Search clinical trials for: Dose Response

Total 33110 results

National Cancer Institute (NCI)

Completed

Safety and Tolerability of a Modified Vaccinia Ankara (MVA)-Based Vaccine Modified to Express Brachyury and T-cell Costimulatory Molecules (MVA-Brachyury-TRICOM)

Breast Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Tumors (Others)

United States
National Cancer Institute (NCI)

Terminated

Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma

Renal Cell Carcinoma | Renal Cell Cancer | Hereditary Leiomyomatosis

United States
Maria Sklodowska-Curie National Research Institute...

Unknown

Hypofractionated Radiotherapy With Sequential Chemotherapy in Marginally Resectable Soft Tissue Sarcomas of Extremities or Trunk Wall (UN-RESARC)

Sarcoma | Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Myxoid Liposarcoma | Myosarcoma | Histiocytic Sarcoma | Pleomorphic Liposarcoma | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Myxofibrosarcoma | Dedifferentiated Liposarcoma | Malignant Peripheral Nerve Sheath Tumors | Malignant Triton Tumor | Pleomorphic... and other conditions

Poland
Novo Nordisk A/S

Completed

Dose-response, Safety and Efficacy of Oral Semaglutide Versus Placebo and Versus Liraglutide, All as Monotherapy in Japanese Subjects With Type 2 Diabetes (PIONEER 9)

Diabetes Mellitus, Type 2 | Diabetes

Japan
Assiut University

Unknown

Immunologic Responses to Single and Double Doses of COVID-19 Vaccines in Egyptians

COVID-19 Vaccines
Institut Bergonié
Novartis

Terminated

Phase III Trial Evaluating the Effectiveness of a Dose Adjustment of Imatinib Mesylate on the Molecular Response (MIM)

Leukemia, Myeloid, Chronic-Phase

France
Novartis Pharmaceuticals

Completed

Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors

Metastatic Colorectal Cancer | Gastric Cancer | Advanced Solid Tumors | Metastatic Breast Cancer | Gastroesophageal Junction Cancer | Recurrent Glioblastoma Multiforme | Advanced Pancreatic Adenocarcinoma | Safety | Triple Negative Metastatic Breast Cancer | Dose Escalation | Preliminary Efficacy | Hormone Receptor...

Canada, United Kingdom, Spain, Germany, Italy, Belgium, Australia, United States
Ferring Pharmaceuticals

Completed

A Dose-response Trial Using FE 999049 in Japanese Women Undergoing in Vitro Fertilisation (IVF) / Intracytoplasmic Sperm Injection (ICSI) Treatment

Infertility

Japan
PhaseBio Pharmaceuticals Inc.

Terminated

Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS). (VANGARD)

Pneumonia | Respiratory Failure | Respiratory Insufficiency | COVID 19 | Acute Respiratory Distress Syndrome | SARS-CoV-2 | Coronavirus | Cytokine Storm | Pulmonary Edema | Cardiac Event | Respiratory Complication | Cardiac Dysfunction | Hypoxemic Respiratory Failure | Hypoxic Respiratory Failure | Cardiac Failure | Cardiac... and other conditions

United States
GlaxoSmithKline

Completed

A Follow-up Extension Study to Evaluate the Persistence of Immune Response to GSK Biologicals' HPV Vaccine in Healthy Chinese Female Subjects Who Received Three Doses of the Vaccine in the HPV-058 Study

Cervical Intraepithelial Neoplasia

China
Cairo University

Completed

Plasma Endostatin Predicts Outcome of Septic AKI

Acute Kidney Injury Due to Sepsis

Egypt
Cancer Trials Ireland

Completed

Biomarkers of Response to Taxotere in HRPC. ICORG 08-08, V2

Prostate Cancer | Metastatic Cancer

Ireland
Ferring Pharmaceuticals

Completed

A Dose-response Trial Using rFSH FE 999049 in Women Undergoing IVF/ICSI Treatment

Infertility

Belgium, Denmark, Spain, Czechia
Udayana University

Completed

Comparison of CRP Levels, Neutrophil Count, and Clinical Outcomes of Low Dose Ketamine Between at Anesthesia Induction and at the End of Surgery in Patients Undergo Elective Laparotomy (PRO-Ketamine)

Inflammation | General Anesthesia | Laparotomy

Indonesia
University of Illinois at Urbana-Champaign

Completed

Nutritional Strategies to Augment the Postprandial Muscle Protein Synthetic Response to the Ingestion of a Low Dose of Protein in Middle-aged Women

Aging

United States
Sun Yat-sen University

Completed

Dietary Anthocyanins Improve Lipid Metabolism in a Dose - Dependent Manner

Dyslipidemias

China
National Institute of Allergy and Infectious Diseases...

Completed

Dose, Safety, Tolerability and Immunogenicity of a Stabilized Prefusion RSV F Subunit Protein Vaccine, VRC-RSVRGP084-00-VP (DS-Cav1), Alone or With Alum Adjuvant, in Healthy Adults

Respiratory Syncytial Virus

United States
PATH
International Centre for Diarrhoeal Disease Research, Bangladesh

Completed

Long-term Immunogenicity After Receipt of JE Vaccine and Antibody Response and Safety to a Booster Dose

Encephalitis, Japanese
Ilkos Therapeutic Inc.

Completed

Dose-response Relationship Study of S42909 on Leg Ulcer Healing

Venous Leg Ulcer

Spain, Hungary, Canada, United States, Brazil, Argentina, Austria, Czechia, Italy, Poland, Slovakia
Central Hospital, Nancy, France

Completed

Diagnostic Performance of Plasma Procalcitonin for the Detection of Blood Cultures Contaminations

Bacteremia | Contamination | Blood Culture Contamination

France
Lung Biotechnology PBC

Completed

Dose-response Study of the Safety and Efficacy of Beraprost Sodium Modified Release (BPS-MR) in Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United States, Belgium, Czechia, Germany, Ireland, Romania
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Terminated

Gene Expression Levels in Predicting Treatment Response in Patients With Stage IV Non-small Cell Lung Cancer

Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
Turku University Hospital
University of Helsinki

Completed

Dose Response Study of Dexmedetomidine in Orthopaedic Spine Surgery Patients (DoserespDex)

Pain, Postoperative

Finland
ARCIM Institute Academic Research in Complementary...
University Hospital Tuebingen

Completed

Dose-response Relationship of Mustard Flour Footbaths in Healthy Volunteers

Thermogenesis by Different-dosage Mustard Flour Footbaths

Germany
University of Valencia

Terminated

Dose-response of Talus Mobilizations (ANKLE_ROM)

Aging Problems

Spain
Meissa Vaccines, Inc.

Completed

Safety and Immune Response to an Investigational Vaccine Against Respiratory Syncytial Virus in Healthy Adults

Respiratory Syncytial Virus Infections

United States
King Faisal University
Mansoura University

Completed

Preoperative Ephedrine Attenuates the Hemodynamic Responses of Propofol During Valve Surgery: A Dose Dependent Study

Valve Surgery | Hypotension

Egypt, Saudi Arabia
Allerderm

Completed

Clinical Evaluation of Metal Panel Allergens: Dose Response Study

Dermatitis, Eczematous

Japan, United States, Germany, Italy, Netherlands, Switzerland
Allerderm

Completed

Clinical Evaluation of Metal Panel Allergens: Mercury, Aluminum and Palladium Dose Response Study

Contact Dermatitis

Sweden
Thomas Hatschek

Active, not recruiting

Neoadjuvant Response-guided Treatment of HER2 Positive Breast Cancer (PREDIX HER2)

Early-Stage Breast Carcinoma | HER-2 Positive Breast Cancer

Sweden
Central Adelaide Local Health Network Incorporated
Vaxine Pty Ltd

Unknown

Study of Sting Challenge and Serological Responses to Jack Jumper Venom Immunotherapy With Inulin as Adjuvant (Jumpvax) (Jumpvax)

Immunotherapy | Ant Sting

Australia
University of Vermont
International Centre for Diarrhoeal Disease Research, Bangladesh; Thrasher... and other collaborators

Completed

The Effects of Increased Inoculum on Oral Rotavirus Vaccine Take and Immunogenicity

Rotavirus Infection | Vaccine Response Impaired | Vaccine Virus Shedding

Bangladesh
Aga Khan University

Completed

Single Dose Tramadol Effect on Extubation Response and Quality of Emergence Post-supratentorial Intracranial Surgery

Brain Neoplasm

Pakistan
GlaxoSmithKline

Completed

Phase 2a, AMP Challenge, Dose Escalation Study to Assess the Dose Response for Topical Efficacy and Systemic Activity in Asthmatic Subjects

Asthma

United Kingdom, Germany
Jonsson Comprehensive Cancer Center

Withdrawn

Targeted Biopsies in Determining Response in Patients With Prostate Cancer Undergoing High-Dose-Rate Brachytherapy

Stage III Prostate Adenocarcinoma

United States
Ain Shams University

Completed

High Dose of Vitamin C on Mechanically Ventilated Septic Patients in Intensive Care Unit

Sepsis | Ventilator Associated Pneumonia ( VAP)

Egypt
Universidade Federal do Rio de Janeiro
Rio de Janeiro State Research Supporting Foundation (FAPERJ); Instituto de... and other collaborators

Withdrawn

Effects and Safety of Infusion of Low-Doses of Methylprednisolone in Early ALI and ARDS in Children (PEDALI)

Acute Respiratory Distress Syndrome | Acute Lung Injury

Brazil
Instituto de Seguridad y Servicios Sociales de...
SECRETARIA DE SALUD DEL ESTADO DE SONORA; CENTRO ESTATAL DE LA TRANSFUSION... and other collaborators

Unknown

CONVALESCENT PLASMA FOR ILL PATIENTS BY COVID-19 (COPLASCOV19)

COVID-19 | SARS-CoV 2 | Convalescence | Plasma | Doses

Mexico
The Immunobiological Technology Institute (Bio-Manguinhos)...
Wellcome Trust

Unknown

Duration of Immunity 10 Years After a Dose-response Study With Yellow Fever Vaccine - Complementary Study

Yellow Fever Vaccine

Brazil
Universidad Autonoma de Nuevo Leon

Completed

Therapeutic Effect of Botulinum Toxin A for the Treatment of Plantar Fasciitis.

Plantar Fascitis | Botulinum Toxins, Type A

Mexico
Universitaire Ziekenhuizen KU Leuven

Completed

Influence of H1-antihistamines on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.

Pruritus

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick

Pruritus

Belgium
Weill Medical College of Cornell University

Completed

Dose-Response Relationships for Hemidiaphragmatic Paresis Following Ultrasound-Guided Supraclavicular Block

Surgery of Right Upper Extremity

United States
Ziauddin University

Completed

Exercise Response on Dose Curve Among Class I Obese Young Adult Population

Obesity

Pakistan
Galeno Desenvolvimento de Pesquisas Clínicas
SocraTec R&D GmbH

Completed

Estriol and Trimegestone Dose-response Trial With Single Dose Application of Vaginal Rings

Pregnancy

Brazil
Allerderm

Completed

Clinical Evaluation of T.R.U.E. TEST® : Safety and Efficacy

Contact Dermatitis

United States, Denmark
ARCIM Institute Academic Research in Complementary...
University Hospital Tuebingen

Completed

Dose-Response Relationship of Ginger Flour Footbaths in Healthy Volunteers

Thermogenesis by Different-dosage Ginger Flour Footbaths

Germany
Riphah International University

Completed

Dose Response of Plyometric Training on Agility in Cricket Players

Athletic Injuries

Pakistan
Assiut University

Completed

Attenuation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation With Single Dose of Dexmedetomidine in Hypertensive Patients.

Stress Response During Laryngoscopy Intubation

Egypt
ContraFect

Completed

A Placebo-Controlled, Dose-Escalating Study to Examine the Safety and Tolerability of Single Intravenous Doses of CF-301 in Healthy Subjects

Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)

United States

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