Clinical Trials Sponsored by GeneDx

Total 1103 results

Genelux GmbH

Completed

A Study of GL-ONC1, an Oncolytic Vaccinia Virus, in Patients With Advanced Peritoneal Carcinomatosis

Peritoneal Carcinomatosis

Germany
Geneos Therapeutics

Active, not recruiting

GNOS-PV02 Personalized Neoantigen Vaccine, INO-9012 and Pembrolizumab in Subjects With Advanced HCC

HCC

United States, New Zealand
Genelux Corporation

Temporarily not available

Expanded Access to Provide GL-ONC1 for the Treatment of Advanced Cancers With No Standard of Care

Advanced Stage Cancer (Solid Tumor Disease for 4 Patients) | Acute Myeloid Leukemia (6 Patients)

United States
Genelex Corporation

Completed

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome P450 CYP2C9 Enzyme Deficiency | Cytochrome P450 CYP2C19 Enzyme Deficiency | Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant | CYP2D6 Polymorphism | Ultrarapid... and other conditions

United States
Genelux Corporation

Completed

Safety Study of GL-ONC1, an Oncolytic Virus, in Patients With Advanced Solid Tumors

Advanced Cancers (Solid Tumors)

United Kingdom
Genelux Corporation

Completed

GL-ONC1 Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Carcinomatosis

United States
Genelux Corporation

Completed

Safety Study of Attenuated Vaccinia Virus (GL-ONC1)With Combination Therapy in Head & Neck Cancer

Cancer of Head and Neck

United States
University of Geneva, Switzerland
University Hospital, Geneva

Recruiting

The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring (OPTIMAL TDM)

Efficacy | Toxicity | Beta-lactam Antibiotics | Therapeutic Drug Monitoring | Ceftazidime | Amoxicillin | Meropenem | Imipenem | Piperacillin | Flucloxacillin | Cefepime

Switzerland
University Hospital, Geneva
University of Geneva, Switzerland

Active, not recruiting

Effects of a Novel Neurofeedback Protocol on ADHD Subcomponents (NFB@HOME)

Attention Deficit Disorder With Hyperactivity

Switzerland
University of Geneva, Switzerland
University Hospital, Geneva

Completed

Effect of Acute Physical Exercise on Memory (SPEMO)

Acute Physical Exercise
University Hospital, Geneva
University of Geneva, Switzerland

Recruiting

Mental Imagery and Targeted Memory Reactivation in Insomnia

Insomnia Disorder

Switzerland
University Hospital, Geneva
University of Geneva, Switzerland

Recruiting

Anhydroglucitol in Children With Type 1 Diabetes

Diabetes Mellitus, Type 1

Switzerland
University of Geneva, Switzerland
University Hospital, Geneva

Not yet recruiting

Improving Awareness for Spatial Neglect With tDCS (ANOSO)

Stroke | Anosognosia | Neglect, Hemispatial
University Hospital, Geneva
University of Geneva, Switzerland

Completed

Understanding COVID-19

SARS-CoV-2 Viral Kinetics and Host Immune Responses

Switzerland
University Hospital, Geneva
University of Geneva, Switzerland

Recruiting

Investigating Surprise Signals in the Anterior Insula

Healthy | Drug Resistant Epilepsy

Switzerland
University Hospital, Geneva
University of Geneva, Switzerland

Completed

Benefits of Tablet-based Serious Games to Promote Speech Production in Young Children With Hearing Disabilities (FunSpeech)

Hearing Loss | Deafness

Switzerland
University Hospital, Geneva
University of Geneva, Switzerland

Completed

Evaluation of an Innovative Speech-enabled Translator in Emergency Settings

Diagnoses Disease

Switzerland
School of Health Sciences Geneva
University Hospital, Geneva

Recruiting

Transcranial Direct Current Stimulation for Gait Recovery Following Stroke (TransGait)

Stroke | Gait, Hemiplegic

Switzerland
University Hospital, Geneva
Geneva University, School of medicine

Completed

Assessing Parathyroid Glands Vascularisation by ICG Fluoroscopy

Parathyroid Function Low Adverse Event

Switzerland
University Hospital, Geneva

Recruiting

Effect of Dopamine on Specific Processing of Shame and Embarrassment in Parkinson's Disease (BioDopa)

Parkinson Disease

Switzerland
University Hospital, Geneva

Not yet recruiting

Middle Meningeal Artery Embolization for Chronic Subdural Hematomas (STORMM) (STORMM)

Chronic Subdural Hematomas | Cerebral Compression Due to Injury
University Hospital, Geneva

Recruiting

Respiratory Effects of Flow-Controlled Ventilation and Jet Ventilation in Patients Undergoing Laryngotracheal Surgery (Flowjet)

Anesthesia, General | Ventilation | Lung Function

Switzerland
University Hospital, Geneva

Recruiting

Mental Imagery and Targeted Memory Reactivation in PTSD

PTSD | Nightmares, REM-Sleep Type

Switzerland
University Hospital, Geneva

Recruiting

Bleeding of Unknown Cause: a Swiss Case-control Study (SWISS-BUC)

Bleeding Disorder

Switzerland
University Hospital, Geneva

Recruiting

Risk of CYP2C19 Phenoconversion in Healthy Volunteers With Rapid, Normal, and Intermediate Predicted Metabolizers' Status (Switch19)

Healthy

Switzerland
University Hospital, Geneva

Recruiting

Muscle Ultrasound Study in Shock Patients (MUSiShock)

Septic Shock

Switzerland
University Hospital, Geneva

Recruiting

Patient-derived Organoids of Lung Cancer to Test Drug Response

Lung Cancer | Organoid

Switzerland
University Hospital, Geneva

Recruiting

Congenital Lung Anomalies (CLA) Swiss Database (CLADatabase)

Pleuropulmonary Blastoma | Bronchogenic Cancer | Congenital Lung Malformation | Congenital Lung Cyst | Sequestrum | Acinar Dysplasia

Switzerland
University Hospital, Geneva

Recruiting

Does Preventive Uterine Artery Occlusion During Laparoscopic Myomectomy Impact on Ovarian Reserve Markers? (ORAM)

Uterine Myoma

Switzerland
University Hospital, Geneva

Completed

Predictive Value of Nu.Q™ Biomarkers to Help Guiding the Management of Osteoarticular Infections

Diabetic Foot | Septic Arthritis | Chronic Osteomyelitis

Switzerland
University Hospital, Geneva

Completed

Non-Invasive Measurement of SjvO2 Using Near Infrared Spectroscopy in Patients Undergoing Liver Transplantation Surgery

Transplant; Failure, Liver | Impaired Oxygen Delivery

Switzerland
University Hospital, Geneva

Completed

Saline-induced Distal to Aortic Coronary Pressure Ratio vs. Resting and Hyperemic Indices of Coronary Artery Stenosis Severity (SALINE)

Coronary Stenosis

Switzerland
University Hospital, Geneva

Withdrawn

Pupillometry Guided Remifentanil Administration In Pediatric Anesthesia

Pain | Child | Anesthesia

Switzerland
ReNetX Bio, Inc.

Completed

AXER-204 in Participants With Chronic Spinal Cord Injury (RESET)

Chronic Spinal Cord Injury

United States
University Hospital, Geneva

Terminated

Prospective, Open Label Study to Assess 24hs IOP Recorded With Triggerfish® in Patients With OAG Before and After DSCI

Open Angle Glaucoma

Switzerland
The Geneva Foundation

Terminated

The Prevalence of Nonalcoholic Fatty Liver Disease (NAFLD) Pediatric Patients

Obesity, Childhood | Hemosiderosis | Liver Steatosis | Steatohepatitis, Nonalcoholic | Overweight Adolescents

United States
University Hospital, Geneva

Terminated

Physical Deconditioning in COVID-19 Positive Patients and Non-Specific Low Back Pain (Phydel)

Low Back Pain, Mechanical

Switzerland
University Hospital, Geneva

Completed

One-time Informed Consent for Research in Prison

Informed Consent

Switzerland
University Hospital, Geneva

Terminated

Does Oral Desogestrel Prior to Insertion of the Etonogestrel Subdermal Implant Improve Continuation Rate at One Year?

Contraception | Progestogen Adverse Reaction
University Hospital, Geneva

Completed

Perceived Impact of the COVID-19 Pandemic on Medical Management and Symptoms in a High Risk Group

COVID-19 Pandemic | Long-term Non-invasive Ventilation | Vulnerable Subjects

Switzerland
University Hospital, Geneva

Completed

Exploring the Impact of Biofeedback on the Inhibitory Control of Healthy Older Adults (I-BF)

Inhibition

Switzerland
University Hospital, Geneva

Completed

Glucocorticosteroid Treatment in Acute Unilateral Vestibulopathy (Vestibular Neuronitis)

Acute Peripheral Vestibulopathy
University Hospital, Geneva

Active, not recruiting

Bioavailability and Pharmacokinetics of Calcium Dobesilate (Doxium®) in the Nasal Mucosal Tissue, Saliva and Blood of Treated Patients (CaDoBio)

Biological Availability

Switzerland
University Hospital, Geneva

Completed

Immune Durability After VSV-EBOV Vaccination

Immune Response | Vaccination | Durability
University Hospital, Geneva

Completed

Fast-track in Minimally Invasive Gynaecology

Gynecologic Disease

Switzerland
University Hospital, Geneva

Completed

Human Papillomavirus (HPV) Self-sampling as a Test of Cure After Treatment of Cervical Intra-epithelial Neoplasia

Cervical Intra-epithelial Neoplasia Grade 1 or Worse

Switzerland
University Hospital, Geneva

Completed

An Ecological Analysis of Nontuberculous Mycobacteria in the Geneva Area (2015-2020)

Ecology of Nontubercuous Mycobacteria | Geneva Area

Switzerland
University Hospital, Geneva

Completed

Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration

Cholecystitis | Cholangitis | Choledocholithiasis | Gallstone Pancreatitis | Gallstone Migration

Switzerland
University Hospital, Geneva

Completed

Less Infections for the Diabetic Foot

Diabetic Foot

Switzerland
University Hospital, Geneva

Completed

Chewing Efficiency Measured by a Two Colour Chewing Gum Test in Amyotrophic Lateral Sclerosis (ALS) Patients?

Amyotrophic Lateral Sclerosis 11

Switzerland

Clinical Trials Sponsored by GeneDx

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