Search clinical trials for: CYP2C19 polymorphisms

Total 1574 results

Radboud University Medical Center

Recruiting

Pragmatic Optimized Rifampicin Trial (PORT)

Tuberculosis, Pulmonary

Netherlands
FEMPHARMA Kft.

Recruiting

Zinc-containing Vaginal Gel and Oral Fluconazole for Vulvovaginal Candidiasis.

Vulvovaginal Candidiasis | Vaginal Yeast Infections

Hungary
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

2R2: Higher Dose Rifampin for 2 Months vs Standard Dose Rifampin for Latent TB. (2R2)

Latent Tuberculosis

Canada, Indonesia, Vietnam
Makerere University

Completed

Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy (SAEFRIF)

Tuberculosis

Uganda
Eisai Co., Ltd.

Completed

A Study to Assess the Effect of Food Intake and Drug-drug Interactions of E7090 When Co-administered With Rabeprazole or Rifampin in Healthy Participants

Healthy Participants

Japan
University of Colorado, Denver
Cystic Fibrosis Foundation; Colorado Clinical & Translational Sciences Institute

Completed

Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis

Cystic Fibrosis

United States
Kirby Institute

Completed

Safety and Efficacy of Reduced Versus Standard Dose Efavirenz (EFV) Plus Two Nucleotides in Antiretroviral-naïve Adults. (ENCORE1)

HIV Infections

Australia
Tuberculosis Research Centre, India

Completed

Comparing Daily vs Intermittent Regimen of ATT in HIV With Pulmonary Tuberculosis

HIV Infection | Pulmonary TB

India
Shanghai Public Health Clinical Center
Zhejiang University; Yunnan Provincial Infectious Disease Hospital; Shenzhen... and other collaborators

Unknown

Rifampicin vs Rifabutin in HIV/AIDS Patients Combined With Tuberculosis (RRHT)

Tuberculosis, Pulmonary | AIDS

China
Harvard University Faculty of Medicine
National Institute of Allergy and Infectious Diseases (NIAID); Sanofi; University... and other collaborators

Completed

Trial of High-Dose Rifampin in Patients With TB (HIRIF)

Tuberculosis

United States, Peru, United Kingdom
Shanghai Public Health Clinical Center

Completed

ART Drug Dosage Adjustment in HIV-infected Population

HIV Infections

China
AstraZeneca

Completed

Study to Assess the Effect of Rifampicin (CYP Inducer) on Blood Levels and Safety of Olaparib in Patients With Advanced Solid Tumours

Solid Tumours

Netherlands, Belgium
University of California, San Francisco
Makerere University; Infectious Diseases Research Collaboration, Uganda; Makerere...

Completed

Early HIV Therapy in Patients With High CD4 Cell Counts (EARLI)

HIV

Uganda
PENTA Foundation
Medical Research Council; ANRS, Emerging Infectious Diseases

Unknown

BREATHER (PENTA 16) Short-Cycle Therapy (SCT) (5 Days on/2 Days Off) in Young People With Chronic HIV-infection (BREATHER)

HIV

United Kingdom, Uganda, Ireland, United States, France, Germany, Thailand, Ukraine
Tibotec Pharmaceuticals, Ireland

Completed

A Study of TMC278 in Human Immunodeficiency Virus Type 1 Infected Patients, Who Are Not Treated With Antiretroviral Medicines

Human Immunodeficiency Virus Type 1

United States, France, United Kingdom, China, Germany, South Africa, Russian Federation, Argentina, Brazil, Puerto Rico, Austria, Thailand, Mexico, Uganda
Boehringer Ingelheim

Completed

Drug Interaction Study With Rifampicin and Afatinib

Healthy

Germany
Pfizer

Completed

A Study To Investigate The Drug-Drug Interaction Potential Of Rifampin OnThe Investigational Agent Palbociclib (PD-0332991)

Healthy

United States
Radboud University Medical Center
Sanofi; European and Developing Countries Clinical Trials Partnership (EDCTP); National Institute for Public Health and the Environment (RIVM) and other collaborators

Completed

Pharmacokinetics and Pharmacodynamics of High Versus Standard Dose Rifampicin in Patients With Pulmonary Tuberculosis (High RIF)

Tuberculosis

Tanzania
Center for Clinical Pharmacology Research Bdbeq...
University of the Republic, Uruguay

Completed

Efavirenz Comparative Bioavailability (efv600)

Healthy

Uruguay
Pfizer

Completed

Anidulafungin Candidemia/Invasive Candidiasis Intensive Care Study (ICE)

Invasive Candidiasis

Czech Republic, Belgium, Austria, Portugal, Russian Federation, Turkey, Canada, Germany, Italy, United Kingdom, Hungary, France, Slovakia, Denmark, Romania, Netherlands, Poland, Greece, Ukraine
Bristol-Myers Squibb

Completed

Effectiveness and Safety of Two Forms of Stavudine in HIV-Infected Patients

HIV Infections

United States, Canada, Belgium, Mexico, Italy, France, Argentina, Israel, Spain, Brazil, Puerto Rico, Australia, Portugal, Russian Federation, South Africa, Thailand
McMaster University
The Physicians' Services Incorporated Foundation

Unknown

A Pilot Study of Inflammatory Markers in Alzheimer's Disease

Alzheimer's Disease

Canada
French National Agency for Research on AIDS and...

Completed

Feasibility Study of a Once Daily Antiretroviral Regimen in Vietnam (ANRS 1210 VIETAR)

HIV Infection

Vietnam
Dupont Merck

Completed

A Study of Efavirenz in Combination With Stavudine and Didanosine

HIV Infections

United States
Daniel Benjamin
Pediatric Pharmacology Research Units Network

Completed

Pharmacokinetics (PK) Study of a Fluconazole Loading Dose in Infants and Toddlers

Candidiasis

United States
Kevin Winthrop
Patient-Centered Outcomes Research Institute; Medical University of South Carolina and other collaborators

Recruiting

Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease (MAC2v3)

Mycobacterium Avium Complex | Nontuberculous Mycobacterium Infection

United States, Canada
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of the Effects of Omeprazole and Rifampin on the Pharmacokinetics of VX-548 in Healthy Participants

Pain

Australia
Bellus Health Inc. - a GSK company

Completed

Evaluation of the Effect of Rifampin and Rabeprazole on the Pharmacokinetics of Camlipixant

Healthy

Canada
Kilimanjaro Clinical Research Institute
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Evaluation of Pharmacokinetics and Safety Tolerability of Higher Doses of Rifampic (HighRif C)

Clinical Trial

Tanzania
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Elvucitabine/Efavirenz/Tenofovir Versus Lamivudine/Efavirenz/Tenofovir in Human Immunodeficiency Virus (HIV)-1 Infected, Treatment-naive Participants

HIV Infections

United States, Puerto Rico
Insmed Incorporated

Completed

A Study to Assess Pharmacokinetics (PK) of Brensocatib Alone and With Multiple Doses of Rifampin or Esomeprozole in Healthy Participants

Healthy Volunteers

United States
Scynexis, Inc.

Completed

Phase 3 Study of Oral Ibrexafungerp (SCY-078) Vs. Placebo in Subjects With Recurrent Vulvovaginal Candidiasis (VVC) (CANDLE)

Recurrent Vulvovaginal Candidiasis

United States
Peking Union Medical College Hospital
Gilead Sciences

Active, not recruiting

Biktarvy in Treatment-Naïve Late Presenters With HIV-1 Infection

HIV-1-infection

China
National Institute of Allergy and Infectious Diseases...
Pfizer

Completed

Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)

HIV Infections | Mycoses | Candidiasis

United States, Tanzania
University of California, San Francisco

Completed

Drug-Drug Interaction Between Rifampin and Fluvastatin

Drug-drug Interaction

United States
Peking University Shenzhen Hospital
Shanghai Shyndec Pharmaceutical Co., Ltd.

Completed

Terconazole Vaginal Suppository vs Fluconazole for the Treatment of Severe Vulvovaginal Candidiasis

Vulvovaginal Candidiasis

China
Shanghai Public Health Clinical Center
Yunnan Provincial Infectious Disease Hospital; The Second Hospital of Nanjing...

Completed

Optimization of Antiretroviral Therapy (OAT)

HIV Infections

China
Hospices Civils de Lyon

Completed

Staphylococcal Acute Post-Operative PJI Treated With 'DAIR' And Impact Of Rifampin (IPASTAPH)

Bone and Joint Infection | Antibiotic Resistant Staphylococcus Aureus Infection

France
McMaster University
The Physicians' Services Incorporated Foundation

Completed

Efficacy of Metronidazole Versus Metronidazole and Rifampin in CDAD Treatment

Antibiotic-Associated Diarrhea | Clostridium Enterocolitis | Pseudomembranous Colitis | Pseudomembranous Enterocolitis | Pseudomembranous Enteritis

Canada
ViiV Healthcare
GlaxoSmithKline

Terminated

Dose-finding Study of GSK2248761 in Antiretroviral Therapy-Naive Subjects (SIGNET) (SIGNET)

Infection, Human Immunodeficiency Virus

Spain, France, Germany
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Fluconazole and Itraconazole on Erdafitinib Pharmacokinetics in Healthy Adult Participants

Healthy

Belgium
The University of Texas Health Science Center at...
Pfizer

Completed

Use of Azithromycin and Rifabutin Administered 3 Times Weekly for the Treatment of M. Avium Complex (MAC) Lung Disease

Mycobacterium Avium Complex

United States
Centre for the AIDS Programme of Research in South...

Completed

Trial to Assess the Impact of PrEP to Tenofovir Gel on the Efficacy of Tenofovir-containing ART on Viral Suppression (TOAST)

Antiretroviral Treatment Outcomes

South Africa
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy Study of Posaconazole vs. Fluconazole for Prevention of Invasive Fungal Infection (P05387 AM1)(COMPLETED)

Leukopenia
University of Minnesota

Completed

Sustiva Levels With Use of a Gel Capsule

HIV Infections | HIV

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Rifampicin on the Pharmacokinetics of Apatinib

Neoplasms

China
Pfizer

Withdrawn

Effect Of Rifampin On Pharmacokinetics Of Sitaxsentan

Pulmonary Arterial Hypertension
Universidad Nacional de Colombia

Completed

Safety and Clinical and Microbiological Efficacy of the Combination of Fluconazole and Secnidazole for the Treatment of Symptomatic Vaginal Discharge

Vaginal Discharge

Colombia
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Gilead Sciences

Completed

Efficacy and Safety of 2 Raltegravir Doses in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis

HIV Infections | Tuberculosis

France, Brazil
All India Institute of Medical Sciences, New Delhi
Ministry of Health & Family Welfare, India

Completed

Efficacy of Thrice Weekly Directly Observed Treatment, Short-course (DOTS) in HIV-associated Tuberculosis

HIV Infections | Acquired Immunodeficiency Syndrome | Tuberculosis

India

Search clinical trials for: CYP2C19 polymorphisms

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Moldova

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations