Clinical Trials Sponsored by M3DICINE Inc.

Total 48664 results

Hua Medicine Limited

Completed

Drug-Drug Interaction Study of Glucokinase Activator HMS5552 and Metformin in T2DM

Type 2 Diabetes Mellitus

United States
University Medicine Greifswald

Completed

Bioavailability of Paracetamol, Amoxicillin and Talinolol Before, Immediately and One Year After Gastric Bypass Operation

Morbid Obesity

Germany
University Medicine Greifswald

Completed

Effects of Propranolol (vs. Placebo) on Information Processing During Presentation of Emotionally Arousing Pictures (BBEmoMem_G)

Emotions

Germany
University Medicine Greifswald

Completed

Impact of Two Genetic Variants of OATP1B3 or MRP2 or Rifampin on Systemic Disposition and Biological Efficacy of CCK-8

Gastrointestinal Hormones

Germany
Marilia Medicine School

Unknown

Randomized Comparison of Radiological Exposure With TRIPTable® in Patients With Acute Coronary Syndromes (TRIPTABLE)

Angioplasty, Transluminal, Percutaneous Coronary | Acute Coronary Syndromes

Brazil
Hua Medicine Limited

Completed

Beta Cell Function and Related Pharmacodynamics of HMS5552 in T2DM Patients

Type 2 Diabetes

China
University Medicine Greifswald

Completed

Towards Individualized Surgery in Non-focal Congenital Hyperinsulinism (non-focal CHI)

Non-focal Congenital Hyperinsulinism

Germany
University Medicine Greifswald

Completed

Influence of the OATP1B1 and OATP1B3 Genotype on the Hepatic Uptake of Primovist®

MRI | Pharmacokinetics | Liver | Drug Transporter | Gd-EOB-DTPA

Germany
Link Medicine Corporation

Completed

An Escalating Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LNK 754 in Elderly Volunteers and in Subjects With Mild Alzheimer's Disease

Mild Alzheimer's Disease

United States
University Medicine Greifswald

Completed

Millimeter Wave Therapy (MWT) for Analgesia After Total Knee Replacement

Pain | Acute Pain

Germany
University Medicine Greifswald

Completed

Auricular Acupuncture for Pain Relief After Ambulatory Knee Arthroscopy

Postoperative Pain

Germany
University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
Marilia Medicine School

Completed

Palliative Radiotherapy for Bone Metastases: Single Versus Multiple Fractions.

Pain | Bone Metastases

Brazil
University Medicine Greifswald

Unknown

Smoking Interventions in the General Population

Tobacco Smoking
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany
University Medicine Greifswald

Unknown

Impact of Heparin on the Need for Mechanical Ventilation in Neonates

Hemorrhage | Respiration, Artificial

Germany
Manassas Internal Medicine

Terminated

Trial of New Dietary Treatment of Diabetes

Diabetes Mellitus, Type 2

United States
Mylan Pharmaceuticals Inc
Momenta Pharmaceuticals, Inc.

Completed

Extension Study of MYL-1701P-3001 for Safety and Efficacy

Diabetic Macular Edema

India
Cytokind, Inc.
Baylor College of Medicine; Louisiana State University Health Sciences Center... and other collaborators

Completed

Photo-Protection Trial (NB-UVB vs. Placebo) in High-risk Hospitalized COVID-19 Patients

Autoimmune Diseases | Covid19 | Corona Virus Infection | Coagulation Disorder, Blood

United States
University Medicine Greifswald

Not yet recruiting

SHIP-AGE: Frailty, Renal Function, and Multi-component Primary Care in Rural Mecklenburg-Western Pomerania (MV-FIT)

Frailty Syndrome
University Medicine Greifswald

Recruiting

Comparison of the Physical Activity in Cancer Patients Assessed by Questionnaire and Motion Tracker (OncoPhys)

Lymphoma | Colorectal Cancer | Pancreas Cancer

Germany
University Medicine Greifswald

Recruiting

sPERMIdine supplemenTation on Metabolic, Neuronal and Cardiovascular Response to Exercise TRAINING (PERMIT_EX)

Heart Failure, Diastolic

Germany
University Medicine Greifswald

Recruiting

European Disease Registry on Retinopathy of Prematurity (ROP) (EU-ROP)

Retinopathy of Prematurity

Germany, Greece, Austria, Bulgaria, Estonia, France, Kosovo, Poland, Spain, Switzerland, Turkey, Ukraine
Organicell Regenerative Medicine

Completed

Zofin to Treat COVID-19 Long Haulers

COVID-19

United States
University Medicine Greifswald

Active, not recruiting

Adaptive Immune Response to Seasonal Influenza Vaccination (AIGI) ((AIGI))

Seasonal Influenza Vaccination

Germany
University Medicine Greifswald

Active, not recruiting

Adaptive Immune Response to COVID-19 Vaccination (AICOVI)

SARS-CoV-2 Vaccination

Germany
Citrine Medicine Limited

Completed

A Clinical Study to Evaluate the Efficacy and Safety of Pitolisant in the Treatment of EDS in Patients With OSA

Excessive Daytime Sleepiness

China
University Medicine Greifswald

Completed

Impact of OCT1 and CYP2D6 Genotypes on Pharmacokinetics of Berberine in Healthy Volunteers (BERKI-1)

Pharmacokinetic Study in Healthy Volunteers

Germany
University Medicine Greifswald

Completed

Cognitive Training and Brain Stimulation in Prodromal Alzheimer's Disease (AD-Stim)

Mild Cognitive Impairment | Subjective Cognitive Decline

Germany
University Medicine Greifswald

Completed

Acceptance and Efficacy of a Digital Application Among Parents to Control Early Childhood Caries (FU-APP)

Oral Hygiene | Oral Health | Early Childhood Caries

Germany
University Medicine Greifswald

Completed

Neurophysiology of Prophylactic Treatment in Migraine

Migraine

Germany
University Medicine Greifswald

Terminated

Immunoadsorption for Treatment of Alzheimer's Disease (IMAD)

Alzheimer Dementia

Germany
Hua Medicine Limited

Completed

A Clinical Study to Access the Pharmacokinetics of HMS5552 in Renal Impaired Subjects and Healthy Volunteers

Type 2 Diabetes Mellitus

China
University Medicine Greifswald

Unknown

Endoscopic Third Ventriculostomy Versus Ventriculo-peritoneal Shunting in Idiopathic Normal Pressure Hydrocephalus

Normal Pressure Hydrocephalus

Germany
University Medicine Greifswald

Completed

Cerebrospinal Fluid IL-6, IL-8 and PCT as Early Marker of an Intrathecal Infection in Neurosurgical Patients

Intrathecal Infection | External Ventricular Drainage Associated Infection

Germany
Soul Medicine Institute

Completed

Psychological Symptom Change in Veterans After Six Sessions of EFT (Emotional Freedom Techniques)

Stress Disorders, Post-Traumatic

United States
University Medicine Greifswald

Completed

Auricular Stimulation vs. Expressive Writing for Exam Anxiety (AA_EW_Anxi)

Anxiety
University Medicine Greifswald

Completed

Oral Pharmacokinetics of Sulfasalazine, Paracetamol, Fexofenadine and Valsartan Using Different Administration Mediums

Pharmacokinetics | Magnetic Resonance Imaging | Administration, Oral
University Medicine Greifswald

Unknown

Bedside vs. Standard Microbiological Blood Culture Diagnostics - BEMIDIA Study (BEMIDIA)

Sepsis Septic Shock

Germany
University Medicine Greifswald

Withdrawn

Lower Leg Remote Ischemic Preconditioning in Elective Percutaneous Coronary Intervention (PCI) (REMOTE)

Ischemic Heart Disease

Germany
University Medicine Greifswald

Completed

Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects (LOP-MNTX-2009)

Intestinal Obstruction

Germany
University Medicine Greifswald

Completed

Parenteral Nutrition in Patients With Biliopancreatic Mass Lesions (NUPAN)

Pancreatic Cancer | Weight Loss | Biliary Tract Cancer
University Medicine Greifswald

Completed

Pharmacokinetics and Distribution of Dapsone in Leucocytes After Single-dose and Multiple-dose Administration

Methemoglobinemia | Linear IgA Bullous Dermatosis

Germany
University Medicine Greifswald

Completed

Effects of Propranolol on the Encoding and Retrieval of Emotional Material After Single Dose Administration in Healthy Young Subjects

Heart Rate | Memory | Skin Electric Conductance | Amylase | Propanolol

Germany
University Medicine Greifswald

Completed

Absorption of Paracetamol, Talinolol and Amoxicillin After Oral Administration Using Non-caloric and Caloric Water

Gastrointestinal Motility Disorder

Germany
University Medicine Greifswald

Completed

Effects of Methylnaltrexone in Comparison to Naloxone on Loperamide-induced Delay of the Oro-cecal, Whole-gut and Colon Transit Time.

Intestinal Obstruction

Germany
University Medicine Greifswald

Completed

Impact of Exercise on Retinal Microvascular Regulation Measured by Dynamic Vessel Analysis in Healthy Individuals

Healthy Middle-aged Subjects | Age Range Was 18 to 31 Years | Caucasian Whites | Males and Females

Germany
Marilia Medicine School

Completed

Pterygium Treatment Using Single Beta-therapy as Adjuvant Treatment Compared to Conjunctival Autograft

Pterygium

Brazil
Soul Medicine Institute

Completed

Effect of Emotional Freedom Technique and Diaphragmatic Breathing on Post Traumatic Stress Disorder (PTSD)

Stress Disorders, Post-Traumatic

United States
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany

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