Clinical Trials Sponsored by Addenbrookes Hospital, Cambridge

Total 384 results

GlaxoSmithKline
Clinical Unit at Cambridge (Addenbrooks)

Completed

A Safety and Tolerability Study of GSK2982772, in Single (in Both Fed and Fasted States) and Repeat Oral Doses in Healthy Male Subjects

Inflammatory Bowel Diseases

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge; University of Dublin, Trinity College; The Dunhill Medical... and other collaborators

Terminated

Feasibility of Additional Physiotherapy for Patients Aged 75 and Older (Stand-UP)

Exercise | Older Adults | Hospitalisation

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Addenbrookes Charitable Trust; PKD Charity; British Renal Society & British Kidney...

Completed

High Water Intake in Polycystic Kidney Disease (DRINK)

Autosomal Dominant Polycystic Kidney Disease

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Gates Cambridge

Completed

Computerised Therapy in Chronic Stroke (CATChES)

Chronic Aphasia

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Not yet recruiting

Continuous Ambulatory Cardiac Monitoring for Recurrent Atrial Fibrillation After Sepsis (CAMS-AF)

Infections | Sepsis | Atrial Fibrillation | Cardiac Arrhythmia

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Recruiting

CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy

Multiple Sclerosis

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Not yet recruiting

Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO Study (PROSPERO)

Gastric Cancer | Esophageal Cancer | Barrett Esophagus | Barretts Esophagus With Dysplasia | Gastric Intestinal Metaplasia | Gastric Atrophy | Duodenal Adenoma | Esophageal Dysplasia | Duodenum Cancer | Gastric Polyp
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Not yet recruiting

Pharmacological Management of Seizures Post Traumatic Brain Injury (MAST)

Traumatic Brain Injury | Post Traumatic Seizures
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Recruiting

Influence of Age, Weight and Ethnic Background on Blood Pressure (AWE)

Cardiovascular Diseases | Vascular Diseases | Hypertension

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Closing the Loop in Adults With Type 1 Diabetes (CLEAR)

Type 1 Diabetes

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Completed

INvestigating the Lowest Threshold of Vascular bENefits From LDL Lowering With a PCSK9 InhibiTor in healthY Volunteers

Cardiovascular Diseases | Atherosclerosis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Withdrawn

PROphylaxis for paTiEnts at Risk of COVID-19 infecTion (PROTECT)

COVID-19
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Unknown

Prevalence of Musculoskeletal Symptoms in the Cambridge NIHR BioResource

Musculoskeletal Diseases | Musculoskeletal Injury
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Unknown

CETO First in Human Trial (CETO)

Primary Aldosteronism

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Completed

The Feasibility of Drug Delivery to Infants During Breastfeeding (FEDD)

Breast Feeding | Milk, Human | Infant, Newborn | Medication Systems

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Cambridge Theranostics Ltd

Completed

TomVasc - Vascular Effects of Tomato Extract (TomVasc)

Stroke | Transient Ischemic Attack | Peripheral Vascular Disease | Ischemic Heart Disease

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Closing the Loop for 36 Hours in Adolescents With Type 1 Diabetes: Evaluation of Reduced Meal Bolusing

Type 1 Diabetes

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Automated Overnight Closed-loop Glucose Control in Young People With Type 1 Diabetes (APCam05)

Type 1 Diabetes

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge; Cambridge Stem Cell Institute, Cambridge; Anne McLarent... and other collaborators

Unknown

Regenerative Cellular Therapies, Physiology, Pathology and Developmental Biology (RCT)

Diabetes Mellitus | Graft Rejection | Transplantation

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Terminated

Molecular Investigation of Genetic Factors in CArDiovascular Diseases Using an BIOresource of Healthy Volunteers (CADBIO)

Cardiovascular Diseases

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Active, not recruiting

Investigating the Lowest Threshold of Vascular Benefits From LDL Cholesterol Lowering in Patients With Stable CV Disease (INTENSITY-HIGH)

Cardiovascular Diseases | Atherosclerosis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Completed

CamPROBE: Developing a Safer and Simple Device for Local Anaesthetic Transperineal Prostate Biopsies (CamPROBE)

Prostate Cancer

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Completed

Exploring the Use of ECochG Testing During Electrode Insertion in Cochlear Implant Surgery

Cochlear Implants | Hearing Preservation

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Closing the Loop 24/7 in Adolescents With Type 1 Diabetes (DAN04)

Glucose Metabolism Disorders | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Cambridge Temperature Concepts

Completed

Comparison of DuoFertility, LadyComp/BabyComp and Clearblue Monitors

Infertility

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Closing the Loop in Youth With Type 1 Diabetes in the Home Setting

Type 1 Diabetes

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Closing the Loop in Adolescents During Non-compliance Behaviours

Type 1 Diabetes

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Closing the Loop in Adults With Type 1 Diabetes - Alcohol Consumption (ANGELA02)

Type 1 Diabetes

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Unknown

Early Metabolic Changes With Thiazide or Beta Blocker Therapy for Essential Hypertension

Essential Hypertension

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Recruiting

Speeded Anomia Treatment in Chronic Post-stroke Aphasia

Aphasia

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Recruiting

Molecular Investigation of GENetic Factors in Cardiovascular and Immune-related Traits and Diseases Using a BIOresource of Healthy Volunteers (GENBIO) (GENBIO)

Cardiovascular Diseases

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Not yet recruiting

A Study of Wrist Worn Accelerometers in End-Stage Renal Disease (W-WARD)

Chronic Kidney Diseases | Frailty | End Stage Renal Disease on Dialysis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Recruiting

Neonatal Wireless Monitoring System for Intensive Care

Preterm Infant | Low; Birthweight, Extremely (999 Grams or Less) | Infant, Newborn

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Completed

Low Dose Interleukin-2 in Patients With Stable Ischaemic Heart Disease and Acute Coronary Syndromes (LILACS)

Ischemic Heart Disease

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Completed

Natural Language Processing (NLP) Analysis of Free Text Notes to Investigate Coronavirus (COVID-19)

COVID-19

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Unknown

TBI Multimodal Monitoring Study (monTBI)

Traumatic Brain INjury | Microdialysis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Suspended

Capture of Prostatic Trans-rectal Ultrasound Scans for Research (CAPTURE)

Prostate Cancer | Prostate Neoplasm

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Terminated

HYPAZ: Hypertension Induced by Pazopanib (HYPAZ)

Melanoma | Soft Tissue Sarcoma | Renal Cell Carcinoma | Cervical Cancer | Breast Cancer | Small Cell Lung Cancer | Glioblastoma | Pancreatic Cancer | Ovarian Cancer | Non-small Cell Lung Cancer | Gastrointestinal Cancer

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Automated Closed-loop in Children and Adolescents With Type 1 Diabetes (APCam09)

Glucose Metabolism Disorders | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Evaluation of Gut Absorption Rate of Glucose After a Large Evening Meal in Type 1 Diabetes

Type 1 Diabetes
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Achieving Normal Glucose In Hospital Settings (Angie01)

Dysglycaemia

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Closing the Loop for 36 Hours in Adolescents With Type 1 Diabetes

Type 1 Diabetes

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge; Cancer Research UK Cambridge Institute

Completed

EVIS - Ex-vivo Assessment of T-lymphocyte Homing in Primary Pancreatic Cancer (EVIS)

Pancreatic Cancer

United Kingdom
University of Cambridge
University Hospital Inselspital, Berne; Cambridge University Hospitals NHS...

Completed

Closed-loop Insulin Delivery in the General Ward (ANGIE02)

Diabetes Mellitus

United Kingdom, Switzerland
Ruijin Hospital
University of Cambridge

Unknown

The Efficacy and Mechanism of DBS in VIC and NAcc for Refractory OCD

Obsessive-Compulsive Disorder | Deep Brain Stimulation

China
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; University of Cambridge

Terminated

A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems (PRIME)

Drug-Related Side Effects and Adverse Reactions | Cardiovascular System Disease

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline; National Institute for Health Research, United Kingdom; Kidney... and other collaborators

Recruiting

PROphylaxis for paTiEnts at Risk of COVID-19 infecTion -V (PROTECT-V)

Covid19

United Kingdom
Sophie McKenny
University of Cambridge

Enrolling by invitation

Objective Measures of Cochlear Implant Electrode Position and Function

Cochlear Implants

United Kingdom
Joanne Outtrim
University of Cambridge

Unknown

Understanding Pre-operative Activity Levels in Elderly Patients

Physical Activity | Aging | Surgery

United Kingdom
Adel Helmy
Cambridge University Hospitals NHS Foundation Trust

Unknown

IL-1ra Dose-range Study for Moderate-to-severe TBI Patients (IL1ra)

Traumatic Brain INjury

United Kingdom

Clinical Trials Sponsored by Addenbrookes Hospital, Cambridge

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