Clinical Trials Sponsored by Advanced Cancer Therapeutics

Total 502 results

Advanced Cancer Therapeutics

Unknown

Phase 1 Safety Study of ACT-PFK-158, 2HCl in Patients With Advanced Solid Malignancies

Cancer

United States
Cardium Therapeutics
Advanced Biosciences Research

Terminated

Efficacy and Safety of Ad5FGF-4 for Myocardial Ischemia in Patients With Stable Angina Due to Coronary Artery Disease (ASPIRE)

Angina, Stable

Russian Federation
Cancer Advances Inc.

Completed

Open-label, Dose-finding Study to Determine Antibody Response to G17DT Treatment in Patients With Gastric Cancer. (GC3)

Gastric Cancer
Cancer Advances Inc.

Terminated

A Study of the Safety and Tolerance of Three Doses of G17DT in Metastatic Colorectal Cancer (CC1C)

Colorectal Cancer
Cancer Advances Inc.

Completed

Safety and Efficacy of G17DT Immunogen in the Treatment of Gastric and Gastroesophageal Cancer

Stomach Neoplasms | Esophageal Neoplasms
Cancer Advances Inc.

Completed

An Open, Single-center Study to Determine the Antibody Repsonse to Gastrimmune and Its Safety and Tolerability in Patients With Advanced Pancreatic Carcinoma (PC1)

Pancreatic Cancer
Cancer Advances Inc.

Completed

Single Centre Study to Determine the Antibody Response to G17DT in Patients With Advanced Pancreatic Cancer.

Pancreatic Cancer | Jaundice
Cancer Advances Inc.

Completed

Two Center Study to Determine Effect of G17DT on Plasma Gastrin Levels in Patients With Colorectal Cancer. (CC4)

Colorectal Cancer

United Kingdom
Cancer Advances Inc.

Completed

Effect of G17DT in Patients With Stage II/III Colorectal Cancer (CC5)

Colorectal Cancer
Cancer Advances Inc.

Completed

Study to Assess Safety and Tolerability of G17DT in Patients With Colorectal Adenocarcinoma. (CC1A&B)

Colorectal Cancer

United Kingdom
Cancer Advances Inc.

Completed

Phase II Study to Evaluate G17DT in Combination With Irinotecan in Patients With Colorectal Carcinoma (CC6)

Colorectal Cancer
Cancer Advances Inc.

Completed

Safety and Efficacy of G17DT Immunogen Combined With Gemcitabine vs. Gemcitabine in the Treatment of Advanced Pancreatic Carcinoma

Pancreatic Cancer
Cancer Advances Inc.

Completed

An Open Label Study to Evaluate G17DT Compared to Gemcitabine

Pancreatic Cancer
Cancer Advances Inc.

Completed

Study to Determine the Antibody Response to 500µg G17DT in Treatment of Patients With Gastric Cancer (GC5)

Gastric Cancer

United Kingdom
Cancer Advances Inc.

Completed

Sequential Trial of G17DT for the Treatment of Advanced Pancreatic Cancer (PC6)

Pancreatic Cancer
Therapeutic Advances in Childhood Leukemia Consortium

Completed

Epigenetic Reprogramming in Relapse/Refractory AML

Acute Myelogenous Leukemia

United States, Canada, Australia
Therapeutic Advances in Childhood Leukemia Consortium

Not yet recruiting

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Neurofibromatosis 1 | JMML | Leukemia, Juvenile Myelomonocytic | JCML | CBL Syndrome
Therapeutic Advances in Childhood Leukemia Consortium

Completed

Bortezomib With Chemotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia (ALL)

Acute Lymphoblastic Leukemia

United States, Australia, Canada, Brazil
Therapeutic Advances in Childhood Leukemia Consortium

Terminated

Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia

Relapsed Acute Lymphoblastic Leukemia | Relapsed Acute Myelogenous Leukemia

United States
Therapeutic Advances in Childhood Leukemia Consortium

Recruiting

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Lymphoma, B-Cell | Hodgkin Lymphoma | Lymphoblastic Lymphoma | Lymphoma, T-Cell | AML | Hematologic Malignancy | MDS | Acute Undifferentiated Leukemia | ALL | Mixed Phenotype Acute Leukemia | BPDCN

United States, Australia
Therapeutic Advances in Childhood Leukemia Consortium

Terminated

A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL

Acute Lymphoblastic Leukemia | Precursor B-Cell Lymphoblastic Leukemia | Precursor T-Cell Lymphoblastic Leukemia

United States, Australia
Therapeutic Advances in Childhood Leukemia Consortium

Terminated

Erwinase for Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) (IND 104224)

Relapsed Acute Lymphoblastic Leukemia | Allergy to PEG e.Coli Asparaginase | Allergy to Native e.Coli Asparaginase

United States
Therapeutic Advances in Childhood Leukemia Consortium
Gateway for Cancer Research

Completed

A Phase I Study of 5-Azacytidine in Combination With Chemotherapy for Children With Relapsed or Refractory ALL or AML

Lymphoblastic Leukemia, Acute, Childhood | Myelogenous Leukemia, Acute, Childhood

United States, Canada, Australia
Melinta Therapeutics, Inc.
Biomedical Advanced Research and Development Authority

Terminated

Safety and Efficacy of Solithromycin in Adolescents and Children With Community-Acquired Bacterial Pneumonia

Community-acquired Bacterial Pneumonia

Spain, United States, Philippines, Hungary, United Kingdom, Bulgaria
Therapeutic Advances in Childhood Leukemia Consortium
Pfizer

Completed

A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma

Lymphoblastic Lymphoma | Peripheral T-cell Lymphoma | Lymphoblastic Leukemia, Acute, Childhood

United States, Canada, Australia
Therapeutic Advances in Childhood Leukemia Consortium
Abbott

Terminated

ABT-751 With Chemotherapy for Relapsed Pediatric ALL

Acute Lymphoblastic Leukemia | Relapsed Pediatric ALL | Recurrent Pediatric ALL | Refractory Pediatric ALL

United States
Therapeutic Advances in Childhood Leukemia Consortium
Novartis

Completed

A Study Of Panobinostat In Children With Refractory Hematologic Malignancies

Non-Hodgkin's Lymphoma | Lymphoblastic Leukemia, Acute, Childhood | Hodgkin's Disease | Myelogenous Leukemia, Acute, Childhood

United States
Abvance Therapeutics
T1D Exchange, United States

Completed

A Trial to Investigate Hyperglycemic and Hypoglycemic Excursions in Subjects With Type 1 Diabetes

Type 1 Diabetes Mellitus With Hypoglycemia

United States
Advanced Center for Eyecare Global

Not yet recruiting

Impact of Free Reading Glasses on Work and Visual Function Following Cataract Surgery in Honduras (POWER)

Cataract Surgery
Therapeutic Advances in Childhood Leukemia Consortium
GlaxoSmithKline; Novartis

Terminated

Trial of Nelarabine, Etoposide and Cyclophosphamide in Relapsed T-cell ALL and T-cell LL

Relapsed T-Cell Acute Lymphoblastic Leukemia | Relapsed T-Cell Lymphoblastic Lymphoma

United States, France, Canada, Australia, Austria, Italy, Netherlands
Etan Orgel
Therapeutic Advances in Childhood Leukemia Consortium

Recruiting

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL (IDEAL2)

Obesity | B-cell Acute Lymphoblastic Leukemia

United States
Advanced Center for Specialty Care
Takeda

Unknown

Dexlansoprazole to Treat Laryngopharyngeal Reflux and Lingual Tonsil Hypertrophy

Laryngopharyngeal Reflux | Hypertrophy of Lingual Tonsil

United States
Therapeutic Advances in Childhood Leukemia Consortium
Bristol-Myers Squibb

Active, not recruiting

Nivolumab in Combination With 5-azacytidine in Childhood Relapsed/Refractory AML

AML, Childhood

United States
Rush University Medical Center
Advanced Rx

Active, not recruiting

Potential for Cortisol Suppression With the Use of High Volume Nasal Mometasone Irrigations in Varying Dosages.

Chronic Rhinosinusitis (Diagnosis)

United States
Maastricht University Medical Center
Advanced Bionics

Unknown

Assessment of the AB HiFocusTM Mid Scala Electrode Movement Using Cone Beam Imaging Following Cochlea Implantation (ABMS1)

Cochlear Implantation | Cone-Beam Computed Tomography

Netherlands
Therapeutic Advances in Childhood Leukemia Consortium
Spectrum Pharmaceuticals, Inc

Recruiting

Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults With Relapsed ALL

Lymphoblastic Leukemia, Acute, Childhood | ALL, Childhood | Lymphoblastic Leukemia, Acute

United States, Australia, Canada
Therapeutic Advances in Childhood Leukemia Consortium
Enzon Pharmaceuticals, Inc.

Terminated

EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)

Lymphoblastic Leukemia, Acute, Childhood | Leukemia, Lymphoblastic, Acute | Lymphoblastic Leukemia, Acute | Leukemia, Lymphoblastic, Acute, T Cell

United States, Australia
Therapeutic Advances in Childhood Leukemia Consortium
Ambit Biosciences Corporation

Completed

AC220 for Children With Relapsed/Refractory ALL or AML

Lymphoblastic Leukemia, Acute, Childhood | Myelogenous Leukemia, Acute, Childhood

United States
Fox Chase Cancer Center
WindMIL Therapeutics

Withdrawn

Feasibility Study on Expandion of MILs From NSCLC and SCLC Patients and Infusion With Pembrolizumab

NSCLC | SCLC
M.D. Anderson Cancer Center
Alaunos Therapeutics

Completed

Phase I Trial of ZIO-101 in Patients With Solid Tumors

Solid Tumors

United States
Cancer Advances Inc.
PPD; ChapelPharma Ltd

Completed

Study to Assess Tolerability and Safety and Antibody Response to G17DT in Gastric Cancer Patients

Gastric Cancer
Luminary Therapeutics
Case Comprehensive Cancer Center

Recruiting

Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin Lymphoma, B-Cell

United States
Alaunos Therapeutics
M.D. Anderson Cancer Center

Suspended

HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors

Ovarian Cancer | Cholangiocarcinoma | Endometrial Cancer | Non-small Cell Lung Cancer | Pancreas Cancer | Colo-rectal Cancer

United States
Fred Hutchinson Cancer Center
ADC Therapeutics

Withdrawn

Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Recurrent High... and other conditions

United States
M.D. Anderson Cancer Center
Direct Therapeutics

Completed

Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas

Glioma | Brain Neoplasms

United States
M.D. Anderson Cancer Center
BreakThrough Therapeutics

Completed

Synthetic Vaccine in Patients With Chronic Myeloid Leukemia and Minimal Residual Disease

Chronic Myeloid Leukemia | Minimal Residual Disease

United States
M.D. Anderson Cancer Center
vTv Therapeutics

Withdrawn

TTP607 in Refractory Solid Malignancies

Lymphoma | Advanced Cancers
Introgen Therapeutics
M.D. Anderson Cancer Center

Unknown

Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit Melanoma

Neoplasm Metastasis | Malignant Melanoma

United States
M.D. Anderson Cancer Center
Elevar Therapeutics

Not yet recruiting

A Phase II Study of Rivoceranib for Patients With Recurrent or Metastatic Olfactory Neuroblastoma

Metastatic Olfactory Neuroblastoma | Recurrent Olfactory Neuroblastoma

United States
M.D. Anderson Cancer Center
Mirati Therapeutics

Recruiting

Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer

Colorectal Cancer | Colon Cancer

United States

Clinical Trials Sponsored by Advanced Cancer Therapeutics

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