Clinical Trials Sponsored by Health and Human Services Commission (HHSC)

Total 292 results

University of Texas Rio Grande Valley
Health and Human Services Commission (HHSC); Pharr-San Juan-Alamo Independent... and other collaborators

Active, not recruiting

South Texas Early Prevention Studies SNAP-Ed (STEPS SNAP-Ed) (STEPSSNAP-Ed)

Health-Related Behavior

United States
Seqirus
Department of Health and Human Services

Recruiting

Study to Evaluate Immunogenicity, Safety and Tolerability of Adjuvanted and Non-Adjuvanted H2N3 Influenza Vaccines in Adults

Infections | Virus Diseases | Respiratory Tract Infections | Influenza, Human | Infection Viral

Philippines, United States
Novavax
Department of Health and Human Services

Completed

A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2

Covid19 | SARS-CoV Infection

United States, Mexico, Puerto Rico
Novavax
Department of Health and Human Services

Completed

A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 2

Influenza (Pandemic)

United States
Novavax
Department of Health and Human Services

Completed

A Study to Evaluate the Immune Response and Safety of a Seasonal Virus-Like Particle Influenza Vaccine in Healthy Young Adults

Influenza

Australia
Novavax
Department of Health and Human Services

Completed

A(H7N9) VLP Antigen Dose-Ranging Study With Matrix-M1™ Adjuvant

Influenza (Pandemic)

United States
Novavax
Department of Health and Human Services

Completed

Quadrivalent Influenza VLP Vaccine Dose Ranging Study in Young Adults

Influenza

United States
Novavax
Department of Health and Human Services

Completed

A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 1

Influenza (Pandemic)

United States
Winter Rose Services, LLC
Department of Health and Human Services

Unknown

Evaluation of Curriculum for Teen Pregnancy Prevention: Decisions, Responsibility, Empowerment, Accountability, Motivations & Success (DREAMS)

Teen Pregnancy

United States
NYU Langone Health
Department of Health and Human Services

Recruiting

Promoting Equitable Access to Language Services in Health and Human Services

Appropriate Use of Language Across Services

United States
Emergent BioSolutions
Department of Health and Human Services

Completed

Safety Study of 7 Botulinum Antitoxin Serotypes Derived From Horses

Healthy

United States
Emergent BioSolutions
Department of Health and Human Services

Completed

Ciprofloxacin BioThrax Co-Administration Study

Anthrax

United States
Emergent BioSolutions
Department of Health and Human Services

Completed

Safety and Pharmacokinetic Study of Anthrax Immune Globulin Derived From Human Serum

Symptoms of Inhalational Anthrax

United States
Northwestern University
Department of Health and Human Services

Completed

Respiratory Infection Monitoring

Chronic Obstructive Pulmonary Disease (COPD)

United States
Temple University
Department of Health and Human Services

Completed

Game on Philly: Engaging Underserved Middle School Youth in Out-of- School Time Sports and Nutrition Education

Exercise | Diet

United States
Northwestern University
Department of Health and Human Services

Completed

The Northwestern University Two-Generation Study of Parent and Child Human Capital Advancement (NU2Gen)

Children | Parents

United States
Neumedicines Inc.
Department of Health and Human Services

Completed

Safety and Tolerability of HemaMax™ (rHuIL-12) as Radiation Countermeasure

Hematopoietic Syndrome Due to Acute Radiation Syndrome

United States
BioCryst Pharmaceuticals
Department of Health and Human Services

Completed

Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected Influenza

Fatigue | Myalgia | Cough | Headache | Nasal Congestion | Seasonal Influenza | Sore Throat

United States, Mexico, Canada, Australia, New Zealand, Puerto Rico
Cellerant Therapeutics
Department of Health and Human Services

Completed

Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Cord Blood Transplant for Hematologic Malignancy

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Plasma Cell Neoplasm

United States
MedImmune LLC
Department of Health and Human Services

Completed

A Study to Evaluate the Safety of HIN1 Monovalent Vaccine (MEDI3414) in Children 2 to 17 Years of Age (MI-CP217)

Influenza

United States
Gallaudet University
Department of Health and Human Services

Recruiting

Auditory-Cognitive Training to Optimize Outcomes for Older CI Users (ARCog)

Hearing Loss | Deafness

United States
Emergent BioSolutions
Department of Health and Human Services

Completed

Botulism Antitoxin Effects on Paralysis Induced by Botulinum Neurotoxins in the EDB Muscle

Healthy Volunteers

United States
SRI International
Department of Health and Human Services

Terminated

Evaluation of the SRI B. Anthracis Lethal Factor Diagnostic System

Anthrax

United States
Northwestern University
Department of Health and Human Services

Completed

Expanding the Cycle of Opportunity: Simultaneously Educating Parents and Children in Head Start (CAPFAST)

Children | Parents

United States
Neumedicines Inc.
Department of Health and Human Services

Completed

Safety Study of HemaMax™ (rHuIL-12) to Treat Acute Radiation Syndrome

Hematopoietic Syndrome Due to Acute Radiation Syndrome

United States
Regeneron Pharmaceuticals
Department of Health and Human Services

Completed

Study of Safety, Tolerability, and Pharmacokinetics of REGN3470-3471-3479 in Healthy Adult Volunteers

Healthy Volunteers

United States
Pfenex, Inc
Department of Health and Human Services

Completed

A Study of Anthrax Vaccines Px563L and RPA563 in Healthy Adult Subjects

Anthrax

United States
Cellerant Therapeutics
Department of Health and Human Services

Completed

Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Chemotherapy for Leukemia

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplasia

United States
BioCryst Pharmaceuticals
Department of Health and Human Services

Terminated

A Study to Evaluate the Efficacy and Safety of Intravenous Peramivir in Subjects With Uncomplicated Influenza.

Influenza

United States
Achaogen, Inc.
Department of Health and Human Services

Completed

PK Study of ACHN-490 Injection in Renally Impaired Subjects

Renal Insufficiency
Achaogen, Inc.
Department of Health and Human Services

Completed

A Study to Evaluate the Effect of IV ACHN-490 Injection on the QT/QTc Interval in Healthy Volunteers

Cardiac Effects in Normal Healthy Volunteers

United States
MedImmune LLC
Department of Health and Human Services

Completed

A Study to Evaluate the Safety of H1N1 Monovalent Vaccine (MEDI3414) in Healthy Adults (MI-CP215)

Healthy

United States
Yale University
Department of Health and Human Services

Not yet recruiting

Project Women's Insomnia Sleep Health Equity Study (WISHES) (Project WISHES)

Insomnia | Cardiometabolic Health | Sleep Health

United States
Emergent BioSolutions
Department of Health and Human Services

Completed

Immunogenicity and Safety Study of a Three-Dose BioThrax® Regimen for Post-Exposure Prophylaxis in Healthy Adults

Anthrax

United States
Mayo Clinic
Department of Health and Human Services

Completed

A Study of the GRIP Influenza and SARS-CoV-2 POC Assays

COVID-19 | Influenza

United States
Basilea Pharmaceutica
Department of Health and Human Services

Completed

Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia

Staphylococcus Aureus Bacteremia

Israel, United States, Georgia, Russian Federation, Ukraine, Colombia, Argentina, Bulgaria, Germany, Greece, Italy, Mexico, Panama, Serbia, South Africa, Spain, Turkey
Summit Therapeutics
Department of Health and Human Services

Terminated

Safety, Tolerability and the Pharmacokinetics of Ridinilazole in Adolescent Subjects (Ri-CoDIFy 3)

Clostridioides Difficile Infection

United States
MRI Global
Department of Health and Human Services

Completed

Febrile Whole Blood Specimen Collection and Testing

Anthrax | Febrile Infection

United States
Achaogen, Inc.
Department of Health and Human Services

Completed

A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE) (CARE)

Bloodstream Infections (BSI) Due to CRE | Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE | Ventilator-Associated Bacterial Pneumonia (VABP) Due to CRE | Complicated Urinary Tract Infection (cUTI) Due to CRE | Acute Pyelonephritis (AP) Due to CRE
Cellerant Therapeutics
Department of Health and Human Services

Completed

Safety and Efficacy of Human Myeloid Progenitor Cells (CLT-008) During Chemotherapy for Acute Myeloid Leukemia

Acute Myeloid Leukemia | Neutropenia | Infection

United States
Arteriocyte, Inc.
Department of Health and Human Services

Unknown

Applying Platelet Rich Plasma (PRP) Gel to Acute Deep Partial Thickness Thermal Injuries

Acute Deep Partial Thickness Thermal Burns

United States
BioCryst Pharmaceuticals
Department of Health and Human Services

Terminated

A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standard of Care Alone in Adults and Adolescents Who Are Hospitalized Due to Influenza

Cough | Fever | Headache | Nasal Congestion | Seasonal Influenza | Sore Throat

United States, Poland, Ukraine, Germany, Belgium, Argentina, Israel, Bulgaria, Serbia, South Africa, Brazil, Canada, Chile, Peru, Russian Federation, Hungary, Czech Republic, India, United Kingdom, Latvia, Bosnia and Herzegovina, ... and more
University of California, San Francisco
Department of Health and Human Services; Youth+Tech+Health; Fresno Economic Opportunities...

Completed

Personal Responsibility Education Program Innovative Strategies: Digital Initiative for Youth (PREIS)

Sexually Transmitted Diseases | Contraception | Reproductive Health

United States
Denver Health and Hospital Authority
Department of Health and Human Services

Active, not recruiting

Increasing Linkage to Family Planning Care for Individuals With Substance Use Disorder

Substance-Related Disorders | Opiate Substitution Treatment | Family Planning Services | Sexual Health

United States
Northwestern Health Sciences University
Department of Health and Human Services

Completed

Chiropractic and Self-care for Back-Related Leg Pain

Sub-acute and Chronic Back-related Leg Pain

United States
Public Health Management Corporation
Department of Health and Human Services

Completed

Evaluation of the Talking Matters Teen Pregnancy Prevention Program

Pregnancy in Adolescence

United States
Peptilogics
Wellcome Trust; Department of Health and Human Services

Recruiting

Study in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA)

Joint Infection

United States
WestEd
Department of Health and Human Services; Urban Strategies

Recruiting

Opportunities Beyond the Narrative: An Intervention for Justice-Involved Youth

Study Will Examine the Impact of Project With

United States
University of Washington
Department of Health and Human Services

Recruiting

Telehealth Pain Self-Management for Employed Adults (E-TIPS)

Multiple Sclerosis | Chronic Pain | Brain Injuries, Traumatic | Amputation | Spinal Cord Injuries

United States
Thomas Jefferson University
Department of Health and Human Services

Completed

Zoledronic Acid in Acute Spinal Cord Injury

Spinal Cord Injury

United States

Clinical Trials Sponsored by Health and Human Services Commission (HHSC)

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