Search clinical trials for: Drug-resistant tuberculosis

Total 1587 results

Foundation for Innovative New Diagnostics, Switzerland
Ludwig-Maximilians - University of Munich; Ifakara Health Institute; Centro de... and other collaborators

Active, not recruiting

TB-CAPT CORE Truenat Trial

Tuberculosis | Diagnoses Disease

Tanzania, Mozambique
Kaiser Permanente

Active, not recruiting

Brief Educational Video for Patients Prescribed LTBI Treatment

Latent Tuberculosis

United States
Johns Hopkins University
Cystic Fibrosis Foundation

Completed

Bacille Calmette-Guerin (BCG) Vaccine for Immune Protection Against Infections

Cystic Fibrosis | Bronchiectasis Adult | Non-Tuberculous Mycobacteria

United States
Vertex Pharmaceuticals Incorporated

Completed

Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

Cystic Fibrosis

United States, Spain, Ireland, Belgium, Netherlands, United Kingdom, Australia, France, Denmark, Germany, Italy, Canada
Medecins Sans Frontieres, Spain

Completed

Evaluation of Point-of-care Ultrasound in Children From 6 Months to 15 Years With Presumptive Tuberculosis

Tuberculosis

Guinea-Bissau, South Sudan
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); Makerere University and other collaborators

Completed

Simplified Isoniazid Preventive Therapy Strategy to Reduce TB Burden (SEARCH-IPT)

HIV/AIDS | Tuberculosis

Uganda
Shanghai Jiatan Pharmatech Co., Ltd

Enrolling by invitation

Sudapyridine (WX-081) in RR/MDR/XDR-tuberculosis Patients (WISH)

Rifampicin-resistant Tuberculosis

China
Fred Hutchinson Cancer Center
Merck Sharp & Dohme LLC

Completed

Phase I Open Label BCG Clinical Trial Assessing TB Drugs and Vaccines

Tuberculosis

United States
University Hospital, Linkoeping
Linkoeping University

Suspended

Drug Exposure and Safety of a Shorter Tuberculosis Treatment Based on High-Dose Rifampicin and Pyrazinamide (HIGHSHORT-RP)

Tuberculosis, Pulmonary

Sweden
Tuberculosis Research Centre, India
King George's Medical University, Lucknow; Mahavir Hospital and Research Centre... and other collaborators

Active, not recruiting

Four Months Moxifloxacin Containing Daily Regimen Study Among New Pulmonary Tuberculosis Patients

Tuberculosis, Pulmonary

India
Tuberculosis Research Centre, India
International Union Against Tuberculosis and Lung Diseases; Sarvodaya Charitable... and other collaborators

Active, not recruiting

Modified BPaL Regimen for Managing Pre-XDR TB and MDR (TI/NR) TB in India (mBPaL)

Pre-Extensively Drug-Resistant Pulmonary TB | Treatment Intolerant Multidrug-Resistant Pulmonary TB | Non-responsive Multidrug-Resistant Pulmonary TB

India
Johns Hopkins University

Completed

Clinical Practice Guidelines Versus Decision-support for Latent Tuberculosis Infection (LTBI) Management

Latent Tuberculosis

United States
United Therapeutics

Completed

FREEDOM - M: Oral Treprostinil as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, China, Israel, Belgium, Canada, France, India, Mexico, Austria, Italy, Netherlands, Poland, Puerto Rico
University of Oxford
Wellcome Trust; National Institute for Health Research, United Kingdom; University...

Active, not recruiting

Investigating Immune Responses to Aerosol BCG Challenge in Healthy UK Adults

Tuberculosis

United Kingdom
National Institute of Allergy and Infectious Diseases...

Terminated

Pretomanid in Adults With Hepatic Impairment

Tuberculosis

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)

Sickle Cell Disease

United States
National Taiwan University Hospital

Completed

Risk of SDRs Under 3HP and 1HP Regimen for LTBI

Latent Tuberculosis Infection

Taiwan
Vertex Pharmaceuticals Incorporated

Active, not recruiting

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

Cystic Fibrosis

United States, Spain, United Kingdom, Belgium, Netherlands, Denmark, Israel, New Zealand, France, Australia, Ireland, Germany, Sweden, Canada, Czechia, Switzerland, Portugal, Italy, Austria, Hungary, Norway, Poland, Greece
UCB Biopharma S.P.R.L.

Completed

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy (ARISE)

Focal-Onset Seizures | Drug-resistant Epilepsy

United States, Australia, Belgium, Bulgaria, Canada, Czechia, France, Germany, Hungary, Italy, Japan, Lithuania, Mexico, Poland, Portugal, Slovakia, Spain, Turkey, United Kingdom
Tuberculosis Research Centre, India
All India Institute of Medical Sciences, Bhubaneswar; Institute of Child Health... and other collaborators

Suspended

BCG Revaccination in Children and Adolescents (BRiC)

Tuberculosis | Tuberculosis Infection

India
Huashan Hospital

Active, not recruiting

Subclinical TB With Innovative Modified Short-course Regimens (SWIFT)

Tuberculosis

China
Sema Aytaç, PhD

Completed

Effect of Breathing Exercise on Fatigue in Patients With Pulmonary Tuberculosis

Fatigue | Tuberculosis, Pulmonary

Turkey
Research Center Borstel
Ludwig-Maximilians - University of Munich

Terminated

PredictEndTB Signature for Individualizing Treatment in Multidrug-Resistant Tuberculosis

Bacterial Infections | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Mycobacterial Infection

Germany, Moldova, Republic of, Romania, Ukraine
Obafemi Awolowo University Teaching Hospital
University Hospital Birmingham NHS Foundation Trust; Cures Within Reach

Completed

Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis) (ATORTUB)

Tuberculosis | Tuberculosis, Pulmonary

United Kingdom, Nigeria
University of Oklahoma

Completed

Screening Strategy for Early Diagnosis of Silicosis in At-Risk Populations in Oklahoma

Silicosis | Pneumoconiosis; Silica

United States
Allama Iqbal Open University Islamabad

Completed

Prokinetic Effect of Selected Nutraceuticals

Pulmonary Tuberculosis | Gastro-Intestinal Disorder

Pakistan
Imperial College Healthcare NHS Trust
Barts & The London NHS Trust; Royal Free Hospital NHS Foundation Trust; University... and other collaborators

Active, not recruiting

TB PCR in BAL and EBUS-TBNA (TRiBE)

Tuberculosis

United Kingdom
Pharmtechnology LLC
Altasciences Company Inc.

Completed

Single Dose Crossover Comparative Bioavailability Study of Two Formulations of Fluconazole 200 mg in Healthy Adult Subjects Under Fasting Conditions

Bioequivalence

Canada
University of California, San Francisco
Johns Hopkins University; National Heart, Lung, and Blood Institute (NHLBI); Makerere... and other collaborators

Active, not recruiting

TB Screening Improves Preventive Therapy Uptake (TB SCRIPT)

HIV | Latent Tuberculosis | Tuberculosis | Tuberculosis Prevention

Uganda
Tuberculosis Research Centre, India
National Institute of Epidemiology

Completed

Characterization and Durability of COVID-19 Vaccine Induced Immune Responses in Healthcare/Frontline Workers

Covid19

India
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Suspended

A Phase Ⅱ Clinical Trial of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02)

Tuberculosis

China
Michael Hoelscher
European and Developing Countries Clinical Trials Partnership (EDCTP)

Active, not recruiting

Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries (ERASE-TB)

Tuberculosis

Tanzania, Mozambique, Zimbabwe
Foundation for Innovative New Diagnostics, Switzerland
Ludwig-Maximilians - University of Munich; Heidelberg University; Swiss Tropical... and other collaborators

Active, not recruiting

TB-CAPT MTB/XDR Study

Tuberculosis | Diagnoses Disease | Resistance Bacterial

South Africa
BioVersys AG
TASK Applied Science

Completed

Pharmacokinetics of Ethionamide and Ethionamide Sulfoxide in Patients Established on Treatment for Tuberculosis.

Tuberculosis, Pulmonary

South Africa
University of California, San Francisco
University of Colorado, Denver; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Active, not recruiting

Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial)

HIV/AIDS | Latent Tuberculosis | Tuberculosis

Uganda
University of Oxford
University of Birmingham

Completed

Aerosol BCG Challenge Trial in Healthy UK Adults

Tuberculosis

United Kingdom
Otsuka Pharmaceutical Development & Commercialization...
Bill and Melinda Gates Foundation

Completed

A Phase 1/2 Trial of Multiple Oral Doses of OPC-167832 for Uncomplicated Pulmonary Tuberculosis

Pulmonary TB

South Africa
Helen Reynolds
Desmond Tutu HIV Centre; Infectious Disease Institute, Kampala, Uganda

Active, not recruiting

Drug Interactions Between Dolutegravir and Escalating Doses of Rifampicin (DoRIS)

Tuberculosis | Hiv

Uganda, South Africa
FibroGen

Terminated

Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States, France, United Kingdom, Korea, Republic of, Lebanon, Denmark, China, Italy, Spain, Serbia, Germany, Netherlands, Czechia, Brazil, Poland, Argentina, Colombia, Dominican Republic, Georgia, Hungary, Ireland, Mexico, Peru, Switzerlan... and more
Yale University
National Institute on Drug Abuse (NIDA); Ukrainian Institute on Public Health... and other collaborators

Active, not recruiting

Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the Community (MATLINK)

Depression | HIV Infections | Hepatitis B | Hepatitis C | Tuberculosis | Opioid-use Disorder | Syphilis

Kyrgyzstan, Moldova, Republic of, Ukraine
Boston Medical Center
Boston University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Completed

The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes

Tuberculosis | Alcohol Consumption | Treatment Adverse Effect

South Africa
University Hospital, Basel, Switzerland
Fachhochschule Nordwestschweiz

Withdrawn

miRNA in Sweat, a Novel Digital Biomarker for Detection of Active Tuberculosis (TB)

Active Tuberculosis

Switzerland
Creative Biosciences (Guangzhou) Co., Ltd.
Guangzhou Xiangkang Medical Research Co., Ltd.

Completed

A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China

Pneumonia | Adenocarcinoma | Small Cell Lung Cancer | Chronic Obstructive Pulmonary Disease | Non-Small Cell Lung Cancer | Lung Cancer | Tuberculosis | Chronic Bronchitis | Squamous Cell Carcinoma | Lung Neoplasm | Respiratory Tract Infection | Acute Bronchitis | Adenosquamous Carcinoma | Large Cell Carcinoma | Sarcomatoid... and other conditions

China
Canadian Cancer Trials Group
National Health and Medical Research Council, Australia; Dutch Society of Physicians... and other collaborators

Active, not recruiting

Double Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLC

Non-Small Cell Lung Cancer

Canada, United States, France, Spain, Taiwan, China, Australia, Italy, Japan, Singapore, Korea, Republic of, New Zealand, Netherlands, Romania, Bulgaria, Brazil, Hungary, Poland, Ukraine
Pierre Fabre Medicament

Active, not recruiting

Phase II Study Investigating the Combination of Encorafenib and Binimetinib in BRAF V600E Mutated Chinese Patients With Metastatic Non-Small Cell Lung Cancer (OCEANII)

Non-Small Cell Lung Cancer

China, Taiwan
GlaxoSmithKline

Completed

An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis

Tuberculosis

South Africa
National Institutes of Health Clinical Center (CC)

Completed

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Healthy Volunteers

United States
National Institute of Allergy and Infectious Diseases...
University of Pennsylvania; Emory University; University of Florida; Aurum Institute

Completed

A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutin (IMPACT-TB)

Tuberculosis

United States
University of California, San Francisco
Boston University; Boston Medical Center; Mbarara University of Science and Technology

Completed

Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT) (ADEPTT)

HIV/AIDS | Tuberculosis | Alcohol Abuse

Uganda
Federal University of Mato Grosso
Stanford University; Oswaldo Cruz Foundation

Withdrawn

BCG Re-vaccination for Primary Tuberculosis Prophylaxis in the Prison Population (PPT-BCG)

Latent Tuberculosis

Brazil

Search clinical trials for: Drug-resistant tuberculosis

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