Clinical Trials Sponsored by Carlos III Health Institute

Total 502 results

Gerencia de Atención Primaria, Madrid
Instituto de Salud Carlos III

Completed

Effectiveness of a Chat Bot for Smoking Cessation: a Pragmatic Trial in Primary Care. (Dej@lo)

Tobacco Use Cessation

Spain
Gerencia de Atención Primaria, Madrid
Instituto de Salud Carlos III

Completed

The COMUNICARE Study: the Effectiveness of a Multimodal Intervention Based on Person-centered Communication (COMUNICARE)

Diabetes Mellitus, Type 2
Gerencia de Atención Primaria, Madrid
Instituto de Salud Carlos III

Completed

Oral/Intramuscular B12 to Treat Cobalamin Deficiency (OB12)

Vitamin B 12 Deficiency

Spain
Gerencia de Atención Primaria, Madrid
Instituto de Salud Carlos III

Completed

Auto-acupressure: Effectiveness for Diminishing Neck Pain of Benign Origin

Neck Pain

Spain
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III

Unknown

Hospital Without Dyspnea. Rationale and Design of a Multidisciplinary Intervention

Dyspnea

Spain
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III

Completed

Use of a Pressurized Face Mask for Preventing Respiratory Complications After Chest Surgery

Lung Resection

Spain
Fundació Sant Joan de Déu
Instituto de Salud Carlos III

Completed

A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity

Obesity
Asociacion Colaboracion Cochrane Iberoamericana
Instituto de Salud Carlos III; Ministry of Health, Spain

Completed

Clinical Trial for the Assessment of Delayed Antibiotic Treatment in Pediatric (DAP-Pediatrics) (DAP)

Rhinosinusitis | Acute Otitis Media | Acute Bronchitis | Pharyngotonsillitis

Spain
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III

Recruiting

Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2) (THYTECH2)

Systemic Inflammatory Response Syndrome

Spain
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III

Recruiting

Exercise Program for Colorectal Older Patients (ECOOL)

Colorectal Neoplasms | Aged

Spain
Hospital Clinico Universitario de Santiago
Instituto de Salud Carlos III

Completed

Exercise-based Cardiac Rehabilitation for the Prevention of Breast Cancer Chemotherapy-induced Cardiotoxicity (ONCORE)

Cardiotoxicity | Cardiac Rehabilitation

Spain
Spanish Breast Cancer Research Group
Instituto de Salud Carlos III

Completed

Retrospective Observational Study About Evolution of Patients With Breast Cancer in Hospitals From GEICAM Group (ALAMO-IV)

Invasive Breast Cancer Between 2002 and 2005

Spain
University of the Balearic Islands
Instituto de Salud Carlos III

Active, not recruiting

Effectiveness of a Nurse-led Personalized Telephone Intervention on Lifestyle Changes in Diabetes Prevention. (PREDIPHONE)

Prediabetic State

Spain
Hospital Universitario Ramon y Cajal
Instituto de Salud Carlos III

Active, not recruiting

Impact of a Personalized Multicomponent Exercise Program in Real Conditions Among Older Adults With HIV (MOVIhNG)

Quality of Life | Frailty | Body Composition | Physical Inactivity

Spain
Jordi Gol i Gurina Foundation
Instituto de Salud Carlos III

Completed

Colorectal Cancer Screening in Primary Care (COLO-ALERT)

Colorectal Neoplasms

Spain
Universidad Miguel Hernandez de Elche
Instituto de Salud Carlos III

Completed

Changes Induced by Breakfast Cereals Enriched With Omega-3 in the Lipidic Profile (cereals)

Overweight

Spain
Gerencia de Atención Primaria, Madrid
Instituto de Salud Carlos III

Completed

Effectiveness of a Structured Intervention to Reduce the Progression of Chronic Kidney (RENAP Study) (RENAP)

Renal Insufficiency Chronic

Spain
Gerencia de Atención Primaria, Albacete
Instituto de Salud Carlos III

Unknown

Effectiveness of a Combined Strategy to Improve Therapeutic Compliance and Degree of Control Among Patients With Hypercholesterolaemia (EFESCOM)

Hypercholesterolemia | Medication Adherence | Primary Health Care
Universidad Miguel Hernandez de Elche
Instituto de Salud Carlos III

Completed

Nutritional Intervention With Yogurt and Flaxseed in Women With Profiles Lipi (flaxseed)

Overweight

Spain
University of the Balearic Islands
Instituto de Salud Carlos III

Completed

Action of Essential Fatty Acids on the Expression of Antioxidant Genes and Athletic Performance

Exercise | Oxidative Stress | Athletic Performance | Training Season | Antioxidant Capabilities

Spain
Germans Trias i Pujol Hospital
Instituto de Salud Carlos III

Recruiting

Neuropsychological and Neuroimaging Evaluation of the Cognitive Impairment in Aortic Valve Replacement (ARTiCO) (ARTiCO)

Stroke | Cognitive Impairment | Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement | Surgical Treatment

Spain
Gerencia de Atención Primaria, Madrid
Instituto de Salud Carlos III

Active, not recruiting

Pain Education, Motivational Interviewing and Exercise in Chronic Neck Pain (COGMO)

Chronic Pain | Neck Pain

Spain
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III

Suspended

Clinical Trial at Neoadjuvant Peritoneal and Systemic Chemotherapy Plus HIPEC in Gastric Carcinomatosis (HIPEC)

Gastric Cancer | Peritoneal Carcinomatosis

Spain
Mikel Batllori
Instituto de Salud Carlos III

Completed

Comparison of Three Techniques for Ultrasound-guided Internal Jugular Cannulation (OISO-1)

Ultrasound-guided Internal Jugular Cannulation | Central Venous Access Complications

Spain
Fundació Sant Joan de Déu
Instituto de Salud Carlos III

Completed

Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery

Progressive Infantile Idiopathic Scoliosis

Spain
Gerencia de Atención Primaria, Albacete
Instituto de Salud Carlos III

Unknown

Prevention of Falls and Fractures in Old People by Administration of Calcium and Vitamin D. Randomized Clinical Trial (ANVITAD)

Fall | Fractures

Spain
Instituto de Salud Carlos III
UBS Optimus Foundation; Armauer Hansen Research Institute, Ethiopia

Completed

Visceral Leishmaniasis and Malnutrition in Amhara Regional State, Ethiopia (VL&MNEthio)

Malnutrition | Visceral Leishmaniasis
Fundacion Para La Investigacion Hospital La Fe
University of Valencia; Carlos III Health Institute

Completed

Prenatal Corticosteroids and Antioxidants in Preterm Infants (RESOX)

Oxidative Stress

Spain
Angel Chamorro, MD
Carlos III Health Institute

Completed

Efficacy Study of Combined Treatment With Uric Acid and rtPA in Acute Ischemic Stroke (Urico-Ictus)

Acute Ischemic Stroke

Spain
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III

Unknown

"Mindfulness vs Psychoeducation in Bipolar Disorder" (BI-MIND)

Depressive Symptoms | Bipolar

Spain
Hospital Miguel Servet
Fondo de Investigacion Sanitaria; Carlos III Health Institute; Aragon Health... and other collaborators

Completed

Role of Positron Emission Tomography in the Evaluation of Response to Sorafenib in Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

Spain
Hospital Universitario Fundación Alcorcón
Instituto de Salud Carlos III; European Union

Recruiting

Multimedia Animations to Support Therapeutic Exercise for Rotator Cuff Shoulder Pain

Rotator Cuff Tendinitis | Rotator Cuff Impingement Syndrome | Rotator Cuff Related Shoulder Pain

Spain
Cristina García-Vivar
Instituto de Salud Carlos III

Not yet recruiting

Web-based Intervention for Long-term Breast Cancer Survivors (CUMACA-M)

Long-term Effects Secondary to Cancer Therapy in Adults | Long-term Effects of Cancer Treatment
Instituto de Salud Carlos III
Fondo de Investigacion Sanitaria; Osakidetza; MurciaSalud

Completed

Efficacy of the Otago Exercise Program Delivered as Group Training Versus Individually Tailored Training

Age Problem

Spain
Albert Saiz
Instituto de Salud Carlos III

Terminated

Mesenchymal Stem Cell Transplantation in MS (CMM-EM)

Multiple Sclerosis

Spain
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III

Not yet recruiting

Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins (PREVESTATGx)

Cardiovascular Diseases | Dyslipidemias | Statin Adverse Reaction | Pharmacogenic Myopathy

Spain
Hospital Universitario Araba
Instituto de Salud Carlos III; Ibermática/i3B; Bioraba

Completed

Sleep Thermography for Diagnosis of Obstructive Sleep Apnea (TERMOAPNEA) (TERMOAPNEA)

Obstructive Sleep Apnea (OSA)

Spain
University Hospital Virgen de las Nieves
Instituto de Salud Carlos III

Completed

eSET Plus Single Embryo Cryotransfer vs Double Embryo Transfer (eSET)

Infertility | Pregnancy, Multiple

Spain
Hospital Universitario Reina Sofia de Cordoba
Instituto de Salud Carlos III

Completed

Tobacco Intensive Motivational and Estimate Risk

Smoking Cessation | COPD | Severe Mental Disorder

Spain
Hospital Clinic of Barcelona
Instituto de Salud Carlos III; European Union

Completed

Prevention of Left Ventricular Dysfunction During Chemotherapy (OVERCOME)

Lymphoma | Acute Myeloid Leukemia | Multiple Myeloma | Lymphoid Neoplasm | Autologous Hematopoietic Stem Cell Transplantation | Precursor-cell Lymphoblastic Leukemia-Lymphoma

Spain
Dr. Marta Alda
Carlos III Health Institute; Instituto Aragones de Ciencias de la Salud

Unknown

Efficacy of Acceptance and Commitment Therapy (ACT) in Group in Fibromyalgia (ACTGROUP)

Fibromyalgia

Spain
University Hospital Virgen de las Nieves
Instituto de Salud Carlos III

Unknown

Immunogenicity and Safety of a 9-valent Human Papillomavirus Vaccine in HIV-positive Women (9-VPH-MVIH)

HIV Infections | HPV Infection

Spain
Hospital Universitario Getafe
Instituto de Salud Carlos III; SALUDNOVA SOLUTION S.L

Completed

mHealth to Early Detect Exacerbation for Older People With Heart Failure (mobileHF)

Heart Failure
José Ortiz
Instituto de Salud Carlos III

Completed

Pilot Safety Study of Coronary CTA for the Diagnosis of Acute Coronary Syndrome in the Emergency Room

Myocardial Infarction | Coronary Artery Disease | Acute Coronary Syndrome | Cardiac Death

Spain
Consorcio Centro de Investigación Biomédica en...
Carlos III Health Institute; Barcelona Supercomputing Center

Completed

One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19

Respiratory Failure | Acute Respiratory Distress Syndrome | Severe Pneumonia

Spain
University Hospital Inselspital, Berne
Carlos III Health Institute; Michael J. Fox Foundation for Parkinson's Research

Recruiting

International Validation of Two Non-motor Scales in PD (NFS and SPARK)

Parkinson's Disease | Non-motor Symptoms

Spain, Germany, France, Greece, Romania, Switzerland, United Kingdom
Hospital Miguel Servet
Centro Nacional de Investigaciones Oncologicas CARLOS III; Aragon Institute...

Unknown

Circulating Exosomes As Potential Prognostic And Predictive Biomarkers In Advanced Gastric Cancer Patients ("EXO-PPP Study") (EXO-PPP)

Gastric Cancer

Spain
José María Piulats Rodríguez
Instituto de Salud Carlos III

Not yet recruiting

Phase I/II Study of AloCelyvir in Patients With Metastatic Uveal Melanoma (PULSE-UM)

Uveal Melanoma, Metastatic

Spain
Carlos III Health Institute
Merck Sharp & Dohme LLC; Red Temática de Investigación Cooperativa en Sida

Unknown

Pregnancy in Women With HIV Infection

HIV Infections | Pregnancy Related
Hospital Universitari de Bellvitge
Hospital Clinic of Barcelona; Carlos III Health Institute; Public Health Agency...

Recruiting

The Impact of Air Pollution on the Consumption of Antimicrobials in the General Population (ONAIR)

Air Pollution | Community-acquired Pneumonia | Drug Resistance, Microbial

Spain

Clinical Trials Sponsored by Carlos III Health Institute

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Brazil

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Rare Diseases

Drug Interventions

Dietary Supplements

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