Clinical Trials Sponsored by Jaakko Sinikumpu

Total 47 results

Jaakko Sinikumpu
Oulu University Hospital; Bioretec Ltd.

Completed

Biodegradable Versus Titanium Nailing in Forearm Shaft Fractures in Children

Forearm Fracture

Finland
Yu Jiakuo

Completed

Prognosis Study of Different Anterior Cruciate Ligament Surgery Methods (ACLRSurgRCT)

Anterior Cruciate Ligament Injuries
Yu Jiakuo

Recruiting

MPFL Reconstruction With or Without Tibial Tubercle Transfer

Patellar Dislocation

China
Kyowa Hakko Bio Co., Ltd.

Recruiting

Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function

Gastrointestinal Diseases | Healthy

Singapore
Loughborough University
Kyowa Hakko Bio Co., Ltd.

Completed

Effects of L-arginine and L-citrulline Supplementation on Muscle Respiration

Dietary Exposure

United Kingdom
Texas Tech University
Kyowa Hakko Bio Co., Ltd.

Completed

Effect of 4 Weeks of Citrulline and Glutathione Supplementation on Arterial Function

Menopause | Cardiovascular Risk Factor

United States
University of Florida
Kyowa Hakko Bio Co., Ltd.

Completed

Oral Glutathione Supplementation in Older Healthy Adults and Its Effect on the Number of Healthy Days Experienced During Four Months of Supplementation Compared to Placebo (GSH)

Improvement in Immune Cell Function in Elderly Humans

United States
Kyowa Hakko Kirin Pharma, Inc.

Completed

Study of KW-0761 (Mogamulizumab) in Subjects With Previously Treated Peripheral T-cell Lymphoma (PTCL)

Peripheral T-Cell Lymphoma

France, United Kingdom, Netherlands, Denmark, Italy, Spain
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study of KRN23 in X-linked Hypophosphatemia

X-linked Hypophosphatemia

United States
Kyowa Hakko Bio Co., Ltd.
University of Cincinnati

Completed

Citicoline Effects on Cortical Membrane Structure and Function

Healthy

United States
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study of Single and Multiple Doses of KHK6640 in Subjects With Prodromal or Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

Belgium, Finland, Netherlands, Serbia, Sweden
University of Florida
Kyowa Hakko Bio Co., Ltd.

Withdrawn

GSH Supplementation on Cold/Flu Symptoms in Older Healthy Adults

Improvement in Immune Cell Function in Elderly Humans
Kyowa Hakko Kirin UK, Ltd.

Completed

A Study of KW-3357 in Congenital Antithrombin Deficiency

Congenital Antithrombin Deficiency

France, Germany, Italy, Sweden, United Kingdom
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study to Evaluate Abuse Potential of Istradefylline

Drug Abuse

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Terminated

Phase 1/2 Study of Anti GM-2 Monoclonal Antibody To Treat Multiple Myeloma

Multiple Myeloma

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin UK, Ltd.

Completed

A Phase I Safety, PK and PD Study of KW-2478 in Patients With Multiple Myeloma, Chronic Lymphocytic Leukaemia or B-cell Non-Hodgkin's Lymphoma

Multiple Myeloma | Chronic Lymphocytic Leukaemia | B-cell Non-Hodgkin's Lymphoma

United Kingdom
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin UK, Ltd.

Completed

A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease

Parkinson's Disease

United Kingdom
Mitsubishi Tanabe Pharma Corporation
Kyowa Hakko Kogyo Co., Ltd.

Completed

Japan Alteplase Clinical Trial (J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator (Alteplase) for Ischemic Stroke

Brain Ischemia | Cerebral Infarction

Japan
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Terminated

Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer

Colorectal Cancer

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Terminated

Study of Anti-HB-EGF Antibody KHK2866 in Subjects With Advanced Solid Tumors and Ovarian Cancer

Neoplasms | Ovarian Neoplasms | Fallopian Tube Neoplasms | Primary Peritoneal Neoplasm

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Terminated

Safety, Tolerability, and Efficacy Study in Subjects With Advanced or Metastatic Breast Cancer

Breast Cancer

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Safety Study to Evaluate KW-2450 in Subjects With Advanced Solid Tumor

Solid Tumor

United States
Kyowa Hakko Bio Co., Ltd.
Biofortis Clinical Research, Inc.

Completed

Cognitive Effects of Citicoline in Men and Women With Age-Associated Memory Impairment

Healthy

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

A 12-week Randomized Study to Evaluate Oral Istradefylline in Subjects With Moderate to Severe Parkinson's Disease (KW-6002)

Idiopathic Parkinson's Disease

United States, Canada, Czechia, Germany, Israel, Italy, Poland, Serbia
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease

Idiopathic Parkinson's Disease

United States, Canada, Czechia, Germany, Israel, Italy, Poland, Serbia
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Safety Study to Evaluate Monoclonal Antibody KW-0761 in Subjects With Peripheral T-cell Lymphoma

Peripheral T-Cell Lymphoma

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Extension Study in Subjects Who Relapsed After Complete Response on Study KW-0761-001

Cutaneous T-cell Lymphoma | Peripheral T-cell Lymphoma

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

The Effect of Rifampin on the Metabolism of Istradefylline in Healthy Volunteers.

Parkinson's Disease

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study of KW-2478 in Combination With Bortezomib in Subjects With Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma

United States, Philippines, United Kingdom
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Effect of Mild Hepatic Impairment on the Pharmacokinetics of Istradefylline

Hepatic Impairment

United States
University of Mississippi Medical Center
Kyowa Hakko Kogyo Co., Ltd.

Completed

Effects of Orotic Acid Derivatives With or Without Glutathione on Allergic Rhinitis

Seasonal Allergic Rhinitis

United States
Memorial Sloan Kettering Cancer Center
Kyowa Hakko Kirin Pharma, Inc.

Completed

Safety, Tolerability, and Immunoregulatory Activity of Mogamulizumab (KW-0761) in Subjects With Advanced and/or Metastatic Solid Tumors

Advanced Solid Tumors | Metastatic Solid Tumors

United States
Kyowa Hakko Bio Co., Ltd.
Oregon Health and Science University

Completed

The Combination Effect of Citicoline and Omega-3

Healthy

United States
University of Texas at Austin
Kyowa Hakko Bio Co., Ltd.

Unknown

Effects of Sustamine(TM) on Cycling Time Trial Performance

Healthy

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.

Completed

Pharmacokinetic Study of KHK7580 in Healthy Adult Volunteers

Healthy Volunteer

China
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.; Teva Pharma

Completed

Phase 1 Study of CEP-37250/KHK2804 in Subjects With Advanced Solid Tumors

Adenocarcinoma of the Pancreas | Solid Tumour | Adenocarcinoma of the Colorectal
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.

Withdrawn

A Phase 4 Study of Brodalumab (KHK4827) in Subjects With Moderate to Severe Plaque Psoriasis

Moderate to Severe Plaque Psoriasis

China
Kyowa Hakko Kirin Pharma, Inc.
Kyowa Kirin Co., Ltd.

Completed

An Extension Study of KRN23 in Adults With X-Linked Hypophosphatemia

X-linked Hypophosphatemia

United States, Canada
Royal Surrey County Hospital NHS Foundation Trust
Kyowa Hakko Kirin UK, Ltd.

Completed

Study of Opioid-Induced Constipation 1 Project (StOIC-1)

Cancer | Opioid-induced Constipation | Cancer Pain

United Kingdom
Kyowa Kirin, Inc.
Kyowa Hakko Kirin UK, Ltd.

Completed

An Extension of Istradefylline in Parkinson's Disease Patients Who Have Completed Studies 6002-EU-007, 6002-US-013 or 6002-US-018

Parkinson's Disease

United States
Kyowa Hakko Kirin Pharma, Inc.
Kyowa Kirin Co., Ltd.

Completed

A Repeated Study of KRN23 in Adults With X-Linked Hypophosphatemia

X-linked Hypophosphatemia

United States, Canada
Royal Surrey County Hospital NHS Foundation Trust
Kyowa Hakko Kirin UK, Ltd.

Completed

Study of Opioid-Induced Constipation 2 Project (StOIC-2)

Cancer | Opioid-induced Constipation | Cancer Pain

United Kingdom
Seoul National University Hospital
Kyowa Hakko Kirin Pharma, Inc.; Jeil-Kirin Pharmaceutical Inc.

Completed

Pharmacokinetic, Pharmacodynamic and Safety Evaluation After Single Oral Administration of KRN1493

Healthy

Korea, Republic of
Assistance Publique - Hôpitaux de Paris
Kyowa Hakko Kogyo (Japan) providing the amino acids

Completed

Citrulline and Protein Metabolism in the Malnourished Elderly People (CIPROAGE)

Elderly | Metabolism

France
H. Lee Moffitt Cancer Center and Research Institute
Kyowa Hakko Kirin Pharma, Inc.

Recruiting

Phototherapy and Mogamulizumab in Early Stage MF (PLIGHT) (PLIGHT)

Mycosis Fungoides

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.; Kyowa Kirin Korea Co., Ltd.

Completed

Study of KHK7580 in Subjects With Secondary Hyperparathyroidism in Asia

Secondary Hyperparathyroidism

China, Hong Kong, Korea, Republic of, Taiwan
Seiji Umemoto, M.D., Ph.D.
Yamaguchi University Hospital; The Japanese Society of Hypertension; Kyowa Hakko...

Completed

Benidipine-based Comparison of Angiotensin Receptors, β-blockers, or Thiazide Diuretics in Hypertensive Patients (COPE)

Cardiovascular Disease

Japan

Clinical Trials Sponsored by Jaakko Sinikumpu

Sponsors and Collaborators

Medical Conditions

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CROs in Finland

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