Clinical Trials Sponsored by Centre Georges Francois Leclerc

Total 81 results

Centre Georges Francois Leclerc

Not yet recruiting

Clinical Trial Evaluating the Safety and Efficacy of Chemoimmunotherapy Plus Short Course of Mek Inhibitor in First Line of Treatment of Metastatic Non Squamous Non Small Cell Lung Adenocarcinoma With PDL1 < 50 %. (IMMUNOMEK)

Non-Small Cell Lung Cancer
Centre Georges Francois Leclerc

Recruiting

Influence of Food Preferences on the Occurrence of Undernutrition in Treated Patients for Bronchopulmonary Carcinoma Non-small Cell Stage IV (ONCOGOU)

Non-small Cell Bronchopulmonary Carcinoma at Stage IV and Benefiting From First-line Treatment According to Current French Recommendations

France
Centre Georges Francois Leclerc

Recruiting

Evaluation and Modeling of the Effect of G-CSF on the Evolution of Polynuclear Neutrophils During Dense Dose Epirubicin-Cyclophosphamide Regeneration (EMEG-ECDD)

Localized Breast Cancer

France
Centre Georges Francois Leclerc

Recruiting

Assessment of Health Related Quality of Life in Women Who Underwent Breast Reconstruction After Radical Surgery (RMQOL)

Breast Cancer

France
Centre Georges Francois Leclerc

Recruiting

FCH vs FDG PET/CT in Detection of Lesions in Patients With Multiple Myeloma (MIM) (MIM)

Multiple Myeloma

France
Centre Georges Francois Leclerc

Recruiting

Health-Related Quality of Life Coupled With Therapeutic Information on Compliance to Endocrine Therapy in Breast Cancer (COMPLIANCE)

Breast Cancer

France
Centre Georges Francois Leclerc

Recruiting

Neoadjuvant Database (NEOADJ)

Neoadjuvant Treatment in Breast Cancer

France
Centre Georges Francois Leclerc

Recruiting

Thyroid Cancer Database

Patients With a Thyroid Tumor Who Received Radioactive Iodine Treatment

France
Centre Georges Francois Leclerc

Recruiting

Study of Exosomes in Monitoring Patients With Sarcoma (EXOSARC) (EXOSARC)

Sarcoma

France
Centre Georges Francois Leclerc

Recruiting

Study Evaluating the Efficacy and the Tolerance of Pelvic-prostatic Hypo-fractionated Radiotherapy Followed by Boost in Patients With Prostate Adenocarcinoma Adverse Intermediate Risk or High Localized Risk (SHORT)

To Evaluate the Rate of Digestive and Urinary Toxicity

France
Centre Georges Francois Leclerc

Terminated

Evaluation of the Dose Received by the Prostate With in Vivo Dosimetry in Patients Treated With Daily IGRT Associated With IMRT Using Two Repositioning Techniques for Localized Prostate Cancer (PROSTRACK)

Prostate Cancer

France
Centre Georges Francois Leclerc

Active, not recruiting

In Situ Immune Parameters and Their Prognostic Role on the Survival of Patients With Glioblastoma (IMMUNOGLIO)

Glioblastoma

France, Italy
Centre Georges Francois Leclerc

Active, not recruiting

Evaluation of the Impact of a Pharmaceutical Interview on the Adherence to Hormonotherapy in Women With Breast Cancer (HORMONOVILLE)

Breast Cancer

France
Centre Georges Francois Leclerc

Completed

Evaluation of GEMCITEST in Patients With Pancreatic Cancer and Treated by Chemotherapy (GEMCIPANC)

Pancreatic Cancer

France
Centre Georges Francois Leclerc

Completed

Predictive Study of Radiation Induced Sarcoma (SARI)

Radiation Induced Sarcoma

France
Centre Georges Francois Leclerc

Not yet recruiting

Evaluation of the Concordance Between Pre-therapy Dosimetry Performed From 68Ga-PSMA-11 Dynamic PET and Post-treatment Dosimetry of 177Lu-PSMA-617 Vectorized Internal Radiotherapy in Patients With Metastatic Prostate Cancer Resistant to Hormonal Castration. (GaLuPro)

Patients With Metastatic Castration-resistant Prostate Cancer
Centre Georges Francois Leclerc

Recruiting

Trial Evaluating the Efficacy and the Safety of FOLFIRINOX3 Treatment in Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer in First Line of Chemotherapy (FOLFIRINOX3 P)

Metastatic Pancreatic Cancer

France
Centre Georges Francois Leclerc

Recruiting

Impact of Non-magnetic Screen Respiratory Self-guidance During MRI-guided Radiotherapy Sessions for Mobile Lesions (RespEcran)

Patient With Radiotherapy (Linac MRI) | Mobile Cancerous Lesion

France
Centre Georges Francois Leclerc

Recruiting

Randomized Study Versus Placebo for the Prevention of Neurotoxicity Induced by Weekly PACLITAXEL (NEUROTAX)

Breast Cancer

France
Centre Georges Francois Leclerc

Recruiting

Evaluation of Efficacy of Trifluridine/Tipiracil Plus an Anti-IL-1α True Human Antibody Versus Trifluridine/Tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine (TASKIN)

Metastatic Colorectal Cancer

France
Centre Georges Francois Leclerc

Active, not recruiting

Evaluation of the Efficacy and the Safety of a Stereotaxic Prostatic Radiotherapy Delivered With Linac MRI, in Patients With Prostate Adenocarcinoma (STEREO-RML)

Adenocarcinoma of the Prostate

France
Centre Georges Francois Leclerc

Active, not recruiting

Adaptative MR-Guided Stereotactic Body Radiotherapy of Liver Tumors (RASTAF)

Radiotherapy

France
Centre Georges Francois Leclerc

Active, not recruiting

Immuno Monitoring in Patient With Epithelial Ovarian Cancer Eligible to PARP Inhibitors (IMMUNOPARP)

Ovarian Cancer

France
Centre Georges Francois Leclerc

Completed

Study Evaluating the Influence of LV5FU2 Bevacizumab Plus Anakinra Association on Metastatic Colorectal Cancer (IRAFU)

Metastatic Colorectal Cancer

France
Centre Georges Francois Leclerc

Active, not recruiting

Relevance of T Lymphocytes Tumor Infiltrates CD8 and Foxp3 as Immune Prognostic Biomarker in Breast Cancer Treated by Neo Adjuvant Chemotherapy (PRIMUNEO)

Breast Cancer

France
Centre Georges Francois Leclerc

Active, not recruiting

Study Evaluating the Efficacy of Radiotherapy With SIB-IMRT, Associated With Temozolomide in Glioblastomas (Glio-SIB-Up)

Glioblastoma, Adult

France
Centre Georges Francois Leclerc

Terminated

Multimetabolic 18F-Fluorodeoxyglucose (FDG) and 18F-Fluorocholine (FCH) Positron Emission Tomography (PET) as an Early Predictive Factor of Overall Survival in Patients With Advanced Hepatocellular Carcinoma Treated With Sorafenib (PREMETHEP)

Carcinoma, Hepatocellular

France
Centre Georges Francois Leclerc

Completed

Mechanisms of Anti COVID-19 Humoral and Cellular Immune Response After Vaccination in a Sample of Patients and Salaried Staff From a French Anti-cancer Center (CANSEROVAX)

Cancer

France
Centre Georges Francois Leclerc

Completed

Pemetrexed in Maintenance in Patients With Impaired Renal Function, 2 Dose Calculation Strategies (PKAPIR)

Non-small Cell Lung Cancer

France
Centre Georges Francois Leclerc

Completed

Study of the Specific Seroprevalence of SARS-CoV-2 in a Sample of Patients and Salaried Staff From a French Anti-cancer Center at the End of the Containment Period of the SARS-CoV-2 Pandemic (canSEROcov)

Cancer

France
Centre Georges Francois Leclerc

Completed

Preoperative Chemo-radiation With IG-IMRT Dose Escalation for Locally Advanced Rectal Cancers (RADICAL)

Advanced Rectal Cancers

France
Centre Georges Francois Leclerc

Completed

A Positron Emission Tomography (PET) Imaging Agent [18F]-ODS2004436 as a Marker of EGFR Mutation in Subjects With NSCLC (IMKRUN 2)

Carcinoma, Non-Small-Cell Lung

France
Centre Georges Francois Leclerc

Completed

What Benefit of a Full Analysis of Exome? Routine Care Study in Patients With Solid Tumors (EXOMA)

Carcinoma

France
Centre Georges Francois Leclerc

Unknown

Metastatic Colorectal Cancer Database

Metastatic Colorectal Cancer

France
Centre Georges Francois Leclerc

Completed

Study of Microcirculatory Effects of Bevacizumab in Patients Treated for Metastatic Colon Cancer or Glioblastoma (BEVACAPI)

Glioblastoma | Metastatic Colorectal Cancer | Bevacizumab | Capillaroscopy

France
Centre Georges Francois Leclerc

Completed

Spectro-IRM and Evaluation Response to Prostatic Radiotherapy (ERIS)

Prostate Cancer

France
Centre Georges Francois Leclerc

Not yet recruiting

Use of an Ultra-rapid BRCA1/2 Status Screening Test in Theranostic Indication: Performance and Interest for Patients and Practitioners (TURBO)

Breast Cancer
Centre Georges Francois Leclerc

Recruiting

Functional Evaluation After Breast Reconstruction With a Minimally Invasive Latissimus Dorsi Flap Following Radical Surgery for Breast Cancer. (BREAST)

Breast Cancer

France
Centre Georges Francois Leclerc

Recruiting

Study Evaluating the Safety and the Efficacy of Combination of Atezolizumab, Tiragolumab and and Stereotactic Body Radiation Therapy in Patients With Oligometastatic Multiorgan (IMMUNOs-SBRT) (IMMUNOs-SBRT)

Metastatic Renal Cell Carcinoma | Metastatic Non Small Cell Lung Cancer | Metastatic Head and Neck Cancer | Metastatic Bladder Cancer

France
Centre Georges Francois Leclerc

Recruiting

Value of Information of Secondary dAta in ONCOGEnetics (VISAGE-ONCO)

Cancer | Genetic Predisposition | Secondary Fundings

France
Centre Georges Francois Leclerc

Recruiting

Modifications in Retinal Microvascularization With Targeted Anti-angiogenic Therapy in Colorectal Cancer (VOCANGIO)

Colorectal Cancer

France
Centre Georges Francois Leclerc

Recruiting

Immunomonitoring of Breast Cancer Patients During Systemic Treatment (IMMUNE CAPTURE)

Breast Cancer

France
Centre Georges Francois Leclerc

Recruiting

Exome Analysis (Complexe vs Simple) to Help the Therapeutic Decision for the Precision Medicine (EXOMA2)

Cancer

France
Centre Georges Francois Leclerc

Recruiting

EXOME Analysis Position in the Strategy of Genetic Predisposition Factors Identification in Early-onset Cancer (EX²TRICAN)

Cancer | Genetic Predisposition

France
Centre Georges Francois Leclerc

Recruiting

Evaluation of the Accuracy of Percutaneous Biopsy by Vacuum-assisted Biopsy (VAB) to Assess Pathological Complete Response in Patients With Clinical and Radiological Complete Response After Neoadjuvant Chemotherapy (NeoVAB) (NeoVAB)

Vacuum-assisted Biopsy

France
Centre Georges Francois Leclerc

Recruiting

Evaluation of the Unconformity of the Hormonal Status of Metastatic Lesions During a First Relapse of Breast Cancer Initially Expressing Estrogen Receptors: a Pilot Study on the Interest of PET With FES (EstroTEPCompar)

FES TEP in Detection of Estrogen Receptors

France
Centre Georges Francois Leclerc

Active, not recruiting

Study Evaluating the Utility of 18F-FDG PET in Assessing Early Response to Neoadjuvant Chemotherapy in Patients With Mammary Gland Cancer (TREN)

FDG PET

France
Centre Georges Francois Leclerc

Completed

Validation of a Genetic Signature to Predict the Development of Sarcomas (PREDISARC)

Genetic Signature in Development of Sarcomas

France
Centre Georges Francois Leclerc

Active, not recruiting

Evaluation of the Efficacy and the Safety of FOLFIRINOX3 Bevacizumab Treatment in Patients With Colorectal Cancer (FOLFIRINOX 3) (FOLFIRINOX3)

Colorectal Cancer

France
Centre Georges Francois Leclerc

Terminated

Optimizing the Management of Patients With Oral Therapy (IPAC)

Kidney Cancer | Breast Cancer

France

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