Clinical Trials Sponsored by Children's Heart Center

Total 4485 results

Children's Heart Center
Zone Laboratories, Inc.

Terminated

Safety & Efficacy of Omega-3 Fish Oil in Overweight Children & Adolescents

Obesity | Overweight

United States
Boston Children's Hospital
American Heart Association; The Children's Heart Foundation

Terminated

Predicting Arrhythmogenic Risk in Congenital Heart Patients: the PRECISION Study

Congenital Heart Disease | Arrhythmia in Children

United States
Children's Hospital Medical Center, Cincinnati
American Heart Association

Completed

TRPV2 Agonists in the Fontan Circulation

Fontan

United States
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute

Recruiting

Accelerating Delivery of rheUmatic Heart Disease Preventive iNterventions in Northern Uganda (ADUNU)

Rheumatic Heart Disease

Uganda
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute

Recruiting

GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial

Rheumatic Heart Disease

Uganda
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute

Completed

Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health System (ADD-RHD 2B)

Rheumatic Heart Disease

Uganda
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute

Completed

Case Management and Peer Support Groups for Prophylaxis Adherence in Rheumatic Heart Disease (CAMPS)

Rheumatic Heart Disease

Uganda
Children's Hospital Medical Center, Cincinnati
Children's National Research Institute; Uganda Heart Institute

Active, not recruiting

Rheumatic Heart Disease Community Streptococcal Treatment Program "RESET"

Rheumatic Heart Disease

Uganda
Boston Children's Hospital
Evan's Heart Fund; Mend a Heart Foundation; Matthew Hearts of Hope Foundation

Completed

Fontan Imaging Biomarkers (FIB) Study (FIB)

Congenital Heart Disease | Single-ventricle

United States
Providence Medical Research Center
Providence Sacred Heart Medical Center & Children's Hospital

Terminated

Celiac Disease and Unexplained Iron Deficiency in a Primary Care Setting

Celiac Disease | Iron Deficiency | Iron Malabsorption

United States
Children's Cancer Group, China
Shanghai Children's Medical Center

Recruiting

CCCG-HD-2018 for Children and Adolescents With Newly Diagnosed Hodgkin Lymphoma

Hodgkin Lymphoma

China
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute; Murdoch Children's Research Institute, Melbourne Australia

Active, not recruiting

A Long-term Follow up Study for Patients Who Participated in the GOAL Trial (GOAL-Post)

Rheumatic Heart Disease

Uganda
Nationwide Children's Hospital
American Heart Association

Completed

CTICU Pacifier Activated Music Player and Mother's Voice

Heart Defects, Congenital

United States
Seattle Children's Hospital
American Heart Association

Completed

Preschoolers Active at Child Care (PACT) (PACT)

Physical Activity
Nationwide Children's Hospital
American Heart Association

Completed

Echocardiographic Assessment of Function During ECMO Support

Extracorporeal Membrane Oxygenation Complication | Cardiac Failure

United States
Boston Children's Hospital
Thrasher Research Fund; The Children's Heart Foundation

Completed

Improving Neurodevelopment in Adolescents With Congenital Heart Disease

Executive Function | Congenital Heart Disease | Neurodevelopment | Working Memory Training | Infant Open-heart Surgery

United States
Boston Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI); Children's Hospital Medical...

Completed

Bone Marrow Cell Gene Transfer in Individuals With Fanconi Anemia

Fanconi Anemia

United States
Heart Center Bogenhausen

Unknown

MRI Perfusion Imaging at 3Tx Compared to Invasive FFR Measurements (Vision MRT)

Myocardial Ischemia | MRI | Perfusion Imaging | Myocardial Fractional Flow Reserve

Germany
Murdoch Childrens Research Institute
Royal Children's Hospital; Peter MacCallum Cancer Centre, Australia

Not yet recruiting

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Arteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditions

Australia
Tehran Heart Center

Completed

Evaluation of Long-term Coronary Stenting Outcomes in Diabetic Patients With or Without Optimal Glycemic Control

Coronary Artery Disease | Diabetes

Iran, Islamic Republic of
German Heart Center

Unknown

Comparison of Aprotinin and Tranexamic Acid in Routine Cardiac Surgery

Coronary Artery Bypass Graft Surgery | Aortic Valve Replacement | Bleeding and Cardiac Surgery | Allogeneic Blood Transfusion

Germany
Shriners Hospitals for Children
Children's Hospital Medical Center, Cincinnati

Completed

Differential Effects of Zolpidem Versus Ramelteon in Burned Children (Sleep3)

Burns | Sleep

United States
Children's Hospital of Philadelphia
Patient-Centered Outcomes Research Institute; Children's Hospital Medical Center... and other collaborators

Active, not recruiting

Community Health Workers and mHealth for Sickle Cell Disease Care

Sickle Cell Disease

United States
Connecticut Children's Medical Center
The Hospital for Sick Children

Recruiting

ATOMIC Mobile App to Increase Physical Activity (PA) Levels in Survivors of Childhood Cancer

Pediatric Cancer

United States
Shriners Hospitals for Children
Children's Hospital Medical Center, Cincinnati

Completed

The Effect of Healing Touch on Sleep (Sleep7)

Elective Reconstructive Surgery Population

United States
Shriners Hospitals for Children
Children's Hospital Medical Center, Cincinnati

Completed

Circadian Rhythm of Melatonin in Burns (Sleep4)

Burns | Sleep

United States
EpicentRx, Inc.
Texas Children's Cancer Center

Active, not recruiting

RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors (PIRATE)

Unspecified Childhood Solid Tumor, Protocol Specific | Central Nervous System Neoplasms | Brain Tumor, Recurrent | Brain Tumor, Pediatric

United States
Children's Healthcare of Atlanta
The Hospital for Sick Children; Children's Hospital Medical Center, Cincinnati and other collaborators

Completed

Pediatric Acute Kidney Injury in COVID-19 (SPARC-1)

Acute Kidney Injury | COVID

United States, Canada, Spain, Israel, Japan, Serbia, United Kingdom
The Hospital for Sick Children
Labatt Family Heart Centre

Recruiting

Prospective Observational Cohort Study of Fetal Atrial Flutter & Supraventricular Tachycardia (FAST Registry)

Atrial Flutter | Tachycardia, Supraventricular | Tachycardia, Atrioventricular Nodal Reentry | Tachycardia Atrial | Tachycardia, Reciprocating | Tachycardia, Paroxysmal | Fetal Hydrops | Tachycardia, Atrial Ectopic

United States, Hong Kong, Canada, Netherlands, Sweden, Australia, Brazil, Finland, France, Russian Federation, Spain, Czechia, Switzerland, United Kingdom
Children's Hospital of Philadelphia
The Hospital for Sick Children; Children's Hospital Medical Center, Cincinnati

Completed

More Frequent In-Center Hemodialysis in Pediatric End Stage Renal Disease

Hemodialysis | Pediatric End Stage Renal Disease

United States, Canada
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Realizing Effectiveness Across Continents With Hydroxyurea (REACH)

Children | Sickle Cell Disease

Congo, The Democratic Republic of the, Angola, Kenya, Uganda
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRI

Cystic Fibrosis

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100

Fanconi Anemia

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Adolescent Controlled Text Messaging to Improve Asthma Medication Adherence in Primary Care (ACT Me)

Persistent Asthma

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Research Study for Children About Heart Changes and Obstructive Sleep Apnea (OSA)

Obstructive Sleep Apnea

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Dexamethasone to Treat Acute Chest Syndrome in People With Sickle Cell Disease

Anemia, Sickle Cell

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

CV Disease in Adolescents With Type 2 Diabetes

Heart Diseases | Cardiovascular Diseases | Obesity | Diabetes Mellitus

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Airway Clearance Therapy on Hyperpolarized 129Xenon and MRI

Cystic Fibrosis

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Environmental Exposures, Genetics, and Exhaled Nitric Oxide in Pediatric Asthma

Asthma

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Genomic Basis of Neurodevelopmental and Brain Outcomes in Congenital Heart Disease (CHD Brain and Genes)

Heart Disease Congenital

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparing Chest Images From MRI to CT in Patients With Cystic Fibrosis (CF)

Cystic Fibrosis

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Role of Placenta Growth Factor in Sickle Acute Chest Syndrome

Anemia, Sickle Cell

United States
National Heart, Lung, and Blood Institute (NHLBI)
Children's Hospital Medical Center, Cincinnati

Completed

Blood Cell Collection for Future Use in Individuals With Fanconi Anemia

Fanconi Anemia

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Congenital Heart Disease GEnetic NEtwork Study (CHD GENES) (CHD GENES)

Congenital Heart Defects

United States, United Kingdom
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome (DYMOSA)

Obstructive Sleep Apnea | Down Syndrome

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Using MRI to Observe Lung Changes in Infants With CF Compared to Infants Without CF (MRIinfantCF)

Cystic Fibrosis

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mechanisms Mediating Cardiovascular Disease in Children With Obstructive Sleep Apnea

Heart Diseases | Cardiovascular Diseases | Sleep Apnea Syndromes | Lung Diseases | Hypertension
Medinet Heart Centre

Unknown

Remote Ischemic Conditioning to Attenuate Myocardial Death and Improve Operative Outcome. (RICARDO)

Coronary Artery Bypass | Ischemic Postconditioning | Myocardial Reperfusion Injur | Ischemic Preconditioning, Myocardial

Poland
Medinet Heart Centre

Unknown

Effect of Preoperative Aspirin in Patients Undergoing Off-pump Coronary Artery Bypass Grafting

Coronary Artery Disease | Aspirin

Poland
Maritime Heart Centre

Completed

Randomized Clinical Trial Comparing Coronary Bypass Grafting With or Without Cardiopulmonary Bypass

Ischemic Heart Disease

Canada

Clinical Trials Sponsored by Children's Heart Center

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