Clinical Trials Sponsored by Aspire Medical

Total 56404 results

Shire

Active, not recruiting

A Study of Replagal in Children and Adults With Fabry Disease in India

Fabry Disease

India
Shire

Terminated

Safety and Efficacy Study of rhPTH(1-84) in Subjects With Hypoparathyroidism

Hypoparathyroidism

United States, Hungary, Denmark, Canada
Shire

Completed

Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP) (PEDAL)

Retinopathy of Prematurity (ROP)

United States, Italy, Netherlands, Poland, Sweden, United Kingdom
Shire

Terminated

Efficacy and Safety Study of Ontamalimab as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307) (CARMEN CD 307)

Crohn's Disease

Spain, United States, Korea, Republic of, Australia, Romania, Hungary, Israel, Italy, Croatia, Belgium, Bulgaria, Germany, Poland, Portugal, Argentina, United Kingdom, Greece, New Zealand, Austria, Bosnia and Herzegovina, Colombia, Eston... and more
Shire

Completed

Efficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment With Ganciclovir, Valganciclovir, Foscarnet, or Cidofovir

Cytomegalovirus (CMV)

United States, Italy, France, Spain, Australia, Germany, Canada, United Kingdom, Belgium, Croatia, Austria, Denmark, Singapore, Switzerland
Shire

Completed

A Study Evaluating the Efficacy of SAR 1118 (0.1%, 1.0%, 5.0%) Ophthalmic Solution in Subjects With Dry Eye Conducted in a Controlled Adverse Environment (CAE)

Dry Eye

United States
Shire

Completed

Exploratory Multi-centre Trial In Patients With ET Treated With XAGRID® (EMIX)

Essential Thrombocythemia (ET)

Italy
Shire

Completed

A Relative Bioavailability Study of SSP-004184AQ (Magnesium Salt) and SSP-004184SS (Disodium Salt)

Healthy

United States
Shire

Completed

SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Binge Eating Disorder

United States, Germany
Shire

Completed

Sulfamethoxazole Drug Interaction Study With MMX® Mesalazine/Mesalamine

Healthy

United States
Shire

Withdrawn

A Study of SPD465 in Young Adult Drivers With Attention-Deficit Hyperactivity Disorder (ADHD) Using Driving Simulators

Attention Deficit Hyperactivity Disorder

United States
Shire

Completed

Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity

Chronic Constipation

United States, Belgium, United Kingdom
Shire

Completed

A Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) Enzyme Replacement Therapy in Gaucher Disease

Gaucher Disease, Type 1

Israel, Paraguay, Argentina, Russian Federation, Tunisia
Shire

Terminated

Study for Transfusionally Iron Overloaded Children, Adolescents and Adults Using FBS0701 (SSP-004184)

Iron Overload Due to Repeated Red Blood Cell Transfusions

Canada, United States, Thailand, Italy, United Kingdom
Shire

Completed

The Pharmacokinetics of Anagrelide in Elderly and Young Patients With Essential Thrombocythaemia (ET)

Essential Thrombocythaemia

Sweden, United Kingdom, Spain
Shire

Completed

A Safety and Dose Ranging Study of Idursulfase (Intrathecal) Administration Via an Intrathecal Drug Delivery Device in Pediatric Patients With Hunter Syndrome Who Have Central Nervous System Involvement and Are Receiving Treatment With Elaprase®

Hunter Syndrome

United States, United Kingdom
Shire

Completed

Study of PVS-10200 for the Treatment of Restenosis in Patients With Peripheral Artery Disease (TRIUMPH) (TRIUMPH)

Peripheral Artery Disease

France
Shire

Completed

Pharmacokinetic Interaction Between SSP-004184 (SPD602) and Midazolam in Healthy Adult Subjects

Healthy

United States
Shire

Completed

AME (Absorption, Metabolism, and Excretion) of Radiolabeled SSP-004184

Healthy

United States
Shire

Completed

A Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE

Hereditary Angioedema

United States
Shire

Completed

Safety and Tolerability of SPD476 in Maintaining Remission in Patients With Ulcerative Colitis.

Colitis, Ulcerative
Shire

Completed

A Long Term Study of Lanthanum Carbonate in Patients Requiring Dialysis Who Have Ived Lanthanum Carbonate in Previous Studies Defined by the Protocol.

Kidney Failure, Chronic
Shire

Terminated

Long-term Safety of SPD489 When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia

Schizophrenia

United States
Shire

Completed

A Drug Interaction Study of SPD503 and Vyvanse Administered Alone and In Combination in Normal Healthy Volunteers

Healthy

United States
Shire

Completed

A Classroom Study to Assess the Time of Onset of Vyvanse (Lisdexamfetamine Dimesylate) in Pediatric Subjects Aged 6-12 With Attention Deficit/Hyperactivity Disorder (ADHD)

ADHD

United States
Shire

Completed

Evaluate the Maintenance of Efficacy of SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Binge Eating Disorder

United States, Spain, Germany, Canada, Sweden
Shire

Completed

Randomized, Double-blind Safety and Efficacy Study of Lisdexamfetamine Dimesylate (LDX) in Children and Adolescents Aged 6-17

ADHD

Belgium, France, Germany, Hungary, Italy, Netherlands, Poland, Spain, Sweden, United Kingdom
Shire

Completed

Strategies in Maintenance for Patients Receiving Long-term Therapy (S.I.M.P.L.E.) With MMX (Multi-Matrix System) Mesalamine for Ulcerative Colitis (UC)

Ulcerative Colitis

United States
Shire

Completed

Multicenter Study of HGT-1110 Administered Intrathecally in Children With Metachromatic Leukodystrophy (MLD) (IDEAMLD)

Metachromatic Leukodystrophy (MLD)

Australia, Denmark, Japan, France, Germany
Shire

Completed

Vyvanse Adolescent Open-Label Safety and Efficacy Extension Study

ADHD

United States
Shire

Completed

Vyvanse and Adderall XR Given Alone and in Combination With Prilosec OTC

Healthy Volunteers

United States
Shire

Completed

Lisdexamfetamine Dimesylate (LDX) Pilot Cognition Study to Evaluate the Utility of a Standardized Battery of Tests in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)

Attention-Deficit Hyperactivity Disorder

United States
Shire

Terminated

Extension of Study HGT-SAN-055 Evaluating Administration of rhHNS in Patients With Sanfilippo Syndrome Type A (MPS IIIA)

Sanfilippo Syndrome

Netherlands, United Kingdom
Shire

Completed

A Drug Interaction Study of SPD503 and Concerta Administered Alone and In Combination in Normal Healthy Volunteers

Healthy

United States
Shire

Completed

French Observational Xagrid (FOX) Study In Adult Patients With Essential Thrombocythemia (FOX)

Essential Thrombocythemia

France
Shire

Completed

Co-Administration of LDX (SPD489) and Venlafaxine XR (EFFEXOR XR) in Healthy Volunteers

Healthy

United States
Shire

Completed

Safety and Efficacy of SPD476 (Mesalazine) Given Twice Daily (2.4 g/Day) vs SPD476 Given as a Single Dose (4.8 g/Day) in Subjects With Acute Mild to Moderate Ulcerative Colitis

Colitis, Ulcerative

United States
Shire

Completed

Study of Safety and Efficacy of a rhPTH[1-84] of Fixed Doses of 25 and 50 mcg in Adults With Hypoparathyroidism (RELAY)

Hypoparathyroidism

United States
Shire

Completed

Evaluation of Safety and Activity of Celaderm in Healing Venous Leg Ulcers

Leg Ulcer | Varicose Ulcer

United States
Shire

Completed

A Study Of PF-00547659 In Patients With Moderate To Severe Ulcerative Colitis (TURANDOT)

Ulcerative Colitis

United States, France, Spain, Canada, Korea, Republic of, Australia, Germany, New Zealand, Serbia, Belgium, Czechia, Poland, Hungary, Austria, Bulgaria, Israel, Italy, Netherlands, South Africa, Russian Federation, Slovakia
Shire

Completed

A Study for Patients With Neurogenic Orthostatic Hypotension

Hypotension, Orthostatic

United States
Shire

Completed

A Pilot Study to Evaluate the Use of C1 Esterase Inhibitor (Human) in Patients With Acute Antibody-Mediated Rejection

Graft Rejection

United States, Germany
Shire

Terminated

Evaluation of Ecallantide for Treatment of Angiotensin Converting Enzyme (ACE) Inhibitor Induced Angioedema

ACE Inhibitor Induced Angioedema

United States
Shire

Completed

Efficacy and Safety of Two Doses of SPD476 (Mesalazine) 2.4g and 4.8g Once Daily, With Reference to Asacol 0.8g Three Times Daily in Subjects With Acute, Mild to Moderate Ulcerative Colitis

Ulcerative Colitis

Belgium
Shire

Terminated

Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation (OIC)

Opioid Induced Constipation | Non-cancer Pain

Belgium
Shire

Completed

Safety and Efficacy of SPD503 in Treating Attention-Deficit/Hyperactivity Disorder (ADHD) in Children Aged 6-17

Attention Deficit Disorder With Hyperactivity
Shire

Completed

Absorption, Metabolism and Excretion (AME) of Single Dose Radiolabeled Prucalopride Succinate in Volunteers

Healthy

United States
Shire

Completed

Safety and Efficacy Study of VP20621 for Prevention of Recurrent Clostridium Difficile Infection

Clostridium Difficile Infection

United States, Belgium, Canada, Germany, Switzerland, Spain
Shire

Completed

Troxacitabine in Treating Patients With Chronic Myelogenous Leukemia

Leukemia

United States, Canada
Shire

Completed

Study of SSP-004184 (FBS0701) in Healthy Adults and Elderly Subjects and in Subjects With Impaired Renal Function

Impaired Renal Function

United States

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