Clinical Trials Sponsored by Akros Bioscience

Total 1948 results

Akros Pharma Inc.

Withdrawn

Study to Evaluate Efficacy and Safety of JTT-251 in Participants With Pulmonary Arterial Hypertension (RELIEF-PAH)

Pulmonary Arterial Hypertension
Akros Pharma Inc.

Completed

Mass Balance Study of JTZ-951 in Subjects With End-stage Renal Disease on Hemodialysis

Anemia of Chronic Kidney Disease

United States
Akros Pharma Inc.

Completed

Study to Evaluate Effect of Lapatinib on Pharmacokinetics of JTZ-951 in Subjects With End-stage Renal Disease

Anemia of Chronic Kidney Disease

United States
Akros Pharma Inc.

Completed

Effect of Hemodialysis on the PK of JTZ-951 in Subjects With End-stage Renal Disease

Anemia in Chronic Kidney Disease

United States
Akros Pharma Inc.

Terminated

Efficacy and Safety Study of JTT-654 in Type 2 Diabetic Patients

Type II Diabetes Mellitus

United States
Akros Pharma Inc.

Completed

Study to Evaluate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of JTT-662 in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States
Akros Pharma Inc.

Completed

Study of Safety, Tolerability and Pharmacokinetics of Single Oral JTT-251 Doses in Healthy and Type 2 Diabetic Subjects

Diabetes Mellitus

United States
Akros Pharma Inc.

Completed

Efficacy and Safety Study of JTT-302 in Subjects With Low HDL-C Levels

Dyslipidemia

United States
Akros Pharma Inc.

Completed

Safety and Efficacy Study of JTT-130 in Obese Type 2 Diabetic Patients

Type II Diabetes Mellitus

United States, Russian Federation, Czech Republic, Hungary, Netherlands
Akros Pharma Inc.

Completed

Safety, Tolerability and Pharmacokinetics Study Assessing Ascending Single Oral JTK-853 Doses in Healthy Subjects

Healthy

United States
Akros Pharma Inc.

Terminated

Two Week Study Evaluating Safety, Tolerability and Pharmacokinetics of Multiple Doses of JTK-853 in Healthy Subjects

Healthy

United States
Akros Pharma Inc.

Completed

Safety and Efficacy Study of JTT-705 in Combination With Simvastatin 40 mg in Patients With Low High-Density Lipoprotein (HDL) Levels

Dyslipidemia

Netherlands
Akros Pharma Inc.

Completed

Efficacy and Safety Study of JTT-705 in Combination With Pravastatin 40 mg in Patients With Type II Hyperlipidemia

Type II Hyperlipidemia

Netherlands
Akros Pharma Inc.

Completed

Safety and Efficacy Study of JTT-705 in Combination With Atorvastatin 20 mg in Patients With Low High-Density Lipoprotein (HDL) Levels

Dyslipidemia

Netherlands
Akros Pharma Inc.

Completed

Study to Evaluate the Efficacy and Safety of JTE-451 in Subjects With Moderate to Severe Plaque Psoriasis (IMPACT-PS)

Skin Diseases | Psoriasis | Plaque Psoriasis

United States, Canada, Poland
Akros Pharma Inc.

Terminated

Study to Evaluate the Safety and Efficacy of JTE-051 in Subjects With Moderate to Severe Plaque Psoriasis (CLEAR-PS)

Skin Diseases | Plaque Psoriasis

United States, Canada
Akros Pharma Inc.

Completed

Study to Evaluate Efficacy, Safety and Tolerability of JTE-051 in Subjects With Active Rheumatoid Arthritis (MOVE-RA)

Rheumatoid Arthritis

Ukraine, United States, Argentina, Bulgaria, Romania, Peru, Russian Federation, Mexico, Colombia, Poland
Akros Pharma Inc.

Completed

Study to Evaluate Safety,Tolerability,Pharmacodynamics & Pharmacokinetics of JTE-451 in Active Plaque Psoriasis Subjects

Skin Diseases | Psoriasis | Plaque Psoriasis

Canada
Akros Pharma Inc.

Terminated

Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Oral Doses of JTT-252

Diabetes Mellitus

United States
Akros Pharma Inc.

Completed

Safety, Tolerability, PK & PD Study of JTZ-951 in Anemic Subjects With End-stage Renal Disease

Anemia of Chronic Kidney Disease

United States
Akros Pharma Inc.

Completed

Safety and Efficacy Study of JTT-851 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Akros Pharma Inc.

Completed

Safety Study of JTT-302 in Subjects With Low HDL-C Levels

Dyslipidemia

United States
Akros Pharma Inc.

Completed

Study to Assess Safety,Tolerability,Pharmacokinetics & Antiviral Activity of JTK-853 in Hepatitis C Virus Genotype 1 Infected Subjects

Hepatitis C Virus Infection, Response to Therapy of

Puerto Rico
Anwita Biosciences
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Phase 1 First-in-human Study of JS014

Lymphoma | Solid Tumor, Adult | Neoplasm Malignant | Neoplasm, Experimental

Taiwan
Emoled
University of Pisa; Istituto di Fisiologia Clinica CNR; Akros Bioscience; Phidea...

Completed

Blu Light for Ulcers Reduction (BLUR)

Leg Ulcers Venous | Dehiscence, Surgical Wound

Italy
Karos Pharmaceuticals

Completed

Single and Multiple Ascending Doses Clinical Pharmacology Study With KAR5585

Pulmonary Arterial Hypertension

United States
Akron General Medical Center
Akron Children's Hospital

Terminated

Computational Simulation of Patellar Instability

Patellar Instability

United States
Coherus Biosciences, Inc.
Shanghai Junshi Bioscience Co., Ltd.; Medpace, Inc.

Active, not recruiting

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

Hepatocellular Carcinoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor

United States
Akron Children's Hospital

Recruiting

Meaning Making While Your Child is in Intensive Care

Narrative Medicine

United States
Akron Molecules AG

Completed

A Placebo Controlled, Double Blind, Randomised, 8-week Phase IIa Proof of Concept Study to Assess the Efficacy and Safety of AKR 202 in Patients With Osteoarthritis Pain

Osteoarthritis

Austria
Akron Children's Hospital

Withdrawn

Prochlorperazine Versus Prochlorperazine & Ketorolac in Treatment of Pediatric Migraine in the Emergency Department

Migraine

United States
Akron Children's Hospital

Completed

Influenza Vaccination for Parents and Other Caregivers in the Pediatric Medical Home

Influenza

United States
Akron Children's Hospital

Completed

The Use of Nasal Phenylephrine in Infants With Bronchiolitis

Bronchiolitis
Akron Children's Hospital

Completed

Incidence of Rhabdomyolysis Among Patients Admitted With Jimsonweed Ingestions

Hemoglobinuria | Rhabdomyolysis | Myoglobinuria

United States
Akros Pharma Inc.
ICON Clinical Research

Recruiting

Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction (POWER-HF)

Chronic Heart Failure

United States
Apros Therapeutics, Inc

Completed

A Dose Escalation Study of APR003 in Patients With Advanced Colorectal Cancer (CRC) With Malignant Liver Lesions

Advanced Colorectal Carcinoma

United States
Akron Children's Hospital

Completed

Ultrasound Guided Adductor Canal Versus Femoral Nerve Blocks for Anterior Cruciate Ligament Reconstruction in Pediatrics

Post-operative Pain | Quadriceps Muscle Strength

United States
Akron Children's Hospital

Completed

COntinuous vs BOlus Nasogastric Feeding in Mechanically Ventilated Pediatric Patients 2 (COBO2)

Dietary Modification

United States
Akron Children's Hospital

Terminated

The Use of Exhaled Nitric Oxide in Conjunction With the Asthma Control Test to Determine Asthma Control in Pediatric Patients

Asthma

United States
Akron Children's Hospital

Completed

Efficacy of IV Lidocaine at Alleviating Pain Associated With Propofol Infusion in Pediatric Patients Undergoing Sedation

Pain

United States
Akron Children's Hospital

Terminated

Comparison of the Efficacy of Topical Ibuprofen to Oral Ibuprofen in Adolescent Athletes

Soft Tissue Injury

United States
Akron Children's Hospital

Completed

Effectiveness and Cost Study Comparing Two Ways to Deliver Albuterol for the Treatment of Asthma in the Hospital

Status Asthmaticus

United States
Akron Children's Hospital

Completed

Sedation for Brainstem Evoked Auditory Response (BEAR) Testing Using Intravenous Pentobarbital

Childrens 0 to 18 Years of Age Who Require Moderate Sedation

United States
Akron Children's Hospital

Completed

A Critical Appraisal of the Role of Near Infrared Spectroscopy (NIRS) in the Pediatric Intensive Care Unit (PICU)

Pediatric Intensive Care Unit

United States
Akron Children's Hospital

Completed

Topical Brinzolamide Ophthalmic Suspension Versus Placebo in the Treatment of Infantile Nystagmus Syndrome

Infantile Nystagmus Syndrome

United States
Akron Children's Hospital

Completed

Treatment of Acetaminophen Toxicity With N-acetylcysteine

Acetaminophen Toxicity

United States
Akron Children's Hospital

Not yet recruiting

Pneumoperitoneum Management With SurgiQuest AirSeal® at Low vs. Higher Pressure (PRESSURE)

Shoulder Pain

United States
Akron Children's Hospital

Completed

Treatment of APAP Toxicity With IV and Oral NAC 2008-2011

Acetaminophen Toxicity

United States
Akron Children's Hospital

Completed

Continued Study of Artificial Vision: Evaluation of the BrainPort® System and Investigation of Visual Ambulation (BrainPort)

Blindness

United States
Akron Children's Hospital

Completed

Vitamin D Serum Concentrations & Supplementation in Children With Cerebral Palsy

Vitamin D Deficiency

3

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