Search clinical trials for: Tenofovir

Total 1149 results

National Institute of Allergy and Infectious Diseases...
Microbicide Trials Network

Completed

Safety and Effectiveness of TFV 1% Gel, TDF Tablets, and FTC/TDF Tablets in Preventing HIV in Women

HIV Infections

South Africa, Uganda, Zimbabwe
Public Health Foundation Enterprises, Inc.
National Institute of Mental Health (NIMH); Emory University; San Francisco Department... and other collaborators

Completed

DOT Diary Optimization Pilot: A Pilot Study to Optimize the DOT Diary App to Measure PrEP Adherence

Risk Behavior | HIV Prevention | Adherence, Medication | Pre-Exposure Prophylaxis

United States
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Doravirine, Tenofovir, Lamivudine (MK-1439A) in Participants Infected With Treatment-Naïve Human Immunodeficiency Virus (HIV) -1 With Transmitted Resistance (MK-1439A-030) (DRIVE BEYOND)

HIV-1 Infection
National Institute of Allergy and Infectious Diseases...

Completed

Tenofovir Gel in Pregnancy and Lactation

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Blood Levels of Tenofovir Gel in HIV Uninfected Pregnant Women Planning Cesarean Delivery

HIV Infections

United States
AIDS Clinical Trials Group
National Cancer Institute (NCI); National Institute of Allergy and Infectious... and other collaborators

Completed

Three Chemo Regimens as an Adjunct to ART for Treatment of Advanced AIDS-KS

HIV-1 Infection

South Africa, Brazil, Zimbabwe, Kenya, Malawi, Uganda
National Institute of Allergy and Infectious Diseases...
Microbicide Trials Network

Completed

Adherence and Acceptability to and Blood Levels of Tenofovir Gel and Tablets in HIV Uninfected Women

HIV Infections

United States, Uganda, South Africa
Nguyen Thi Trieu, MD

Approved for marketing

Treatment on HBeAg Positive or HBeAg Negative in Chronic Hepatitis B (HBV)

CHRONIC HEPATITIS B

Vietnam
Frontier Biotechnologies Inc.

Completed

Test Albuvirtide in Experienced Patients (TALENT)

HIV Infections | AIDS

China
Assistance Publique - Hôpitaux de Paris

Completed

Placental Transfer of Tenofovir (TDF-PTP)

Pregnant Women

France
Fudan University

Active, not recruiting

Tenofovir Alafenamide for HBV Prophylaxis in Post Orthotopic Liver Transplant

HBV | POST LIVER TRANSPLANT

China
Philadelphia Fight
Gilead Sciences

Completed

Validation of a Urine Assay to Measure Tenofovir Levels in Patients Taking Tenofovir Alafenamide

Hiv

United States
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Alafenamide (TAF) From Tenofovir Disoproxil Fumarate (TDF) and/or Other Oral Antiviral Treatment (OAV)

Chronic Hepatitis B

United States, Hong Kong, Korea, Republic of, Taiwan, United Kingdom, Canada, New Zealand, Italy
University of California, San Diego
University of California, Los Angeles; GlaxoSmithKline; University of Southern... and other collaborators

Completed

Viral Dynamics and Pharmacokinetics of Abacavir and Tenofovir

HIV Infections

United States
University of Washington
Bill and Melinda Gates Foundation

Completed

PrEP in Breastfeeding Study

HIV Pre-exposure Prophylaxis During Breastfeeding

Kenya, Uganda
Yale University
Gilead Sciences

Withdrawn

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects

Tuberculosis | Hiv

United States
Plan Nacional sobre el Sida (PNS)
Effice Servicios Para la Investigacion S.L.

Completed

Randomized Clinical Trial for the Prevention of SARS-CoV-2 Infection (COVID-19) in Healthcare Personnel (EPICOS)

Coronavirus Infection

Spain
Gilead Sciences

Completed

Study to Evaluate Switching From a Regimen of Two Nucleos(t)Ide Reverse Transcriptase Inhibitors (NRTI) Plus a Third Agent to a Fixed Dose Combination (FDC) of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF), in Virologically-Suppressed, HIV-1 Infected African American Participants (BRAAVE 2020)

HIV-1 Infection

United States
Humanity and Health Research Centre
Beijing 302 Hospital; Nanfang Hospital of Southern Medical University

Completed

DAAs Treatment for Chronic HCV/HBV Co-infection Patients(DASCO) (DASCO)

Chronic Hepatitis C Infection | Hepatitis B Reactivation | HBV Coinfection

China
ANRS, Emerging Infectious Diseases
UNITAID; Institut de Recherche pour le Developpement

Completed

Efficacy and Safety of a Dolutegravir-based Regimen for the Initial Management of HIV Infected Adults in Resource-limited Settings (NAMSAL)

HIV-1 Infection

Cameroon
Emory University
Centers for Disease Control and Prevention

Completed

Body Compartment Pharmacokinetics of Anti-retroviral Agents That May be Considered for Future On-demand Peri-exposure HIV Prophylaxis Regimens

HIV/AIDS

United States
Universidad Nacional de Colombia
Hospital Universitario San Ignacio; Pontificia Universidad Javeriana; Fundación... and other collaborators

Completed

Effectiveness and Safety of Medical Treatment for SARS-CoV-2 (COVID-19) in Colombia

COVID-19

Colombia
University of Colorado, Denver

Completed

Effects of Sofosbuvir/Ledipasvir Treatment on the Pharmacokinetics and Renal Safety of Tenofovir

Hepatitis C and HIV Coinfection

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Study of Options for Second-Line Effective Combination Therapy (SELECT) (SELECT)

HIV-1 Infection

Peru, Kenya, Malawi, Brazil, South Africa, Zimbabwe, India, Thailand, Tanzania
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

FTC/RPV/TDF on T-Cell Activation, CD4+ T-Cell Count, Inflammatory Biomarkers and Viral Reservoir

HIV-1 Infection

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Bone, Immunologic, and Virologic Effects of a Antiretroviral Regimen

HIV-1 Infection

United States, Puerto Rico
Guy's and St Thomas' NHS Foundation Trust
Gilead Sciences; ViiV Healthcare

Completed

The Role of Home Packs of HIV PEPSE in High Risk Individuals (Home PEPSE)

HIV-1-infection

United Kingdom
Janssen Research & Development, LLC

Withdrawn

A Study of JNJ-56136379 in Healthy Participants

Healthy
Janssen Pharmaceutica N.V., Belgium

Completed

Study to Assess the Acceptability of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed-Dose Combination (FDC) Tablets in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Pediatric Participants, Using Matching Placebo Tablets

HIV-1

United States, Spain
University Hospital, Caen

Completed

Effect of Tenofovir/Emtricitabine in Patients Recently Infected With SARS-COV2 (Covid-19) Discharged Home (AR0-CORONA)

Covid19

France
CONRAD
National Institute of Allergy and Infectious Diseases (NIAID); National Institute...

Completed

Rectal Safety and Acceptability Study of Tenofovir 1% Gel

Rectal Microbicides

United States
CONRAD
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Coital Pharmacokinetics/Pharmacodynamics (PK/PD) of Tenofovir Gel

Pharmacokinetics of 1% Tenofovir Gel Following Coitus | Pharmacodynamics of 1% Tenofovir Gel Following Coitus

United States
CONRAD
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Tenofovir Levels Following Local Application of Tenofovir Reduced-Glycerin 1% Gel

HIV Prevention

United States
CONRAD
National Institute of Allergy and Infectious Diseases (NIAID); National Institute... and other collaborators

Completed

Safety and Acceptability Study of Oral Emtricitabine/Tenofovir Disoproxil Fumarate Tablet and Rectally-Applied Tenofovir Reduced-Glycerin 1% Gel

HIV

United States, South Africa, Peru, Puerto Rico, Thailand
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Tenofovir Rectal Douche to Prevent HIV Transmission (DREAM-03)

HIV/AIDS | HIV Prevention

United States
National Cheng-Kung University Hospital

Unknown

The Impact of Tenofovir Alafenamide on Profiles of Body Weight and Metabolic Features in Chronic Hepatitis B Patients. (HBV)

HBV

Taiwan
University of Maryland, Baltimore

Completed

A Study to Evaluate of the Efficacy of Enfuvirtide During the Induction Phase of Therapy

HIV Infections

United States
University of Maryland, Baltimore

Completed

Safety and Durability ofTenofovir and a Cell Cycle Agent for Viral Suppression (HADIT)

HIV Infections | AIDS

United States
University of California, San Francisco
San Francisco AIDS Foundation; California HIV/AIDS Research Program

Completed

Study of Truvada for HIV Pre Exposure Prophylaxis Using Daily Directly Observed Therapy to Look at Potential Interactions Between Truvada and Hormone Therapy (I-BrEATHe)

HIV Prevention | Transgender Health

United States
Hepatera Ltd.
Data Matrix Solutions

Completed

A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D

Chronic Hepatitis D Infection With Hepatitis B

Russian Federation, Germany
Indiana University

Completed

Assessment of a New "Boosting" Strategy for HIV Pre-exposure Prophylaxis in Healthy Volunteers

Pre-Exposure Prophylaxis

United States
Hepatera Ltd.

Completed

Myrcludex B in Combination With Peginterferon Alfa-2a Versus Peginterferon Alfa-2a Alone in Patients With Chronic Viral Hepatitis B With Delta-agent

Chronic Viral Hepatitis B With Delta-agent

Russian Federation
Public Health Foundation Enterprises, Inc.
University of California, San Francisco; California HIV/AIDS Research Program; San Francisco Department of Public Health and other collaborators

Completed

The Stay Study: A Demonstration Project Advancing PrEP Delivery in the San Francisco Bay Area Transgender Community

Transgender Persons | Pre-Exposure Prophylaxis

United States
Dong-A ST Co., Ltd.

Completed

Efficacy and Safety of DA-2802 in Chronic Hepatitis B Patients

Hepatitis B， Chronic

Korea, Republic of
Gilead Sciences

Completed

Study to Evaluate Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Positive Participants

HIV Infections | HIV

Canada, United States, Spain, Puerto Rico, France, Switzerland, Australia, Germany, United Kingdom, Sweden, Brazil, Austria, Thailand, Netherlands, Belgium, Dominican Republic, Portugal, Italy, Denmark, Mexico
Public Health Foundation Enterprises, Inc.
National Institute of Mental Health (NIMH); Emory University; San Francisco Department... and other collaborators

Completed

DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men

Risk Behavior | HIV Prevention | Adherence, Medication | Pre-Exposure Prophylaxis

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Hepatitis B Surface Antigen(HBsAg) Loss in Chronic Hepatitis B Patients With Low Viral Load (LVL)

Chronic Hepatitis B

Netherlands
Young-Suk Lim
Samsung Medical Center; Seoul National University Hospital; Korea University... and other collaborators

Completed

Switching From TDF to TAF vs. Maintaining TDF in Chronic Hepatitis B With Resistance to Adefovir or Entecavir.

Chronic Hepatitis b

Korea, Republic of
Hospital Nacional Carlos Alberto Seguin Escobedo...

Completed

Tenofovir-DF Versus Hydroxychloroquine in the Treatment of Hospitalized Patients With COVID-19 (TEDHICOV) (TEDHICOV)

Covid19 | SARS-CoV Infection | Tenofovir

Peru
Philip Grant
Gilead Sciences

Completed

Switch From Nevirapine-based Regimen to Once a Day Rilpivirine/Emtricitabine/Tenofovir (Near-Rwanda)

HIV

Rwanda

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