Clinical Trials Sponsored by Hythem Nawaytou

Total 313 results

Hythem Nawaytou
University of Minnesota

Recruiting

PV Loop and Pulmonary Hypertension

Pulmonary Vascular Resistance Abnormality

United States
Phythea

Completed

Renal and Digestive Tolerance of a Food Supplement, Phytalgic, in Elderly Volunteers - A Multicentric Open Trial

Renal Tolerance | Digestive Tolerance

France
Rhythm Pharmaceuticals, Inc.

Recruiting

A Study of RM-718 in Healthy Subjects and in Patients With HO

Hypothalamic Obesity

United States
Rhythm Pharmaceuticals, Inc.

Not yet recruiting

A Study to Assess Efficacy and Safety of LB54640 in Patients With Hypothalamic Obesity

Hypothalamic Obesity
Rhythm Pharmaceuticals, Inc.

Active, not recruiting

DAYBREAK: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway

Genetic Obesity

United States, Spain, Netherlands, Germany, United Kingdom, Canada, Israel, Greece
Rhythm Pharmaceuticals, Inc.

Completed

Open-Label Study of Setmelanotide in Hypothalamic Obesity

Hypothalamic Obesity

United States
Rhythm Pharmaceuticals, Inc.

Completed

Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients

Overweight and Obesity

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

Leptin Receptor Deficiency Obesity

Netherlands, Germany, United Kingdom, Canada, France, Réunion
Rhythm Pharmaceuticals, Inc.

Approved for marketing

An Expanded Access Protocol for Setmelanotide for Treatment of Bardet-Biedl Syndrome (BBS)

Obesity | Bardet-Biedl Syndrome (BBS)
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in a Single Patient With Partial Lipodystrophy

Obesity | Hypertriglyceridemia

United States
Rhythm Pharmaceuticals, Inc.

Completed

An Observational,Prospective Natural History Study of Early-Onset Extreme Obesity Due to Bi-Allelic Loss-of-Function Mutations in the POMC, PCSK1 or LEPR Genes (NHS)

POMC Deficiency Obesity | PCSK1 Deficiency Obesity | LEPR Deficiency Obesity

Turkey
Rhythm Pharmaceuticals, Inc.

Completed

A Phase 1 Study to Evaluate the Pharmacokinetics of Setmelanotide in Subjects With Varying Degrees of Renal Impairment

Renal Insufficiency

United States
Rhythm Pharmaceuticals, Inc.

Completed

The TEMPO (Tracing the Effect of the MC4 Pathway in Obesity) Registry

Genetic Forms of Extreme Obesity

United States, Canada
Rhythm Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RM-493 Administered to Healthy, Obese, Non-diabetic Volunteers

Overweight | Obese
Rhythm Pharmaceuticals, Inc.

Active, not recruiting

Long Term Extension Trial of Setmelanotide

Obesity Associated With Defects in Leptin-melanocortin Pathway

United States, Netherlands, Canada, Germany, United Kingdom, France, Greece, Spain
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

Bardet Biedl Syndrome (BBS) | Alström Syndrome (AS)

United States, United Kingdom, France, Canada, Puerto Rico, Spain
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in Pediatric Patients With Rare Genetic Diseases of Obesity

Bardet-Biedl Syndrome | POMC Deficiency Obesity | PCSK1 Deficiency Obesity | LEPR Deficiency Obesity

United States, Australia, Spain, United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

Pro-opiomelanocortin (POMC) Deficiency Obesity

Belgium, United States, Canada, France, Germany, Spain, United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

Obesity | Genetic Obesity | Obesity Due to Melanocortin 4 Receptor Deficiency

United States, United Kingdom, Germany, Netherlands, France, Canada, Greece, Israel, Spain
Rhythm Pharmaceuticals, Inc.

Recruiting

EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway

Obesity | Genetic Obesity

United States, Spain, Germany, Netherlands, United Kingdom, Greece, Puerto Rico, Canada, France, Israel
Rhythm Pharmaceuticals, Inc.

Enrolling by invitation

A Trial of Setmelanotide in Acquired Hypothalamic Obesity

Hypothalamic Obesity

United States, Canada, Japan, United Kingdom, Germany, Netherlands
Rhythm Pharmaceuticals, Inc.

Completed

Study of Setmelanotide Effects on QTc (Corrected QT) Interval in Healthy Participants

Healthy

United States
Rhythm Pharmaceuticals, Inc.

Completed

Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects in the MC4R Pathway

Bardet-Biedl Syndrome | POMC Deficiency

Netherlands, United States, Germany, Canada, Puerto Rico, United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants

Overweight

United States
Rhythm Pharmaceuticals, Inc.

Completed

Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Rhythm Pharmaceuticals, Inc.

Completed

Genetic Testing and Phenotypic Characterization of Severely Obese Pediatric and Adult Volunteers

Pro-opiomelanocortin (POMC), Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1) and Leptin Receptor (LepR) Gene Mutations

United States, Israel, Canada, Germany, Greece, Italy, Portugal
Rhythm Diagnostic Systems

Completed

RDS MultiSense® SpO2 Validation Study

Hypoxia

United States
Abdelwahab Hashem

Unknown

Bladder Perforation Post-TURBT: Definition, Incidence and Natural HistoryStudy (TURBT-BP)

Trauma | Bladder Cancer | Injuries | Bladder Urothelial Carcinoma | Perforation of Bladder | Recurrence Tumor | Resection Margin | Seeding, Neoplasm

Egypt
Indonesian Heart Rhythm Society

Unknown

Indonesian Registry on Atrial Fibrillation (OneAF)

Atrial Fibrillation

Indonesia
Kansas City Heart Rhythm Research Foundation
Kansas City Heart Rhythm Institute

Not yet recruiting

Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry (MAVERIC)

Myocarditis | Ventricular Tachycardia (VT) | Premature Ventricular Contractions

United States
Kansas City Heart Rhythm Research Foundation
Kansas City Heart Rhythm Institute

Not yet recruiting

Impact of Steerable Delivery Sheaths on Successful Closure of LA A With AMULET

Stroke | Atrial Fibrillation

United States
Kansas City Heart Rhythm Institute
Kansas City Heart Rhythm Research Foundation

Completed

DOACs for Stroke Prevention Post Ventricular Tachycardia Ablation (STROKE-VT)

Stroke | Ventricular Tachycardia | Premature Ventricular Contraction

United States, India
Rhythm Diagnostic Systems
Clinimark, LLC

Active, not recruiting

RDS MultiSense® SpO2 Calibration

Hypoxia

United States
Kansas City Heart Rhythm Institute

Completed

Comparison of Outcomes Between the Use of Silverlon® Dressing and AQUACEL® AG Dressing Post Cardiac Device Implant

Wounds and Injuries | Infections

United States
Kansas City Heart Rhythm Institute

Terminated

The COVID-19 ICU PRAYER Study

Coronavirus Infection

United States
IHU Strasbourg
Rhythm Diagnostic Systems

Recruiting

Use of RDS MultiSense® in Post-ICU Patients in the COVID-19 Era (MONIREA)

Post ICU Rehabilitation

France
IHU Strasbourg
Rhythm Diagnostic Systems

Completed

Safety and Performance Study of the MultiSense® Ambulatory Telemonitoring System for Non-critical Patient Management (TELESENSE)

Visceral and Digestive Surgery | Post-surgical Monitoring | Post-surgical Rehabilitation

France
IHU Strasbourg
Rhythm Diagnostic Systems

Completed

Evaluation of RDS MultiSense® in Desaturation Analysis in Healthy Volunteers (HYPO)

Hypoxia

France
IHU Strasbourg
Rhythm Diagnostic Systems

Completed

REmote Data Acquisition After SURgery (REDASUR)

Visceral and Digestive Surgery

France
Mayo Clinic
Heart Rhythm Society

Completed

Atrial Fibrillation Screening and Education Study

Atrial Fibrillation

United States
Kansas City Heart Rhythm Institute

Completed

Safety and Efficacy of Left Atrial Appendage Occlusion Devices

Atrial Fibrillation

United States
Omnia Mohammed Hashem

Suspended

Anemia Correction and Fibroblast Growth Factor 23 Levels in Chronic Kidney Disease , and Renal Transplant Patient

Anemia of Chronic Kidney Disease | Endothelial Dysfunction | Left Ventricular Hypertrophy | Fibroblast Growth Factor 23

Egypt
Hatem AbuHashim

Completed

Accuracy of Placenta Accreta Index in Diagnosing Placenta Accreta Spectrum

Placenta Accreta Spectrum

Egypt
Hatem AbuHashim

Unknown

Assessment of Endometrial and Sub-endometrial Vascularity Before and After PRP Infusion in Frozen Embryo Transfer Cycles

Frozen Embryo Transfer
Hatem AbuHashim

Unknown

Accuracy of Three /Four-dimensional Ultrasound in Diagnosing Placenta Accreta Spectrum

Placenta Accreta Spectrum
Hatem AbuHashim

Unknown

Three-dimensional Ultrasonography Versus Hysteroscopy in Evaluation of Uterine Cavity in Infertile Women

Female Infertility

Egypt
Hatem AbuHashim

Unknown

Comparison of Bladder Filling vs. Non-Filling in Cesarean Hysterectomy for Placenta Percreta

Placenta Accreta
Hatem AbuHashim

Unknown

Dose Adjusted vs. Fixed Dose Unilateral Laparoscopic Ovarian Drilling in PCOS Patients

Polycystic Ovary Syndrome
Hatem AbuHashim

Completed

Efficacy of Iron Bisglycinate in Treatment of Iron Deficiency Anemia in Pregnant Women

Iron Deficiency Anemia of Pregnancy

Egypt
Georges Hatem

Completed

Development and Validation of a Short Tool to Assess the Awareness of Pregnancy-induced Hypertension

Pregnancy Related | Hypertension in Pregnancy

Lebanon

Clinical Trials Sponsored by Hythem Nawaytou

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ghana

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations