Search clinical trials for: antigen specificity

Total 2332 results

National University Hospital, Singapore

Recruiting

ALaCART-B: Acute Leukemia and Chimeric Antigen Receptor-T Cell Therapy for B-lymphoblastic Leukemia. (ALaCART)

Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR | CAR T-Cell-Related Encephalopathy Syndrome

Singapore
National Cancer Institute (NCI)

Recruiting

T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers

Kita-kyushu Lung Cancer Antigen 1, Human

United States
Zhejiang University
Yake Biotechnology Ltd.

Recruiting

A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Systemic Lupus Erythematosus

Autoimmune Diseases | Systemic Lupus Erythematosus

China
Central Hospital, Nancy, France

Not yet recruiting

Evaluation of Intradermal Hepatitis B Vaccine After IMIQUIMOD's Application, in Cirrhotics Who Did Not Respond to the Usual Vaccine Regimen (IDMODVHB)

Vaccine Reaction | HBV | Cirrhosis, Liver | Vaccination Failure
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung

Healthy | Latent Tuberculosis Infection (LTBI)

United States
Shanghai East Hospital

Not yet recruiting

Biparametric MRI in Prostate Cancer Screening: a Noninferior Randomized Controlled Study

Prostate Cancer

China
Sichuan University

Not yet recruiting

Tumor Antigen-sensitized DC Vaccine as an Adjuvant Therapy for Esophagus Cancer

Carcinoma | Esophagus Cancer

China
Pfizer

Recruiting

MagnetisMM-5: Study of Elranatamab (PF-06863135) Monotherapy and Elranatamab + Daratumumab Versus Daratumumab + Pomalidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma (MAGNETISMM-5)

Multiple Myeloma

China, Korea, Republic of, Taiwan, United States, France, Sweden, Australia, Japan, Spain, Czechia, United Kingdom, Canada, Germany, New Zealand, Italy, Poland, Netherlands, Austria, Mexico, Finland, Argentina, Belgium, Brazil, Greece, ... and more
Nkarta Inc.

Recruiting

NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers

Lymphoma, Non-Hodgkin | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | B-cell Acute Lymphoblastic Leukemia | Small Lymphocytic Lymphoma | Large B-cell Lymphoma | Indolent Lymphoma | Aggressive Lymphoma | Large-cell Lymphoma

United States, Australia
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; PPD; Rho Federal Systems Division, Inc.; Immune Tolerance...

Recruiting

Carfilzomib and Belatacept for Desensitization (ADAPT)

Highly Sensitized Prospective Kidney Transplant Recipients

United States
Diamyd Medical AB

Recruiting

A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes (DIAGNODE-3)

Type 1 Diabetes Mellitus

Czechia, Spain, United States, Hungary, Netherlands, Estonia, Germany, Poland, Sweden
Saglik Bilimleri Universitesi

Recruiting

Changing of Prostate Specific Antigen Value in Patients With Covid-19

Covid19 | Prostate Specific Antigen

Turkey
Sorrento Therapeutics, Inc.

Recruiting

Study to Assess Allogeneic Anti-CD38 A2 Dimeric Antigen Receptor T Cells in Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States
Wuhan Union Hospital, China

Recruiting

Clinical Application of 68Ga-PSMA PET/MR for Diagnosis and Staging in Hepatocellular Carcinoma

Malignant Neoplasm

China
Baylor College of Medicine
National Cancer Institute (NCI); Stand Up To Cancer; Center for Cell and Gene... and other collaborators

Recruiting

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

Sarcoma | Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma | HER-2 Protein Overexpression | Undifferentiated Sarcoma

United States
Ruijin Hospital
UTC Therapeutics Inc.

Recruiting

Anti-mesothelin CAR-T Cells With Advanced Refractory Solid Tumors (Amaretto)

Refractory Malignant Solid Neoplasm

China
M.D. Anderson Cancer Center

Recruiting

Rituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop Study

Diffuse Large B-Cell Lymphoma

United States
University of Alabama at Birmingham

Recruiting

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

Lymphoma, Non-Hodgkin | Multiple Myeloma | Acute Lymphoblastic Leukemia | Cytokine Release Syndrome | ICANS

United States
Catherine Bollard
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

HIV Antigen-specific T-cells Targeting Conserved Epitopes (HST-NEETs) BMTCTN1903 (BMTCTN1903)

HIV Associated Lymphoma

United States
The Affiliated Hospital of Xuzhou Medical University
Xuzhou Medical University

Recruiting

Clinical Study of CAIX-targeted CAR-T Cells in the Treatment of Advanced Renal Cell Carcinoma

Immunotherapy

China
Mount Carmel Health System
Mount Carmel Foundation

Recruiting

GGT and Uric Acid to Predict Gestational Diabetes Mellitus (GGTUAGDM)

Gestational Diabetes

United States
Second Affiliated Hospital of Guangzhou Medical...
Guangdong Zhaotai InVivo Biomedicine Co. Ltd.

Recruiting

Intratumor CpG-ODN Injection Boosters Immune Killing Against in Situ Tumor Antigen Release for Advanced Solid Tumors

Hepatocellular Carcinoma | Lung Cancer | Solid Tumor

China
University Hospital, Brest

Recruiting

Evaluation of the Sofia SARS Antigen FIA Assay for COVID-19 (ESADEC)

SARS-CoV2 Infection

France
National Taiwan University Hospital

Not yet recruiting

CD19 CAR T Cells in Children and Adults With Relapsed or Refractory CD19 Positive B Cell Malignancies

Relapsed/Refractory B-Cell Malignancies
Prof. Dr. med. Christian Gratzke
Merck Sharp & Dohme LLC

Recruiting

SRT in Combination With Pembrolizumab in Patients With Recurrent Prostate Cancer After Radical Prostatectomy (Pembro-SRT)

Urologic Cancer | Biochemical Recurrence of Malignant Neoplasm of Prostate

Germany
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Radiation Therapy to Immunotherapy for Stage IV Non-Small Cell Lung Cancer Patients Who Are PD-L1 Negative

Lung Adenocarcinoma | Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Lung Adenosquamous Carcinoma

United States
St Vincent's Hospital, Sydney

Recruiting

Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstruction (PICASSO)

Metastatic Prostate Cancer

Australia
920th Hospital of Joint Logistics Support Force...

Recruiting

Clinical Study of Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of Myeloid Leukemia

Acute Myeloid Leukemia

China
Masaryk University
Czech-BioImaging; Wroclaw University of Health and Sport Sciences

Recruiting

Neuroplasticity in Motor Learning in Young Adults Under Variable and Constant Practice Conditions (NMLPC)

Neuroplasticity in Motor Learning

Czechia
Ann-Sofie Backman
The Swedish Research Council

Recruiting

Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome (MesaCAPP)

Lynch Syndrome | Colon Cancer | Colon Neoplasm

Sweden, Denmark, Italy, Poland
Beckman Coulter, Inc.

Recruiting

Access HBV Assays - European Union (EU) Clinical Trial Protocol -

HBV

France
Inge Marie Svane
Technical University of Denmark

Recruiting

ImmPACT Expanded Multiple Antigen Specific Endogenously Derived T Cells (MASE-T) to Patients With Metastatic Melanoma

Malignant Melanoma

Denmark
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Baylor College of Medicine; Texas Children's... and other collaborators

Recruiting

HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma

Ependymoma

United States
Central Hospital, Nancy, France

Recruiting

Study of Risk Factors for Intraductal Papillary Mucinous Neoplasms Degeneration at the Nancy CHRU (IPMN) (IPMN)

Study of Risk Factors for IPMNs Degeneration at the Nancy CHRU

France
St. Jude Children's Research Hospital

Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

Melanoma | Soft Tissue Sarcoma | Carcinoma | Osteosarcoma | Ewing Sarcoma | Rhabdoid Tumor | Neuroblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Desmoplastic Small Round Cell Tumor | Pediatric Solid Tumor | Clear Cell Sarcoma | Malignant Peripheral Nerve Sheath Tumors | Adrenocortical Cancer | Germ Cell Cancer

United States
Mayo Clinic

Recruiting

Pemetrexed and Pembrolizumab for the Treatment of Recurrent and/or Metastatic Salivary Gland Cancer

Adenoid Cystic Carcinoma | Recurrent Salivary Gland Carcinoma | Stage IV Major Salivary Gland Cancer AJCC v8 | Metastatic Salivary Gland Carcinoma

United States
Chongqing Precision Biotech Co., Ltd

Recruiting

Phase I Study of pCAR-19B in the Treatment of Adult CD19-positive Relapsed/Refractory B-ALL

Acute Lymphoblastic Leukemia, in Relapse | Refractory Acute Lymphoblastic Leukemia

China
M.D. Anderson Cancer Center

Recruiting

Outcomes After Chimeric Antigen Receptor Therapy and Radiation Therapy for Hematologic Malignancies

Hematopoietic and Lymphoid Cell Neoplasm

United States
University Hospital Hradec Kralove

Recruiting

Dynamics of Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients

COVID-19 Respiratory Infection

Czechia
Plexision

Recruiting

Immunity After COVID-19 Vaccination

Immunity to COVID-19

United States
Fundación Huésped
ViiV Healthcare; Federal University of Bahia

Recruiting

Dolutegravir-Lamivudine for naïve HIV-Infected Patients With ≤200 CD4/mm3 (DOLCE)

HIV-1-infection

Brazil, Argentina
Cannabis Research Associates

Not yet recruiting

Study to Evaluate the Performance of the Therma COVID-19 Rapid Antigen Test for Detection of SARS-CoV-2

Covid19
Vilnius University

Recruiting

Analysis of Immunogenicity, Safety and Efficacy of COVID-19 Vaccines in Immunosuppressed Individuals

Hematologic Neoplasms | COVID-19 Vaccines

Lithuania
M.D. Anderson Cancer Center

Recruiting

Cardiovascular Events Among Adults Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma Treated With Standard of Care Chimeric Antigen Receptor T Cell Therapy

Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent Aggressive B-Cell Non-Hodgkin Lymphoma | Recurrent High Grade B-Cell... and other conditions

United States
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline; National Institute for Health Research, United Kingdom; Kidney... and other collaborators

Recruiting

PROphylaxis for paTiEnts at Risk of COVID-19 infecTion -V (PROTECT-V)

Covid19

United Kingdom
Nantes University Hospital
Roche Diagnostics

Recruiting

HE4 in the Diagnostic Approach of Endometrial Cancer in Patients With Postmenopausal Bleeding (METRODEC)

Endometrial Neoplasms | Uterine Hemorrhage | Postmenopause | Cancer Biomarker | CA 125 Antigen

France
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
The First Affiliated Hospital of Zhengzhou University

Not yet recruiting

Clinical Study of CD276 Targeted Autologous Chimeric Antigen Receptor T Cell Infusion in Patients With CD276 Positive Advanced Solid Tumor

Gastric Cancer | Lung Cancer | Osteosarcoma | Neuroblastoma
Lund University Hospital

Recruiting

Personalized Radiotherapy for Biochemical Recurrence of Prostate Cancer After Prostatectomy. (PROPER2)

Prostate Cancer

Sweden
Sohag University

Not yet recruiting

the Relationship Between Helicobacter Pylori Infection and Irritable Bowel Syndrome

Irritable Bowel Syndrome
Miltenyi Biomedicine GmbH
ICON plc

Recruiting

Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients (DALY 2-EU)

Diffuse Large B-cell Lymphoma

Spain, Germany, Netherlands, Belgium, France, Czechia, Austria, Lithuania, Sweden, Hungary, Italy, Poland

Search clinical trials for: antigen specificity

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