Search clinical trials for: Non-Randomized Controlled Trials as Topic

Total 474204 results

University of Southern California
Health Research Association

Terminated

Oral Carnitine for Cramps in Pregnancy

Muscle Cramp

United States
University of Toronto
Canadian Institutes of Health Research (CIHR); Canadian Diabetes Association; The Physicians' Services Incorporated Foundation and other collaborators

Unknown

Meta-analyses of the Effect of 'Catalytic' Doses of Fructose and Its Epimers on Carbohydrate Metabolism

Obesity | Overweight | Metabolic Syndrome | Type 2 Diabetes | Prediabetes | Dysglycemia

Canada
Quark Pharmaceuticals

Completed

Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG)

Glaucoma, Angle-closure, Primary, Acute

Singapore, United States, Vietnam
University of Alabama at Birmingham
GlaxoSmithKline

Terminated

Study of Arixtra (Fondaparinux Sodium) to Prevent Blood Clots in Women Undergoing Abdominopelvic Surgery for Likely Gynecologic Malignancy

Venous Thrombosis

United States
Global Alliance for TB Drug Development
Sanofi; University College, London; European and Developing Countries Clinical... and other collaborators

Completed

Controlled Comparison of Two Moxifloxacin Containing Treatment Shortening Regimens in Pulmonary Tuberculosis (REMoxTB)

Pulmonary Tuberculosis

China, Zambia, Tanzania, India, Kenya, Malaysia, Mexico, South Africa, Thailand
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Pyridoxine and Topical Urea/Lactic Acid-Based Cream in Preventing Hand-Foot Syndrome in Patients Receiving Capecitabine for Breast Cancer or Other Cancer

Breast Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Drug/Agent Toxicity by Tissue/Organ

United States
Ministry of Health, Brazil
Financiadora de Estudos e Projetos

Terminated

Cell Therapy in Chagas Cardiomyopathy

Chagas Cardiomyopathy

Brazil
Ministry of Health, Brazil
Financiadora de Estudos e Projetos

Completed

Cell Therapy In Dilated Cardiomyopathy

Dilated Cardiomyopathy

Brazil
King Faisal Specialist Hospital & Research Center

Completed

Interaction Between Drug and Placebo Effect:Randomized Placebo Controlled Trials May Not be Accurate in Determining Drug Effect Size

Placebo Effect | Placebo Drug Interaction

Saudi Arabia
LEO Pharma

Completed

LEO 80185 in the Treatment of Psoriasis Vulgaris on the Non-scalp Regions of the Body (Trunk and/or Limbs)

Psoriasis Vulgaris

United States
AstraZeneca
Bristol-Myers Squibb

Completed

A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes and Inadequately Controlled Hypertension on an Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker

Type 2 Diabetes

Mexico, Russian Federation, Spain, United States, Canada, Puerto Rico, Hungary, Peru, Romania, Poland, Germany, Czech Republic, India, Colombia, Denmark, Finland
Maastricht University Medical Center
KCI medical B.V

Completed

A Randomised Controlled Trial Comparing Vacuum Assisted Closure (V.A.C.®) With Modern Wound Dressings

Leg Ulcer

Netherlands
Pfizer

Completed

A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee (ITIC)

Osteoarthritis

United States, Argentina, Czech Republic, Slovakia, Spain, Belgium, Canada, Peru, Germany, Hungary, Australia, Italy, Poland, Russian Federation
AstraZeneca
Bristol-Myers Squibb

Completed

A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes With Inadequately Controlled Hypertension on an ACEI or ARB and an Additional Antihypertensive Medication

Type 2 Diabetes

Australia, United States, Canada, Mexico, Puerto Rico, Germany, Hungary, Ireland, Poland, Romania, Denmark, Czech Republic, India, Colombia, Finland, United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Topical Sunscreen in Preventing Skin Rash in Patients Receiving Drugs Such as Erlotinib or Cetuximab for Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Dermatologic Complications

United States
H. Lundbeck A/S

Completed

Efficacy and Tolerability of Escitalopram and Duloxetine in Outpatients With Major Depressive Disorder

Major Depressive Disorder
Novartis Vaccines

Completed

Phase 2, Observer-Blind, Placebo-Controlled, Randomized, Multi-Center Extension Study to Evaluate the Safety and Immunogenicity of a Booster Dose of a MenABCWY Vaccine Administered 24 Months Following the Primary Series to Adolescents and Young Adults Who Participated in V102_03 (NCT01272180)

Meningococcal Disease

United States, Poland
Mike Hsu
Blue Care Network of Michigan; St. John Providence Hospital

Completed

Healing Through Affective Self-Awareness in Fibromyalgia: a Randomized Controlled Trial

Fibromyalgia

United States
DUSA Pharmaceuticals, Inc.

Completed

Twelve Month Follow-Up of CP0108

Actinic Keratosis

United States
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

A Trial of Postoperative Whole Brain Radiation Therapy vs. Salvage Stereotactic Radiosurgery Therapy for Metastasis

Neoplasm Metastasis | Brain Neoplasms

Japan
Armata Pharmaceuticals, Inc.
Walter Reed Army Institute of Research (WRAIR)

Completed

Ascending Dose Study of the Safety of AB-SA01 When Topically Applied to Intact Skin of Healthy Adults

Healthy Volunteers

United States
University of Göttingen
Medical University of Graz; German Research Foundation; Hannover Medical School; University of Cologne and other collaborators

Completed

Effects of a Psychotherapy Intervention in Depressed Patients With Coronary Artery Disease (SPIRR-CAD)

Depression | Coronary Artery Disease

Germany
Frontier Biotechnologies Inc.

Completed

A Study of a Topical Patch (AB001) in Patients With Chronic Low Back Pain

Chronic Low Back Pain

United States
Pfizer

Terminated

An Outpatient Study Of The Efficacy, Safety, And Tolerability Of PF-02545920 In The Adjunctive Treatment Of Sub-Optimally Controlled Symptoms of Schizophrenia

Schizophrenia

United States
University of Alberta
Alberta Health services

Completed

Supportive Text Messages to Reduce Mood Symptoms and Problem Drinking- Randomised Controlled Pilot Trials

Depression | Alcoholism

Canada
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Cardiff University; Northern... and other collaborators

Terminated

A Multicentre randomiSed Controlled TRial of IntraVEnous Immunoglobulin Versus Standard Therapy for Transverse Myelitis (STRIVE)

Neuromyelitis Optica | Myelitis, Transverse

United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Colorectal Cancer Metastatic to the Liver

Colorectal Cancer | Metastatic Cancer

United States
Rigel Pharmaceuticals

Completed

Safety and Efficacy of Topical R333 in Patients With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE) Lesions (SKINDLE)

Lupus Erythematosus, Systemic | Lupus Erythematosus, Discoid

United States, Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Hodgkin's Lymphoma

Lymphoma

United States, Puerto Rico
The First Affiliated Hospital of Henan University...
The First Affiliated Hospital of Zhengzhou University; No. 150 Central Hospital... and other collaborators

Unknown

The Role of Different Cycles of Chemotherapy（Capecitabine-oxaliplatin） in Esophageal Chemoradiotherapy (DCOECRT)

Esophageal Neoplasms | Stage III Esophageal Squamous Cell Carcinoma

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Plasma Cell Neoplasm | Myeloproliferative Neoplasms

United States
University of Miami

Terminated

Study of the Use of Niaspan for Treatment of Dyslipidemia in Diabetic Nephropathy

Diabetes Mellitus, Type 2 | Kidney Failure, Chronic | Hyperlipidemia

United States
Guangdong Provincial People's Hospital

Unknown

The Therapeutic Effects of Insulin and Berberine on Stress Hyperglycemia

Hyperglycemia

China
Chengdu University of Traditional Chinese Medicine
Hunan University of Traditional Chinese Medicine

Completed

Effect of Acupuncture on Patients With Mild Hypertension (EAPMH)

Essential Hypertension

China
Pfizer

Completed

5% Topical Ibuprofen (IBU) for Ankle Sprain

Ankle Injuries

United States
John Sievenpiper
Canadian Institutes of Health Research (CIHR); Canadian Diabetes Association; The Physicians' Services Incorporated Foundation and other collaborators

Unknown

Meta-analyses of the Effect of Liquid Meal Replacements on Cardiometabolic Risk

Obesity | Overweight | Type 2 Diabetes

Canada
Translational Research Center for Medical Innovation...
National Cerebral and Cardiovascular Center; Ministry of Health, Labour and... and other collaborators

Completed

Carotid Intima-media Thickness in Japan Statin Treatment Against Recurrent Stroke(J-STARS Echo)

Ischemic Stroke

Japan
Translational Research Center for Medical Innovation...
Osaka University; Ministry of Health, Labour and Welfare, Japan; Hiroshima University

Completed

hsCRP in Japan Statin Treatment Against Recurrent Stroke (J-STARS hsCRP)

Ischemic Stroke

Japan
Yung Shin Pharm. Ind. Co., Ltd.
Changhua Christian Hospital

Completed

A Double-Blind, Randomized, Placebo-Controlled Study of Topical VDO for the Treatment of Herpes Simplex Labialis

Herpes Labialis

Taiwan
Eastern Hepatobiliary Surgery Hospital

Unknown

Surgical Resection Versus Percutaneous Local Ablative Therapy for Hepatocellular Carcinoma

Hepatocellular Carcinoma With CSPH

China
Eastern Hepatobiliary Surgery Hospital

Completed

Preoperative Pain Control in Liver Surgery Patients

Pain, Postoperative | Hepatocellular Carcinoma

China
Pfizer

Completed

A Study to Evaluate the Pharmacodynamic Effects of Single Oral Doses of PF-06648671 on β-Amyloid (Aβ) Concentrations in Cerebrospinal Fluid (CSF)

Healthy Subjects

United States
Sunovion

Completed

Safety and Efficacy of Eslicarbazepine Acetate Monotherapy in Subjects With Partial Epilepsy Not Well Controlled by Current Antiepileptic Drugs

Epilepsy With Simple or Complex Partial Onset Seizures

United States, Canada
International Food Policy Research Institute
United States Agency for International Development (USAID); Food and Nutrition... and other collaborators

Completed

Preventing Malnutrition in Children Under Two Years of Age Approach

Malnutrition

Burundi, Guatemala
Deacon Biosciences, Inc.
ORA, Inc.

Completed

A Phase 2, Open-Label, Randomized, Parallel Group, Placebo-Controlled, Single-Center Study to Assess Anti-microbial Efficacy and Safety of DCN01 Compared to Unisol® Following Topical Periocular Administration in Healthy Volunteers

Ocular Infection

United States
Rio de Janeiro State University
Universidade Federal do Rio de Janeiro; National Research Council, Brazil

Completed

Prevention of Excessive Weight Gain by Discouraging Students From Drinking Sodas

Overweight | Children
Johnson & Johnson Consumer and Personal Products...

Completed

A Controlled Study of an Herbal Topical Patch in Treating Osteoarthritis (OA) of the Knee

Osteoarthritis, Knee

China
University of California, San Francisco
National Cancer Institute (NCI); University of California, Los Angeles; University... and other collaborators

Completed

AANCART Research Project on Lay Health Workers and Asian Americans (AANCARTLHW)

Colorectal Cancer

United States
University of Liverpool
Liverpool University Hospitals NHS Foundation Trust

Completed

Comparison of Two Dental Techniques Used to Treat Teeth Which Have Become Infected or Painful Following Trauma

Periapical Periodontitis | Apexification | Pulp Necrosis | MTA | Apexogenesis | Pulp Revascularisation | Non-vital Immature Tooth

United Kingdom
Baudax Bio
Lotus Clinical Research, LLC

Terminated

Placebo-Controlled Evaluation of Intranasal Dexmedetomidine for Postoperative Analgesia Following Bunionectomy

Pain, Post-operative

United States

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