Search clinical trials for: SGK-1 inhibitor

Total 103590 results

Radboud University Medical Center

Terminated

Pharmacokinetics of Atazanavir /Dolutegravir/Lamivudine Regimen as Maintenance Regimen (PRADAII)

HIV-1 Infection

Netherlands, Germany
Gilead Sciences

Completed

Safety and Efficacy of Bictegravir + Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Alafenamide in HIV-1 Infected, Antiretroviral Treatment-Naive Adults

HIV-1 Infection

United States
Azienda Ospedaliera Universitaria Senese
Catholic University of the Sacred Heart; Ospedale Policlinico San Martino; Azienda... and other collaborators

Unknown

Neurological Monitoring in Patients Switching From Dolutegravir Based Regimen to Bictegravir Based Regimen (DOBINeuro)

HIV-1-infection

Italy
Gilead Sciences

Completed

Study to Evaluate Switching From a Regimen Consisting of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate (EFV/FTC/TDF) Fixed Dose Combination (FDC) to Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) FDC in Virologically-Suppressed, HIV-1 Infected Adults

HIV-1 Infection

Spain, United States, United Kingdom, Switzerland, Germany, Canada, France, Belgium, Puerto Rico
University Hospital Virgen de las Nieves

Unknown

Real Life Study of Dolutegravir Plus Lamivudine in HIV-1-Infected Treatment-Naive Patients (DOLAVI)

HIV-1-infection

Spain
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure (MULTI-OCTAVE)

HIV-1 Infection

Kenya, Brazil, South Africa, Uganda, Zimbabwe, India, Malawi, Haiti, Thailand, Peru
Centre de Recherches et d'Etude sur la Pathologie...
INSERM UMR S 1136

Completed

Study Evaluating the Efficacy of a Reduced Dose Atazanavir in HIV-1-infected Patients (ATALOW)

HIV-1 Infection

France
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Evaluating Pharmacokinetic Interactions With Vaginal Ring Contraceptives and ART

HIV-1 Infection

United States, Peru, Puerto Rico, Brazil, Botswana, Kenya, South Africa, Thailand
Pfizer
ViiV Healthcare

Terminated

A Long Term Safety Study Of Lersivirine For The Treatment Of HIV-1 Infection In Subjects Who Have Completed Treatment With Lersivirine In Studies A5271015 And A5271022

HIV-1

South Africa, Australia, United Kingdom, Canada, Italy, Poland, Switzerland, Mexico, Brazil
Gilead Sciences

Completed

Study to Evaluate Switching From a Regimen Consisting of the Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate Single-Tablet Regimen (STR) to the Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate STR

HIV-1 Infection

United States
Pfizer

Completed

Safety And Efficacy Of Rescriptor In Patients For Human Immunodeficiency Virus (HIV) Patients

HIV-1 Infection
Eli Lilly and Company

Completed

A Study of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque Psoriasis Naive to Systemic Treatment

Plaque Psoriasis

Germany
Eli Lilly and Company

Completed

A Study of LY3325656 in Healthy Participants and Participants With Type 2 Diabetes

Diabetes Mellitus, Type 2

Singapore
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effect of Itraconazole on the Way the Body Absorbs, Distributes, and Gets Rid of ACT-1004-1239 Given as a Single Dose of 10 mg to Healthy Male Subjects

Healthy

Portugal
Washington University School of Medicine
The Children's Investment Fund Foundation

Completed

Nutritional and Anti-infective Interventions for Malnutrition in Pregnancy (Beleuman Welbodi)

Nutrition Disorders | Pregnancy | Stunting | Malnutrition in Pregnancy

Sierra Leone
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

A Study to Define the ECG Effects of Lixivaptan Compared to Placebo and Moxifloxacin in Healthy Adult Men and Women: A Thorough ECG Study

Healthy

United States
Grifols Therapeutics LLC

Completed

Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency (SPARK)

Emphysema | Alpha 1-antitrypsin Deficiency (AATD)

United States
Johns Hopkins University

Withdrawn

Pre-Exposure Prophylaxis Dosing in Pregnancy to Optimize HIV Prevention (PREP-P)

Pregnancy | HIV-1-infection
Janssen R&D Ireland

Completed

A Trial With TMC278-TIDP6-C222 for Continued TMC278 Access in Patients Infected With Human Immunodeficiency Virus-1

HIV-1 Infection

United States, Australia, France, United Kingdom, China, Belgium, Germany, Spain, Argentina, Romania, South Africa, Canada, Denmark, Netherlands, Chile, Puerto Rico, Austria, Russian Federation, Thailand, Sweden, Taiwan
Gilead Sciences

Completed

Switching From a Tenofovir Disoproxil Fumarate (TDF) Containing Regimen to Elvitegravir/Cobicistat/Emtricitabine/ Tenofovir Alafenamide (E/C/F/TAF) Fixed-Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Infected Adults Aged ≥ 60 Years

HIV-1 Infection

Spain, United Kingdom, Italy, France, Belgium
Makerere University
University of Pittsburgh; University of Nebraska; University of Liverpool

Unknown

Darunavir and Rilpivirine Interactions With Levonorgestrel Implant (DRIVE-2)

Contraception | HIV-1-infection

Uganda
Bionor Immuno AS
Celgene Corporation

Completed

Vacc-4x + Lenalidomide vs. Vacc-4x +Placebo in HIV-1-infected Subjects on Antiretroviral Therapy (ART) (IMID)

HIV-1 Infection

Germany
Bristol-Myers Squibb

Terminated

Safety, Efficacy and Dose-response Study of BMS-986001 in Subjects With HIV-1 Infection Who Are Treatment-naive

HIV-1 Infection

Thailand, United States, Australia, Canada, Spain, Colombia, South Africa, Hungary, France, Peru, Argentina, Chile, Mexico
Nantes University Hospital

Completed

Multicentric Open-label Study of Switch From Abacavir/Lamivudine Fixed Dose Combination Plus Nevirapine to Abacavir/Lamivudine/Dolutegravir in Virologically Suppressed HIV-1 Infected Adults (SWAD) (SWAD)

HIV-1 Infection

France
Kirby Institute

Completed

MARCH Central Nervous System Substudy

HIV-1 Infection

Argentina, Thailand, United Kingdom
Hospitales Universitarios Virgen del Rocío

Completed

Etravirine Plus 2 Analogs in HIV-infected Patients

HIV-1-infection

Spain
Activ'inside
CIC Inserm 1405, University Hospital Clermont-Ferrand, France

Completed

Acute Effect of a Proprietary Botanical Blend Rich in Polyphenols on Flow-mediated Dilation in Healthy Subjects

Healthy

France
B.P. Koirala Institute of Health Sciences

Completed

Association Between Preoperative Shock Index and Hypotension After Spinal Anaesthesia for Non- Elective Caesarean Section

Hypotension

Nepal
B.P. Koirala Institute of Health Sciences

Completed

Scoring System in Predicting Perforated Duodenal Ulcer Morbidity and Mortality in Bpkihs

Perforated Duodenal Ulcer

Nepal
MC2 Therapeutics

Completed

This Trial is a Randomised, Multicentre, Investigator-blind, Vehicle and Comparator-controlled, Parallel-group Trial With the Purpose of Evaluation Efficacy, Safety and Convenience of the MC2-01 Cream

Psoriasis Vulgaris

Germany, Czechia
Universidad de Granada
Hospital Clinico Universitario San Cecilio; Centro de Investigación Biomédica; Instituto Mixto Universitario Deporte y Salud and other collaborators

Completed

Effects of an Exercise Program on Cognition and Brain in Overweight/Obese Preadolescent Children (ActiveBrains)

Obesity | Overweight | Mental Health Wellness 1 | Cognitive Function 1, Social
Eli Lilly and Company

Active, not recruiting

A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

Healthy | Overweight | Obese

United States
University of Bucharest

Recruiting

Support Groups in the Metaverse for Ukrainian Refugees (METASUPUKR)

Mental Health Wellness 1 | Well-Being, Psychological

Romania
Tung Wah College
Chinese University of Hong Kong; Pok Oi Hospital; Golden Age Foundation

Not yet recruiting

Virtual Reality for Mental Well-being in Older People With Physical Disabilities

Mental Health Wellness 1 | Physical Disability
University of Sao Paulo
Harvard School of Public Health (HSPH)

Completed

Home Visiting Programs to Improve Early Childhood Development and Maternal Mental Health

Mental Health Wellness 1 | Child Development
Kaiser Permanente
Unity Health

Active, not recruiting

Park Rx and Physical Activity Among Low-income Children (ParkRx)

Physical Activity | Mental Health Wellness 1

United States
Mayo Clinic
Whole Vine Products

Completed

Effects of Chardonnay Seed Flour on Vascular Health

1. Endothelial Dysfunction (EndoPAT Score <=2)

United States
The University of Hong Kong

Active, not recruiting

A Guided Mobile-Based Perinatal Mindfulness Intervention

Psychological Distress | Mental Health Wellness 1

Hong Kong
Pedreira, Érika, M.D.

Completed

Sensorimotor Exercises in Virtual Reality Platform in Individuals With Human T-lymphotropic Virus

HTLV-1

Brazil
Ipsen

Terminated

IGF-1, IGFBP3, ALS Normative Ranges in Healthy Pediatric Spanish Population (EDISON)

IGF-1 Deficiency

Spain
ASLAN Pharmaceuticals

Recruiting

Investigate the Efficacy and Safety of Farudodstat Compared With Its Placebo in Adult Alopecia Areata Participants (FAST-AA)

Alopecia Areata

United States
DICE Therapeutics, Inc., a wholly owned subsidiary...

Completed

A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants

Healthy Participants

United States
Almirall, S.A.

Completed

Patient and Clinician Reported Outcomes for Tirbanibulin Effectiveness and Safety in Actinic Keratosis (PROAK)

Keratosis, Actinic

United States
Esperion Therapeutics, Inc.
Medpace, Inc.

Completed

Evaluation of ETC-1002 in Participants With Hypercholesterolemia and Hypertension

Hypertension | Hypercholesterolemia

United States
Takeda

Completed

Bioequivalence Study of Dexlansoprazole Capsules From Two Manufacturing Plants

Healthy Volunteers

United States
Celgene

Completed

Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A

Healthy Volunteer

United States
Huashan Hospital
Wenling No.1 People's Hospital, China

Unknown

Short Course Rifapentine and Isoniazid for the Preventive Treatment of Tuberculosis(SCRIPT-TB) (TB)

Silicosis Tuberculosis

China
Andrzej Frycz Modrzewski Krakow University
Karolinska Institutet; University of Rzeszow

Completed

Polish Validation 4AT Tool

Delirium, Postoperative | Surgical Procedure

Poland
Activ'inside
CIC Inserm 1405, University Hospital Clermont-Ferrand, France

Completed

Bioavailabity of the Major Metabolites of a Botanical Extract, in Healthy Adults

Healthy

France
Rajesh Deshar

Completed

Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia

Hemodynamic Instability | Effect of Drug | Post-spinal Hypotension | Glycopyrrolate

Nepal

3

Subscribe