Clinical Trials Sponsored by Legend Biotech

Total 2005 results

Shanghai Henlius Biotech

Active, not recruiting

The Efficacy and Safety of HLX208 in Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation

Metastatic Colorectal Cancer | mCRC

China
Steba Biotech S.A.

Active, not recruiting

Study of the Efficacy, Safety and Quality of Life After TOOKAD® Soluble (VTP) for Intermediate Risk Prostate Cancer.

Localized Prostate Cancer

United States
NKGen Biotech, Inc.

Active, not recruiting

Safety of SNK01 in Subjects With Pathologically Confirmed Metastatic and/or Unresectable Cancer Refractory to Conventional Therapy

Metastatic Cancer | Advanced Solid Tumor | Advanced Cancer | Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer | Unresectable Carcinoma

United States
Maxigen Biotech Inc.

Completed

Clinical Trial of Cross-linked Hyaluronic Acid Dermal Filler

Hyaluronic Acid | Dermal Fillers

China
SciVision Biotech Inc.

Terminated

Evaluate the Effectiveness of Crosslinked HA on the Adhesion Preventing After Trigger Finger Release Surgery

Trigger Finger | Hyaluronic Acid

Taiwan
Maxigen Biotech Inc.

Completed

Formaderm (Hyaluronic Acid) for Facial Soft Tissue Augmentation

Dermal Filler
CEN Biotech
PiLeJe

Completed

Incidence of Cystitis in Women Consuming a Mixture of Cranberry, Cinnamon, Probiotics

Cystitis | Urinary Tract Infections

France
Aptarion Biotech AG

Completed

Ascending Multiple Intravenous Doses of AON-D21 in Healthy Male Subjects.

Healthy

Germany
Shanghai Henlius Biotech

Completed

Compare Efficacy, Safety and Immunogenicity of HLX02 and Herceptin in Previously Untreated HER2 +Overexpressing Metastatic Breast Cancer

Breast Cancer

China
Shanghai Henlius Biotech

Completed

A Phase 1 Study of HLX20, a Human Monoclonal Antibody Targeting PD-L1Protein in Patients With Advanced Solid Tumors (HLX20)

Advanced Solid Tumors

Australia
Shanghai Henlius Biotech

Completed

Compare Pharmacokinetics, Safety, and Immunogenicity of HLX11 vs. Perjeta in Healthy Chinese Male Subjects

Healthy Male Volunteers

China
Shanghai Henlius Biotech

Terminated

Compare Pharmacokinetic, Safety, Tolerability and Immunogenicity of HLX12 and Ramucirumab in Healthy Male Adult Subjects

Healthy Male Volunteers

China
Shanghai Henlius Biotech

Completed

Study of Efficacy and Safety of HLX03 in Subjects With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

China
Shanghai Henlius Biotech

Withdrawn

A Clinical Study to Compare the Efficacy and Safety of HLX10 in Combination With HLX04 Versus Sorafenib as the First-line Treatment in Patients With Locally Advanced or Metastatic HCC

Hepatocellular Carcinoma (HCC)

China
Shanghai Henlius Biotech

Completed

Evaluate Safety, Tolerability and Pharmacokinetics of HLX22 in Patients With Advanced Solid Tumors Overexpressing HER2

Solid Tumor

China
Shanghai Henlius Biotech

Withdrawn

A Phase III Study to Evaluate Efficacy and Safety of First-Line Treatment With HLX10 + Chemotherapy in Patients With Advanced Cervical Cancer

Cervical Cancer

China
Shanghai Henlius Biotech

Active, not recruiting

A Clinical Study Evaluating the Use of HLX10 in Combination With HLX04 for the Treatment of Advanced Hepatocellular Carcinoma (HCC) Patients

Hepatocellular Carcinoma

China
Krystal Biotech, Inc.

Active, not recruiting

Topical Beremagene Geperpavec (KB103) Gene Therapy to Restore Functional Collagen VII for the Treatment of Dystrophic Epidermolysis Bullosa (GEM-1)

Dystrophic Epidermolysis Bullosa

United States
Cook Biotech Incorporated

Completed

Treatment of Wounds Using Oasis® ECM

Non-healing Wound

United Kingdom
NKGen Biotech, Inc.

Withdrawn

Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers

Sarcoma | Cervical Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | EGF-R Positive Non-Small... and other conditions
Metagone Biotech Inc.

Completed

Assess the Safety and Activity of Combined MG005 and Sorafenib (NEXAVAR®) Treatment With Solid Tumor

Solid Tumor

Taiwan
Galecto Biotech AB

Completed

A First in Human Study to Evaluate the Safety, Tolerability and PK of GB1211 in Healthy Subjects

Safety and Tolerability

United Kingdom
Marinomed Biotech AG

Completed

Demonstration of an Anti-allergic Effect in Subjects Treated With Callergin Nasal Spray in Comparison to Untreated Subjects and Subjects Treated With Vis Alpin® Alpensalz Nasal Spray, All Suffering From Grass Pollen Induced Rhinitis/Rhinoconjunctivitis

Allergic Rhinitis | Allergic Rhinoconjunctivitis

Austria
Moleculin Biotech, Inc.

Completed

Study of WP1220 for the Treatment of Adult Subjects With Cutaneous T-Cell Lymphoma (CTCL)

Cutaneous T-Cell Lymphoma/Mycosis Fungoides

Poland
Shanghai Henlius Biotech

Withdrawn

Evaluate the Efficacy and Safety of HLX01 Versus Mabthera in Patients With Low Tumour Burden Follicular Lymphoma.

CD20-positive Follicular Lymphoma, With Low Tumour Burden
Steba Biotech S.A.

Withdrawn

Evaluation of Efficacy of TOOKAD® (VTP) Versus Active Surveillance for Intermediate Risk Localized Prostate Cancer

Localized Prostate Cancer

United States
HOB Biotech Group

Withdrawn

Clinical Performance of BioCLIA Ro60

Systemic Lupus Erythematosus | Sjogren's Syndrome

United States
NKGen Biotech, Inc.

Completed

Autologous Natural Killer Cells in Subjects With Plaque Psoriasis

Plaque Psoriasis

Mexico
Archigen Biotech Limited

Completed

PK, PD, Safety, and Efficacy of SAIT101 Versus MabThera® Versus Rituxan® in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Korea, Republic of, Hungary, Poland, Czechia, Spain, Bosnia and Herzegovina, Bulgaria, Germany, India, Mexico
Gedea Biotech AB

Completed

Clinical Performance of a Vaginal Pessary (pHyph) in Vulvovaginal Candidiasis

Vulvovaginal Candidiasis

Sweden
JHL Biotech, Inc.

Terminated

A Study of JHL1101 Versus MabThera® in Subjects With Severe Rheumatoid Arthritis

Arthritis, Rheumatoid | Rheumatoid Arthritis

Bosnia and Herzegovina, Bulgaria, Czechia, Germany, Hungary, Lithuania, Poland, Russian Federation, Taiwan, Ukraine, United Kingdom
JHL Biotech, Inc.

Completed

A Comparative Safety and Pharmacokinetic Study of JHL1922 and Pulmozyme® in Healthy Subjects

Healthy Subjects

Netherlands
PCI Biotech AS

Completed

A Phase I/II Safety and Efficacy Study of PCI of Gemcitabine and Chemotherapy in Patients With Cholangiocarcinomas

Cholangiocarcinoma

Germany, France, Norway, United Kingdom
PCI Biotech AS

Completed

Study to Assess Safety, Tolerability and Immune Response of Fimaporfin-induced Photochemical Internalisation of Antigen/Adjuvant

Healthy Volunteer

United Kingdom
Steba Biotech S.A.

Completed

Efficacy and Safety Study of TOOKAD® Soluble for Localised Prostate Cancer Compared to Active Surveillance. (PCM301)

Prostate Cancer

Spain, France, Germany, Netherlands, United Kingdom, Belgium, Finland, Italy, Sweden, Switzerland
PCI Biotech AS

Completed

Safety Study of Amphinex Based Photochemical Internalisation (PCI) of Bleomycin in Patients With Cutaneous Cancer

Head and Neck Neoplasms | Skin Neoplasms

United Kingdom
ASIT Biotech S.A.

Unknown

Clinical Efficacy and Safety of Subcutaneous Immunotherapy With gpASIT+™ in Patients With Grass Pollen-induced Allergic Rhinoconjunctivitis

Hay Fever
Steba Biotech S.A.

Terminated

Safety and Preliminary Efficacy Study of WST11 (Stakel®)-Mediated VTP Therapy in Subjects With CNV Associated With AMD

Macular Degeneration | Choroidal Neovascularization

United States, France
SciVision Biotech Inc.

Completed

The Comparison of HYAJOINT Plus and Hyalgan Hyaluronan Supplement for Knee Osteoarthritis Pain

Osteoarthritis, Knee
Fertility Biotech AG

Completed

Comparative Pharmacokinetics of AFOLIA and US Gonal-f® RFF Redi-ject After Single Subcutaneous Application

Healthy Volunteers

United Kingdom
ZZ Biotech, LLC

Completed

Safety and Pharmacokinetics of Single and Multiple Ascending Doses of 3K3A-APC in Healthy Adult Volunteers

Healthy

Austria
GenMont Biotech Incorporation

Completed

Effects of Genmont Probiotic on Improve the Level of Blood Glucose and Other Diabetic Associate Parameter in Type 2 Diabetes Patients

Type 2 Diabetes

Taiwan
Andromeda Biotech Ltd.

Completed

Efficacy and Safety Study of DiaPep277 in Newly Diagnosed Type 1 Diabetes Adults (DIA-AID2)

Type 1 Diabetes Mellitus

United States, Russian Federation, Israel, Spain, Lithuania, Germany, Austria, Belarus, Canada, Czech Republic, Finland, Hungary, Italy, Poland
SciVision Biotech Inc.

Withdrawn

Safety and Efficacy Study of Lidocaine Mixed Hyaluronate on Nasolabial Folds Correction

Pain | Nasolabial Folds Correction

Taiwan
Steba Biotech S.A.

Terminated

Study Using WST11 in Patients With Non-Resectable or Inoperable Cholangiocarcinoma

Cholangiocarcinoma

France
Folia Biotech Inc.

Unknown

Safety and Reactogenicity of a PAL Combined With Seasonal Flu Vaccine in Healthy Adults

Flu

Canada
Siena Biotech S.p.A.

Completed

A Phase II Safety and Tolerability Study With SEN0014196

Huntington's Disease

Germany
Janssen Biotech, Inc.

Completed

An Observational Study to Evaluate Patient-Reported Experiences of Living With Moderate-to-Severe Plaque Psoriasis

Moderate to Severe Plaque Psoriasis

United States
Steba Biotech S.A.

Completed

Study Using WST11 in Patients With Localized Prostate Cancer

Prostate Cancer

Netherlands, France, United Kingdom
Active Biotech AB

Completed

ABR-217620 in Combination With Docetaxel in Patients With Advanced Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Denmark, Russian Federation

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