Clinical Trials Sponsored by CRS Clinical Research Services Mannheim GmbH

Total 51 results

Cytonet GmbH & Co. KG
CRS Clinical Research Services Mannheim GmbH

Completed

Study in Healthy Subjects, Patients With Urea Cycle Disorders (UCD) and Carriers of UCD Mutations to Evaluate Urea Cycle Function

Urea Cycle Disorders

Germany
Atrogi AB
Key2Compliance; CRS Clinical Research Services

Completed

First-in-human Single and Multiple Dose Trial of ATR-258

Type 2 Diabetes Mellitus

Germany
ISAR-M GmbH
CRI-The Clinical Research Institute GmbH

Not yet recruiting

Thyroid HEmorrhage DetectOr Study (HEDOS)

Thyroid
ResMed
CRI-The Clinical Research Institute GmbH

Recruiting

HomeVent ( Connect) Registry: EU COPD Home NIV Registry (HOmeVent)

Chronic Obstructive Pulmonary Disease

Germany
ResMed
CRI-The Clinical Research Institute GmbH

Completed

Treatment of Predominant Central Sleep Apnoea by Adaptive Servo Ventilation in Patients With Heart Failure (Serve-HF)

Heart Failure | Sleep Disordered Breathing

Germany, Netherlands, Australia, Denmark, France, United Kingdom, Switzerland, Norway, Finland, Sweden, Czechia
Anderson Clinical Research
Boehringer Mannheim

Completed

The Safety and Effectiveness of Fozivudine Tidoxil in HIV-1 Infected Patients

HIV Infections
Lohmann & Rauscher
CRI-The Clinical Research Institute GmbH

Not yet recruiting

Suprasorb® CNPendo Used for Negative Pressure Therapy in the Oesophagus and Rectum to Support Defect and Wound Healing (Velox)

Esophagus Injury | Rectal Lesion
keepMED Ltd.
CRI-The Clinical Research Institute GmbH

Not yet recruiting

Efficacy and Safety of keepMED Positive Airway Pressure Device in Patients With Obstructive Sleep Apnea (keePaOSA)

Obstructive Sleep Apnea
Doasense GmbH
Clinical Research Services, Mannheim, Germany; Institute Medical Statistics... and other collaborators

Completed

In Vitro Diagnostic Test for DOAC in Urine (PADOASU)

Anticoagulant Therapy

Germany
Silence Therapeutics GmbH
FGK Clinical Research GmbH; Granzer Regulatory Consulting & Services

Completed

Atu027 Plus Gemcitabine in Advanced or Metastatic Pancreatic Cancer (Atu027-I-02) (Atu027-I-02)

Carcinoma, Pancreatic Ductal

Germany
Paion UK Ltd.
Simbec Research; ORION Clinical Services; Creative Clinical Research GmbH

Completed

Efficacy and Safety of Remimazolam (CNS7056) Compared to Propofol for Intravenous Anesthesia During Elective Surgery

Anesthesia, Intravenous

Germany
Herantis Pharma Plc.
Clinical Research Services Turku - CRST Oy

Completed

Single Ascending Doses of HER-096 in Healthy Subjects

Parkinson Disease

Finland
RHEACELL GmbH & Co. KG
FGK Clinical Research GmbH; Ticeba GmbH; Granzer Regulatory Consulting & Services

Terminated

Allogeneic ABCB5-positive Stem Cells for Treatment of PAOD

Peripheral Arterial Occlusive Disease

Germany, Austria, Czechia, Poland, United Kingdom
RHEACELL GmbH & Co. KG
FGK Clinical Research GmbH; Ticeba GmbH; Granzer Regulatory Consulting & Services

Active, not recruiting

Allogeneic ABCB5-positive Limbal Stem Cells for Treatment of LSCD

Limbal Stem Cell Deficiency

United States, Germany
RHEACELL GmbH & Co. KG
FGK Clinical Research GmbH; Ticeba GmbH; Granzer Regulatory Consulting & Services

Completed

Allogeneic ABCB5-positive Stem Cells for Treatment of CVU

Skin Ulcer Venous Stasis Chronic

Germany
RHEACELL GmbH & Co. KG
FGK Clinical Research GmbH; Ticeba GmbH; Granzer Regulatory Consulting & Services

Terminated

Clinical Trial to Investigate Efficacy and Safety of the IMP in Patients With Non Healing Wounds Originating From Ulcers

Skin Ulcer Venous Stasis Chronic

Germany
RHEACELL GmbH & Co. KG
FGK Clinical Research GmbH; Ticeba GmbH; Granzer Regulatory Consulting & Services

Completed

Allogeneic ABCB5-positive Stem Cells for Treatment of Epidermolysis Bullosa

Recessive Dystrophic Epidermolysis Bullosa

United States, Austria, France, Germany, United Kingdom
RHEACELL GmbH & Co. KG
FGK Clinical Research GmbH; Ticeba GmbH; Granzer Regulatory Consulting & Services

Completed

Allogeneic ABCB5-positive Stem Cells for Treatment of DFU "Malum Perforans"

Diabetic Neuropathic Ulcer

Germany
Pieris Pharmaceuticals GmbH
FGK Clinical Research GmbH; Nuvisan Pharma Services; EUROCALIN Consortium

Completed

First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRS-080

Healthy

Germany
ikfe-CRO GmbH
IKFE Institute for Clinical Research and Development

Unknown

Human Insulin Analogs: Evaluation of Inflammatory mRNA Expression of Macrophages and Endothelial Function of Short-acting Insulin - HERMES Pilot Study (HERMES)

Type 2 Diabetes Mellitus

Germany
ikfe-CRO GmbH
IKFE Institute for Clinical Research and Development

Unknown

Establishing Cardiovascular Biomarkers to Define Preferred Lantus® Use

Insulin-requiring Type 2 Diabetes Mellitus

Germany
ResMed
CRI-The Clinical Research Institute GmbH; University Hospital Regensburg

Completed

Registry on the Treatment of Central and Complex Sleep-Disordered Breathing With Adaptive Servo-Ventilation (READ-ASV)

Obstructive Sleep Apnea | Central Sleep Apnea | Mixed Sleep Apnea | Complex Sleep Apnea

Switzerland, Spain, Denmark, Portugal, France, Germany
ikfe-CRO GmbH
IKFE Institute for Clinical Research and Development

Completed

Beta-Cell Function of Insulin Glargine Compared to Neutral Protamine Hagedorn (NPH) Insuline and to Insulin Detemir in Combination With Metformin

Type 2 Diabetic Patients | Insufficient Metabolic Control | OAD Treatment

Germany
Dr. August Wolff GmbH & Co. KG Arzneimittel
FGK Clinical Research GmbH; Nuvisan GmbH; Charles River Biopharmaceutical Services...

Completed

Investigation of Ascending Concentrations of Glycopyrronium Bromide (GPB) in a Topical Formulation in Subjects With Axillary Hyperhidrosis

Primary Axillary Hyperhidrosis

Germany
Fresenius Medical Care Deutschland GmbH
Winicker Norimed GmbH; James Motta, Clinical Research Associate (CRA)

Completed

Comparison of Efficacy and Tolerability of APD Treatment With Different PD Cyclers

Renal Failure | End Stage Renal Disease

Chile
ResMed
Clinical Trial Center North Hamburg Germany; CRI-The Clinical Research Institute...

Terminated

European Home Mechanical Ventilation Registry (EHMVR)

Pulmonary Disease, Chronic Obstructive | Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Duchenne Muscular Dystrophy | Myotonic Dystrophy | Spinal Cord Injury | Obesity Hypoventilation Syndrome | Kyphoscoliosis | Congenital Central Hypoventilation Syndrome | Myopathies

Germany
ikfe-CRO GmbH
Sanofi; IKFE Institute for Clinical Research and Development

Completed

Beta Cell Relieving and Cardiovascular Protective Effects of LANTUS Treatment in Type 2 Diabetes Patients

Diabetes Mellitus, Type 2

Germany
EsoCap AG
FGK Clinical Research GmbH; FGK Representative Service B.V.

Completed

A Study to Investigate the Efficacy and Tolerability of ESO-101 in Patients With Eosinophilic Esophagitis

Eosinophilic Esophagitis

Spain, Switzerland, Netherlands, Germany, Poland
ikfe-CRO GmbH
AstraZeneca; IKFE Institute for Clinical Research and Development

Unknown

Investigation of a Switch From Insulin Therapy to a Metformin & Saxagliptin Combination in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Germany
ikfe-CRO GmbH
Novartis Pharmaceuticals; IKFE Institute for Clinical Research and Development

Unknown

Effect of Adding Vildagliptin on Beta Cell Function and Cardiovascular Risk Markers in Patients With Moderate Metabolic Control During Metformin Monotherapy

Diabetes Mellitus Type II

Germany
Biotest
Accovion GmbH; ICON plc; SYNLAB Analytics and Services Germany GmbH; Phoenix Clinical... and other collaborators

Completed

Pharmacokinetic, Efficacy and Safety of BT524 in Patients With Congenital Fibrinogen Deficiency

Congenital Afibrinogenemia | Congenital Hypofibrinogenemia

Bulgaria, Egypt, Germany, Lebanon, Tunisia
Dr. August Wolff GmbH & Co. KG Arzneimittel
Bremer Pharmacovigilance Service GmbH; PHARMALOG Institute for Clinical Research

Completed

Safety, Tolerability and Efficacy of Vaginal Suppository WO3191 in the Post-treatment of Bacterial Vaginosis

Vaginosis, Bacterial

Germany
Fresenius Kabi
OE Clinical Trial Center (KKS) Universität Innsbruck; International Medical... and other collaborators

Terminated

Efficacy and Safety Study of a Low-carbohydrate Tube Feed in Critically Ill Patients Under Insulin Therapy

Aneurysmal Subarachnoid Hemorrhage

Austria
ikfe-CRO GmbH
Novo Nordisk A/S; IKFE Institute for Clinical Research and Development

Completed

Impact of Liraglutide on Endothelial Function and Microvascular Blood Flow in Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Germany
A. Vogel AG
CONVEX CRO; d.s.h. statistical services GmbH; MediStat Ltd.; Biodome Clinical; Bo... and other collaborators

Completed

Echinaforce Study to Investigate Explorative Pharmacology and Effectiveness to Prevent From Enveloped Virus Infections

Respiratory Tract Infections | Common Cold

Bulgaria
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

Safety, Tolerability and Pharmacokinetic Profile of Ascending Oral Doses of MMV390048, Part A

Malaria

Australia
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

MMV390048 and Its Antimalarial Activity Against Plasmodium Falciparum in Healthy Adult Subjects, Part B

Malaria

Australia
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265 (OZ/DSMCombo)

Malaria

Australia
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; Queensland Institute...

Terminated

A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection (DSMOZ-2)

Malaria

Australia
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

SJ733 Induced Blood Stage Malaria Challenge Study (SJ733IBSMCS)

Plasmodium Falciparum Malaria

Australia
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

Safety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQP

Malaria

Australia
Bioverativ, a Sanofi company
Assign Data Management and Biostatistics GmbH; Quest Diagnostics-Nichols Insitute and other collaborators

Completed

Safety, Tolerability and Activity of BIVV009 in Healthy Volunteers and Patients With Complement Mediated Disorders (BIVV009-01)

End-stage Renal Disease (ESRD) | Cold Agglutinin Disease (CAD) | Bullous Pemphigoid (BP) | Warm Autoimmune Hemolytic Anemia (WAIHA)

Austria
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer... and other collaborators

Completed

Experimental Falciparum Transmission to Anopheles (EFITA)

Malaria

Australia
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer... and other collaborators

Completed

Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent (OZGAM)

Malaria

Australia
Vakzine Projekt Management GmbH
University of Stellenbosch; Children's Infectious Diseases Clinical Research... and other collaborators

Completed

Study to Evaluate Safety and Immunogenicity of VPM1002 in Comparison With BCG in Newborn Infants in South Africa

Tuberculosis

South Africa
Serum Institute of India Pvt. Ltd.
University of Stellenbosch; South African Tuberculosis Vaccine Initiative; Vakzine... and other collaborators

Completed

Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa

Tuberculosis

South Africa
Folkhälsan Researech Center
Närpes Health Care Center, Närpes, Finland; Department of Social Services and... and other collaborators

Completed

PPP-Botnia Exercise Intervention Study

Family History of Type 2 Diabetes

Finland
Norwegian Institute of Public Health
University of Stellenbosch; European and Developing Countries Clinical Trials... and other collaborators

Recruiting

Evaluation of a Rapid Point-of-Care Serological Triage Test for Active TB (SeroSelectTB)

Tuberculosis, Pulmonary

South Africa, Tanzania, Ethiopia
Mats Heyman
Assistance Publique - Hôpitaux de Paris; Karolinska Institutet; Pfizer; The Swedish... and other collaborators

Recruiting

A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Leukemia, Acute Lymphoblastic

Belgium, United Kingdom, Denmark, Germany, Portugal, Netherlands, Estonia, France, Finland, Iceland, Norway, Sweden, Lithuania, Ireland
Center for Sepsis Control and Care, Germany
Hannover Medical School; German Federal Ministry of Education and Research; University... and other collaborators

Completed

Quality Improvement in Infection COntrol and Sepsis Management in MOdel Regions (icosmos)

Sepsis | Septic Shock | Severe Sepsis

Germany

Clinical Trials Sponsored by CRS Clinical Research Services Mannheim GmbH

Sponsors and Collaborators

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