Clinical Trials Sponsored by Aerie Pharmaceuticals

Total 19687 results

Inovio Pharmaceuticals

Completed

Phase I of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + Electroporation for CIN 2 or 3

Papillomavirus Infections

United States, Puerto Rico
Ferring Pharmaceuticals

Completed

A Clinical Study to Evaluate the Pharmacokinetics of Testosterone Gel Using an Applicator

Hypogonadal Males

United States
Ferring Pharmaceuticals

Completed

Efficacy, Pharmacokinetics and Safety of Testosterone

Testicular Hypogonadism

United States
Edimer Pharmaceuticals

Completed

Natural History and Outcomes in X-Linked Hypohidrotic Ectodermal Dysplasia (ECP-015)

X-Linked Hypohidrotic Ectodermal Dysplasia

United States, United Kingdom, France, Germany, Italy
MinaPharm Pharmaceuticals

Unknown

Gonapure® in Multifollicular Stimulation in Egyptian Women Undergoing IVF/ICSI (GIVF)

Female Infertility

Egypt
Primus Pharmaceuticals

Completed

Diosmiplex (Vasculera®) in Primary and Secondary Raynaud's Phenomenon

Raynaud's Disease

United States
Deltanoid Pharmaceuticals

Completed

Safety Study of an Oral Vitamin D Analog in Postmenopausal Women

Postmenopausal Osteoporosis, Multiple Sites
Ferring Pharmaceuticals

Completed

A Phase III Study With FE 999169 Versus Niflec for Colon Cleansing

Colon Cleansing in Preparation for Colonoscopy

Japan
Peregrine Pharmaceuticals

Withdrawn

Taxane Therapy With or Without Bavituximab for the Treatment of HER2-Negative Metastatic Breast Cancer

Metastatic Breast Cancer

United States
Sunesis Pharmaceuticals

Completed

Study of Voreloxin (Vosaroxin) in Older Patients With Untreated Acute Myeloid Leukemia

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Acute Disease | Nonlymphocytic Leukemia

United States
Prolong Pharmaceuticals

Completed

A Phase 1 Safety Study of SANGUINATE™ In Patients With Acute Severe Anemia.

Acute Anemia

United States
Ferring Pharmaceuticals

Completed

Effect of Oxytocin and Vasopressin Antagonists on Uterine Contractions (OVANCON)

In Vitro Fertilisation (IVF) Treatment

Belgium, Czechia, Spain
Catabasis Pharmaceuticals

Completed

A Study to Assess the Safety and Efficacy of CAT-2054 in Combination With Atorvastatin in Patients With Hypercholesterolemia

Hypercholesterolemia

United States
Alexion Pharmaceuticals

Terminated

Screening for Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

United States
Dauntless Pharmaceuticals

Completed

Study of Intranasal Octreotide (DP1038) in Healthy Adult Volunteers

Healthy Volunteer Study

United States
Alexion Pharmaceuticals

Completed

Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan

Hypophosphatasia
Regeneron Pharmaceuticals

Completed

Study of the Safety and Effectiveness of Rilonacept for the Prevention of Gout Flares

Gout

United States
Peregrine Pharmaceuticals

Completed

Trial of Gemcitabine With or Without Bavituximab in Patients With Previously Untreated Stage IV Pancreatic Cancer

Metastatic Pancreatic Cancer

United States, Ukraine
Quark Pharmaceuticals

Completed

Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG)

Glaucoma, Angle-closure, Primary, Acute

Singapore, United States, Vietnam
Jazz Pharmaceuticals

Terminated

A Dose Confirmation and Pharmacokinetic Study of Pegcrisantaspase Administered as Intravenous (IV) Infusion in Children and Young Adults With Acute Lymphoblastic Leukemia (ALL) /Lymphoblastic Lymphoma (LBL). Following Hypersensitivity to Pegaspargase (Oncaspar)

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma

United States
Cornerstone Pharmaceuticals

Terminated

A Phase I/II Open-Label Dose-Escalation Clinical Trial of CPI-613 in Combination With Gemcitabine in Cancer Patients

Cancer | Pancreatic Cancer | Pancreatic Carcinoma

United States
Avanir Pharmaceuticals

Completed

Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA) (PRISM II)

Stroke | Dementia | Traumatic Brain Injury (TBI) | Pseudobulbar Affect (PBA)

United States
Concert Pharmaceuticals

Completed

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CTP-543 in Healthy Subjects

Healthy

Australia
Peregrine Pharmaceuticals

Withdrawn

A Study of Neoadjuvant Paclitaxel in Combination With Bavituximab in Early- Stage Triple- Negative Breast Cancer

Breast Cancer | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Triple-Negative Breast Cancer | Triple-Negative Breast Neoplasm | ER-Negative PR-Negative HER2-Negative Breast Neoplasms | ER-Negative PR-Negative HER2-Negative Breast Cancer
Alexion Pharmaceuticals

Terminated

aHUS Observational Long Term Follow-Up (LTFU)

Atypical Hemolytic Uremic Syndrome

France, Canada, United States, Belgium, Italy, United Kingdom, Netherlands, Australia, Austria, Germany, Sweden, Switzerland
Alexion Pharmaceuticals

Completed

Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass

Coronary Artery Bypass Graft | Cardio-pulmonary Bypass

United States, Canada
Ferring Pharmaceuticals

Completed

A Study of Degarelix in Patients With Prostate Cancer

Prostate Cancer

United States
ASLAN Pharmaceuticals

Completed

Phase 1, Randomised Double Blinded Placebo Controlled Study of ASLAN003

Healthy Volunteers

Singapore
Yali Pharmaceuticals

Completed

A Phase I/II to Assess Safety, Tolerability and Efficacy of DL-lactic Acid Syrup in Children With Recurrent Tonsillitis

Recurrent Tonsillitis in Children

Israel
Rigel Pharmaceuticals

Completed

To Assess the Safety and Efficacy of R932348 Ophthalmic Solutions in Patients With Keratoconjunctivitis Sicca (DROPS)

Keratoconjunctivitis Sicca

United States
Rigel Pharmaceuticals

Completed

A Safety and Efficacy Study of Inhaled R940343 in Patients With Mild to Moderate Asthma (SITAR)

Asthma

United States, Canada
Tarix Pharmaceuticals

Terminated

Phase I Study Evaluating TXA127 in Low/Intermediate-1 Risk Myelodysplastic Syndrome and Thrombocytopenia

Myelodysplastic Syndrome (MDS)

United States
Karos Pharmaceuticals

Completed

Single and Multiple Ascending Doses Clinical Pharmacology Study With KAR5585

Pulmonary Arterial Hypertension

United States
Merrimack Pharmaceuticals

Completed

A Study of MM-121 Combination Therapy in Patients With Advanced Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

Spain, Taiwan, United States, Canada, Korea, Republic of, Germany
Jazz Pharmaceuticals

Withdrawn

Phase 3, 28-week, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of Nabiximols as an add-on Therapy in Subjects With Spasticity Due to Multiple Sclerosis.

Multiple Sclerosis | Spasticity
Progen Pharmaceuticals

Completed

Study of CGC-11047 When Used in Individual Combinations With 1) Gemcitabine or 2) Docetaxel or 3) Bevacizumab or 4) Erlotinib or 5) Cisplatin or 6) 5-Flurouracil or 7) Sunitinib in Patients With Advanced Solid Tumors or Lymphoma

Cancer

United States
Avanir Pharmaceuticals

Completed

Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS

Amyotrophic Lateral Sclerosis

United States
Alexion Pharmaceuticals

Completed

Evaluation of Blood Brain Barrier Integrity and Structural Abnormalities in MPS IIIB Patients Using Multimodal Magnetic Resonance Imaging

MPS IIIB (Sanfilippo B Syndrome)

United Kingdom
Alexion Pharmaceuticals

No longer available

An Expanded Access Protocol for Sebelipase Alfa for Patients With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency
TetraLogic Pharmaceuticals

Completed

Dose Escalation, Combination Chemotherapy Safety Study of Birinapant (TL32711), in Subjects With Advanced or Metastatic Solid Tumors

Cancer

United States
Regeneron Pharmaceuticals

Completed

Study to Assess the Safety and Tolerability of Single Doses of REGN1500

Hypertriglyceridemia

United States
Regeneron Pharmaceuticals

Completed

Study of Fasinumab (REGN475) in Healthy Japanese and Caucasian Subjects

Healthy Volunteers

United States
Regeneron Pharmaceuticals

Terminated

Study of REGN1193 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Merrimack Pharmaceuticals

Completed

Trial of Exemestane +/- MM-121 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive and/or Progesterone Receptor Positive Her2 Negative Breast Cancer

Her2 Negative Breast Cancer Patients

United States, Spain, Canada, Germany, Russian Federation
Concert Pharmaceuticals

Completed

Food Effect Study of CTP-656 in Healthy Male Volunteers

Healthy

Australia
SymBio Pharmaceuticals

Completed

Efficacy and Safety Study of SyB L-0501 in Combination With Rituximab in Patients With Untreated, Low-grade B Cell Non-Hodgkin's Lymphoma and Mantle Cell Lymphoma

Low-grade B Cell Non-Hodgkin's Lymphoma | Mantle Cell Lymphoma Where Hematopoietic Stem Cell Transplantation is Not Indicated

Japan
Cumberland Pharmaceuticals

Completed

Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery

Pain

United States
Lexicon Pharmaceuticals

Unknown

Oral Contraceptive DDI Study

Healthy

United States
BioCryst Pharmaceuticals

Terminated

Open-label, Long-term Safety Study of Avoralstat in Subjects With Hereditary Angioedema (OPuS-4)

Hereditary Angioedema | HAE

France, Belgium
TetraLogic Pharmaceuticals

Completed

Study of Birinapant in Combination With Conatumumab in Subjects With Relapsed Ovarian Cancer

Relapsed Epithelial Ovarian Cancer | Relapsed Primary Peritoneal Cancer | Relapsed Fallopian Tube Cancer

United States

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