Clinical Trials Sponsored by Mapreg

Total 81 results

Mapreg
Eurofins Optimed

Recruiting

RESIST : Administration of MAP4343 in Antidepressant Non-Responders Patients Experiencing a Major Depressive Episode

Depression

France
Marea Therapeutics

Recruiting

Study of MAR001 in Adults With Metabolic Dysfunction

Hypertriglyceridemia

Australia
Aprea Therapeutics

Completed

APR-246 in Combination With Venetoclax and Azacitidine in TP53-Mutant Myeloid Malignancies

Myeloid Malignancy

United States
Aprea Therapeutics

Recruiting

Study Of ATRN-119 In Patients With Advanced Solid Tumors

Advanced Solid Tumor

United States
Aprea Therapeutics

Completed

APR-246 & Azacitidine for the Treatment of TP53 Mutant Myelodysplastic Syndromes (MDS)

MDS

United States, France
Aprea Therapeutics

Completed

Phase 1/2 Study of APR-246 in Combination With Pembrolizumab in Subjects With Solid Tumor Malignancies

Gastric Cancer | NSCLC | Non Small Cell Lung Cancer | Bladder Cancer | Advanced Solid Tumor | Urothelial Carcinoma

United States
Aprea Therapeutics

Not yet recruiting

Study of APR-1051 in Patients With Advanced Solid Tumors

Advanced Solid Tumor
Aprea Therapeutics

Completed

APR-246 in Combination With Azacitidine for TP53 Mutated AML (Acute Myeloid Leukemia) or MDS (Myelodysplastic Syndromes) Following Allogeneic Stem Cell Transplant

Acute Myeloid Leukemia or Myelodysplastic Syndromes

United States
Aprea Therapeutics

Completed

p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246

Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53

United States, France, Spain, Netherlands, United Kingdom, Belgium, Germany, Sweden
Aprea Therapeutics

Completed

p53 Activation in Platinum-Resistant High Grade Serous Ovarian Cancer, a Study of PLD With APR-246

High-grade Serous Ovarian Cancer

Spain, United Kingdom, Belgium
Aprea Therapeutics

Terminated

APR-246 in Combination With Acalabrutinib or Venetoclax Based Therapy in Subjects With R/R Non Hodgkin Lymphomas (NHL) (R/R)

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma

United States
Aprea Therapeutics

Terminated

APR-548 in Combination With Azacitidine for the Treatment of TP53 Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes | MDS

United States
Aprea Therapeutics

Completed

Safety Study of APR-246 in Patients With Refractory Hematologic Cancer or Prostate Cancer

Prostatic Neoplasms | Hematologic Neoplasms

Sweden
Apreo Health, Inc.

Recruiting

First in Human Study to Assess an Implant to Treat Severe Emphysema (BREATHE-1)

Emphysema or COPD

Australia
Maple Leaf Research

Recruiting

Drug-Drug Interaction Study in Trans Women Living With HIV (T-DDI)

Hiv | Transgenderism

Canada
Universitas Sebelas Maret

Not yet recruiting

Dapagliflozin Effect on Rheumatic Mitral Stenosis (Dapa-Rhemis)

Heart Failure | Rheumatic Heart Disease | Mitral Stenosis

Indonesia
Universitas Sebelas Maret

Completed

The Disease Severity In Patients With Psoriasis

Psoriasis

Indonesia
Universitas Sebelas Maret

Completed

The Effects of Mesenchymal Stem Cell Secretome in Lupus Patients

Lupus Erythematosus

Indonesia
Apreo Health, Inc.

Recruiting

Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema (BREATHE-2)

Emphysema or COPD

United Kingdom, Austria, Netherlands
Universitas Sebelas Maret

Not yet recruiting

KurCoSmart Effects on People With Type 2 DM

Inflammation | Diabetes Mellitus, Type 2 | Body Weight | Insulin Resistance

Indonesia
Universitas Sebelas Maret

Recruiting

Modified Foot Exercise to Improve Sensitivity and Perfussion on Type 2 Diabetes Patients

Diabetes Mellitus, Type 2

Indonesia
Universitas Sebelas Maret

Recruiting

Effect of Carvedilol Rapid Up-Titration in Patients With Heart Failure With Reduced Ejection Fraction

Heart Failure With Reduced Ejection Fraction HFrEF

Indonesia
Universitas Sebelas Maret

Completed

The Effects of Mesenchymal Stem Cell Secretome in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Indonesia
Universitas Sebelas Maret

Completed

Study of the Effectiveness of The COVID-19 Vaccine

COVID-19

Indonesia
Universitas Sebelas Maret

Completed

Effect of N-Acetylcysteine on Neutrophil Lymphocyte Ratio And Length of Stay In COVID-19 Patients

COVID-19

Indonesia
Universitas Sebelas Maret

Completed

Videogame Assisted Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Indonesia
Hospital Madre Teresa

Completed

Postoperatory Analgesia After Total Knee Arthroplasty (PAINCONTROL)

PAIN

Brazil
Universitas Sebelas Maret

Completed

The Effect of Melatonin as an Adjuvant Therapy for Preterm Neonates With Sepsis

Sepsis Newborn

Indonesia
Universitas Sebelas Maret

Completed

Effect Of Calcitriol On Neutrophil To Lymphocytes Ratio And High Sensitivity C-Reactive Protein Covid-19 Patients

COVID-19

Indonesia
Universitas Sebelas Maret

Completed

Effect Of Moringa Leaf Extract On Disease Activity In Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Indonesia
Universitas Sebelas Maret

Completed

Channa Striatus Extract on Albumin and Hs-CRP ESRD

Inflammation | End-Stage Renal Disease

Indonesia
Universitas Sebelas Maret

Completed

Evaluating the Efficacy of Channa Striata in Stabilizing eNOS in Patients With Septic.

Sepsis

Indonesia
Universitas Sebelas Maret

Completed

Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio to Predict Carotid Intima-Media Thickness in Chronic Kidney Disease Patients

Chronic Kidney Diseases | Coronary Heart Disease | Dialysis; Complications

Indonesia
Parc de Salut Mar
Fundacion MAPFRE

Completed

Intervention by a Cardiologist and Geriatrician in Elderly Patients After Admission Due to Heart Failure.

Heart Failure

Spain
Marcus Maurer
Charite University, Berlin, Germany

Terminated

Efficacy and Safety of Miltefosine in Antihistamine Resistant Chronic Urticaria (MIARCU)

Chronic Urticaria

Germany
Marcus Maurer

Completed

Profiling Urticaria for the Identification of Subtypes (PURIST)

Non-autoreactive Chronic Spontaneous Urticaria | Autoimmune Chronic Spontaneous Urticaria | Autoreactive, Non-autoimmune Chronic Spontaneous Urticaria

Germany
The Scripps Research Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Mapreg

Withdrawn

MAP4343 Treatment for Alcohol Use Disorder

Alcohol Use Disorder

United States
Marcus Maurer

Completed

Study on Mastocytosis for Rupatadine Treatment (SMART)

Mastocytosis

Germany
Aprea Therapeutics
Jules Bordet Institute

Terminated

A Study of APR-246 in Combination With Dabrafenib in Resistant Patients With BRAF V600 Mutant Melanoma

Melanoma

Belgium
Amazentis SA
Mprex Healthcare Pvt. Ltd.

Not yet recruiting

Bioavailability of Three Mitopure Formulations

Healthy Adults

India
Yusup subagio sutanto

Completed

Pedometer Assisted Physical Activity in Individuals With COPD. A Multicenter Randomized Controlled Trial.

Chronic Obstructive Pulmonary Disease (COPD)

Indonesia
Hospital Universitario Insular Gran Canaria
Fundación MAPFRE Guanarteme

Unknown

Prehabilitation in Bariatric Surgery

Obesity | Bariatric Surgery Candidate

Spain
Nurhasan Agung Prabowo

Recruiting

Lymphocyte Count and High Fluorescent Count (HFLC) Correlate With Liver Disorder in Dengue Fever Patients

Dengue Fever

Indonesia
Groupe Francophone des Myelodysplasies
Aprea Therapeutics

Unknown

Study of the Safety and Efficacy of APR-246 in Combination With Azacitidine

Chronic Myelomonocytic Leukemia | Myeloproliferative Neoplasm | Acute Myeloid Leukemia With Gene Mutations | Myelodysplastic Syndrome With Gene Mutation

France
Marek Straczkowski

Completed

Beta-glucan and Insulin Sensitivity in Obese Humans

Obesity

Poland
Academia Española de Nutrición y Dietética
Fundacion MAPFRE

Completed

Knowledge, Attitudes and Practices on Fad Diets of a Panel of Spanish Consumers: Protocol of a Cross-sectional Study

Knowledge, Attitudes, Practice | Fad Diets

Spain
Mathew S. Maurer
National Institute on Aging (NIA)

Completed

Anemia in Heart Failure With a Preserved Ejection Fraction (HFPEF)

Anemia

United States
Marcus Maurer
Johannes Gutenberg University Mainz

Completed

Desloratadine 5, 10 and 20mg in Patients With Cold Urticaria (AECUDATT)

Urticaria

Germany
Ospedale del Mare
Erbozeta S.p.A

Completed

EFFICACY AND SAFETY OF OVA AND LAVAGE MEDICAL DEVICES IN THE TREATMENT OF NON-SPECIFIC VULVOVAGINITIS

Vaginosis, Bacterial

Italy
Universitas Sebelas Maret
Indonesia Endowment Fund for Education

Not yet recruiting

Efficacy and Safety of Prilocaine 2% and Lidocaine 5% Hyperbaric Against Spinal Anesthesia in Post Cystoscopy Procedure

Anesthesia | Anesthesia; Reaction

Clinical Trials Sponsored by Mapreg

Sponsors and Collaborators

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CROs in Moldova

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Rare Diseases

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