Clinical Trials Sponsored by Fondation avenir

Total 17753 results

Aveni Foundation

Withdrawn

CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 (CORONA)

COVID-19 | Acute Respiratory Distress Syndrome | Cytokine Storm
Aveni Foundation

Available

Expanded Access for DeltaRex-G for Osteosarcoma, Chondrosarcoma, Soft Tissue Sarcoma, Pancreas and Breast Cancer

Sarcoma | Soft Tissue Sarcoma | Pancreatic Cancer | Osteosarcoma | Chondrosarcoma | Chordoma | Carcinoma of Breast | MPNST (Malignant Peripheral Nerve Sheath Tumor)

United States
Centre Francois Baclesse
Fondation avenir; laboratoire Genzyme

Completed

Diagnostic Value of Molecular Cytological Analysis (CMA) and Shear Wave Elastography ShearWave (SWE) in Patients With a Thyroid Nodule With Indeterminate Cytology: Feasibility Study (SWEETMAC)

Thyroid Node | Indeterminate Cytology | Surgery Indication

France
Avanir Pharmaceuticals

Completed

Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Participants With Alzheimer's Disease

Alzheimer's Disease | Agitation

United States
Avanir Pharmaceuticals

Completed

Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Participants

Healthy Adult Male and Female Volunteers

United States
Avanir Pharmaceuticals

Terminated

Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA)

Pseudobulbar Affect (Involuntary Laughing and/or Crying)

United States
Avanir Pharmaceuticals

Completed

Efficacy and Safety of 20 mg Sumatriptan Powder Delivered Intranasally With the Bi-directional Device Compared With 100 mg Sumatriptan Tablets in Adults With Acute Migraine With or Without Aura (COMPASS)

Migraine | Headaches

United States
Avanir Pharmaceuticals

Completed

Safety and Efficacy of Dextromethorphan and Quinidine in the Treatment of the Pain of Diabetic Neuropathy

Pain | Diabetic Neuropathy

United States
Avanir Pharmaceuticals

Completed

Safety Study of AVP-923 in the Treatment of IEED (Involuntary Emotional Expression Disorder) Also Known as Pseudobulbar Affect (Episodes of Uncontrolled Crying and/or Laughter)

Stroke | Parkinson's Disease | Traumatic Brain Injury | Alzheimer's Disease

United States
Avanir Pharmaceuticals

Completed

Pharmacokinetics (PK) and Tolerability of AVP-786 in Healthy Volunteers

Healthy

Australia
Avanir Pharmaceuticals

Completed

Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis (PRIME)

Multiple Sclerosis | Central Neuropathic Pain

United States, Spain, Czechia, Poland, Argentina
Avanir Pharmaceuticals

Terminated

Safety, Tolerability and Efficacy of AVP-786 for the Treatment of Disinhibition

Disinhibition Syndrome

United States
Avanir Pharmaceuticals

Completed

Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Residual Schizophrenia

Schizophrenia

United States
Avanir Pharmaceuticals

Completed

Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA) (PRISM II)

Stroke | Dementia | Traumatic Brain Injury (TBI) | Pseudobulbar Affect (PBA)

United States
Avanir Pharmaceuticals

Completed

Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS

Amyotrophic Lateral Sclerosis

United States
Avanir Pharmaceuticals

Completed

Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment

Depressive Disorder, Treatment-Resistant

United States
Avanir Pharmaceuticals

Completed

Drug Interaction Study Between AVP-923 and Itraconazole and Between AVP-786 and Itraconazole in Healthy Adult Subejcts (DDI)

Healthy

United States
Avanir Pharmaceuticals

Completed

Safety and Efficacy of AVP-923 for Pseudobulbar Affect in Multiple Sclerosis Patients

Multiple Sclerosis

United States
Avanir Pharmaceuticals

Completed

A Phase 1 Study Comparing AVP-786 With AVP-923

Healthy Volunteer

United States
Avanir Pharmaceuticals

Completed

A Phase-1 Study to Assess the Pharmacokinetics, Safety and Tolerability of AVP-786 in Healthy Volunteers

Healthy

Australia
Avanir Pharmaceuticals

Completed

PRISM Registry: Pseudobulbar Affect Registry Series

Stroke | Parkinson's Disease | Traumatic Brain Injury | Amyotrophic Lateral Sclerosis (ALS) | Alzheimer's Disease | Multiple Sclerosis (MS)

United States
Hôpital Léon Bérard
Fondation de l'Avenir

Not yet recruiting

Effects of HIIT on HRV in Sub-acute Post-stroke Patients (E(AVC))

Stroke
Centre Francois Baclesse
Fondation de l'Avenir

Completed

Trial Comparing 2 Diagnostic Strategies for Preoperative Localization of Parathyroid Adenoma in Primary Hyperparathyroidism:TEMP / CT With Tc99m-sestaMIBI or PET / CT With F18-choline in First Intention (APACH2)

Hyperparathyroidism | Parathyroid Adenoma | F18-choline

France
University Hospital, Angers
Fondation de l'Avenir

Recruiting

MITAORTA - Role of Mitochondrial Dynamic in Aneurysm and Dissection of Ascending Thoracic Aorta (MITAORTA)

Aortic Aneurysm and Dissection

France
University Hospital, Toulouse
Fondation de l'Avenir

Recruiting

Neurorehabilitation After Traumatic Brain Injury: Functional Magnetic Resonance Imaging Study (RemCog-TC)

Traumatic Brain Injury

France
University Hospital, Toulouse
Fondation de l'Avenir

Completed

Evaluation Study of Fear of Cancer Recurrence: Detection, Measure and Risk Factors in Lymphoma Survivorship (PResEnCE)

Lymphoma

France
University Hospital, Toulouse
Fondation de l'Avenir

Completed

Follow-up After a Stay in Intensive Rehabilitation for Patients With Swallowing Disorders (E-CRIL)

Swallowing Disorders

France
Institut Mutualiste Montsouris
Fondation de l'Avenir

Unknown

Impact of the Addition of a Specific and Personalized Body Approach by Osteopathic Treatment in the Care of Adolescents With Anorexia Nervosa. (ACAMTO)

Anorexia Nervosa | Osteopathic Medicine

France
Rennes University Hospital
Fondation de l'Avenir

Recruiting

earlY Upper Limb Rehabilitation WIth EEG-Neurofeedback After Stroke (YUWIN-Stroke)

Stroke | Brain Infarction | Stroke, Ischemic | Stroke Hemorrhagic | Stroke Rehabilitation

France
Hospital Center Guillaume Régnier
Fondation de l'Avenir

Completed

Neurostimulation and OCD, a MRI Study (ASLTOC)

Obsessive Compulsive Disorder

France
Avanir Pharmaceuticals
Michael J. Fox Foundation for Parkinson's Research

Completed

Safety and Efficacy of AVP-923 in the Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease Patients (LID in PD)

Parkinson's Disease | Dyskinesia

Canada, United States
Royal Marsden NHS Foundation Trust
Aventis Pharmaceuticals

Completed

A Phase II Trial Evaluating Irinotecan Plus 5FU/LV in Patients With Relapsed/Refractory Upper GI Tumours

Upper Gastrointestinal Tumours
Avanir Pharmaceuticals
Syneos Health

Completed

Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS (STAR)

Pseudobulbar Affect (PBA)

United States, Argentina, Brazil
Assistance Publique - Hôpitaux de Paris
Fondation de l'Avenir

Recruiting

Kidney Function and Anorexia Nervosa (ANKID)

Anorexia Nervosa | Kidney Injury

France
Groupe Hospitalier Mutualiste de Grenoble
Fondation de l'Avenir

Completed

Evolution of Cardiovascular Function and Quality of Life in Patients Included in the SCArabée Therapeutic Education Program (SCArabée)

Acute Coronary Syndrome

France
University Hospital, Clermont-Ferrand
Medtronic; Fondation de l'Avenir

Completed

Study of Conscious Behavior Under Low-frequency Deep Brain Stimulation in Chronic and Severe Post-coma Disorders of Consciousness (Post-coma DBS)

Chronic and Severe Post-coma Disorders of Consciousness (Permanent Vegetative State, Minimally Conscious State)

France
Assistance Publique - Hôpitaux de Paris
Fondation de l'Avenir

Recruiting

Efficacy of the Application of Xylocaine Impregnated Compress in Reducing Per-procedural Pain During Ultrasound-guided Infiltration of Trigger Finger (SAUTYLO)

Trigger Finger

France
Assistance Publique - Hôpitaux de Paris
Fondation de l'Avenir

Completed

Single Port Colic Laparoscopic Surgery (TRUE)

Crohn's Disease | Diverticulitis | Colonic Neoplasms

France
University Hospital, Clermont-Ferrand
Fondation de l'Avenir, France

Unknown

Benefits of Therapy With Virtual Reality Exposure in the Treatment of Cocaine Use Disorders (CORVI)

Addiction | Cocaine-Related Disorders

France
Centre Hospitalier Universitaire de Nice
Fondation de l'Avenir

Unknown

Effects of the Soluble Mediators of Mastocytes on the Intestinal Epithelial Barrier and of the Enteric Nervous System During the Syndrome of the Irritable Bowel

Irritable Bowel Syndrome

France
Groupe Hospitalier Mutualiste de Grenoble
Fondation de l'Avenir

Completed

Health Course of Patients Undergoing Per os Anti-cancer Therapy. (MinOS)

Cancer

France
Cardiovascular Research Foundation, New York
Cardialysis BV; Avania

Active, not recruiting

Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)

Aortic Valve Stenosis

United States, Canada, Netherlands
Aveiro University
Foundation for Science and Technology, Portugal

Completed

Pain Neuroscience Education and Exercise in High School Students With Chronic Idiopathic Neck Pain

Chronic Neck Pain

Portugal
OrbusNeich
Avania

Not yet recruiting

Sapphire 3 CTO Study

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Artery Disease | Coronary Disease | Arteriosclerosis | Chronic Total Occlusion | Chronic Total Occlusion of Coronary Artery
Cochlear
Avania

Not yet recruiting

Clinical Performance of the Osia 3 Sound Processor Compared With the Osia 2 Sound Processor in Adult Osia Implant Users (RECONNECT)

Hearing Loss, Conductive | Hearing Loss, Mixed Conductive-Sensorineural

Australia
ONY
Avania

Not yet recruiting

InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS (Aero-05)

Intubation Complication | Death; Neonatal | Respiratory Distress Syndrome (Neonatal)

United States
Aveiro University

Completed

Acute Effects of Action Observation on Neck Pain

Neck Pain

Portugal
Aveiro University

Completed

Immediate Exercise-Induced Hypoalgesia in Patients With Chronic Low Back Pain

Low Back Pain

Portugal
Aveiro University

Completed

Pain Neuroscience Education and Gradual Exposure to Exercise in Factory Workers With Chronic Low Back Pain

Low Back Pain

Portugal
Aveiro University

Completed

Effect of Nervous System Mobilization on Athletes' Performance

Healthy

Portugal

Clinical Trials Sponsored by Fondation avenir

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