Clinical Trials Sponsored by Kyowa Hakko Kogyo Co., Ltd.

Total 216 results

Mitsubishi Tanabe Pharma Corporation
Kyowa Hakko Kogyo Co., Ltd.

Completed

Japan Alteplase Clinical Trial (J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator (Alteplase) for Ischemic Stroke

Brain Ischemia | Cerebral Infarction

Japan
University of Mississippi Medical Center
Kyowa Hakko Kogyo Co., Ltd.

Completed

Effects of Orotic Acid Derivatives With or Without Glutathione on Allergic Rhinitis

Seasonal Allergic Rhinitis

United States
Kyowa Hakko Bio Co., Ltd.

Recruiting

Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function

Gastrointestinal Diseases | Healthy

Singapore
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin UK, Ltd.

Completed

A Phase I Safety, PK and PD Study of KW-2478 in Patients With Multiple Myeloma, Chronic Lymphocytic Leukaemia or B-cell Non-Hodgkin's Lymphoma

Multiple Myeloma | Chronic Lymphocytic Leukaemia | B-cell Non-Hodgkin's Lymphoma

United Kingdom
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin UK, Ltd.

Completed

A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease

Parkinson's Disease

United Kingdom
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.

Completed

Pharmacokinetic Study of KHK7580 in Healthy Adult Volunteers

Healthy Volunteer

China
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Terminated

Study of Anti-HB-EGF Antibody KHK2866 in Subjects With Advanced Solid Tumors and Ovarian Cancer

Neoplasms | Ovarian Neoplasms | Fallopian Tube Neoplasms | Primary Peritoneal Neoplasm

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Terminated

Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer

Colorectal Cancer

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Terminated

Safety, Tolerability, and Efficacy Study in Subjects With Advanced or Metastatic Breast Cancer

Breast Cancer

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Safety Study to Evaluate KW-2450 in Subjects With Advanced Solid Tumor

Solid Tumor

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.

Withdrawn

A Phase 4 Study of Brodalumab (KHK4827) in Subjects With Moderate to Severe Plaque Psoriasis

Moderate to Severe Plaque Psoriasis

China
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.

Completed

Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPT (ACTIVE)

Hyperparathyroidism; Secondary, Renal

China
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.

Completed

Efficacy and Safety of Romiplostim in Adult Subjects With Persistent or Chronic Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia

China
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Terminated

Phase 1/2 Study of Anti GM-2 Monoclonal Antibody To Treat Multiple Myeloma

Multiple Myeloma

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study to Evaluate Abuse Potential of Istradefylline

Drug Abuse

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.; Kyowa Kirin Korea Co., Ltd.

Completed

Study of KHK7580 in Subjects With Secondary Hyperparathyroidism in Asia

Secondary Hyperparathyroidism

China, Hong Kong, Korea, Republic of, Taiwan
Loughborough University
Kyowa Hakko Bio Co., Ltd.

Completed

Effects of L-arginine and L-citrulline Supplementation on Muscle Respiration

Dietary Exposure

United Kingdom
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

A 12-week Randomized Study to Evaluate Oral Istradefylline in Subjects With Moderate to Severe Parkinson's Disease (KW-6002)

Idiopathic Parkinson's Disease

United States, Canada, Czechia, Germany, Israel, Italy, Poland, Serbia
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease

Idiopathic Parkinson's Disease

United States, Canada, Czechia, Germany, Israel, Italy, Poland, Serbia
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Safety Study to Evaluate Monoclonal Antibody KW-0761 in Subjects With Peripheral T-cell Lymphoma

Peripheral T-Cell Lymphoma

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Extension Study in Subjects Who Relapsed After Complete Response on Study KW-0761-001

Cutaneous T-cell Lymphoma | Peripheral T-cell Lymphoma

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

The Effect of Rifampin on the Metabolism of Istradefylline in Healthy Volunteers.

Parkinson's Disease

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study of KW-2478 in Combination With Bortezomib in Subjects With Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma

United States, Philippines, United Kingdom
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Effect of Mild Hepatic Impairment on the Pharmacokinetics of Istradefylline

Hepatic Impairment

United States
Kyowa Kirin, Inc.
Kyowa Hakko Kirin UK, Ltd.

Completed

An Extension of Istradefylline in Parkinson's Disease Patients Who Have Completed Studies 6002-EU-007, 6002-US-013 or 6002-US-018

Parkinson's Disease

United States
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.

Completed

Evaluating the Pharmacokinetics and Pharmacodynamics of Romiplostim in Patients With Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia (ITP)

China
Kyowa Hakko Kirin Pharma, Inc.
Kyowa Kirin Co., Ltd.

Completed

An Extension Study of KRN23 in Adults With X-Linked Hypophosphatemia

X-linked Hypophosphatemia

United States, Canada
Kyowa Hakko Kirin Pharma, Inc.
Kyowa Kirin Co., Ltd.

Completed

A Repeated Study of KRN23 in Adults With X-Linked Hypophosphatemia

X-linked Hypophosphatemia

United States, Canada
Texas Tech University
Kyowa Hakko Bio Co., Ltd.

Completed

Effect of 4 Weeks of Citrulline and Glutathione Supplementation on Arterial Function

Menopause | Cardiovascular Risk Factor

United States
University of Florida
Kyowa Hakko Bio Co., Ltd.

Completed

Oral Glutathione Supplementation in Older Healthy Adults and Its Effect on the Number of Healthy Days Experienced During Four Months of Supplementation Compared to Placebo (GSH)

Improvement in Immune Cell Function in Elderly Humans

United States
Kyowa Hakko Bio Co., Ltd.
University of Cincinnati

Completed

Citicoline Effects on Cortical Membrane Structure and Function

Healthy

United States
University of Florida
Kyowa Hakko Bio Co., Ltd.

Withdrawn

GSH Supplementation on Cold/Flu Symptoms in Older Healthy Adults

Improvement in Immune Cell Function in Elderly Humans
Zenyaku Kogyo Co., Ltd.

Completed

A Safety Study of Oral ZSTK474 in Patients With Cancer

Neoplasms

United States
Zenyaku Kogyo Co., Ltd.

Completed

A Study of ZSTK474 in Japanese Patients With Advanced Solid Malignancies

Neoplasms

Japan
Kyowa Hakko Bio Co., Ltd.
Biofortis Clinical Research, Inc.

Completed

Cognitive Effects of Citicoline in Men and Women With Age-Associated Memory Impairment

Healthy

United States
Kyowa Hakko Kirin UK, Ltd.

Completed

A Study of KW-3357 in Congenital Antithrombin Deficiency

Congenital Antithrombin Deficiency

France, Germany, Italy, Sweden, United Kingdom
Assistance Publique - Hôpitaux de Paris
Kyowa Hakko Kogyo (Japan) providing the amino acids

Completed

Citrulline and Protein Metabolism in the Malnourished Elderly People (CIPROAGE)

Elderly | Metabolism

France
Kyowa Hakko Bio Co., Ltd.
Oregon Health and Science University

Completed

The Combination Effect of Citicoline and Omega-3

Healthy

United States
University of Texas at Austin
Kyowa Hakko Bio Co., Ltd.

Unknown

Effects of Sustamine(TM) on Cycling Time Trial Performance

Healthy

United States
Seiji Umemoto, M.D., Ph.D.
Yamaguchi University Hospital; The Japanese Society of Hypertension; Kyowa Hakko...

Completed

Benidipine-based Comparison of Angiotensin Receptors, β-blockers, or Thiazide Diuretics in Hypertensive Patients (COPE)

Cardiovascular Disease

Japan
Kyowa Kirin Korea Co., Ltd.

Terminated

Two-Part, Open-Label, Multi-Center, Phase 1/2 Study of BIW-8962 as Monotherapy in Subjects With Lung Cancer

Phase 1 Portion : Non Small Cell Lung Cancer(NSCLC), Small Cell Lung Cancer(SCLC), Mesothelioma | Phase 2 Portion : Small Cell Lung Cancer(SCLC)

Korea, Republic of
Kyowa Kirin Co., Ltd.

Terminated

Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Study of KW-2449 in Acute Myelogenous Leukemia (AML) (Protocol Number: 2449-US-002)

Acute Myelogenous Leukemia (AML)

United States
Kyowa Kirin Co., Ltd.

Completed

A Phosphate Binder Switch Study of KHK7791 in Hyperphosphatemia Patients on HD

Hyperphosphatemia

Japan
Kyowa Kirin Co., Ltd.

Terminated

A Phase 3 Study of Bardoxolone Methyl in Patients With Diabetic Kidney Disease; AYAME Study

Diabetic Kidney Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

A Phase 1 Study of KHK4083 in Healthy Volunteers and Subjects With Ulcerative Colitis

Healthy Men and Subjects With Ulcerative Colitis

Japan
Kyowa Kirin Co., Ltd.

Active, not recruiting

Study of ME-401 in Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma (NHL)

Indolent B-cell Non-Hodgkin's Lymphoma

Japan
Kyowa Kirin Co., Ltd.

Completed

Phosphate Binder Switch Study of KHK7791 in Hyperphosphatemia Patients on Hemodialysis

Hyperphosphatemia

Japan
Kyowa Kirin Co., Ltd.

Active, not recruiting

Study of ME-401 in Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma

Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma

Japan
Kyowa Kirin Co., Ltd.

Completed

Study of KHK2375 in Subjects With Advanced or Recurrent Breast Cancer

Breast Cancer

Japan
Kyowa Kirin Co., Ltd.

Completed

KRN125 for Mobilization of Hematopoietic Stem Cells

Peripheral Blood Stem Cell Transplantation

Japan

Clinical Trials Sponsored by Kyowa Hakko Kogyo Co., Ltd.

Sponsors and Collaborators

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CROs in Angola

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Drug Interventions

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