evaluate Relative Bioavailability and Proton-pump Inhibitor Effect in Healthy Volunteers

Pharmacokinetics | Bioavailability

United States
NeuroActiva, Inc.

Unknown

Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831 (NEUROSIVIR)

Severe Acute Respiratory Syndrome | Covid19 | Corona Virus Infection | Severe Acute Respiratory Syndrome (SARS) Pneumonia | Neurodegeneration | Neuroinflammatory Response | Severe Acute Respiratory Infection | Severe Acute Respiratory Syndrome of Upper Respiratory Tract

United States
Clinical Nutrition Research Center, Illinois Institute...

Completed

Bioavailability and Pharmacokinetics of Mango (MG)

Healthy Subjects

United States
Clinical Nutrition Research Center, Illinois Institute...

Completed

Bioavailability and Pharmacokinetic Parameters of Watermelon (Rind, Flesh and Seeds) Polyphenols (WM)

Healthy Subjects

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Relative Bioavailability (rBA) of Evobrutinib Intended Commercial and Clinical Tablets, and Effect of Food on Intended Commercial Tablets

Healthy

Germany
Cerecin

Completed

Study to Compare the Pharmacokinetics of Tricaprilin Formulations and a Placebo on Ketone Body Production

Alzheimer Disease

Australia
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Effect of Meal Composition and Timing on Evobrutinib Bioavailability

Healthy

Germany
Central Institute of Mental Health, Mannheim

Terminated

Cannabidiol - an in Vivo Innovative Drug Delivery Study

Pharmacokinetics, Bioavailability

Germany
Amgen

Completed

A Study to Evaluate the Safety, Tolerability Pharmacokinetics, and Pharmacodynamics of a New Spray Dried Dispersion (SDD) Formulation of CC-11050 After Single Dose of CC-11050 and to Evaluate the Pharmacokinetics of CC-11050 Under Fasted and Fed Conditions and After Coadministration With Omeprazole

Healthy Volunteers

United States
NewLink Genetics Corporation

Completed

Oral Bioavailability,and Food Effect Study and Single Ascending Dose PK Study in Healthy Male Volunteers

Healthy

Canada
Hoffmann-La Roche

Completed

A 2 Part Study to Assess the Relative Bioavailability of Tablet Formulation Compared to Capsule Formulation and the Effect of Food and Taste Assessment on the Tablet Formulation in Healthy Participants

Healthy Volunteers

United States
NewLink Genetics Corporation

Completed

Single Ascending Dose PK, Oral Bioavailability and Food Effect Study in Healthy Male Volunteers (NLG2111)

Healthy

United States
Pfizer

Completed

PK and Bioavailability Comparison of Tofacitinib Between a Modified Release and The Immediate Release Formulation

Healthy

China
Janssen Research & Development, LLC

Completed

A Study to Assess the Relative Oral Bioavailability and Food Effect of Single-dose of JNJ-64417184 in Healthy Participants

Healthy

United States
Université de Sherbrooke

Completed

Pharmacokinetics of Omega-3 Monoglycerides

Healthy

Canada
Université de Sherbrooke

Unknown

Pharmacokinetic Study on Three Formulations of Curcumin With Different Carriers

Healthy

Canada
GlaxoSmithKline
Quotient Sciences

Completed

A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772

Autoimmune Diseases

United Kingdom
Bernard Fioretti

Completed

Pilot Study to Evaluate the Plasma Profile of Revifast

Nutrient; Excess | Product Use Issue

Italy
Drugs for Neglected Diseases
Bayer; Bill and Melinda Gates Foundation

Completed

First in Man Clinical Trial of Emodepside (BAY 44-4400)

Healthy Volunteers

United Kingdom
Children's Hospital of Philadelphia

Withdrawn

Gastrointestinal Implications of Voriconazole Exposure (GIVE)

Infection

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study to Compare Pharmacokinetic and Safety Profiles of Different Formulations of SHR-1314 After Subcutaneous Injection in Healthy Subjects

Pharmacokinetic

3

Subscribe