Clinical Trials Sponsored by BioCryst Pharmaceuticals

Total 19607 results

Patricia I. Dickson, M.D.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Completed

A Study of Intrathecal Enzyme Therapy for Cognitive Decline in MPS I

Mucopolysaccharidosis I | Scheie Syndrome | Lysosomal Storage Disease | Cognitive Decline | Hurler-Scheie Syndrome

United States
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Affiliated Hospital... and other collaborators

Unknown

A Study of PEG-somatropin Injection to Treat Children of Turner Syndrome

Turner Syndrome

China
Frank G. Holz
Radboud University Medical Center; Bayer; Hoffmann-La Roche; Novartis Pharmaceuticals and other collaborators

Active, not recruiting

Development of Novel Clinical Endpoints in Intermediate AMD (MACUSTAR)

Age Related Macular Degeneration (AMD)

Germany, Italy, Netherlands, United Kingdom, France, Portugal, Denmark
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; First Affiliated... and other collaborators

Unknown

Efficacy and Safety of rhGH (Jintropin®) in Pediatric Participants With ISS

Dwarfism

China
Prof Brian Lawlor
King's College London; Göteborg University; University College Dublin; Aristotle... and other collaborators

Completed

A Phase III Trial of Nilvadipine to Treat Alzheimer's Disease (NILVAD)

Alzheimer's Disease

Germany, Ireland, United Kingdom, France, Greece, Hungary, Italy, Netherlands, Sweden
GeneScience Pharmaceuticals Co., Ltd.
Peking University First Hospital; Peking Union Medical College Hospital; The... and other collaborators

Unknown

A Non-inferiority Phase 2 Study to Evaluate the Safety and Efficacy of PEG-rhGH in the Treatment of AGHD

Adult Growth Hormone Deficiency

China
Fudan University
The First Affiliated Hospital of Anhui Medical University; Guangdong Provincial... and other collaborators

Withdrawn

Compare S-1 for 6 Months to 1 Year as Adjuvant Chemotherapy After D2 Resection in Patients With Gastric Cancer Staged II , IIIA or IIIB.

Gastric Cancer

China
Peking Union Medical College Hospital
Beijing Tongren Hospital; Shanghai Fosun Pharmaceutical Industrial Development... and other collaborators

Recruiting

Rituximab Combined With Cyclosporine Versus Rituximab Alone in the Treatment of iMN

Idiopathic Membranous Nephropathy

China
Guangdong Provincial People's Hospital
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; Zhongshan People's... and other collaborators

Unknown

Long-term MOno-Antiplatelet Drug Strategy After PerCutanEous CoronAry InterveNtion (RESCIND-OCEAN)

Antiplatelet Drug-related Gastrointestinal Injury

China
Zhujiang Hospital
Wuhan University; First Affiliated Hospital, Sun Yat-Sen University; Sun Yat-Sen... and other collaborators

Unknown

Clinical Observation for the Therapeutic Effect of mNGF on Cognitive Decline in Cerebral Small Vessel Disease

Cerebral Small Vessel Diseases

China
Institut National de la Santé Et de la Recherche...
Assistance Publique - Hôpitaux de Paris; Cardiff University; Karolinska Institutet and other collaborators

Withdrawn

TINN2: Treat Infection in NeoNates 2 (TINN2)

Bronchopulmonary Dysplasia

Belgium, France, Germany, Hungary, Italy, Luxembourg, Netherlands, Sweden, United Kingdom
Haukeland University Hospital
The Research Council of Norway; The Royal Norwegian Ministry of Health; Norwegian... and other collaborators

Completed

WENBIT - Western Norway B Vitamin Intervention Trial (WENBIT)

Myocardial Infarction | Coronary Artery Disease | Cerebrovascular Stroke

Norway
Shenzhen Kangzhe Pharmaceutical Co., Ltd.
Hunan Cancer Hospital; Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University and other collaborators

Recruiting

Bioequivalence Study of Doxorubicin Hydrochloride Liposome Injection (Lipodox®) in Chinese Patients

Breast Cancer | Ovarian Cancer

China
corlife
University of Zurich; Universitaire Ziekenhuizen KU Leuven; Hannover Medical... and other collaborators

Completed

European Clinical Study for the Application of Regenerative Heart Valves - ESPOIR (ESPOIR)

Heart Valve Disease

Germany, Belgium, Netherlands, France, Italy, Moldova, Republic of, Switzerland, United Kingdom
Children's Hospital of Philadelphia
Eli Lilly and Company; University of Pennsylvania; Takeda; National Institute of... and other collaborators

Recruiting

The Myelin Disorders Biorepository Project (MDBP)

Mucopolysaccharidoses | Leukoencephalopathies | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2... and other conditions

United States
Boryung Pharmaceutical Co., Ltd
Asan Medical Center; Ulsan University Hospital; Korea University Anam Hospital; Dong-A University and other collaborators

Completed

A Multicenter, Phase 3 Study to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan(BR-A-657∙K) 30mg Compared to Placebo in Patients With Mild to Moderate Essential Hypertension (fimasartan)

Hypertension

Korea, Republic of
The First Affiliated Hospital of Guangzhou Medical...
The Affiliated Hospital of Qingdao University; The Affiliated Nanjing Drum... and other collaborators

Unknown

Efficacy and Safety Study of Sodium Tanshinone IIA Sulfonate on Pulmonary Hypertension (STS)

Cardiovascular Diseases | Lung Diseases | Pulmonary Arterial Hypertension | Pulmonary Hypertension | Tanshinone IIA Sulfonate

China
University of Oxford
Assistance Publique - Hôpitaux de Paris; University of Nottingham; Novartis; Pf... and other collaborators

Active, not recruiting

LITMUS Imaging Study

NAFLD | Fibrosis, Liver | NASH - Nonalcoholic Steatohepatitis | NASH | Steatosis of Liver

United Kingdom, Finland, Sweden, Spain, Greece, United States, Switzerland, Italy, France, Germany
Memorial Sloan Kettering Cancer Center
University of California, Los Angeles; Ferring Pharmaceuticals; Wayne State University and other collaborators

Completed

3-arm Study of Abiraterone Acetate Alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix Alone for Patients With Prostate Cancer With a Rising PSA or a Rising PSA and Nodal Disease Following Definitive Radical Prostatectomy

Prostate Cancer

United States
Guangdong Provincial People's Hospital
Shenzhen People's Hospital; Affiliated Cancer Hospital of Shantou University... and other collaborators

Not yet recruiting

Dynamic Follow-up of Symptoms Based on Patient-reported Outcomes in Immunotherapy for Esophageal Cancer: a Prospective Multicentre Cohort Study (SPRING)

Esophageal Cancer | Immunotherapy | Patient-reported Outcomes

China
Beijing YouAn Hospital
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Renmin... and other collaborators

Unknown

The Clinical Study of Carrimycin on Treatment Patients With COVID-19

Novel Coronavirus Infectious Disease (COVID-19)
University of Pennsylvania
Novo Nordisk A/S; Albert Einstein College of Medicine; Northwestern University; Yale University and other collaborators

Recruiting

Transformative Research in Diabetic Nephropathy (TRIDENT)

Diabetic Nephropathies | Diabetic Glomerulosclerosis

United States
Altoida
University of Roma La Sapienza; Fundacion Clinic per a la Recerca Biomédica; Neuromed... and other collaborators

Completed

Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI) (AltoidaML)

Cognitive Impairment | Dementia | Alzheimer Disease | Mild Cognitive Impairment | Memory Disorders | Presymptomatic Disease
GeneScience Pharmaceuticals Co., Ltd.
Peking University First Hospital; Shengjing Hospital; The First Affiliated Hospital... and other collaborators

Unknown

A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Short Stature Children Due to Chronic Kidney Disease Before Transplantation

Dwarfism

China
JW Pharmaceutical
Chonbuk National University Hospital; Samsung Medical Center; Asan Medical Center and other collaborators

Completed

to Evaluate the Safety and Efficacy of Pitavastatin in Patients With IFG and Hyperlipidemia (SIPHON)

HbA1c Level Associated With Lipid Compositions

Korea, Republic of
Boryung Pharmaceutical Co., Ltd
Chonbuk National University Hospital; Samsung Medical Center; Asan Medical Center and other collaborators

Completed

A Clinical Study to Evaluate Efficacy and Safety of Fimasartan/Hydrochlorothiazide Combination-therapy

Essential Hypertension

Korea, Republic of
Sun Yat-sen University
The First Affiliated Hospital of Anhui Medical University; Guangdong Provincial... and other collaborators

Completed

Extensive Intraoperative Peritoneal Lavage After Curative Gastrectomy for Locally Advanced Gastric Cancer (SEIPLUS) (SEIPLUS)

Gastric Cancer

China
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
Shanghai Hutchison Pharmaceuticals Limited
Shanghai Changzheng Hospital; The First Hospital of Hebei Medical University; Shanxi Cardiovascular Hospital and other collaborators

Completed

Efficacy and Safety of Shexiang Baoxin Pill in Patients With Ischemia With Non-Obstructive Coronary Artery (LESS)

Angina Pectoris | Coronary Heart Disease | X Syndrome, Angina | Ischemia With Non-Obstructive Coronary Artery

China
Harbin Medical University
LanZhou University; Hebei General Hospital; The First Hospital of Jilin University and other collaborators

Active, not recruiting

EROSION II: OCT Guided PPCI in STEMI

ST-segment Elevation Myocardial Infarction

China
Peking University People's Hospital
Sun Yat-sen University; Cancer Institute and Hospital, Chinese Academy of Medical... and other collaborators

Unknown

Sentinel Lymph Node Mapping In Cervical Cancer (SLNMICC)

Uterine Cervical Neoplasms

China
Peking University People's Hospital
Sun Yat-sen University; Cancer Institute and Hospital, Chinese Academy of Medical... and other collaborators

Unknown

Sentinel Lymph Node Mapping In Endometrial Cancer (SLNMIEC)

Endometrial Neoplasms

China
Nanjing Luye Sike Pharmaceutical Co., Ltd.
China Medical University, China; Xijing Hospital; The Second Hospital of Hebei... and other collaborators

Unknown

Phase III Study of Vincristine Sulfate Liposome For Injection In Adults With Naïve Acute Lymphoblastic Leukemia (LY01609)

Adult Acute Lymphoblastic Leukemia

China
Prof. Dr. Winfried Meissner
University Hospital, Geneva; University Hospital Inselspital, Berne; Novartis... and other collaborators

Completed

Providing Standardized Consented PROMs (Patient Reported Outcome Measures) for Improving Pain Treatment (PROMPT)

Pain, Postoperative

Germany
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Tongji Hospital and other collaborators

Unknown

A Study of Gentuximab + Paclitaxel in Patients With Advanced Gastric or Gastroesophageal Junction Cancer

Advanced Gastric or Gastroesophageal Junction Cancer

China
Sun Yat-sen University
Peking University; Zhejiang Cancer Hospital; Xiangya Hospital of Central South... and other collaborators

Not yet recruiting

Nedaplatin Versus Cisplatin and Capecitabine Versus Fluorouracil in IC + CCRT for Locoregionally Advanced NPC (NX-NPC)

Nasopharyngeal Carcinoma

China
Boryung Pharmaceutical Co., Ltd
Chonbuk National University Hospital; Samsung Medical Center; Asan Medical Center and other collaborators

Completed

Clinical Study to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan in Hypertension Patients

Hypertension
Alessandro Doria
University of Colorado, Denver; University Health Network, Toronto; University... and other collaborators

Not yet recruiting

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease (SUGARNSALT)

Heart Failure | Diabetic Nephropathies | Kidney Failure, Chronic | Diabetes Mellitus Type 1

Canada, United States
GeneScience Pharmaceuticals Co., Ltd.
First People's Hospital of Hangzhou; Xiangya Hospital of Central South University and other collaborators

Unknown

Clinical Study of Pegylated Somatropin to Treat Children Growth Hormone Deficiency

Growth Hormone Deficiency

China
Sun Yat-sen University
Peking University; Xiangya Hospital of Central South University; Henan Cancer... and other collaborators

Active, not recruiting

Single-agent Capecitabine as Adjuvant Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma (CAN)

Nasopharyngeal Carcinoma

China
Intech Biopharm Ltd.
Peking University People's Hospital; Beijing Friendship Hospital; The Second... and other collaborators

Completed

Clinical Equivalence of Budesonide HFA MDI Versus Budesonide Turbuhaler in Mild to Moderate Chinese Asthma Patients

Asthma

China
Boryung Pharmaceutical Co., Ltd
Pusan National University Hospital; Asan Medical Center; Chonnam National University... and other collaborators

Completed

Fimasartan/Amlodipine Combination Phase III

Essential Hypertension

Korea, Republic of
University College, London
London School of Hygiene and Tropical Medicine; Radboud University Medical... and other collaborators

Recruiting

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB (PARADIGM4TB)

Pulmonary Tuberculosis

South Africa
Boryung Pharmaceutical Co., Ltd
Samsung Medical Center; Asan Medical Center; Chonnam National University Hospital and other collaborators

Completed

A Randomized, Double-Blind, Placebo-Controlled, 3x3 Factorial Design, Phase II Study to Evaluate the Antihypertensive Efficacy and Safety of Combination of Fimasartan and Amlodipine in Patients With Essential Hypertension

Hypertension

Korea, Republic of
University of Minnesota
National Health and Medical Research Council, Australia; Bristol-Myers Squibb; National Institutes of Health Clinical Center (CC) and other collaborators

Completed

Strategic Timing of Antiretroviral Treatment (START)

HIV Infection

Spain, United States, United Kingdom, Ireland, Australia, Argentina, Denmark, Sweden, Israel, Switzerland, Germany, Brazil, Norway, Chile, Thailand, Peru, Portugal, Greece, Luxembourg, Uganda, Austria, Belgium, Czechia, Estonia, Finland, ... and more
Institute of Hematology & Blood Diseases Hospital...
Xijing Hospital; Xi'an Central Hospital; The Second Hospital of Hebei Medical... and other collaborators

Active, not recruiting

A Randomized Trial Comparing Optimized rhTPO Treatment With Eltrombopag Treatment in Pre-treated ITP Pts (TE-ITP)

Previously Treated Primary Immune Thrombocytopenia

China
Dong Wha Pharmaceutical Co. Ltd.
Chonbuk National University Hospital; Asan Medical Center; Chonnam National University... and other collaborators

Completed

A Study to Evaluate Efficacy and Safety Profile of Zabofloxacin Tablet 400mg and Moxifloxacin Tablet 400mg (DW224-III-3)

Chronic Obstructive Pulmonary Disease

Korea, Republic of
Xinqiao Hospital of Chongqing
Peking University First Hospital; LanZhou University; RenJi Hospital; Qilu Hospital... and other collaborators

Unknown

Study on the Anti-HPA Antibodies Caused Neonatal Alloimmune Thrombocytopenia in Chinese Pregnant Women

Neonatal Alloimmune Thrombocytopenia
Dongzhimen Hospital, Beijing
Wuhan Third Hospital; The Second Affiliated Hospital of Tianjin University... and other collaborators

Unknown

BuqitongluO Granule for Qi Deficiency and Blood Stasis Syndrome (BOSS)

Coronary Artery Disease | Diabetic Peripheral Neuropathy | Stroke, Ischemic | Angina Pectoris, Stable

China
Centre Hospitalier Universitaire de Besancon
Novartis Pharmaceuticals; National Cancer Institute, France; National Research... and other collaborators

Terminated

Multicenter Prospective Cohort of Informal Caregivers in Burgundy and Franche-Comté (ICE)

Breast Cancer | Ischemic Stroke | Parkinson Disease | Age-related Macular Degeneration | Colorectal Cancer | Alzheimer Disease | Prostate Cancer | Hemorrhagic Stroke | Cardiac Disease

France

Clinical Trials Sponsored by BioCryst Pharmaceuticals

Sponsors and Collaborators

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