Search clinical trials for: Severe uncontrolled asthma

Total 16728 results

Boston Scientific Corporation

Completed

Bronchial Thermoplasty in Severe Persistent Asthma (PAS2)

Severe Asthma

United States, Canada
Karolinska Institutet
Imperial College London; Jagiellonian University; Università degli Studi di Ferrara and other collaborators

Active, not recruiting

Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease (BIOAIR)

Asthma | COPD

Sweden
AstraZeneca

Completed

Characterisation of Patients With Severe Asthma in Primary and Secondary Care Settings in Europe Reported to be Eligible for Biological Therapy (RECOGNISE)

Severe Asthma

Hungary, Germany, Bulgaria, Czechia, France, Greece, Italy, Netherlands, Poland, Romania, Slovenia, Spain
KoBioLabs
Novotech (Australia) Pty Limited

Completed

Study of Multiple Ascending Dose of KBL693 in Healthy Participants

Moderate to Severe Asthma

Australia
Hopital Foch

Unknown

Evaluation of the Response to Monoclonal Antibody Therapy in Severe Asthma: Research of Predictive Biomarkers in Exhaled Air (Zina-VOC)

Asthma

France
Johns Hopkins University

Completed

Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposis

Chronic Rhinosinusitis (Diagnosis) | Nasal Polyps | Eosinophilia

United States
Boston Scientific Corporation

Completed

Research in Severe Asthma (RISA) Trial

Asthma
AB Science

Completed

Masitinib in Treatment of Patients With Severe Persistent Asthma Treated With Oral Corticosteroids

Asthma

Spain, Bulgaria, Czechia, France, Hungary, India
LEO Pharma

Completed

Tralokinumab in Combination With Topical Corticosteroids for Moderate to Severe Atopic Dermatitis - ECZTRA 3

Atopic Dermatitis

United States, Germany, Belgium, Canada, Spain, United Kingdom, Poland, Netherlands
NYU Langone Health
National Institute for Occupational Safety and Health (NIOSH/CDC)

Completed

Uncontrolled Lower Respiratory Symptoms in the WTC Survivor Program

Lung Diseases | Medication Compliance

United States
Boston Scientific Corporation

Completed

RISA Extension Study - Long Term Safety

Asthma

Canada, Brazil, United Kingdom
Boston Scientific Corporation

Withdrawn

Safety of Bronchial Thermoplasty Performed With the Alair® System During Two Treatment Sessions to Treat Severe Asthma (3to2)

Asthma
AstraZeneca

Completed

Prevalence of the Eosinophilic Phenotype Among Severe Asthma Patients (PREPARE)

Severe Asthma

Mexico, Argentina, Chile, Saudi Arabia, Colombia, Costa Rica
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Unknown

Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-5 Humanized Monoclonal Antibody Injection

add-on Maintenance Treatment of Patients With Severe Eosinophilic Asthma

China
Mundipharma Korea Ltd

Terminated

Efficacy and Safety of Flutiform K-haler in Patients With Uncontrolled Asthma Following Mid-dose ICS/LABA DPI Therapy (SWIFT)

Asthma

Korea, Republic of
Pfizer

Completed

Study Evaluating Efficacy and Safety of PF-04965842 and Dupilumab in Adult Subjects With Moderate to Severe Atopic Dermatitis on Background Topical Therapy (JADE Compare)

Skin Diseases | Immune System Diseases | Hypersensitivity | Hypersensitivity, Immediate | Genetic Diseases, Inborn | Skin Diseases, Genetic | Dermatitis | Eczema | Skin Diseases, Eczematous | Dermatitis, Atopic

Spain, Taiwan, United States, Australia, Poland, Germany, Hungary, Bulgaria, Czechia, Japan, Korea, Republic of, Latvia, Canada, United Kingdom, Mexico, Chile, Slovakia, Italy
University Hospital Plymouth NHS Trust
University of Plymouth

Completed

National Validation and Sensitivity to Change of the SAQ

Asthma | Severe Asthma

United Kingdom
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Omalizumab in Severe Japanese Cedar Pollinosis Adult and Adolescent Patients

Seasonal Allergic Rhinitis

Japan
Queen Mary University of London

Unknown

Identification of Autoantigens in EGPA and Severe Eosinophilic Asthma (IDEA)

Eosinophilic Esophagitis | Churg-Strauss Syndrome | Eosinophilic Asthma | Eosinophilic Pneumonia

United Kingdom
GlaxoSmithKline

Terminated

GSK2190915 Moderate to Severe Asthma Study

Asthma

United Kingdom, Canada
Washington University School of Medicine
University of Alabama at Birmingham; University of Chicago; The Cleveland Clinic and other collaborators

Completed

A Prospective Observational Study of Biopredictors of Bronchial Thermoplasty Response in Patients With Severe Refractory Asthma (BTR Study) (BTR)

Asthma

United States
GlaxoSmithKline

No longer available

This Record Contains Information About the Mepolizumab Compassionate Use (CU) Product Activities: 104317: CU and Long-Term Access Study of Mepolizumab in HES. 201956:A Long-term Access Programme for Subjects With Severe Asthma 112562: Expanded Access for Patients With Hypereosinophilic

Hypereosinophilic Syndrome
University of Giessen
Activaero GmbH

Terminated

Inhaled Steroids and Control of Severe Asthma (INHALE)

Severe Persistent Asthma

Germany
University Hospital, Toulouse
AstraZeneca

Unknown

National Survey on Care Pathway and Quality of Life in Patients With Severe Asthma According to Their Phenotype. (2ndsouffle)

Severe Asthma | Asthma Chronic

France
Università degli Studi di Ferrara

Completed

Effects of Anti-IL5 Biological Treatments on Blood IgE Levels in Severe Asthmatic Patients (BIONIGE)

Asthma | Asthma; Eosinophilic

Italy
University of Nottingham

Unknown

Poor Response to Monoclonal Therapy in Asthma (PROCLAIM)

Asthma

United Kingdom
GlaxoSmithKline

Terminated

Repeat Dose Study of GSK3772847 in Participants With Moderate to Severe Asthma With Allergic Fungal Airway Disease (AFAD)

Asthma

France, Netherlands, Russian Federation, United Kingdom
University of Newcastle, Australia
GlaxoSmithKline

Unknown

Comparing Treatment Efficacy With Mepolizumab and Omalizumab in Severe Asthma - "Choosebetweenamab".

Asthma | Eosinophilic Asthma

Australia
Washington University School of Medicine

Unknown

Washington University Severe Asthma Research Program III (WU SARPIII)

Asthma

United States
University Hospital, Bordeaux

Completed

Preschool Bronchial Remodeling and Risk of Exacerbation (RESPIRE)

Preschool Severe Asthma

France
Shiraz University of Medical Sciences

Unknown

Comparison of Montelukast and Azelastine in Treatment of Moderate to Severe Allergic Rhinitis

Allergic Rhinitis

Iran, Islamic Republic of
Hae-Sim Park
Novartis Korea Ltd.

Completed

Factors for Predicting Severe Asthma Exacerbators in Adult Asthmatics: A Real Word- Effectiveness Study

Asthma

Korea, Republic of
GlaxoSmithKline
Quintiles IMS

Completed

Prevalence of Severe Asthma in Spanish Hospitals

Asthma

Spain
AstraZeneca

Completed

Assessment of Treatment Patterns of Severe Asthmatic Patients Across the Gulf Region - SevEos Study (SevEos)

Severe Asthma

United Arab Emirates, Oman
AstraZeneca
Medical Writer: Dr. Rodrigo Athanazio; CRO: CTI-Eurotrials

Completed

BRazilian Asthmatics Patients EOSinophilic Profile (BRAEOS) (BRAEOS)

Severe Asthma

Brazil
Chiesi Farmaceutici S.p.A.

Completed

Efficacy and Tolerability of Beclometasone/Formoterol Single Inhaler in Patients With Moderate to Severe Persistent Asthma

Asthma
University Hospital, Montpellier

Unknown

Anti-IL5 and Other Biotherapies in Cystic Fibrosis (MAB-CF)

Cystic Fibrosis

France
Oman Medical Speciality Board

Unknown

Double Dose Magnesium Sulphate in Moderate-severe Asthma in Paediatrics

Asthma in Children
Belfast Health and Social Care Trust
Hoffmann-La Roche; Medical Research Council; Aerocrine AB

Completed

A Pragmatic Trial of Corticosteroid Optimisation in Severe Asthma

Severe Persistent Asthma

United Kingdom
Dubai Health Authority
McGill University

Completed

Vitamin D Regulates the Expression of Glucocorticoid Receptors in Blood of Severe Asthmatic Patients (VitaminD)

Effect of Drug
Neutec Ar-Ge San ve Tic A.Ş

Completed

Comparison of 24 Hour Bronchodilator Efficacy of Tiotropium 18 mcg Delivered Via DISCAIR Versus SPIRIVA 18 µg Delivered Via HANDIHALER® in Patients With Moderate to Severe COPD

COPD
Neutec Ar-Ge San ve Tic A.Ş

Completed

Efficacy and Safety Study of Acetylcysteine/Doxofylline 1200/400 mg Effervescent Tablet in the Treatment of Moderate-Severe COPD.

COPD

Turkey
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of QAW039 in Patients With Severe Asthma Inadequately Controlled With Standard of Care Asthma Treatment.

Asthma

Germany, United States, Belgium, Poland, Romania, Estonia, Australia, Austria, France, Switzerland, United Kingdom, Latvia, Lithuania, Guatemala, Brazil, Argentina, Philippines, China, Singapore, Finland, Hungary, Greece, Ireland, Vie... and more
Rhode Island Hospital
American Lung Association

Terminated

Inhaled Steroids at Discharge After Emergency Department Visits for Children With Uncontrolled Asthma

Asthma

United States
Amgen

Completed

Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate-to-Severe Plaque-Type Psoriasis (Core Study)

Psoriasis | Plaque-type Psoriasis

United States, Canada
Nicholas Kenyon
National Heart, Lung, and Blood Institute (NHLBI)

Completed

L-arginine in Severe Asthma Patients Grouped by Exhaled Nitric Oxide Levels

Inflammation | Asthma

United States
Pfizer

Completed

Study Evaluating Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis (JADE Mono-2)

Dermatitis, Atopic

China, United States, Australia, Poland, Hungary, Korea, Republic of, Germany, Bulgaria, Canada, Czechia, Japan, Latvia, United Kingdom
NorthShore University HealthSystem

Completed

The Use of the Propeller Health Platform to Improve Inhaled Corticosteroid (ICS) Use Among Adults With Uncontrolled Persistent Asthma

Asthma

United States
NHS Greater Glasgow and Clyde
Queen's University, Belfast

Completed

Inflammation Following Mepolizumab and Oral Corticosteroids in Asthma (MAPLE)

Asthma

United Kingdom
GlaxoSmithKline

Completed

Efficacy and Safety Study of GSK3772847 in Subjects With Moderately Severe Asthma

Asthma

United States, Canada, Russian Federation, Mexico, Australia, Ukraine

Search clinical trials for: Severe uncontrolled asthma

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