Search clinical trials for: dose titration study

Total 130749 results

The Fourth Affiliated Hospital of Zhejiang University...

Recruiting

A Dose Escalation and Dose Expansion Clinical Study of STI-7349 in Subjects With Advanced Solid Tumors

Advanced Solid Tumor

China
Neurodegenerative Disease Research Inc

Recruiting

Phase1 First in Human Ascending Dose Study to Evaluate the Safety and Tolerability of FC-12738 in Health Adults

Tolerance | Safety Issues

United States
Bausch Health Americas, Inc.

Not yet recruiting

Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis

Ulcerative Colitis
Keros Therapeutics, Inc.

Recruiting

A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).

Pulmonary Arterial Hypertension

United States, Australia, Germany, Korea, Republic of, Poland, Portugal, Spain, Taiwan, United Kingdom
Seoul National University Hospital

Recruiting

Dose Finding Study for Remimazolam in Children

Drug Effect

Korea, Republic of
Boehringer Ingelheim

Recruiting

A Study to Test How Well Different Doses of BI 3006337 Are Tolerated by People With Overweight or Obesity and With Fatty Liver Disease

Obesity | Non-alcoholic Fatty Liver Disease

United States
Arxx Therapeutics

Recruiting

A First in Human Study of AX-202 in Healthy Subjects and Patients With Psoriasis.

Healthy Volunteers | Mild to Moderate Psoriasis

United Kingdom
Yuhan Corporation

Recruiting

A Single Dose, Phase 1 Study of YH35324 in Patients With Various Allergic Diseases

Allergic Disease | Chronic Spontaneous Urticaria | Cold Urticaria | Chronic Inducible Urticaria

Korea, Republic of
PharmAbcine
Merck Sharp & Dohme LLC; Novotech (Australia) Pty Limited

Not yet recruiting

Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309 (MarkV-01)

Advanced or Metastatic Solid Tumors

Australia
NextPoint Therapeutics, Inc.

Recruiting

A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7

Metastatic Malignant Neoplasm

United States
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Study to Evaluate the Effect of a Single Oral Dose of ZX-7101A on the QTc Interval in Healthy Subjects (QTc-ZX-7101A)

Influenza, Human

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Phase Ib/II Study Confirmed Inhibition of Autophagy Synergizes Anti-tumor Effect of High Dose CDK4/6i

Inhibition of Autophagy Synergizes Anti-tumor Effect

China
Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Recruiting

The Study of Single Dose Administration of GR2002 Injection in Chinese Health Volunteers

Asthma

China
Neobiosis, LLC

Not yet recruiting

Safety, Efficacy, and Dosing of VIX001 in Patients With Neurological Symptoms of Post Acute COVID-19 Syndrome (PACS).

Cognitive Impairment | Neurological Complication | Post-Acute COVID-19 Syndrome
Sunstone Medical

Recruiting

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of up to Two Doses of Psilocybin for the Treatment of Major Depressive Disorder in Adults With Cancer

Cancer | Major Depressive Disorder

United States
Duke University
National Institutes of Health (NIH)

Not yet recruiting

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA) (MICA)

Obesity | Pediatric Obesity | Asthma in Children | Pediatric Asthma

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

A Study to Evaluate the Safety and Immunogenicity of Two Doses of DCVC H1 HA mRNA-LNP in Healthy Adults

Influenza

United States
Huabo Biopharm Co., Ltd.
M.D. Anderson Cancer Center; Dana-Farber Cancer Institute; Gabrail Cancer Center...

Not yet recruiting

A Study of HB0045 Injection in Patients With Advanced Solid Tumors

Solid Tumor, Adult

United States
Centre Francois Baclesse

Recruiting

Phase II Study of Intensity Modulated Radiotherapy in Dose Painting for Sinus Carcinomas After Endoscopic Surgery (SinocaRT)

Tumor, Solid

France
CSL Behring

Recruiting

First-In-Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Escalating Single And Multiple Doses Of CSL040 In Healthy Subjects

Complement Deficiencies

Australia
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Quantification of Fecal Calprotectin Concentration Difference Between Infants Aged Under 4 Months Old Suffering From Functional Gastrointestinal Disorders (FGID) and Infants Aged Under 4 Months Old Free From Disorders : a Transversal Case-control Monocentric Study (Cal-IBS)

Infant, Newborn, Diseases | Functional Gastrointestinal Disorders
shifeng Lou

Recruiting

A Randomized Controlled Study of High-dose Cyclophosphamide Induction Therapy in Adult Patients With HLH

Hemophagocytic Syndrome

China
HK inno.N Corporation

Recruiting

Exploratory Study to Standard Triple Therapy With Tegoprazan(by Dose) in H. Pylori Positive Patients

Helicobacter Pylori Infection

Korea, Republic of
Chulalongkorn University
HIV-NAT, Thai Red Cross - AIDS Research Centre; Chula Clinical Research Center...

Recruiting

Immunogenicity and Safety of Comvigen (Bivalent) Vaccine

Safety of a Single Dose of COMVIGEN Vaccine | Reactogenicity of a Single Dose of COMVIGEN Vaccine | Immunogenicity of a Single Dose of COMVIGEN Vaccine | Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Reactogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Immunogenicity...

Thailand
M.D. Anderson Cancer Center

Recruiting

A Study of Response Adapted Ultra Low Dose 4 Gy Radiation for Definitive Therapy of Marginal Zone Lymphoma

Lymphoma

United States
Suzhou Neologics Bioscience Co., Ltd.

Not yet recruiting

A Dose Escalation and Expansion Study of NB002 in Participants With Advanced or Metastatic Solid Tumors

Advanced Solid Tumor
Institute of Hematology & Blood Diseases Hospital...
Beijing Health Alliance Charitable Foundation

Recruiting

The Tapering Dose of Luspatercept in Patients With Lower-risk Myelodysplastic Syndromes

Lower Risk MDS Per IPSS-R

China
Tata Main Hospital

Recruiting

Dose Responsive Study of Ringer's Lactate Solution in Prevention of Post-induction Hypotension

Post Induction Hypotension

India
Pfizer

Recruiting

A Study for Multiple Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults

Healthy Participants

United States
Nanjing Ruijie Pharma Co., Ltd.

Recruiting

Ascending Single-Dose and Multiple-Dose Study to Evaluate RJ4287 in Healthy Subjects

Drug Safety

China
EyeBiotech Ltd.

Recruiting

A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD) (AMARONE)

Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (NVAMD)

United States, Argentina, Puerto Rico, United Kingdom
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

Germany, Poland, Slovakia
Boehringer Ingelheim

Recruiting

A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3

Glioma

Spain, United States, Germany, Netherlands, Austria, Switzerland
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Single and Multiple Ascending Doses Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RBD7022

Hyperlipemia

China
University of Derby
University of Exeter; University Hospitals of Derby and Burton NHS Foundation... and other collaborators

Not yet recruiting

An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID. (ERASE-LC)

COVID-19 | SARS-CoV-2 Infection

United Kingdom
Yonsei University
dotter

Recruiting

Comparative Study of Rosuvastatin/Ezetimib 20/10 mg and Atovastatin/Ezetimib 40/10 mg (TOLERANT Trial)

Coronary Artery Disease | Dyslipidemias

Korea, Republic of
Grace Lim, MD, MS
National Institute of Mental Health (NIMH)

Recruiting

Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery

Pain, Postoperative | Depression, Postpartum

United States
Alimorad Farshchian

Recruiting

Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain

Back Pain | Facet Joint Pain | Facet Joints; Degeneration

United States
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Disorders | Hb-SS Disease | Hemoglobin S | Disease Sickle Cell Anemia | Hemoglobin Beta Thalassemia Disease

United States
Erasmus Medical Center

Recruiting

TEIPP Immunotherapy in Patients With NSCLC (TEIPP)

Non Small Cell Lung Cancer

Netherlands
Chiesi Farmaceutici S.p.A.
SGS S.A.

Recruiting

Clinical Study to Evaluate the Safety, Tolerability and the Concentration of the BDP (Beclomethasone Dipropionate), Active Metabolite of BDP, FF( Formoterol Fumarate) and GB (Glycopyrronium Bromide), After Inhalation of CHF 5993 at Two Different Doses and QVAR®

Asthma

Belgium
Protherics Medicines Development Limited
Resonance Health

Recruiting

Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate

Acute Kidney Injury | Drug Toxicity

Spain, France, Italy
CHU de Quebec-Universite Laval
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapy (PRODIGY-1)

Cancer | Prostate Cancer | Metastatic Cancer | Metastatic Prostate Cancer
Boehringer Ingelheim

Recruiting

A Study in Women With Overweight or Obesity to Test Whether Different Doses of BI 456906 Influence the Amount of a Contraceptive in the Blood

Healthy

Germany
Fujian Cancer Hospital

Not yet recruiting

A Study to Evaluate Lenvatinib Plus Tislelizumab for Locally Advanced Unresectable or Metastatic Hepatocellular Carcinoma With Hepatitis B Virus Infection and Biomarker Analyses

Hepatocellular Carcinoma
The University of Texas Health Science Center,...
Skye Biologics

Not yet recruiting

Prospective Study to Determine the Safety and Effectiveness of a Connective Tissue Allograft Active Matrix (AM) vs. Standard of Care in Arthroscopic Rotator Cuff Repair

Rotator Cuff Tears

United States
GeneScience Pharmaceuticals Co., Ltd.
Afﬁliated Hospital of North Sichuan Medical College

Recruiting

Clinical Study of Multiple Dose Genakumab for Injection in Chinese Healthy Adults

Interstitial Lung Disease

China
Advanced Integrative Medical Science Institute

Not yet recruiting

Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults

Major Depression | Post Traumatic Stress Disorder

United States
Pulmongene Ltd.

Recruiting

A Multiple Ascending Doses (MAD) Study of PMG1015 in Idiopathic Pulmonary Fibrosis Subjects

IPF

China
Clinical Nutrition Research Center, Illinois Institute...
National Watermelon Promotion Board

Recruiting

Watermelon Dose Response Blood Pressure Study (WMBP)

Cardiovascular Diseases | Pre-hypertension

United States

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