Clinical Trials Sponsored by Lawrence Druhan

Total 1419 results

Wuhan Union Hospital, China

Unknown

Anlotinib In Combination With Durvalumab As Sequential Therapy of Thoracic Radiotherapy After Induction Chemotherapy For Extensive-Stage Small Cell Lung Cancer:A Single Arm Study

Small Cell Lung Cancer | Anlotinib | Durvalumab
Wuhan Union Hospital, China

Unknown

Treatment of Acute Severe 2019-nCoV Pneumonia With Immunoglobulin From Cured Patients

2019-nCoV | Immunoglobulin of Cured Patients

China
Wuhan Asia Heart Hospital

Completed

Evaluation of Soluble ST2 in Patients Receiving Primary PCI With ST-elevation Myocardial Infarction

Myocardial Infarction | Shock

China
Wuhan Union Hospital, China

Unknown

Study of Gemcitabine Plus Nab-paclitaxel Versus S1 Plus Nab-paclitaxel in Metastatic Adenocarcinoma of the Pancreas

Pancreatic Cancer | Gemcitabine | Nab-paclitaxel | S1

China
Wuhan Union Hospital, China

Unknown

Clinical Significance of Computer Aided Image Analysis in Treatment Response Evaluation of Lung Cancer

Lung Cancer

China
Wuhan Asia Heart Hospital

Unknown

AI-based Social Software to Manage wARfarin Therapy (AI-SMART)

Anticoagulant-induced Bleeding | Warfarin Sodium Causing Adverse Effects in Therapeutic Use

China
Wuhan Union Hospital, China

Unknown

Clinical Trial of Tumor Cell-derived Microparticles Packaging Chemotherapeutic Drugs to Treat Malignant Pleural Effusion

Malignant Pleural Effusion

China
Changhai Hospital
Wuhan University

Unknown

Efficacy of Oxycodone-propofol Combination Compared With a Fentanyl-propofol Combination on Conscious Sedation Effect and Early Cognitive Function During Therapeutic Endoscopic Retrograde Cholangio-pancreatography

Conscious Sedation During Endoscopic Retrograde Choledochopancreatography

China
Wuhan Asia Heart Hospital

Completed

D-dimer In Patients With atRial Fibrillation rEceiving antiCoagulation Therapy (DIRECT)

Atrial Fibrillation | Strokes Thrombotic

China
Wuhan Asia Heart Hospital

Completed

D-Dimer Determined Anticoagulation INTENSITY in Patients With Mechanical Valve Replacement (3D-INTENSITY)

Heart Valve Disease

China
Wuhan Union Hospital, China

Unknown

Whole Versus Partial Vertebral Body IMRT for Spinal Metastases

Pain
Wuhan Union Hospital, China

Unknown

Multi-center Study on Surgical or Non-surgical Treatment for Children Type 1 Humeral Condyle Fracture

Treatment for Type I Humeral Condyle Fracture
Wuhan Asia Heart Hospital

Completed

High On-treatment Platelet Reactivity Identified by Multiple Platelet Function Assay (HOPEmultiPFA)

Acute Coronary Syndrome

China
Wuhan Union Hospital, China

Completed

Pharmacokinetic Properties and Effect of Food on Pharmacokinetic Properties of the Oral Lafutidine Tablets

Chronic Gastritis
Wuhan Union Hospital, China

Completed

The Efficacy and Safety of Qizhiweitong Granule on Patients With Functional Dyspepsia in a Multi-center Clinical Study

Functional Dyspepsia
Wuhan Union Hospital, China

Unknown

Antiviral Efficacy of the Combination Treatment With Poly IC and Entecavir for Chronic Hepatitis B

Chronic Hepatitis B

China
Wuhan University
Tongji Hospital

Unknown

The Effects of Huang-Lian-Jie-Du-Tang（HLJDT) on the Survival of Patients With Multiple Myeloma in Maintain Therapy (HLJDT-2016)

Multiple Myeloma

China
Yuhan Corporation
Peptron, Inc.

Completed

Safety and Efficacy of YH14617 in Diabetes Mellitus

Diabetes Mellitus

Korea, Republic of
Wuhan Union Hospital, China

Completed

Pharmacokinetics and Tolerability of Minodronic Acid and Food and Age Effects on the Pharmacokinetics

Osteoporosis
Wuhan Asia Heart Hospital

Unknown

A Comparison of the Estimates of Fuwai and Reynolds Risk Model

Coronary Heart Disease and Stroke

China
Wuhan Asia Heart Hospital

Completed

Reference Intervals for Sonoclot Analysis in Chinese

Cardiovascular Diseases

China
Tongji Hospital
Wuhan Central Hospital; Wuhan Hospital of Traditional Chinese Medicine

Recruiting

A Study to Evaluate Efficacy and Safety of Abatacept in Participants of Pemphigus Vulgaris (PV)

Pemphigus Vulgaris

China
Swedish Orphan Biovitrum
IQVIA Pvt. Ltd

Terminated

An 18-month Low-interventional Study to Assess Joint Health in Haemophilia A and B Patients on Prophylaxis With Efmoroctocog Alfa or Eftrenonacog Alfa (JOIN-us)

Hemophilia A | Hemophilia B

Bulgaria, Croatia, Czechia, France, Hungary, Ireland, Italy, Romania, Slovenia, Spain, United Kingdom
Oslo University Hospital
Swedish Orphan Biovitrum

Completed

Trabectedin/Caelyx vs Cisplatin Hypersensitivity in Relapsed Ovarian Cancer Patients Allergic to Platinum (TvsCH)

Chemotherapy-induced Nausea and Vomiting | Chemotherapy Effect | Chemotherapeutic Toxicity | Ovarian Neoplasm | Chemotherapy-induced Neutropenia
Swedish Orphan Biovitrum
Richmond Pharmacology Limited

Terminated

Safety and Tolerability of SOBI002 in Healthy Volunteers Following Single and Repeated Administration

Healthy

United Kingdom
Duke University
Durham VA Medical Center

Completed

Contingency Management for Smoking Cessation in Homeless Smokers

Smoking | Homeless Persons

United States
FDA Office of Orphan Products Development

Completed

Assessment of Chronic Guillain-Barre Syndrome Improvement With Use of 4-aminopyridine

Guillain-Barre Syndrome

United States
FDA Office of Orphan Products Development

Completed

Etanercept for Non-Infectious Lung Injury Following Bone Marrow Transplantation

Pneumonia | Bronchiolitis Obliterans | Respiratory Distress Syndrome, Adult

United States
Duke University
Miami-Dade County Parks and Recreation; Durham Parks and Recreation (Durham...

Recruiting

You & Me Healthy: Youth Empowered Self-Care Substudy (YES) (YES)

Anxiety | Wellness, Psychological

United States
Tongji Hospital
Wuhan Central Hospital; Wuhan Hospital of Traditional Chinese Medicine

Recruiting

A Study Evaluating the Efficacy of Secukinumab 300mg in Chinese Adults With Active Ankylosing Spondylitis

Ankylosing Spondylitis (AS)

China
Wuhan Union Hospital, China
Wuhan Hamilton Bio-technology Co., Ltd, China.

Unknown

Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Severe COVID-19

COVID-19 | 2019 Novel Coronavirus Pneumonia

China
Wuhan Union Hospital, China
Wuhan Bio-Raid Biotechnology Co, Ltd. China

Unknown

Anti-CD30 CAR-T Therapy in Patients With Refractory/Relapsed Lymphocyte Malignancies

Hodgkin Lymphoma | Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Peripheral T Cell Lymphoma | NK/T-cell Lymphoma | Adult T-Cell Lymphoma/Leukaemia

China
Swedish Orphan Biovitrum
Apellis Pharmaceuticals, Inc.

Recruiting

Evaluate the PK Efficacy Safety and Tolerability of Pegcetacoplan in Patients With Thrombotic Microangiopathy

Transplant-Associated Thrombotic Microangiopathy

United States, France, Greece, Italy, Spain
University Hospital, Bonn
Swedish Orphan Biovitrum

Recruiting

Sonography and Haemophilia

Haemophilia | Sonography

Germany
Swedish Orphan Biovitrum
Bioverativ Therapeutics Inc.

Completed

Study of rFVIIIFc for Immune Tolerance Induction (ITI) in Haemophilia A Patients With Inhibitors Who Have Failed Previous ITI Therapies (ReITIrate)

Hemophilia A

Ireland, United Kingdom, Germany, United States, Canada, Slovenia, Sweden
FDA Office of Orphan Products Development

Completed

An Implant for Hearing Loss Due to Removal of Neurofibromatosis 2 Tumors

Neurofibromatosis 2

United States
FDA Office of Orphan Products Development

Completed

Risk-adapted Therapy for Primary Systemic (AL) Amyloidosis

Amyloidosis
FDA Office of Orphan Products Development

Completed

Keratinocyte Growth Factor to Prevent Acute GVHD

Graft-vs-Host Disease

United States
University of California, San Francisco
University of California, Berkeley; The University of Hong Kong; National Institute... and other collaborators

Enrolling by invitation

The Neural Coding of Speech Across Human Languages

Epilepsy | Brain Tumor | Bilingualism | Speech

United States
University Hospital, Bonn
Swedish Orphan Biovitrum

Recruiting

Prevalence of Synovitis in Patients With Haemophilia A (SynoPrev)

Haemophilia A | Synovitis | Hemophilia Arthropathy | Sonography

Germany
Swedish Orphan Biovitrum
Seventh Framework Programme

Completed

Study to Investigate Safety, Efficacy of an Anti-IFNγ mAb in Children With Primary Haemophagocytic Lymphohistiocytosis

Primary Haemophagocytic Lymphohistiocytosis

United States, Sweden, Spain, Italy, Germany, United Kingdom
Swedish Orphan Biovitrum
Seventh Framework Programme

Completed

A Study for Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal Antibody

Hemophagocytic Lymphohistiocytosis

United States, France, Italy, Spain, United Kingdom
Gurhan Taskin

Completed

Ultrasonographic Assessment of Gastric Residual Volume

Critically Ill | Enteral Feeding Intolerance

Turkey
Duke University
Durham VA Medical Center

Completed

Mobile Contingency Management for Smoking Cessation in Returning US Veterans

Smoking | Veterans

United States
Symphogen A/S
Swedish Orphan Biovitrum

Completed

Open Label Trial on the Safety and Efficacy of Sym001 in the Treatment of Immune Thrombocytopenic Purpura (ITP)

Immune Thrombocytopenic Purpura

United States, Belgium, Germany, India, Israel, Poland, Romania, Russian Federation, Serbia, Spain, Ukraine, United Kingdom
FDA Office of Orphan Products Development

Completed

Testing of ADI-PEG in Hepatocellular Carcinoma

Carcinoma, Hepatocellular

United States
FDA Office of Orphan Products Development

Completed

Phase III Randomized Study of the Inhalation of Tobramycin in Patients With Cystic Fibrosis

Cystic Fibrosis | Bacterial Infection
FDA Office of Orphan Products Development

Completed

ADI-PEG in Patients With Metastatic Melanoma

Melanoma | Neoplasm Metastasis

United States
FDA Office of Orphan Products Development

Completed

Study of Albuterol and Oxandrolone in Patients With Facioscapulohumeral Dystrophy (FSHD)

Muscular Dystrophies

United States
FDA Office of Orphan Products Development

Completed

Minocycline in Patients With Huntington's Disease

Huntington's Disease

United States

Clinical Trials Sponsored by Lawrence Druhan

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uganda

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