Search clinical trials for: umeclidinium bromide (UMEC)

Total 822 results

Boehringer Ingelheim

Completed

Comparing the Efficacy of Tiotropium + Olodaterol (5/5 µg) Fixed Dose Combination (FDC) Over Tiotropium 5µg in Reducing Moderate to Severe Exacerbations in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease.

Pulmonary Disease, Chronic Obstructive

United States, Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, Colombia, Croatia, Czechia, Denmark, Finland, France, Germany, Greece, Guatemala, Hong Kong, Hungary, India, Ireland, Italy, Japan, Korea, Republic of, Latv... and more
GlaxoSmithKline

Completed

A Comparative Bioavailability and Adhesion Performance Study, Comparing a New Scopolamine Transdermal Delivery System Formulation to the Currently Established Reference Transdermal Delivery System in Healthy Adult Participants.

Motion Sickness

Canada
University of Florida

Terminated

A Pilot Study of Pyridostigmine in Pompe Disease

Pompe Disease

United States
Sunovion Respiratory Development Inc.

Completed

Study to Investigate the Dose Response, Safety and Efficacy of Nebulized EP-101(SUN101) in Patients With Chronic Obstructive Pulmonary Disease (COPD): GOLDEN-1 Study

Chronic Obstructive Pulmonary Disease

United States, United Kingdom
Shenzhen Hospital of Southern Medical University

Unknown

Study on Prevention and Treatment of Dry Eye in Patients Using Glaucoma Drops

Dry Eye | MGD-Meibomian Gland Dysfunction

China
GlaxoSmithKline

Completed

A 12-week Study to Evaluate the Efficacy and Safety of Umeclidinium 62.5 Microgram (mcg) Compared With Glycopyrronium 44 mcg in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Argentina, Germany, Romania, Russian Federation, Chile, Sweden, Spain, Hungary, Czechia, Norway
University of Aarhus
Aarhus University Hospital

Unknown

Effect of Pyridostigmine (Mestinon) on Muscle Strength in Myasthenia Gravis

Myasthenia Gravis

Denmark
Huashan Hospital

Unknown

Efficiency of Budesonide Combined With Formoterol and Tiotropium in the Treatment of Acute Exacerbation of ACO

Asthma-COPD Overlap
Seoul National University Hospital

Completed

Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS) (POTS)

Postural Orthostatic Tachycardia Syndrome

Korea, Republic of
Karolinska University Hospital

Completed

Methylnaltrexone as a Method to Improve Ticagrelor Uptake in Morphine Treated STEMI Patients (MOVEMENT)

STEMI | Morphine | Ticagrelor | Methylnaltrexone

Sweden
Brigham and Women's Hospital
Baim Institute for Clinical Research; Olmsted Medical Center; American Academy...

Completed

Blacks and Exacerbations on Long Acting Beta Agonists (LABA) vs. Tiotropium (BELT) (BELT)

Asthma

United States
Pneuma Respiratory, Inc

Completed

Acute Bronchodilator Effect of Inhaled Albuterol Sulfate and Ipratropium Bromide in Patients With Stable COPD

COPD

United States
Sunovion Respiratory Development Inc.

Completed

A Long-Term Safety Trial of Treatment With Nebulized SUN-101 in Patients With COPD (GOLDEN-5)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Czechia, Hungary, Russian Federation
Bausch Health Americas, Inc.
Progenics Pharmaceuticals, Inc.

Completed

Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness

Opioid-Induced Constipation

United States, Australia, Belgium, Canada, France, Germany, Italy, Mexico, Portugal, United Kingdom
Mersey Care NHS Trust
University of Central Lancashire; University of Manchester; Lancashire Care NHS... and other collaborators

Completed

Clozapine-induced Hypersalivation - Feasibility Trial (GOTHIC1)

Sialorrhea

United Kingdom
AstraZeneca
RTI Health Solutions

Completed

A Drug Utilisation Post-authorisation Study of New Users of Aclidinium Bromide (Monotherapy or in Combination) (DUS1/DUS2)

Pulmonary Disease, Chronic Obstructive

Denmark, Germany, United Kingdom
University Health Network, Toronto
Parkinson's Disease Foundation

Completed

Ipratropium Spray for Drooling Saliva in Parkinson's Disease

Parkinson's Disease

Canada
Massachusetts General Hospital

Withdrawn

Ketamine and Scopolamine Infusions for Treatment-resistant Major Depressive Disorder

Major Depressive Disorder

United States
GlaxoSmithKline

Completed

A Study to Compare the Impact of Fulticasone Furoate/Vilanterol vs. Tiotropium on Arterial Stiffness in COPD

Pulmonary Disease, Chronic Obstructive

Argentina, France, Germany, Russian Federation, Ukraine, Italy, Norway
Stiefel, a GSK Company
GlaxoSmithKline

Completed

A Study to Evaluate Clinical Effect, Pharmacokinetics , Safety, and Tolerability of Umeclidinium in Palmar Hyperhidrosis Subjects

Hyperhidrosis

United States, Canada
UMC Utrecht

Completed

SPACE Trial: Pyridostigmine vs Placebo in SMA Types 2, 3 and 4 (SPACE)

Spinal Muscular Atrophy | SMA | Kugelberg-Welander Disease

Netherlands
University of Monastir

Completed

β2-agonist Versus Ipratropium Bromide Associated With β2-agonists in Chronic Obstructive Pulmonary Disease Exacerbation

Acute Exacerbation of Chronic Obstructive Airways Disease

Tunisia
GlaxoSmithKline

Completed

24-week Trial Comparing GSK573719/GW642444 With GW642444 and With Tiotropium in Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United States, Russian Federation, Ukraine, Germany, Peru, Poland, France, Romania, Italy, Mexico
NYU Langone Health

Completed

Determination of TOF Test Threshold for Obtaining Reliable Pedicle Screw Stimulation Test During Lumbar Spine Surgery

Neuromuscular Blockade

United States
Repurposed Therapeutics, Inc.

Terminated

Pharmacokinetic and Efficacy Profile Intranasal Scopolamine Spray

Motion Sickness

United States
The Hospital for Sick Children

Completed

Bioimpedance Spectroscopy in Humans During Acute Fluid Volume Expansion With Different Crystalloid Solutions

HEALTHY

Canada
Assiut University

Completed

Oral Hyoscine Butyl Bromide Versus Diclofenac Potassium Before Office Hysteroscopy

Endoscopy

Egypt
Boehringer Ingelheim

Completed

Study to Evaluate Efficacy and Safety of Oral Doses of Hyoscine Butylbromide for the Treatment of Occasional Abdominal Pain, Cramping, and Discomfort

Colic
Boehringer Ingelheim

Completed

Dose Finding Study in COPD

Pulmonary Disease, Chronic Obstructive

Netherlands, Belgium, United States
Boehringer Ingelheim

Completed

Efficacy and Safety of Tiotropium in Patients With COPD and Concomitant Diagnosis of Asthma

Pulmonary Disease, Chronic Obstructive | Asthma

Netherlands, Germany, Belgium, France, Canada, Italy, South Africa, Denmark
Boehringer Ingelheim

Completed

Effect of Tiotropium Inhalation Capsules (Spiriva) on Exercise Tolerance in COPD Patients

Pulmonary Disease, Chronic Obstructive

Italy
National Cancer Institute (NCI)

Completed

Sulindac in Preventing Melanoma in Healthy Participants Who Are at Increased Risk of Melanoma

Precancerous Condition

United States
Sir Ganga Ram Hospital

Unknown

Evaluation of Atracurium-vecuronium Combination in Laparosocpic Surgery

Patients Undergoing Laparoscopic Surgery

India
GlaxoSmithKline

Completed

Study to Evaluate the 24-Hour Pulmonary Function Profile of Fluticasone Furoate/Vilanterol (FF/VI) Inhalation Powder 100/25mcg Once Daily Compared With Tiotropium Bromide Inhalation Powder 18mcg Once Daily in Subjects With COPD Who Have or Are At Risk for Co-morbid Cardiovascular Disease

Pulmonary Disease, Chronic Obstructive

United States, Canada, Germany, Romania, Poland, Czechia
GlaxoSmithKline

Completed

Fluticasone Propionate/Salmeterol Combination 250/50 DISKUS in the Exercise Endurance Time in Patients With Chronic Obstructive Pulmonary Disease (ESWT)

Pulmonary Disease, Chronic Obstructive

Canada, United States
GlaxoSmithKline

Completed

GSK573719 Dose Ranging Study in Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Germany, United States
GlaxoSmithKline

Completed

A Randomized, Double Blind, Placebo Controlled, Incomplete Block, Crossover, Dose Ranging Study to Evaluate the Dose Response of GSK573719 Administered Once or Twice Daily Over 7 Days in Patients With Chronic Obstructive Pulmonary Disease (COPD) (AC4115321)

Pulmonary Disease, Chronic Obstructive

United States
Huashan Hospital

Unknown

Efficiency of Twice Daily Formoterol Versus Once Daily Tiotropium in Patients With GOLD A/B COPD (FACT)

Chronic Obstructive Pulmonary Disease

China
Pearl Therapeutics, Inc.

Completed

PT001 MDI Versus Spiriva® in Patients With Moderate to Severe COPD

Chronic Obstructive Pulmonary Disease

United States
3M

Completed

Comparison of the Pharmacokinetics of Tiotropium Delivered From Test Inhaler Products With Reference

Healthy
GlaxoSmithKline

Completed

Safety Study Using GSK233705 And Tiotropium In Patients With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Germany
GlaxoSmithKline

Completed

Effect of GSK1160724 In Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Safety Study Using GSK573719 And Tiotropium In Patients With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Germany
Queen's University
GlaxoSmithKline

Completed

Effect of a New Combination Bronchodilator on Exercise in GOLD Stage II Moderate COPD

COPD

Canada
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI); Nathan Kline Institute for... and other collaborators

Completed

Safety Study of Pyridostigmine in Heart Failure (APP-HF)

Heart Failure

United States
Boehringer Ingelheim

Completed

Study to Evaluate the Efficacy and Safety of Hyoscine Butylbromide Tablets for the Treatment of Occasional or Recurrent Episodes of Gastric or Intestinal Spasm-like Pain or Discomfort

Abdominal Pain
James J. Peters Veterans Affairs Medical Center

Completed

Acetylcholinesterase Inhibition and Orthostatic Hypotension in SCI

Hypotension, Postural

United States
Assiut University

Completed

Oral Diclofenac Sodium Versus Oral Hyoscine Butyl Bromide During Intrauterine Device Insertion

Family Planning

Egypt
GlaxoSmithKline

Completed

Outcomes and Costs Associated With Initiating Maintenance Treatment With Fluticasone Propionate 250mcg/Salmeterol Xinafoate 50mcg Combination (FSC) Versus Anticholinergics Including Tiotropium (TIO) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
AstraZeneca
QuintilesIMS, Inc.

Withdrawn

To Evaluate Effectiveness of Aclidinium Bromide/Formoterol Fumarate Dihydrate in Chronic Obstructive Pulmonary Disease (ASTUTE)

Chronic Obstructive Pulmonary Disease

3

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