Clinical Trials Sponsored by Hoxworth Blood Center

Total 1206 results

Italo Biaggioni
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Sympathetic Mechanisms in the Cardiovascular and Metabolic Alterations of Obesity

Obesity-Associated Insulin Resistance

United States
University of Texas Southwestern Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Extreme Lipids Repository

Lipoprotein Disorder

United States
Center for International Blood and Marrow Transplant...
Sanofi; Genzyme, a Sanofi Company

Completed

A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor

Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Hodgkin's Disease | Related Donors Donating Peripheral Blood Stem Cells (PBSC) to a Family Member

United States
Boston Medical Center
National Heart, Lung, and Blood Institute (NHLBI); Boston Children's Hospital

Completed

Pilot Simulation RCT of Telemedical Support for Paramedics

Respiratory Failure | Status Epilepticus | Status Asthmaticus | Cardiopulmonary Arrest

United States
University of Texas Southwestern Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mechanisms and Treatment of Intradialytic Hypertension (MATCH)

Intradialytic Hypertension

United States
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Phase II Investigation of Antimycobacterial Therapy on Progressive, Pulmonary Sarcoidosis

Sarcoidosis; Antimycobacterial Therapy

United States
University of Texas Southwestern Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Priapism in Boys and Men With Sickle Cell Disease - Demographics, Characteristics and Prevalence

Anemia, Sickle Cell | Priapism

United States
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A ED-based Intervention to Improve Antihypertensive Adherence

Hypertension | Blood Pressure | Hypertensive Emergency

United States
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study on the Role of Treatment With Vitamin E on Asthmatic Responses in Allergic Asthmatics

Allergic Asthma

United States
Center for International Blood and Marrow Transplant...
MedImmune LLC; National Marrow Donor Program; Pediatric Blood and Marrow Transplant... and other collaborators

Terminated

Moxetumomab Pasudotox (CAT-8015, HA22) in Children With B-lineage Acute Lymphoblastic Leukemia and Minimal Residual Disease Prior to Allogeneic Hematopoietic Stem Cell Transplantation

Acute Lymphoblastic Leukemia (ALL)

United States
University of Texas Southwestern Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

The Genetic, Protein, and Lipid Basis of Variation in Cholesterol Efflux

Lipid Metabolism Disorders

United States
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Treatment of Orthostatic Hypotension

Autonomic Nervous System Diseases | Orthostatic Hypotension | Orthostatic Intolerance | Dopamine Beta-Hydroxylase Deficiency

United States
University of Texas Southwestern Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension

Hypertension

United States
Otsuka Pharmaceutical Development & Commercialization...
Center for International Blood and Marrow Transplant Research

Completed

PK-directed Dose Adjustment of IV Busulfan Conditioning Regimen for Autologous Stem Cell Transplant in Lymphoma Patients

Lymphoma

United States, Canada
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health Clinical Center (CC); National Cancer Institute...

Recruiting

Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

Stem Cell Transplantation | Sickle Cell Disease | Thalassemia | Graft vs Host Disease

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Web-based Patient Reported Outcome Measurement Information System (PROMIS ) to Explore Burden and Stress in Cancer Caregivers (BaSiC2)

Stress

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Treatment of Sickle Cell Anemia With Stem Cell Transplant

Sickle Cell Anemia | Sickle Cell-hemoglobin C Disease | Sickle Cell-β0-thalassemia

United States
University of Michigan Rogel Cancer Center
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

Prehabilitation Program to Improve Cardiac Reserve in High-Risk Patients Undergoing Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplant

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury

Thrombocytopenia | Surgery | Acute Kidney Injury | Hemolysis

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

A Pilot Factorial Trial of an Integrated Lifestyle Intervention

Overweight and Obesity | Physical Inactivity

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes (T1-DISCO)

Diabetes Mellitus, Type 1

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes (MANATEE-T1D)

Cardiovascular Diseases | Type 1 Diabetes | Diabetic Kidney Disease | Endothelial Dysfunction | Insulin Sensitivity

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Linking Temporal Patterns of Modifiable Behaviors to Weight Loss Outcomes

Obesity | Weight Change, Body

United States
OHSU Knight Cancer Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Research Study in Healthy Volunteers of Patients With Fanconi Anemia, Myeloproliferative Disorders, or Myeloma

Chronic Myeloproliferative Disorders | Fanconi Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women (SHAPE2)

Menopause | Aging

United States
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Women's Health Trial: Feasibility Study in Minority Populations

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Postmenopause
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Peripheral Stem Cell Transplant in Treating Patients With High-Risk Leukemia

Leukemia | Chronic Myeloproliferative Disorders | Myelodysplastic/Myeloproliferative Diseases

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI); University of Texas Southwestern...

Terminated

Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell Disease

Hematologic Diseases | Anemia, Sickle Cell

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Skeletal Effects of Chronic Night Shift (ACORN)

Osteoporosis | Circadian Rhythm Sleep Disorder, Shift Work Type

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth (PUBERTY)

Gender Dysphoria | Insulin Sensitivity | Transgenderism

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Pulmonary Health in Children With Down Syndrome

Down Syndrome | Dysphagia, Oropharyngeal

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A 12-week Field Trial of the Move Physical Activity Support Program

Overweight and Obesity | Physical Inactivity

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Targeting Physical Activity to Improve Cardiovascular Health in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Motor Activity | Health Behavior

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Improving Quality of Life in Heart Failure

Heart Failure | Quality of Life

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Effects of Resveratrol and Acute Exercise on Endothelial Function in Postmenopausal Women

Endothelial Dysfunction

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Coronary Artery Calcification in Type 1 Diabetes

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus | Diabetes Mellitus, Insulin-dependent
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluating the Effect of Neighborhood Environments on Cardiovascular Risk Factors

Cardiovascular Diseases

United States
Roswell Park Cancer Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myelodysplastic-Myeloproliferative Diseases

United States
Australian and New Zealand Intensive Care Research...
University College Dublin; King Abdulaziz Medical City; Australian Red Cross; New... and other collaborators

Completed

Standard Issue Transfusion Versus Fresher Red Blood Cell Use in Intensive Care- A Randomised Controlled Trial (TRANSFUSE)

Transfusion | Age of Blood

Ireland, Australia, New Zealand, Finland, Saudi Arabia
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Using AI Text Messaging to Improve AHA's Life's Essential 8 Health Behaviors

Cardiovascular Diseases | Lifestyle Factors

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Reducing Asthma Attacks in Disadvantaged School Children With Asthma

Asthma in Children

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

BiPAP in Pediatric Moderate to Severe Asthma Randomized Control Trial

Asthma in Children

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Optimizing Pulsatility During Cardiopulmonary Bypass

Acute Kidney Injury | Endothelial Dysfunction

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Skeletal Response to Simulated Night Shift (SPOTLIGHT)

Osteoporosis | Circadian Rhythm Sleep Disorder, Shift Work Type

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Bright Light Exposure in Critical Ill Patients

Myocardial Ischemia | Critical Illness | Endothelial Dysfunction

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI)

Recruiting

The National Myelodysplastic Syndromes (MDS) Study (MDS)

Myelodysplastic Syndromes (MDS)

United States, Israel
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Melanoma

Recurrent Melanoma | Stage IV Melanoma

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications

Cardiovascular Diseases | Coronary Artery Disease | Hypertension | Diabetes Mellitus | Atrial Fibrillation | Hyperlipidemias | Medication Adherence | Adherence, Medication

United States
Dana-Farber Cancer Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study Of Weight-Based Versus Standard Dose Enoxaparin Thromboprophylaxis In High-Risk Hospitalized Cancer Patients

Venous Thormboembolism

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Heart Failure Management Program Versus Usual Care

Congestive Heart Failure | Cardiac Failure

United States

Clinical Trials Sponsored by Hoxworth Blood Center

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