Clinical Trials Sponsored by DeveloGen AG, Germany

Total 73 results

Aspireo Pharmaceuticals Limited
DeveloGen AG, Germany

Completed

Single Ascending Dose Tolerability Study of DG3173

Healthy
Charite University, Berlin, Germany
Physiomed Elektromedizin AG Germany

Completed

The Effect of Physical Therapy on Raynaud's Phenomenon Secondary to Systemic Sclerosis

Systemic Sclerosis | Raynaud's Phenomenon

Germany
AstraZeneca
iOMEDICO AG, Freiburg, Germany

Completed

PANORAMA - Real World Molecular Testing, Treatment Patterns, and Clinical Outcomes EGFR Mutation-Positive NSCLC (PANORAMA)

Carcinoma, Non-Small-Cell Lung

Germany
4SC AG
Merck KGaA, Darmstadt, Germany

Withdrawn

Domatinostat in Combination With Avelumab in Patients With Treatment-naïve Metastatic Merkel Cell Carcinoma (MERKLIN 1)

Merkel Cell Carcinoma
Charite University, Berlin, Germany
Brahms AG

Completed

Impact of Therapy Optimization on the Level of Biomarkers in Patients With Decompensated Heart Failure (MOLITOR)

Decompensated Heart Failure

Germany
Charite University, Berlin, Germany
Aesculap AG

Unknown

Joint Line Reconstruction in Navigated Total Knee Arthroplasty Revision (NavRevKnie)

Revision Total Knee Arthroplasty Because of | Loosening | Instability | Impingement | or Other Reasons Accepted as Indications for TKA Exchange. | The Focus is to Determine the Precision of Joint Line Restoration in Navigated vs. Conventional Revision Total Knee Arthroplasty

Germany
Charite University, Berlin, Germany
Stimit AG

Completed

Electromagnetic Stimulation of the Phrenic Nerve of Intubated Patients With Obesity (STIMIT-IA)

Muscle Weakness | General Anaesthesia

Germany
Charite University, Berlin, Germany
Stimit AG

Terminated

Electromagnetic Stimulation of the Phrenic Nerve in Critically Ill Mechanically Ventilated Patients (STIMIT-II) (STIMIT-II)

Critical Illness | Muscle Weakness | Mechanical Ventilation Complication

Germany
Charite University, Berlin, Germany
Stimit AG

Completed

Electromagnetic Stimulation of the Phrenic Nerve of Intubated Patients (STIMIT-I)

Muscle Weakness | General Anaesthesia

Germany
University of Göttingen
Curetis AG, Holzgerlingen, Germany

Completed

Fast Identification of Pathogen in the Setting of Pneumonia Using Multiplex PCR

Pneumonia | Acute Lower Respiratory Tract Infection

Germany
B.Braun Avitum AG
Labor Limbach, Heidelberg, Germany; Clin-Sol, Würzburg, Germany

Completed

Determination of in Vivo Ultrafiltration Coefficient (KUF) in Patients With Chronic Kidney Disease (CKD)

Kidney Disease

Germany
German Cancer Research Center
Charite University, Berlin, Germany; Roche Pharma AG; Johannes Gutenberg University... and other collaborators

Recruiting

A MultIceNTER Phase I Peptide VaCcine Trial for the Treatment of H3-Mutated Gliomas (INTERCEPT-H3)

Newly Diagnosed H3-mutated Glioma

Germany
Institut fur Klinische Forschung, Germany
Weleda AG

Terminated

MUltiple Sclerosis and Extract of Cannabis (MUSEC) Study (MUSEC)

Muscle Spasticity

United Kingdom
Charite University, Berlin, Germany
Medical Park AG

Completed

External Lid Loading for the Temporary Treatment of the Paresis of the M. Orbicularis Oculi: a Clinical Note

Incomplete Closure of Lid | Parotis Tumor | m. Orbicularis Oculi Paresis

Germany
University Medicine Greifswald
Bauerfeind AG, Zeulenroda, Germany

Completed

The Influence of Compression Stockings on Skin's Barrier Function at Patients With Chronic Venous Disease

Venous Insufficiency

Germany
German Breast Group
Roche Pharma AG

Recruiting

Neoadjuvant Endocrine Therapy +/- the PI3K Inhibitor Inavolisib in HER2+, HR+, PIK3CA Mutant Early Breast Cancer (GeparPiPPa)

HER2-positive Breast Cancer

Germany
Charite University, Berlin, Germany
Sanofi; Roche Pharma AG

Unknown

Study to Evaluate Safety and Efficacy of Perioperative Chemotherapy With Docetaxel, Cisplatin and Capecitabine (DCX) in Patients With Gastro-esophageal Cancer (DCXAIOCHARITE)

Gastric Cancer | Esophageal Cancer

Germany
B. Braun Melsungen AG
Charite University, Berlin, Germany

Completed

Coroflex ISAR 2000 Extended Registry (ISAR2000 Extended)

Coronary Artery Disease (CAD)

Germany, Spain, Malaysia
B. Braun Melsungen AG
Charite University, Berlin, Germany

Completed

Coroflex ISAR 2000 Registry (ISAR2000)

Coronary Artery Disease (CAD)

Germany, Spain, Malaysia
West German Study Group
Roche Pharma AG

Active, not recruiting

A Prospective, Randomized Multicenter, Open-label Comparison of Preoperative Trastuzumab Emtansine (T-DM1) With or Without Standard Endocrine Therapy vs. Trastuzumab With Standard Endocrine Therapy Given for Twelve Weeks in Patients With Operable HER2+/HR+ Breast Cancer Within the ADAPT Protocol. (ADAPT; T-DM1)

Breast Cancer

Germany
West German Study Group
Roche Pharma AG

Recruiting

A Prospective, Randomized Multicenter, Open-label Comparison of Preoperative Combination of Trastuzumab and Pertuzumab With or Without Concurrent Taxane Chemotherapy Given for Twelve Weeks in Patients With Operable HER2+/HR- Breast Cancer Within the ADAPT Protocol (ADAPT)

Breast Cancer

Germany
Center for Epidemiology and Health Research, Germany
Ava AG

Completed

TRACY - Track My Cycle (TRACY)

Fertility Monitor | Cycle Tracking

Germany
Karoline Krause
Roche Pharma AG

Completed

Tocilizumab in Patients With Schnitzler's Syndrome (TOCISCH)

Schnitzler's Syndrome

Germany
Friedemann Paul
Roche Pharma AG

Active, not recruiting

Sensitivity of Motor Assessment in MS - a Prospective Cohort Study (MOTOSENS)

Multiple Sclerosis, Chronic Progressive | Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive

Germany
German Breast Group
Roche Pharma AG; Celgene Corporation

Completed

Nanoparticle-based Paclitaxel vs Solvent-based Paclitaxel as Part of Neoadjuvant Chemotherapy for Early Breast Cancer (GeparSepto) (GeparSepto)

Inflammatory Breast Cancer | HER-2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III | Inflammatory Breast Cancer Stage IV

Germany
West German Study Group
Sanofi; Roche Pharma AG

Terminated

Imaging for Response Assessment of Neoadjuvant Chemotherapy in Primary Breast Cancer (GALADON)

Breast Cancer

Germany
Balgrist University Hospital
Industry (Schülke & Mayr AG, Switzerland and Germany)

Recruiting

General Decolonization With Octenisan® Set Before Elective Orthopedic Surgery (BALGDEC)

Elective Surgery | High Risk | Prevention of Surgical Site Infections | Randomized-controlled Trial

Switzerland
ProteoSys AG
Charite University, Berlin, Germany; Medical University Innsbruck; University... and other collaborators

Unknown

Annexin A3 (ANXA3) as Protein-Based Marker for Non-Invasive Molecular Diagnostics of Prostate Carcinoma

Benign Prostatic Hyperplasia | Prostate Cancer | Prostatic Intraepithelial Neoplasia
Drug Commission of the German Medical Association
Madaus AG

Terminated

Cholesterol-Lowering Effects of Policosanol

Hypercholesterolemia | Combined Hyperlipidemia
University of Giessen
Strathmann AG&Co, Hamburg, Germany; Cernelle, Ängelholm, Sweden

Completed

Efficacy Study of a Standardized Pollen Extract Preparation (Cernilton) to Treat Inflammatory Chronic Prostatitis-Chronic Pelvic Pain Syndrome (CP-CPPS)

Chronic Prostatitis | Chronic Pelvic Pain Syndrome

Germany
Royal Marsden NHS Foundation Trust
Merck KGaA, Darmstadt, Germany; 4SC AG

Unknown

Epigenetic Modulation of the immunE Response in GastrointEstinal Cancers (EMERGE) (EMERGE)

Cancer | GI Cancer

United Kingdom
Gaia AG
Charite University, Berlin, Germany; Universitätsklinikum Schleswig-Holstein...

Recruiting

Effectiveness of a Digital Health Application for Primary Hypertension (Liebria)

Hypertension

Germany
Christoph Königs
Roche Pharma AG; Chugai Pharma Germany GmbH

Recruiting

Dynamics of the Anti-factor VIII Antibody Signature During Treatment With Emicizumab (NAVIGATE)

Severe Hemophilia A | Severe Hemophilia A With Inhibitor | Severe Hemophilia A Without Inhibitor

Germany
Center for Epidemiology and Health Research, Germany
Abbott Products Operations AG

Terminated

Maternal and Newborn Safety Profile of Progestogens in EARLY Pregnancy (PEARLY)

Early Pregnancy Bleeding | Recurrent Pregnancy Loss

Germany
Bonn Education Association for Dietetics r.A.,...
FomMed HealthCare AG

Completed

Effect of Weight Management Programs on Cardiometabolic Risk Profile in Overweight Women (FM-01)

Overweight and Obesity | Dyslipoproteinemia
aap Implantate AG
German Federal Ministry of Education and Research

Recruiting

LOQTEQ® Antibacterial Pre-Market Study

Surgical Site Infection | Fractures, Closed | Fractures, Open | Fracture of Fibula

Germany
West German Center of Diabetes and Health
HMM Holding AG

Completed

TeleLifestyleCoaching for Weight Loss (FitMeFit)

Overweight

Germany
West German Center of Diabetes and Health
gbo Medizintechnik AG

Completed

HTEMS Treatment of Diabetic Polyneuropathy (HTEMS-RCT)

Diabetic Polyneuropathy

Germany
West German Center of Diabetes and Health
gbo Medizintechnik AG

Completed

High-tone External Muscle Stimulation for Pain Reduction (HTEMS)

Chronic Radicular Back Pain | Lumboischialgia | Cervico Brachialgia

Germany
German CLL Study Group
Mundipharma Pte Ltd.; Roche Pharma AG

Completed

FCR or BR in Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Germany
German Breast Group
GlaxoSmithKline; Roche Pharma AG; Teva Pharmaceuticals USA

Completed

Addition of Carboplatin to Neoadjuvant Therapy for Triple-negative and HER2-positive Early Breast Cancer (GeparSixto)

Inflammatory Breast Cancer | HER-2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III | Inflammatory Breast Cancer Stage IV

Germany
TME Pharma AG
German Federal Ministry of Education and Research

Completed

NOX-A12 First-in-human (FIH) Study

Autologous Stem Cell Transplantation

Germany
Charite University, Berlin, Germany
NeuroCure Clinical Research Center, Charite, Berlin; Brahms AG

Completed

Stroke Adverse Outcome is Associated With Nosocomial Infections: PCTus- Guided Antibacterial Therapy in Severe Ischemic Stroke Patients (STRAWINSKI) (STRAWINSKI)

Ischemic Stroke

Spain, Germany
University of Erlangen-Nürnberg Medical School
University of Erlangen-Nürnberg; Siemens AG; Bavarian Research Foundation, Munich... and other collaborators

Completed

Effects of Whole-body Electromyostimulation and Dietary Supplements on "Sarcopenic Obesity"

Sarcopenic Obesity
German Breast Group
Sanofi; Roche Pharma AG; Amgen; University Hospital Frankfurt

Completed

Docetaxel, Doxorubicin and Cyclophosphamide Versus Vinorelbine and Capecitabine in Patients Not Sufficiently / Sufficiently Responding as Preoperative Treatment of Locally Advanced or Operable Primary Breast Cancer (GeparTrio)

Breast Cancer
German Breast Group
Roche Pharma AG; Amgen; Teva Pharmaceuticals USA; Vifor Pharma

Completed

A Phase III Trial Comparing Two Dose-dense, Dose-intensified Approaches (ETC and PM(Cb)) for Neoadjuvant Treatment of Patients With High-risk Early Breast Cancer (GeparOcto)

Inflammatory Breast Cancer | HER2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III

Germany
Philipps University Marburg Medical Center
Deutsche Krebshilfe e.V., Bonn (Germany); AOP Orphan Pharmaceuticals AG

Completed

ENDURE - Efficacy and Safety of AOP2014 With CML Patients in Remission (ENDURE-CML-IX)

Chronic Myeloid Leukemia in Remission

France, Germany
A. Vogel AG
Daacro GmbH & Co. KG, Max-Planck-Str. 22, 54296 Trier/Germany

Not yet recruiting

Sleep Well Observation Study

Sleep Disturbance

Germany
SepNet - Critical Care Trials Group
Novo Nordisk A/S; German Federal Ministry of Education and Research; B. Braun... and other collaborators

Completed

Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)

Septic Shock | Severe Sepsis

Germany
Oncoscience AG
University of Kiel; Marienhospital Herne; Gemeinschaftspraxis für Hämatologie... and other collaborators

Completed

Nimotuzumab in Adults With Pancreatic Cancer

Pancreatic Cancer, Advanced or Metastatic

Germany

Clinical Trials Sponsored by DeveloGen AG, Germany

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