Search clinical trials for: first in human

Total 462068 results

Pharmacyclics LLC.

Completed

Study of Motexafin Gadolinium for the Treatment of Non-Hodgkin's Lymphoma

Lymphoma | Non-Hodgkin's Lymphoma

United States
Pharmacyclics LLC.

Completed

Study of Motexafin Gadolinium and Docetaxel for Advanced Solid Tumors

Breast Neoplasms | Lung Neoplasms | Prostatic Neoplasms | Ovarian Neoplasms

United States
Universita di Verona

Completed

A Modified Constraint-Induced Movement Therapy Program in Rehabilitation of Arm Paresis in Children With Cerebral Palsy (mCIT)

Cerebral Palsy | Hemiparesis
Assaf-Harofeh Medical Center

Unknown

Glucagon Like Peptides Receptors Expression in the Stomach of Diabetes Type 2 (GLP)

Diabetes Mellitus Type 2

Israel
Sociedad Andaluza de Trasplantes de Organos y Tejidos

Unknown

Renal Function Optimization With Mycophenolate Mofetil (MMF) Immunosuppressor Regimes (ALHAMBRA)

Kidney Diseases | Graft Rejection

Spain
Eli Lilly and Company

Completed

A Study in People With Mild Hypertension

Mild Hypertension

Sweden
Novartis

Completed

To Assess the Efficacy and Safety of Vildagliptin as Add-on Therapy to Sulfonylurea in Patients With Type 2 Diabetes Inadequately Controlled With Sulfonylurea Monotherapy

Diabetes Mellitus, Type 2

Japan
Baskent University

Completed

Clinical Factors Associated Floppy Iris

Pupil Constriction | Iris Floppiness | Iris Prolapsus From the Wound

Turkey
Innovive Pharmaceuticals

Terminated

INNO-105 in Patients With Solid Tumors

Tumors

United States
University of Turin, Italy
Dimensione Ricerca s.r.l.

Completed

Optimizing IFN Beta - 1B Dose (Optims)

Multiple Sclerosis
London North West Healthcare NHS Trust

Unknown

Do Blue-Blocking Lenses Block Blue Colour From Our Lives?

Blindness

United Kingdom
St George's, University of London

Completed

Haemodialysis Salt Reduction Study

Hypertension | Kidney Failure, Chronic

United Kingdom
King's College Hospital NHS Trust

Unknown

Do Sulphonylureas Preserve Cortical Function During Hypoglycaemia?

Type 1 Diabetes Mellitus

United Kingdom
Yonsei University

Unknown

The Effects of Exercise on Adipokine in Impaired Fasting Glucose or Impaired Glucose Tolerance Patients

Diabetes | Impaired Glucose Tolerance

Korea, Republic of
RFS Pharma, LLC

Completed

Safety, Tolerance, Pharmacokinetic and Antiviral Study of Amdoxovir in Combination With Zidovudine in Adults With HIV

HIV Infections

Argentina
Charite University, Berlin, Germany

Unknown

Selection of Shock Energy in Out-Of-Hospital Cardiac Arrest

Arrhythmia | Sudden Cardiac Death | Survival

Germany
Heidelberg University

Completed

Esomeprazole and Gastric Emptying of Beer

Gastroesophageal Reflux | Heartburn

Germany
University of Aarhus

Completed

Six Months DHEA Treatment in Female Adrenal Failure

Adrenal Insufficiency
University Magna Graecia

Completed

Treatment of Anovulatory Infertility in PCOS Patients

Polycystic Ovary Syndrome | Infertility | Anovulation

Italy
Assaf-Harofeh Medical Center

Unknown

A Comparison of Factors of Symptoms Generation and Evaluation of Role of Biofeedback in Patients With Different Types of Functional Esophageal Disorders (Functional Heartburn and Functional Chest Pain)

Chest Pain | Heartburn
University of Texas Southwestern Medical Center
American Heart Association

Unknown

Use of Beta Blockers in Elderly Trauma Patients

Cardiovascular Diseases | Multiple Trauma | Aged

United States
Tampere University

Completed

Follow-up Study of the RAI-Treated Hyperthyroid Patients

Cardiovascular Diseases | Atrial Fibrillation | Hyperthyroidism

Finland
Pfizer
Diabetes UK; Department of Health, United Kingdom

Completed

CARDS Is Designed To Show If Lowering Cholesterol With Atorvastatin In Type 2 Diabetics Without CV Disease Reduces The Risk Of CV Events (CARDS)

Angina, Unstable | Cerebrovascular Accident | Coronary Artery Bypass Graft | Revascularization | Major Coronary Event

United Kingdom
Yokohama City University Medical Center

Completed

Doxazosin Effects on ABPM in Hypertensive Patients With Diabetic Nephropathy

Diabetes Mellitus | Renal Failure | Essential Hypertension

Japan
Trans Tasman Radiation Oncology Group
Cancer Council New South Wales

Completed

SuperDEX Trial (Comparison of Two Doses of Dexamethasone for Malignant Spinal Cord Compression Treated by Radiotherapy).

Spinal Cord Compression From Neoplasm Metastasis

Australia
Chinese University of Hong Kong

Terminated

Method of Exit Site Care in Chronic Peritoneal Dialysis Patients

Chronic Peritoneal Dialysis

Hong Kong
Sunesis Pharmaceuticals

Completed

Initial Safety Assessment of SNS-595 for the Treatment of Solid Tumors.

Neoplasms

United States
Sunesis Pharmaceuticals

Completed

Safety Assessment of Weekly Intravenous Infusions of SNS-595 for the Treatment of Solid Tumors

Neoplasms

United States
University of Aarhus

Completed

Simvastatin Reduces Circulating Osteoprotegerin Levels in Patients With Type 2 Diabetes

Type 2 Diabetes
University of Giessen
Novartis; Hoffmann-La Roche; Astellas Pharma Inc; Heidelberg University; Fresenius... and other collaborators

Completed

Th1, Th2 and Monokine Responses as Risk Factors of Renal Transplant Rejection

Renal Failure, Chronic

Germany
University of Giessen
Hoffmann-La Roche; Astellas Pharma Inc; Heidelberg University; Aventis Pharmaceuticals

Completed

Immunoregulatory Effects of Immunoglobulin Induction Therapy in Renal Transplant Recipients

Renal Transplantation | Renal Failure, Chronic

Germany
Novartis

Completed

A Study To Compare the Effect of Vildagliptin Compared to Placebo in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Japan
Pamela Youde Nethersole Eastern Hospital

Unknown

Compare Efficacy of Gastric Acid Suppression by Oral and Intravenous Administration of Esomeprazole in Patients With Peptic Ulcer (NPH)

Peptic Ulcer

China
Yokohama City University Medical Center

Completed

Autonomic Imbalance and 24-h Blood Pressure Change in Patients With Chronic Renal Disease

Diabetes Mellitus | Renal Failure | Essential Hypertension | Chronic Nephropathy

Japan
Yokohama City University Medical Center

Completed

Effects of Atorvastatin Versus Probucol on Small Dense LDL

Chronic Nephropathy

Japan
Heidelberg University

Unknown

Weight Loss in Obese Children and Adolescents and Its Effect on Improvement of Destructive Changes in Blood Vessels

Obesity

Germany
University of Minnesota
National Institute of Nursing Research (NINR)

Completed

An Intervention to Improve End of Life Decision Making Among Homeless Persons

Advance Care Planning | End of Life Decision Making

United States
Manhattan Eye, Ear & Throat Hospital
Alcon Research

Terminated

Treatment of Diabetic Retinopathy With Open-Label Anecortave Acetate Sterile Suspension (15 mg)

Diabetic Retinopathy

United States
Heinrich-Heine University, Duesseldorf

Completed

Sunscreen RV 2457C in Photoinduced CLE

Skin Lesion | Cutaneous Lupus Erythematosus | Experimental Photoinduction | Protective Sunscreen

Germany
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Sirolimus/Prograf vs Sirolimus/CsA in High-Risk Renal Transplant Recipients

Renal Allograft Recipients
University of Roma La Sapienza

Unknown

The Efficacy of Color-Doppler Ultrasonography to Assess the Renal Blood Flow With the Estimation of GFR

Hypertension | Renal Failure

Italy
University of California, Los Angeles
Robert Wood Johnson Foundation

Completed

Educational Technology to Enhance Diabetes Care - Retention Study

Diabetes Mellitus

United States
HaEmek Medical Center, Israel

Unknown

The Effect of Licorice Root Extract and Pomegranate Juice on Atherosclerotic Parameters in Diabetic Patients

Diabetes Mellitus | Atherosclerosis

Israel
Pharmacyclics LLC.

Terminated

Motexafin Gadolinium With Chemotherapy and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer

Head and Neck Cancer | Oropharynx Cancer | Larynx Cancer | Hypopharynx Cancer

United States
National Health Research Institutes, Taiwan

Unknown

Molecular Genetic Study of Avascular Necrosis of the Femoral Head

Osteonecrosis

Taiwan
HaEmek Medical Center, Israel

Unknown

The Effect of a Natural Polyphenolic Extract From Pomegrnate (POMX) on the Development of Atherosclerosis in Diabetic Patients (POMX)

Atherosclerosis

Israel
Seattle Cancer Treatment and Wellness Center

Unknown

Weekly Dosing of an Integrative Chemotherapy Combination to Treat Advanced Pancreatic Cancer

Stage III Pancreatic Cancer | Stage IVA Pancreatic Cancer | Stage IVB Pancreatic Cancer | Adenocarincoma of Pancreas

United States
University of Toronto
Almond Board of California; Unilever R&D; Natural Sciences and Engineering Research... and other collaborators

Completed

The Effect of Strawberries in a Cholesterol-Lowering Dietary Portfolio

Cardiovascular Diseases | Hypercholesterolemia | Hyperlipidemia

Canada
Goldschleger Eye Institute

Completed

Titanium-Sapphire Laser Trabeculoplasty in Glaucoma: A Randomized Study Comparing Titanium-Sapphire With Argon Laser Trabeculoplasty in Open-Angle Glaucoma Patients

Glaucoma, Open-Angle

Israel
Instituto Nacional de Perinatologia Isidro Espinosa...
University of Pennsylvania; Bill and Melinda Gates Foundation

Terminated

L-Arginine and Antioxidant Vitamins During Pregnancy to Reduce Preeclampsia (L-Arg)

Pre-Eclampsia

United States, Mexico

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