Search clinical trials for: Biologics

Total 712 results

Innovent Biologics (Suzhou) Co. Ltd.

Active, not recruiting

Efficacy and Safety of IBI310 Combined With Sintilimab in Patients With Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

China
Innovent Biologics (Suzhou) Co. Ltd.

Active, not recruiting

A Study to Evaluate the Similarity in Pharmacokinetics and Safety of IBI310 and Ipilimumab（YERVOY）in Adult Healthy Chinese Male Volunteers

Healthy Subjects

China
Innovent Biologics (Suzhou) Co. Ltd.

Terminated

IBI188 Combination Therapy in Solid Tumors

Osteosarcoma | Lung Adenocarcinoma | Solid Tumors

China
LimmaTech Biologics AG
GlaxoSmithKline

Completed

Safety and Immunogenicity of a Klebsiella Pneumoniae Tetravalent Bioconjugate Vaccine (Kleb4V)

Klebsiella Pneumoniae Infection

Germany
Kasr El Aini Hospital

Active, not recruiting

Biologic Therapy in Pediatric JIA Uveitis

Juvenile Idiopathic Arthritis Associated Uveitis

Egypt
Synermore Biologics Co., Ltd.
Synermore Biologics USA Limited

Completed

Comparison of SYN023 to Human Rabies Immune Globulin in Post Exposure Prophylaxis of Rabies (ARPEP)

Rabies

United States, Philippines
Medigen Vaccine Biologics Corp.

Completed

A Study to Evaluate Immunogenicity and Safety of MVC-COV1901 Compared With AZD1222 Against COVID-19 in Adults

Covid19 Vaccine

Paraguay
Medigen Vaccine Biologics Corp.

Completed

Long-Term Immunogenicity Study of Inactivated EV71 Vaccine in Children

Enterovirus 71 Human

Taiwan
Queen Mary University of London

Completed

Th17 Responses Evaluated in RA Patients on Inhibitors of TNFα (THERAPIST)

Rheumatoid Arthritis

United Kingdom
Apeiron Biologics
Apeiron Respiratory Therapies GmbH

Completed

Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Inhaled APN01 Developed as Treatment for COVID-19

Covid19

Austria
BlueWillow Biologics
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Active, not recruiting

A Safety and Immunogenicity of Intranasal Nanoemulsion Adjuvanted Recombinant Pandemic Flu Vaccine in Healthy Adults (IN-NE-rH5)

Influenza, Pandemic

United States
Innovent Biologics (Suzhou) Co. Ltd.

Active, not recruiting

IBI310 in Combination With Sintilimab in Patients With DNA Mismatch Repair Deficient (dMMR)/Microsatellite Instability High (MSI-H) Locally-advanced or Metastatic Colorectal Cancer

Colorectal Cancer

China
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Single Dose Tolerability and Pharmacokinetics of IBI112 in Healthy Subjects

Healthy Subjects

China
Innovent Biologics (Suzhou) Co. Ltd.

Active, not recruiting

A Study of IBI302 in Patients With nAMD

Neovascular Age-related Macular Degeneration

China
Medigen Vaccine Biologics Corp.

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of COVID-19 Vaccine, CT-COV-21 Extension Study

Covid19 Vaccine

Taiwan
McGuire Institute
Markman Biologics Corporation

Completed

Pilot Study for Healing and Safety Outcomes in Gingival Recession

Gingival Recession

United States
Medical Centre Leeuwarden

Completed

Craving to Biologics Used in Severe Asthma (CROCUS)

Asthma

Netherlands
Jiangsu Province Centers for Disease Control and...
CanSino Biologics Inc.

Completed

Study on Sequential Immunization of Inactivated COVID-19 Vaccine and Recombinant COVID-19 Vaccine (Ad5 Vector) in Elderly Adults

COVID-19

China
OPKO Health, Inc.

Terminated

A Phase 3, Multicenter Study To Evaluate The Efficacy And Safety Of MOD-4023 In Adults With Growth Hormone Deficiency

Adult Growth Hormone Deficiency

Israel
GenSight Biologics

Active, not recruiting

Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year (REFLECT)

Leber Hereditary Optic Neuropathy

Belgium, Spain, United States, France, United Kingdom, Taiwan, Italy
Andres J. M. Ferreri
AGC Biologics S.p.A.

Completed

RCHOP Chemoimmunotherapy Preceded BY BBB Permeabilization by t-NGR Necrosis Factor (INGRID)

Lymphoma, Large B-Cell, Diffuse

Italy
GenSight Biologics

Completed

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation (RESCUE)

Optic, Atrophy, Hereditary, Leber

United Kingdom, United States, France, Germany, Italy
Chang Gung Memorial Hospital
Medigen Vaccine Biologics Corp.

Active, not recruiting

The Immune Response of Heterologous Boost Third Dose of mRNA and Protein COVID-19 Vaccine

COVID-19 | Breakthrough Infection

Taiwan
AGC Biologics S.p.A.

Completed

A Modified Phase I Study of NGR-hTNF in Advanced Solid Tumors

Advanced Solid Tumors

Italy
The First Affiliated Hospital with Nanjing Medical...
Innovent Biologics (Suzhou) Co. Ltd.

Active, not recruiting

Sintilimab in Combination With Chemotherapy in Neoadjuvant Treatment of Potentially Resectable Esophageal Cancer

Esophageal Squamous Cell Carcinoma

China
Sichuan University
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Safety and Tolerability Evaluation of Sintilimab in Combination With Radiation in Stage IV NSCLC Patients

Stage IV NSCLC

China
Cedars-Sinai Medical Center
Synthetic Biologics Inc.

Terminated

Efficacy and Safety of SYN-010 in IBS-C

Irritable Bowel Syndrome With Constipation

United States
Hospital Mutua de Terrassa

Completed

Evaluation of the Safety and Effectiveness of Direct-acting Antiviral Drugs in the Treatment of Hepatitis C in Patients With Inflammatory Bowel Disease: National Multicenter Study (MIC project)

Inflammatory Bowel Diseases | Hepatitis C Virus Infection

Spain
Eli Lilly and Company
GlaxoSmithKline; Shanghai Junshi Bioscience Co., Ltd.; Vir Biotechnology, Inc.; AbCellera Biologics Inc...

Completed

A Study of Immune System Proteins in Participants With Mild to Moderate COVID-19 Illness (BLAZE-4)

COVID-19

United States, Puerto Rico, Argentina
Medigen Vaccine Biologics Corp.

Completed

A Study to Evaluate MVC-COV1901 Vaccine Against COVID-19 in Elderly Adults

Covid19 Vaccine

Taiwan
Medigen Vaccine Biologics Corp.

Completed

A Study o Evaluate the Safety, Tolerability, and Immunogenicity of MVC-COV1901, CT-COV-21 Sub-study

Covid19 Vaccine

Taiwan
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Study of Bevacizumab With Different Manufacturing Process in Healthy Male Subjects

Healthy Male Subjects

China
BlueWillow Biologics
Porton Biopharma Ltd.

Completed

A Safety and Immunogenicity of Intranasal Nanoemulsion Adjuvanted Recombinant Anthrax Vaccine in Healthy Adults (IN NE-rPA)

Anthrax

United States
University of Alabama at Birmingham

Terminated

Non-Surgical Treatment for Rotator-Cuff Tears Using Platelet-Rich-Plasma

Partial Tear of Rotator Cuff | Tendinopathy of Rotator Cuff

United States
Medtronic Spinal and Biologics

Completed

Diffusion MRI-1 Imaging Database (dMRI-1)

Epilepsy | Healthy | Tumor | Other

United States, Canada
Synthetic Biologics Inc.
Spaulding Clinical Research LLC

Completed

Multiple Ascending Dose Study to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered SYN 020

Enteritis Caused by Radiation

United States
Medigen Vaccine Biologics Corp.

Completed

A Study to Evaluate MVC-COV1901 Vaccine Against COVID-19 in Adolescents

Covid19 Vaccine

Taiwan
Medigen Vaccine Biologics Corp.

Completed

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of an EV71 Vaccine

Enterovirus 71 Infection

Taiwan, Vietnam
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Safety and Efficacy of IBI306 in Chinese Subjects With Non-familial Hypercholesterolemia

Hypercholesterolemia

China
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Phase 1 Study Evaluating the Safety, Tolerability, and Initial Efficacy of IBI188 in Advanced Malignancies

Advanced Malignancies

China
Queen Mary University of London
Barts & The London NHS Trust; Pharma Nord; Fischer Family Trust; The AIM Foundation and other collaborators

Completed

Trial of Vitamin D to Reduce Risk and Severity of COVID-19 and Other Acute Respiratory Infections (CORONAVIT)

Covid19 | Acute Respiratory Tract Infection

United Kingdom
Jiangsu Province Centers for Disease Control and...
CanSino Biologics Inc.

Completed

Study on Sequential Immunization of Inactivated SARS-CoV-2 Vaccine and Recombinant SARS-CoV-2 Vaccine (Ad5 Vector)

COVID-19

China
Mylan Inc.
Mylan GmbH

Completed

MYL-1401A Efficacy and Safety Comparability Study to Humira®

Psoriasis | Arthritis, Psoriatic

Bulgaria, Estonia, Hungary, Poland, Russian Federation, Ukraine
Heat Biologics

Withdrawn

A Phase 1 Study of PTX-35 in Healthy Volunteers

Healthy Volunteer
Eli Lilly and Company
National Institute of Allergy and Infectious Diseases (NIAID); Shanghai Junshi... and other collaborators

Completed

A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and Staff (BLAZE-2)

COVID-19 | SARS-CoV2

United States
Medigen Vaccine Biologics Corp.

Completed

A Study to Evaluate MVC-COV1901 Vaccine Against COVID-19 in Adult (COVID-19)

Covid19 Vaccine

Taiwan, Vietnam
Medigen Vaccine Biologics Corp.

Completed

A Study to Evaluate the Safety and Immunogenicity of MVC-COV1901 Against COVID-19

COVID-19

Taiwan
Chinese University of Hong Kong
University of Malaya

Terminated

Risk of Hepatitis Flare in Patients With Previous Hepatitis B Virus Exposure Amongst Patients

Immunosuppression | Occult Hepatitis B | Biological Substance; Adverse Effect

Hong Kong
AGC Biologics S.p.A.
Horizon 2020 - European Commission

Terminated

Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma

Acute Myeloid Leukemia | Multiple Myeloma

Italy, Czechia
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study Evaluating the Safety, Tolerability, and Initial Efficacy of Recombinant Human Anti-cluster Differentiation Antigen 47 (CD47) Monoclonal Antibody Injection (IBI188) in Patients With Advanced Malignant Tumors and Lymphomas

Advanced Malignancies

United States

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