Clinical Trials Sponsored by Cancer Care Ontario

Total 1914 results

Case Comprehensive Cancer Center

Completed

Hematopoietic Stem Cell Transplant for Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | SCD

United States
Case Comprehensive Cancer Center

Withdrawn

Mycobiome Supporting Diet to Reduce GI Toxicity Associated With ASCT

Myeloma | Autologous Transplant

United States
Case Comprehensive Cancer Center

Active, not recruiting

Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma

Glioma | Glioblastoma

United States
Case Comprehensive Cancer Center

Suspended

Stereotactic Radiosurgery in Treating Patients With Large Brain Metastases

Unspecified Adult Solid Tumor | Tumors Metastatic to Brain

United States
Case Comprehensive Cancer Center

Suspended

Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease

Non-Langerhans-Cell Histiocytosis | Langerhans Cell Histiocytosis (LCH) | Castleman's Disease (CD)

United States
Case Comprehensive Cancer Center

Completed

Intermittent Therapy in Metastatic Renal Cell Carcinoma Patients Treated With Ipilimumab and Nivolumab

Metastatic Renal Cell Carcinoma

United States
Case Comprehensive Cancer Center

Terminated

Proton Based Cardiac Sparing Accelerated Fractionated RadioTherapy in Unresectable NSCLC

Non-Small Cell Lung Cancer

United States
Case Comprehensive Cancer Center

Active, not recruiting

Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma

Glioblastoma

United States
Case Comprehensive Cancer Center

Active, not recruiting

Assessing the Impact of the Microbiome on Breast Cancer Radiotherapy Toxicity

Invasive Breast Cancer | DCIS

United States
Case Comprehensive Cancer Center

Active, not recruiting

FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma

Adenocarcinoma of the Gastroesophageal Junction | Adenocarcinoma of the Esophagus | Stage IIIA Esophageal Cancer | Stage IIIB Esophageal Cancer | Stage IIIC Esophageal Cancer | Adenocarcinoma of the Gastric Cardia

United States
Case Comprehensive Cancer Center

Active, not recruiting

Capecitabine + Bevacizumab in Patients With Recurrent Glioblastoma

Glioblastoma

United States
Case Comprehensive Cancer Center

Completed

Paclitaxel Plus Radiation Therapy in Treating Women With Stage II or Stage III Breast Cancer

Breast Cancer

United States
Case Comprehensive Cancer Center

Active, not recruiting

CPX-351 as a Novel Approach for the Treatment of Older Patients With AML and MDS

Myelodysplastic Syndromes | Refractory Acute Myeloid Leukemia | Relapsed Acute Myelomonocytic Leukemia

United States
Case Comprehensive Cancer Center

Active, not recruiting

Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting

Stage III Melanoma | Stage IV Cutaneous Melanoma

United States
Case Comprehensive Cancer Center

Withdrawn

Captopril Use on the Degree of Marrow Fibrosis in Bone Marrow Fibrosis/Myeloproliferative Neoplasms

Myeloproliferative Neoplasm | Bone Marrow Fibrosis

United States
Case Comprehensive Cancer Center

Suspended

Integrated Imaging System for In Vivo Visualization of Free Flap Perfusion Using Indocyanine Dye

Breast Reconstruction

United States
Case Comprehensive Cancer Center

Completed

Carboplatin, Nab-Paclitaxel and Pembrolizumab for Metastatic Triple-Negative Breast Cancer

Metastatic Triple Negative Breast Cancer

United States
Case Comprehensive Cancer Center

Active, not recruiting

Improving Understanding of Brain Tumors Through Preservation of Biologically Active Brain Tissue

Glioblastoma

United States
Case Comprehensive Cancer Center

Completed

Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention

Acute Myeloid Leukemia | Multiple Myeloma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Myeloproliferative Neoplasm | Acute Biphenotypic Leukemia | Hodgkins Disease

United States
Case Comprehensive Cancer Center

Withdrawn

Dendritic Cell DKK1 Vaccine for Monoclonal Gammopathy and Stable or Smoldering Myeloma

Myeloma | Smoldering Myeloma | Monoclonal Gammopathy

United States
Case Comprehensive Cancer Center

Completed

Axitinib Given on an Individualized Schedule for Metastatic Renal Cell Cancer

Metastatic Renal Cell Cancer

United States
Case Comprehensive Cancer Center

Withdrawn

Prepectoral vs Partial Subpectoral Two-Stage Implant-Based Breast Reconstruction

Breast Reconstruction Following Mastectomy

United States
Case Comprehensive Cancer Center

Withdrawn

Correlation of Imaging Findings With Clinical Findings and Patient Outcomes in Prostate Cancer

Prostate Cancer
Case Comprehensive Cancer Center

Completed

Prehabilitation in Pancreatic Surgery

Pancreatic Resection | Preoperative Frailty

United States
Case Comprehensive Cancer Center

Completed

Assessment of Candidate Protein Expression in Breast Cancer Specimens

Breast Cancer

United States
Case Comprehensive Cancer Center

Completed

Assessment of Novel MRI Quantification Free Breathing Technique in Evaluation of Liver Lesions

Hepatocellular Carcinoma

United States
Case Comprehensive Cancer Center

Terminated

Weight-based Dosing for Dense Weekly Paclitaxel and Carboplatin in Overweight Patients w/ Body Surface Area (BSA) > 2.0

Gynecologic Malignancies

United States
Case Comprehensive Cancer Center

Terminated

Adolescent and Young Adult Survivor Transition (AYAST)

Adolescent and Young Adult Cancer

United States
Case Comprehensive Cancer Center

Completed

Temporally Feathered Radiation Therapy (TFRT) for Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

United States
Case Comprehensive Cancer Center

Completed

Efficacy of Digital Breast Tomosynthesis + Standard 2- Dimensional Mammography in Breast Cancer

Breast Cancer

United States
Case Comprehensive Cancer Center

Completed

Comparison of Yttrium-90 Absorbed Doses Using PET/CT Versus PET/MR Imaging for Hepatic Malignancies

Hepatic Malignancies

United States
Case Comprehensive Cancer Center

Completed

Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer

Prostate Cancer

United States
Case Comprehensive Cancer Center

Withdrawn

Fluciclovine (Axumin) PET/CT vs. NaF PET/CT in Prostate Cancer Osseous Metastatic Disease

Malignant Neoplasm of Prostate

United States
Case Comprehensive Cancer Center

Completed

Improved Intra-operative Safety From Optimal Selection of Anti-slip Surface

Laparoscopic Surgery | Vaginal Surgery

United States
Case Comprehensive Cancer Center

Completed

Debulking Surgery in Ovarian Cancer (MIID-SOC)

Malignant Neoplasm of Ovary | Malignant Neoplasm of Fallopian Tube | Malignant Neoplasm of Peritoneum

United States
Case Comprehensive Cancer Center

Active, not recruiting

Eltrombopag Olamine in Improving Platelet Recovery in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy

Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic... and other conditions

United States
Case Comprehensive Cancer Center

Completed

DRIHNC - Dehydration Reduction in Head & Neck Cancer

Esophageal Cancer | Dehydration | Head & Neck Cancer

United States
Case Comprehensive Cancer Center

Withdrawn

Intervention for Caregivers of Patients Who Have Recently Undergone HSCT

Caregiver Distress | Caregiver Anxiety | Caregiver Health Related QOL
Case Comprehensive Cancer Center

Completed

Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal

Spinal Tumor

United States
Case Comprehensive Cancer Center

Completed

Feasibility of a Social Media-based Weight Loss Program for Low Socioeconomic Status Individuals

Obesity

United States
Case Comprehensive Cancer Center

Completed

KV-CBCT and Ultrasound Imaging in Guiding Radiation Therapy in Patients With Prostate, Liver, or Pancreatic Cancer

Prostate Carcinoma | Adult Liver Carcinoma | Malignant Pancreatic Neoplasm

United States
Case Comprehensive Cancer Center

Completed

Radiation Therapy in Treating Patients With Recurrent Breast Cancer

Breast Cancer

United States
Case Comprehensive Cancer Center

Completed

Radiation Therapy Cisplatin With or Without Fluorouracil Patients With Stage III or Stage IV Head and Neck Cancer

Head and Neck Cancer

United States
Case Comprehensive Cancer Center

Completed

Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Myelofibrosis/Myeloproliferative Disorder

Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Myelodysplastic/Myeloproliferative Diseases

United States
Case Comprehensive Cancer Center

Completed

Docetaxel,Carboplatin,Trastuzumab and Bevacizumab for Breast Cancer and Bone Marrow Micrometastases

Breast Cancer

United States
Case Comprehensive Cancer Center

Completed

Low-Residue Diet in Treating Diarrhea in Patients Receiving Pelvic Radiation Therapy.

Sarcoma | Cervical Cancer | Diarrhea | Prostate Cancer | Radiation Toxicity

United States
Case Comprehensive Cancer Center

Withdrawn

Culturally Tailored Decision Aid for Hispanic Patients Diagnosed With Prostate Cancer

Prostate Cancer
Case Comprehensive Cancer Center

Completed

A Sleep Intervention to Improve Outcomes Among Women at High Risk of Breast Cancer

Breast Cancer | Sleep

United States
Case Comprehensive Cancer Center

Completed

The Mediating Effects of Decentering on Self-Management of Stress and End of Life Planning

Stage IV Gastrointestinal Cancer | Advanced Gynecological Cancer

United States
Case Comprehensive Cancer Center

Completed

Enzalutamide in Patients With High-risk Prostate Cancer

Adenocarcinoma of the Prostate

United States

Clinical Trials Sponsored by Cancer Care Ontario

Sponsors and Collaborators

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